{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T11:01:35Z","timestamp":1785841295928,"version":"3.56.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpurol.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pediatric Urology"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1016\/j.jpurol.2018.02.021","type":"journal-article","created":{"date-parts":[[2018,3,21]],"date-time":"2018-03-21T19:43:47Z","timestamp":1521661427000},"page":"279.e1-279.e8","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":56,"title":["Incontinence affects health-related quality of life in children and adolescents with spina bifida"],"prefix":"10.1016","volume":"14","author":[{"given":"Konrad M.","family":"Szymanski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark P.","family":"Cain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Whittam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Kaefer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard C.","family":"Rink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosalia","family":"Misseri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpurol.2018.02.021_bib1","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/j.1365-2982.2005.00737.x","article-title":"A multicentre study of the management of disorders of defecation in patients with spina bifida","volume":"18","author":"Lemelle","year":"2006","journal-title":"Neurogastroenterol Motility"},{"key":"10.1016\/j.jpurol.2018.02.021_bib2","first-page":"825","article-title":"Shunted hydrocephalus has a significant impact on quality of life in children with spina bifida","volume":"5","author":"Ramachandra","year":"2013","journal-title":"Pharm Manag PM R"},{"key":"10.1016\/j.jpurol.2018.02.021_bib3","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1002\/bdra.20360","article-title":"Health care expenditures of children and adults with spina bifida in a privately insured U.S. population","volume":"79","author":"Ouyang","year":"2007","journal-title":"Birth Defects Res A Clin Mol Teratol"},{"key":"10.1016\/j.jpurol.2018.02.021_bib4","doi-asserted-by":"crossref","first-page":"1984","DOI":"10.1016\/j.juro.2009.02.060","article-title":"Health related quality of life in patients with spina bifida: a prospective assessment before and after lower urinary tract reconstruction","volume":"182","author":"MacNeily","year":"2009","journal-title":"J Urol"},{"key":"10.1016\/j.jpurol.2018.02.021_bib5","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1111\/j.1469-8749.2008.02054.x","article-title":"Self-reported health-related quality of life in children and adolescents with myelomeningocele","volume":"50","author":"Muller-Godeffroy","year":"2008","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.jpurol.2018.02.021_bib6","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1097\/01.ju.0000177730.12867.00","article-title":"Lower urinary tract reconstruction for spina bifida \u2013 does it improve health related quality of life?","volume":"174","author":"Macneily","year":"2005","journal-title":"J Urol"},{"key":"10.1016\/j.jpurol.2018.02.021_bib7","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1007\/s11136-006-0032-x","article-title":"Quality of life and continence in patients with spina bifida","volume":"15","author":"Lemelle","year":"2006","journal-title":"Qual Life Res"},{"key":"10.1016\/j.jpurol.2018.02.021_bib8","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1136\/archdischild-2016-312307","article-title":"Quality of life among children with spina bifida in Uganda","volume":"102","author":"Sims-Williams","year":"2017","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.jpurol.2018.02.021_bib9","first-page":"e32","article-title":"The association between urinary continence and quality of life in paediatric patients with spina bifida and tethered cord","volume":"18","author":"Olesen","year":"2013","journal-title":"Paediatr Child Health"},{"key":"10.1016\/j.jpurol.2018.02.021_bib10","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/S1072-7515(98)00091-X","article-title":"The Malone antegrade continence enema procedure in the management of patients with spina bifida","volume":"186","author":"Hensle","year":"1998","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.jpurol.2018.02.021_bib11","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1016\/S0022-5347(01)66297-9","article-title":"The Malone antegrade colonic enema enhances the quality of life in children undergoing urological incontinence procedures","volume":"155","author":"Ellsworth","year":"1996","journal-title":"J Urol"},{"key":"10.1016\/j.jpurol.2018.02.021_bib12","article-title":"Long-term outcome of transanal irrigation for children with spina bifida","author":"Choi","year":"2014","journal-title":"Spinal Cord"},{"issue":"Pt 2","key":"10.1016\/j.jpurol.2018.02.021_bib13","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/j.juro.2016.08.117","article-title":"All incontinence is not created equal: impact of urinary and fecal incontinence on quality of life in adults with spina bifida","volume":"197","author":"Szymanski","year":"2017","journal-title":"J Urol"},{"key":"10.1016\/j.jpurol.2018.02.021_bib14","doi-asserted-by":"crossref","first-page":"2355","DOI":"10.1007\/s11136-015-0988-5","article-title":"QUAlity of Life Assessment in Spina bifida for Adults (QUALAS-A): development and international validation of a novel health-related quality of life instrument","volume":"24","author":"Szymanski","year":"2015","journal-title":"Qual Life Res"},{"key":"10.1016\/j.jpurol.2018.02.021_bib15","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.urology.2015.09.027","article-title":"Quality of life Assessment in Spina Bifida for Children (QUALAS-C): development and validation of a novel health-related quality of life instrument","volume":"87","author":"Szymanski","year":"2016","journal-title":"Urology"},{"key":"10.1016\/j.jpurol.2018.02.021_bib16","first-page":"306","article-title":"Validation of QUALAS-T, a health-related quality of life instrument for teenagers with spina bifida","volume":"70","author":"Szymanski","year":"2017","journal-title":"Cent Eur J Urol"},{"key":"10.1016\/j.jpurol.2018.02.021_bib17","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/j.juro.2015.07.108","article-title":"Quantity, not frequency, predicts bother with urinary incontinence and its impact on quality of life in adults with spina bifida","volume":"195","author":"Szymanski","year":"2016","journal-title":"J Urol"},{"key":"10.1016\/j.jpurol.2018.02.021_bib18","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1002\/sim.6082","article-title":"Multiple hypothesis testing in genomics","volume":"33","author":"Goeman","year":"2014","journal-title":"Stat Med"},{"key":"10.1016\/j.jpurol.2018.02.021_bib19","series-title":"Urinary management and continence outcomes of adults with spina bifida and comparison to children: findings of National Spina Bifida Patient Registry (NSBPR)","first-page":"S73","author":"Wiener","year":"2017"},{"key":"10.1016\/j.jpurol.2018.02.021_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpeds.2014.09.039","article-title":"The national Spina Bifida patient Registry: profile of a large cohort of participants from the first 10 clinics","volume":"166","author":"Sawin","year":"2015","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpurol.2018.02.021_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpurol.2016.06.019","article-title":"Ambulatory patients with spina bifida are 50% more likely to be fecally continent than non-ambulatory patients, particularly after a MACE procedure","volume":"13","author":"Large","year":"2017","journal-title":"J Pediatr Urol"},{"key":"10.1016\/j.jpurol.2018.02.021_bib22","doi-asserted-by":"crossref","first-page":"2239","DOI":"10.1007\/s11136-016-1261-2","article-title":"Clinical significance of physical symptom severity in standardized assessments of patient reported outcomes","volume":"25","author":"Hinami","year":"2016","journal-title":"Qual Life Res"},{"key":"10.1016\/j.jpurol.2018.02.021_bib23","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1023\/A:1026486016212","article-title":"Development of a health-related quality of life instrument for use in children with spina bifida","volume":"6","author":"Parkin","year":"1997","journal-title":"Qual Life Res"},{"key":"10.1016\/j.jpurol.2018.02.021_bib24","series-title":"Deferment in urinary self-catheterization among individuals living with spina bifida: a call to action","author":"Castillo","year":"2017"},{"key":"10.1016\/j.jpurol.2018.02.021_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpurol.2015.11.011","article-title":"Prevalence of nocturnal enuresis and its influence on quality of life in school-aged children","volume":"12","author":"Sarici","year":"2016","journal-title":"J Pediatr Urol"},{"key":"10.1016\/j.jpurol.2018.02.021_bib26","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1007\/s00467-016-3510-6","article-title":"Monosymptomatic nocturnal enuresis in pediatric patients: multidisciplinary assessment and effects of therapeutic intervention","volume":"32","author":"Fagundes","year":"2017","journal-title":"Pediatr Nephrol"},{"key":"10.1016\/j.jpurol.2018.02.021_bib27","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.juro.2017.04.082","article-title":"Transcutaneous electrical nerve stimulation in children with monosymptomatic nocturnal enuresis: A randomized, double-blind, placebo controlled study","volume":"198","author":"Jorgensen","year":"2017","journal-title":"J Urol"},{"key":"10.1016\/j.jpurol.2018.02.021_bib28","doi-asserted-by":"crossref","first-page":"2510","DOI":"10.1016\/j.juro.2010.08.035","article-title":"Is statistical significance sufficient? Importance of interaction and confounding in hypospadias analysis","volume":"184","author":"Braga","year":"2010","journal-title":"J Urol"}],"container-title":["Journal of Pediatric Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1477513118301165?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1477513118301165?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T13:44:47Z","timestamp":1761486287000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1477513118301165"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["S1477513118301165"],"URL":"https:\/\/doi.org\/10.1016\/j.jpurol.2018.02.021","relation":{},"ISSN":["1477-5131"],"issn-type":[{"value":"1477-5131","type":"print"}],"subject":[],"published":{"date-parts":[[2018,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Incontinence affects health-related quality of life in children and adolescents with spina bifida","name":"articletitle","label":"Article Title"},{"value":"Journal of Pediatric Urology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpurol.2018.02.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}