{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T21:17:02Z","timestamp":1793827022837,"version":"4.6.1"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Psychiatric Research"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.jpsychires.2018.07.004","type":"journal-article","created":{"date-parts":[[2018,7,11]],"date-time":"2018-07-11T16:56:36Z","timestamp":1531328196000},"page":"108-113","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["Pets enhance antidepressant pharmacotherapy effects in patients with treatment resistant major depressive disorder"],"prefix":"10.1016","volume":"104","author":[{"given":"Jorge","family":"Mota Pereira","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Fonte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpsychires.2018.07.004_bib1","doi-asserted-by":"crossref","DOI":"10.1186\/1744-859X-10-2","article-title":"Guidelines for rating global assessment of functioning (GAF)","volume":"10","author":"Aas","year":"2011","journal-title":"Ann. Gen. Psychiatr."},{"key":"10.1016\/j.jpsychires.2018.07.004_bib2","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1503\/jpn.150205","article-title":"Why is depression more prevalent in women?","volume":"40","author":"Albert","year":"2015","journal-title":"J. Psychiatry Neurosci. JPN"},{"key":"10.1016\/j.jpsychires.2018.07.004_bib3","article-title":"Using animal-assisted therapy to enrich psychotherapy","volume":"30","author":"Amerine","year":"2016","journal-title":"Adv. Mind Body Med."},{"key":"10.1016\/j.jpsychires.2018.07.004_bib4","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1080\/08927936.2015.1052266","article-title":"An experience sampling approach to investigating associations between pet presence and indicators of psychological wellbeing and mood in older Australians","volume":"28","author":"Bennett","year":"2015","journal-title":"Anthrozo\u00f6s"},{"key":"10.1016\/j.jpsychires.2018.07.004_bib5","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1080\/08927936.2016.1152764","article-title":"Examining differences between homebound older adult pet owners and non-pet owners in depression, systemic inflammation, and executive function","volume":"29","author":"Branson","year":"2016","journal-title":"Anthrozo\u00f6s"},{"key":"10.1016\/j.jpsychires.2018.07.004_bib6","doi-asserted-by":"crossref","first-page":"623203","DOI":"10.1155\/2014\/623203","article-title":"The benefit of pets and animal-assisted therapy to the health of older individuals","volume":"2014","author":"Cherniack","year":"2014","journal-title":"Curr. Gerontol. Geriatr. Res."},{"key":"10.1016\/j.jpsychires.2018.07.004_bib7","first-page":"1","article-title":"Conditions for pets to prevent depression in older adults","author":"Cheung","year":"2017","journal-title":"Aging Ment. Health"},{"key":"10.1016\/j.jpsychires.2018.07.004_bib8","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.psychres.2016.04.034","article-title":"Socio-demographic and clinical predictors of non-response\/non-remission in treatment resistant depressed patients: a systematic review","volume":"240","author":"De Carlo","year":"2016","journal-title":"Psychiatr. Res."},{"key":"10.1016\/j.jpsychires.2018.07.004_bib9","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1080\/13607863.2014.933310","article-title":"Depression in older cat and dog owners: the Nord-Trondelag Health Study (HUNT)-3","volume":"19","author":"Enmarker","year":"2015","journal-title":"Aging Ment. Health"},{"key":"10.1016\/j.jpsychires.2018.07.004_bib10","first-page":"103","article-title":"The therapeutic value of pets","volume":"144","author":"Fitzgerald","year":"1986","journal-title":"West. J. Med."},{"key":"10.1016\/j.jpsychires.2018.07.004_bib11","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1016\/S0002-9149(99)80343-9","article-title":"Pet ownership, social support, and one-year survival after acute myocardial infarction in the Cardiac Arrhythmia Suppression Trial (CAST)","volume":"76","author":"Friedmann","year":"1995","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.jpsychires.2018.07.004_bib12","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1176\/appi.ps.56.4.420","article-title":"Using the GAF as a national mental health outcome measure in the Department of Veterans Affairs","volume":"56","author":"Greenberg","year":"2005","journal-title":"Psychiatr. Serv."},{"key":"10.1016\/j.jpsychires.2018.07.004_bib13","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1136\/jnnp.23.1.56","article-title":"A rating scale for depression","volume":"23","author":"Hamilton","year":"1960","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.jpsychires.2018.07.004_bib14","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1177\/01945902024004009","article-title":"Animal-assisted interventions research: issues and answers","volume":"24","author":"Johnson","year":"2002","journal-title":"West. J. Nurs. Res."},{"key":"10.1016\/j.jpsychires.2018.07.004_bib15","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.gerinurse.2011.12.005","article-title":"Pet ownership and older women: the relationships among loneliness, pet attachment support, human social support, and depressed mood","volume":"33","author":"Krause-Parello","year":"2012","journal-title":"Geriatr. Nurs."},{"key":"10.1016\/j.jpsychires.2018.07.004_bib16","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1177\/0193945913480567","article-title":"Situational factors related to loneliness and loss over time among older pet owners","volume":"35","author":"Krause-Parello","year":"2013","journal-title":"West. J. Nurs. Res."},{"key":"10.1016\/j.jpsychires.2018.07.004_bib17","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1097\/SMJ.0000000000000078","article-title":"Perceptions of companion dog benefits on well-being of US military veterans with HIV\/AIDS","volume":"107","author":"Kruger","year":"2014","journal-title":"South. Med. J."},{"key":"10.1016\/j.jpsychires.2018.07.004_bib18","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/S0140-6736(11)60602-8","article-title":"Major depressive disorder: new clinical, neurobiological, and treatment perspectives","volume":"379","author":"Kupfer","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.jpsychires.2018.07.004_bib19","doi-asserted-by":"crossref","first-page":"2353","DOI":"10.1161\/CIR.0b013e31829201e1","article-title":"Pet ownership and cardiovascular risk: a scientific statement from the American Heart Association","volume":"127","author":"Levine","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.jpsychires.2018.07.004_bib20","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1186\/s12906-017-1844-7","article-title":"Patient benefit of dog-assisted interventions in health care: a systematic review","volume":"17","author":"Lundqvist","year":"2017","journal-title":"BMC Compl. Alternative Med."},{"key":"10.1016\/j.jpsychires.2018.07.004_bib21","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1111\/j.1600-0447.2005.00602.x","article-title":"Treatment-resistant depression: resistant to definition?","volume":"112","author":"Malhi","year":"2005","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.jpsychires.2018.07.004_bib22","doi-asserted-by":"crossref","first-page":"183","DOI":"10.2190\/AG.79.3.a","article-title":"An ecological framework of place: situating environmental gerontology within a life course perspective","volume":"79","author":"Moore","year":"2014","journal-title":"Int. J. Aging Hum. Dev."},{"key":"10.1016\/j.jpsychires.2018.07.004_bib23","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/j.jpsychires.2011.02.005","article-title":"Moderate exercise improves depression parameters in treatment-resistant patients with major depressive disorder","volume":"45","author":"Mota-Pereira","year":"2011","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.jpsychires.2018.07.004_bib24","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1155\/2014\/892048","article-title":"Facebook enhances antidepressant pharmacotherapy effects","volume":"2014","author":"Mota Pereira","year":"2014","journal-title":"Sci. World J."},{"key":"10.1016\/j.jpsychires.2018.07.004_bib25","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.yhbeh.2008.12.002","article-title":"Dog's gaze at its owner increases owner's urinary oxytocin during social interaction","volume":"55","author":"Nagasawa","year":"2009","journal-title":"Horm. Behav."},{"key":"10.1016\/j.jpsychires.2018.07.004_bib26","doi-asserted-by":"crossref","first-page":"16065","DOI":"10.1038\/nrdp.2016.65","article-title":"Major depressive disorder","volume":"2","author":"Otte","year":"2016","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.jpsychires.2018.07.004_bib27","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1159\/000081433","article-title":"Pet ownership and health in older adults: findings from a survey of 2,551 community-based Australians aged 60-64","volume":"51","author":"Parslow","year":"2005","journal-title":"Gerontology"},{"key":"10.1016\/j.jpsychires.2018.07.004_bib28","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1186\/1741-7015-11-129","article-title":"Understanding the somatic consequences of depression: biological mechanisms and the role of depression symptom profile","volume":"11","author":"Penninx","year":"2013","journal-title":"BMC Med."},{"key":"10.1016\/j.jpsychires.2018.07.004_bib29","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.3389\/fpsyg.2017.01796","article-title":"Oxytocin and cortisol levels in dog owners and their dogs are associated with behavioral patterns: an exploratory study","volume":"8","author":"Petersson","year":"2017","journal-title":"Front. Psychol."},{"key":"10.1016\/j.jpsychires.2018.07.004_bib30","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1177\/096973309600300209","article-title":"The right to touch and be touched","volume":"3","author":"Routasalo","year":"1996","journal-title":"Nurs. Ethics"},{"key":"10.1016\/j.jpsychires.2018.07.004_bib31","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1037\/0022-3514.58.6.1081","article-title":"Stressful life events and use of physician services among the elderly: the moderating role of pet ownership","volume":"58","author":"Siegel","year":"1990","journal-title":"J. Pers. Soc. Psychol."},{"key":"10.1016\/j.jpsychires.2018.07.004_bib32","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1080\/09540129948054","article-title":"AIDS diagnosis and depression in the Multicenter AIDS Cohort Study: the ameliorating impact of pet ownership","volume":"11","author":"Siegel","year":"1999","journal-title":"AIDS Care"},{"key":"10.1016\/j.jpsychires.2018.07.004_bib33","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1176\/appi.ajp.2015.1720501","article-title":"The American psychiatric association practice guidelines for the psychiatric evaluation of adults","volume":"172","author":"Silverman","year":"2015","journal-title":"Am. J. Psychiatr."},{"key":"10.1016\/j.jpsychires.2018.07.004_bib34","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.ncl.2010.10.010","article-title":"Diagnosis and treatment of major depressive disorder","volume":"29","author":"Soleimani","year":"2011","journal-title":"Neurol. Clin."},{"key":"10.1016\/j.jpsychires.2018.07.004_bib35","doi-asserted-by":"crossref","first-page":"332","DOI":"10.12968\/bjcn.2017.22.7.332","article-title":"Pet dogs as promoters of wellbeing","volume":"22","author":"While","year":"2017","journal-title":"Br. J. Community Nurs."}],"container-title":["Journal of Psychiatric Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002239561830164X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002239561830164X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,17]],"date-time":"2018-08-17T15:44:52Z","timestamp":1534520692000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002239561830164X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":35,"alternative-id":["S002239561830164X"],"URL":"https:\/\/doi.org\/10.1016\/j.jpsychires.2018.07.004","relation":{},"ISSN":["0022-3956"],"issn-type":[{"value":"0022-3956","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pets enhance antidepressant pharmacotherapy effects in patients with treatment resistant major depressive disorder","name":"articletitle","label":"Article Title"},{"value":"Journal of Psychiatric Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpsychires.2018.07.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}