{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T15:07:03Z","timestamp":1790435223360,"version":"4.1.0"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Psychiatric Research"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.jpsychires.2020.12.069","type":"journal-article","created":{"date-parts":[[2020,12,31]],"date-time":"2020-12-31T08:27:20Z","timestamp":1609403240000},"page":"52-59","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"special_numbering":"C","title":["Association among early life stress, mood features, hopelessness and suicidal risk in bipolar disorder: The potential contribution of insomnia symptoms"],"prefix":"10.1016","volume":"135","author":[{"given":"Laura","family":"Palagini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Miniati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donatella","family":"Marazziti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Verinder","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dieter","family":"Riemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jpsychires.2020.12.069_bib1","first-page":"2","article-title":"The role of childhood trauma in bipolar disorders","volume":"4","author":"Aas","year":"2016","journal-title":"Int. J. Behav. Dev."},{"issue":"4","key":"10.1016\/j.jpsychires.2020.12.069_bib2","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/S2215-0366(15)00544-1","article-title":"Childhood maltreatment and unfavourable clinical outcomesin bipolar disorder: a systematic review and meta-analysis","volume":"3","author":"Agnew-Blais","year":"2016","journal-title":"Lancet Psychiatry"},{"key":"10.1016\/j.jpsychires.2020.12.069_bib3","series-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association","year":"2013"},{"key":"10.1016\/j.jpsychires.2020.12.069_bib4","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.jsmc.2019.01.009","article-title":"Cognitive behavioral therapy for insomnia in depression","volume":"14","author":"Asarnow","year":"2019","journal-title":"Sleep Med Clin"},{"key":"10.1016\/j.jpsychires.2020.12.069_bib5","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.jad.2016.07.045","article-title":"Effect of early trauma on the sleep quality of euthymic bipolar patients","volume":"206","author":"Aubert","year":"2016","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib7","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1037\/h0037562","article-title":"The measurement of pessimism: the hopelessness scale","volume":"42","author":"Beck","year":"1974","journal-title":"J. Consult. Clin. Psychol."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib8","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1207\/s15327752jpa6703_13","article-title":"Comparison of Beck depression inventories -ia and -ii in psychiatric outpatients","volume":"67","author":"Beck","year":"1996","journal-title":"J. Pers. Assess."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib9","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1037\/ccp0000282","article-title":"Treating insomnia in depression: insomnia related factors predict long-term depression trajectories","volume":"86","author":"Bei","year":"2018","journal-title":"J. Consult. Clin. Psychol."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib10","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1007\/s11920-015-0554-4","article-title":"Sleep disturbances as an evidence-based suicide risk factor","volume":"17","author":"Bernert","year":"2015","journal-title":"Curr. Psychiatr. Rep."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib11","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0013-7006(12)70096-9","article-title":"Emotional hyper-reactivity and sleep disturbances in remitted patients with bipolar disorders","volume":"38","author":"Boudebesse","year":"2012","journal-title":"Encephale"},{"key":"10.1016\/j.jpsychires.2020.12.069_bib12","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1097\/01.nmd.0000243824.84651.6c","article-title":"Psychometric properties of the early trauma inventory-self report","volume":"195","author":"Bremner","year":"2007","journal-title":"J. Nerv. Ment. Dis."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib13","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1007\/s10072-016-2620-z","article-title":"Validation study of the Italian version of the insomnia severity index (ISI)","volume":"37","author":"Castronovo","year":"2016","journal-title":"Neurol. Sci."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib65","series-title":"Repertorio delle scale di valutazione in psichiatria","author":"Conti","year":"1999"},{"key":"10.1016\/j.jpsychires.2020.12.069_bib14","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.jad.2015.09.076","article-title":"Sleep, residual mood symptoms, and time to relapse in recovered patients with bipolar disorder","volume":"190","author":"Cretu","year":"2016","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib15","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1111\/acps.12432","article-title":"Critique of a systematic review and meta-analysis of premature mortality in bipolar affective disorder","volume":"132","author":"Delgado","year":"2015","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib16","doi-asserted-by":"crossref","first-page":"991","DOI":"10.4088\/JCP.13m08353","article-title":"Childhood trauma is associated with severe clinical characteristics of bipolar disorders","volume":"74","author":"Etain","year":"2013","journal-title":"J. Clin. Psychiatr."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib17","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.eurpsy.2017.06.013","article-title":"Sleep quality and emotional reactivity cluster in bipolar disorders and impact on functioning","volume":"45","author":"Etain","year":"2017","journal-title":"Eur. Psychiatr."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib18","doi-asserted-by":"crossref","first-page":"91936","DOI":"10.1371\/journal.pone.0091936","article-title":"The burden attributable to mental and substance use disorders as risk factors for suicide: findings from the Global Burden of Disease Study 2010","volume":"9","author":"Ferrari","year":"2014","journal-title":"PloS One"},{"key":"10.1016\/j.jpsychires.2020.12.069_bib19","series-title":"Italiana a cura di Andrea Fossati e Serena Borroni","article-title":"Intervista Clinica Strutturata per i Disturbi del DSM-5","author":"First","year":"2017"},{"key":"10.1016\/j.jpsychires.2020.12.069_bib20","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/acps.12367","article-title":"Sleep in patients with remitted bipolar disorders: a meta-analysis of actigraphy studies","volume":"131","author":"Geoffroy","year":"2015","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib21","series-title":"Beck Depression Inventory-II. Manuale Italiano","author":"Ghisi","year":"2006"},{"key":"10.1016\/j.jpsychires.2020.12.069_bib22","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1111\/acps.12408","article-title":"A systematic review and meta-analysis of premature mortality in bipolar affective disorder","volume":"131","author":"Hayes","year":"2015","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib23","article-title":"Translating basic research knowledge on the biological embedding of early-life stress into novel approaches for the developmental programming of lifelong health","volume":"S0306\u20134530","author":"Heim","year":"2018","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.jpsychires.2020.12.069_bib24","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.smrv.2018.10.006","article-title":"Insomnia as a predictor of mental disorders: a systematic review and meta-analysis","volume":"43","author":"Hertenstein","year":"2019","journal-title":"Sleep Med. Rev."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib25","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.pharep.2018.10.004","article-title":"Childhood trauma in mood disorders: neurobiological mechanisms and implications for treatment","volume":"71","author":"Jaworska-Andryszewska","year":"2019","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib26","first-page":"100193","article-title":"A retrospective examination of sleep disturbance across the course of BipolarDisorder","volume":"4","author":"Kanady","year":"2015","journal-title":"J. Sleep Disord. Ther."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib27","doi-asserted-by":"crossref","first-page":"84282","DOI":"10.1371\/journal.pone.0084282","article-title":"Risk factors for repetition of self-harm: a systematic review of prospective hospital-based studies","volume":"9","author":"Larkin","year":"2014","journal-title":"PloS One"},{"issue":"2","key":"10.1016\/j.jpsychires.2020.12.069_bib28","first-page":"108","article-title":"Suicide in bipolar disorder: a review","volume":"26","author":"Latalova","year":"2014","journal-title":"Psychiatr. Danub."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fpsyt.2019.00019","article-title":"Relationship between depression and subtypes of early life stress in adult psychiatric patients","volume":"10","author":"Martins-Monteverde","year":"2019","journal-title":"Front. Psychiatr."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib31","article-title":"Stress & sleep: a relationship lasting a lifetime","author":"Lo Martire","year":"2019","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib32","doi-asserted-by":"crossref","first-page":"135","DOI":"10.5664\/jcsm.2408","article-title":"Nightmares and dysfunctional beliefs about sleep mediate the effect of insomnia symptoms on suicidal ideation","volume":"9","author":"McCall","year":"2013","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.jpsychires.2020.12.069_bib33","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1080\/87565649109540545","volume":"9","author":"Measso","year":"1993","journal-title":"Dev. Neuropsychol."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib34","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1007\/s11920-020-1130-0","article-title":"Bipolar disorder and suicide: a review","volume":"22","author":"Miller","year":"2020","journal-title":"Curr. Psychiatr. Rep."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib35","series-title":"Insomnia: Psychological Assessment and Management","author":"Morin","year":"1993"},{"key":"10.1016\/j.jpsychires.2020.12.069_bib36","first-page":"1111","article-title":"Quality of life in bipolar disorder: towards a dynamic understanding Psychol Med","volume":"48","author":"Morton","year":"2018"},{"key":"10.1016\/j.jpsychires.2020.12.069_bib37","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.smrv.2014.06.006","article-title":"Sleep-wake disturbance in inter episode bipolar disorder and high-risk individuals: a systematic review and meta-analysis","volume":"20","author":"Ng","year":"2015","journal-title":"Sleep Med. Rev."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib38","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.smrv.2013.05.002","article-title":"The genetics of insomnia--evidence for epigenetic mechanisms?","volume":"18","author":"Palagini","year":"2014","journal-title":"Sleep Med. Rev."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib39","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.sleep.2014.10.013","article-title":"Early-life origin of adult insomnia: does prenatal-early-life stress play a role?","volume":"16","author":"Palagini","year":"2015","journal-title":"Sleep Med."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib40","doi-asserted-by":"crossref","first-page":"12841","DOI":"10.1111\/jsr.12841","article-title":"The key role of insomnia and sleep loss in the dysregulation of multiple systems involved in mood disorders: a proposed model","volume":"10","author":"Palagini","year":"2019","journal-title":"J. Sleep Res."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib41","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.jad.2018.09.011","article-title":"Developmental pathways towards mood disorders in adult life: is there a role for sleep disturbances?","volume":"243","author":"Palagini","year":"2019","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib42","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.comppsych.2018.12.009","article-title":"Insomnia symptoms predict emotional dysregulation, impulsivity and suicidality in depressive bipolar II patients with mixed features","volume":"89","author":"Palagini","year":"2019","journal-title":"Compr. Psychiatr."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib43","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.jad.2020.01.134","article-title":"Association between affective temperaments and mood features in bipolar disorder II: the role of insomnia and chronobiological rhythms desynchronization","volume":"266","author":"Palagini","year":"2020","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib44","doi-asserted-by":"crossref","first-page":"558","DOI":"10.3389\/fpsyt.2020.00558","article-title":"Expert opinions and consensus recommendations for the evaluation and management of insomnia in clinical practice: joint statements of five Italian scientific societies","volume":"11","author":"Palagini","year":"2020","journal-title":"Front. Psychiatr."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib45","series-title":"\u201cTrattato Italiano di Psichiatria\u201d, Seconda edizione","article-title":"Scale di valutazione e di misura dei sintomi psichiatrici","author":"Palma","year":"1999"},{"key":"10.1016\/j.jpsychires.2020.12.069_bib46","first-page":"7","article-title":"Retrospective assessment of childhood trauma: review of the instruments","volume":"45","author":"Pietrini","year":"2010","journal-title":"Riv. Psichiatr."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib47","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1007\/s11920-017-0802-x","article-title":"Insomnia as a precipitating factor in new onset mental illness: a systematic review of recent findings","volume":"19","author":"Pigeon","year":"2017","journal-title":"Curr. Psychiatr. Rep."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib49","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.apnu.2005.12.002","article-title":"Hopelessness and suicide risk emerge in psychiatric nurses suffering from burnout and using specific defense mechanisms","volume":"20","author":"Pompili","year":"2006","journal-title":"Arch. Psychiatr. Nurs."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib64","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1111\/jsr.12594","article-title":"European guideline for the diagnosis and treatment of insomnia","volume":"26","author":"Riemann","year":"2017","journal-title":"J. Sleep Res."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib51","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/j.1399-5618.2011.00917.x","article-title":"The role of disturbed sleep in the early recognition of bipolar disorder: a systematic review","volume":"13","author":"Ritter","year":"2011","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib52","first-page":"743","article-title":"Sleep disturbances in mood disorders","volume":"38","author":"Rumble","year":"2015","journal-title":"Psychiatr. Clin."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib53","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1017\/S1041610213000616","article-title":"A psychological pathway from insomnia to depression among older adults","volume":"25","author":"Sadler","year":"2013","journal-title":"Int. Psychogeriatr."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib54","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1111\/bdi.12778","article-title":"Agitated depression in bipolar disorder","volume":"21","author":"Serra","year":"2019","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib55","doi-asserted-by":"crossref","first-page":"290","DOI":"10.2307\/270723","article-title":"Asymptotic confidence intervals for indirect effects in structural equation models","volume":"13","author":"Sobel","year":"1982","journal-title":"Socio. Methodol."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib56","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1037\/a0024946","article-title":"A test of the bidirectional association between sleep and mood in bipolar disorder and insomnia","volume":"121","author":"Talbot","year":"2012","journal-title":"J. Abnorm. Psychol."},{"issue":"1\u20132","key":"10.1016\/j.jpsychires.2020.12.069_bib57","first-page":"35","article-title":"The effect of early life stress on adult psychiatric disorders","volume":"16","author":"Targum","year":"2019","journal-title":"Innov Clin Neurosci"},{"key":"10.1016\/j.jpsychires.2020.12.069_bib58","first-page":"83","article-title":"Suicidal behavior associated with mixed features in major mood disorders","volume":"43","author":"Tondo","year":"2020","journal-title":"Psychiatr. Clin."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib59","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.jad.2008.06.013","article-title":"Hopelessness across phases of bipolar I or II disorder: a prospective study","volume":"115","author":"Valtonen","year":"2009","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jpsychires.2020.12.069_bib60","doi-asserted-by":"crossref","first-page":"18008","DOI":"10.1038\/nrdp.2018.8","article-title":"Bipolar disorders","volume":"4","author":"Vieta","year":"2018","journal-title":"Nat Rev Dis Primers"},{"key":"10.1016\/j.jpsychires.2020.12.069_bib61","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.5664\/jcsm.4208","article-title":"Hopelessness mediates the relation between insomnia and suicidal ideation","volume":"10","author":"Woosley","year":"2014","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.jpsychires.2020.12.069_bib62","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1192\/bjp.133.5.429","article-title":"A rating scale for mania: reliability, validity and sensitivity","volume":"133","author":"Young","year":"1978","journal-title":"Br. J. Psychiatr."}],"container-title":["Journal of Psychiatric Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022395620311870?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022395620311870?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T11:16:50Z","timestamp":1758367010000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022395620311870"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":60,"alternative-id":["S0022395620311870"],"URL":"https:\/\/doi.org\/10.1016\/j.jpsychires.2020.12.069","relation":{},"ISSN":["0022-3956"],"issn-type":[{"value":"0022-3956","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association among early life stress, mood features, hopelessness and suicidal risk in bipolar disorder: The potential contribution of insomnia symptoms","name":"articletitle","label":"Article Title"},{"value":"Journal of Psychiatric Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpsychires.2020.12.069","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}