{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T18:13:45Z","timestamp":1783188825102,"version":"3.54.6"},"reference-count":33,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T00:00:00Z","timestamp":1744761600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpurol.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pediatric Urology"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.jpurol.2025.04.009","type":"journal-article","created":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T19:38:47Z","timestamp":1744918727000},"page":"1385-1391","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Is it possible to separate the testicular and ovarian components of an ovotestis?"],"prefix":"10.1016","volume":"21","author":[{"given":"Laurence","family":"Baskin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Baker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4169-2088","authenticated-orcid":false,"given":"Christopher","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald","family":"Cunha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpurol.2025.04.009_bib1","series-title":"Disorders of sexual development. Campbell - Walsh -Wein urology","first-page":"1006","author":"Yu","year":"2021"},{"key":"10.1016\/j.jpurol.2025.04.009_bib2","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.jpurol.2006.03.004","article-title":"Consensus statement on management of intersex disorders","volume":"2","author":"Hughes","year":"2006","journal-title":"J Pediatr Urol"},{"key":"10.1016\/j.jpurol.2025.04.009_bib3","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.jpedsurg.2008.08.013","article-title":"The gonads of 111 South African patients with ovotesticular disorder of sex differentiation","volume":"44","author":"Wiersma","year":"2009","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.jpurol.2025.04.009_bib4","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.diff.2022.03.002","article-title":"Development of the human fetal testis: morphology and expression of cellular differentiation markers","volume":"129","author":"Li","year":"2023","journal-title":"Differentiation"},{"key":"10.1016\/j.jpurol.2025.04.009_bib5","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.diff.2022.10.005","article-title":"Development of the human ovary: fetal through pubertal ovarian morphology, folliculogenesis and expression of cellular differentiation markers","volume":"129","author":"Overland","year":"2023","journal-title":"Differentiation"},{"key":"10.1016\/j.jpurol.2025.04.009_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpurol.2023.12.016","article-title":"Ovotesticular cords and ovotesticular follicles: new histologic markers for human ovotesticular syndrome","author":"Baskin","year":"2024","journal-title":"J Pediatr Urol"},{"key":"10.1016\/j.jpurol.2025.04.009_bib7","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1159\/000466693","article-title":"The spectrum of ovotesticular disorders of sex development in South Africa: a single-centre experience","volume":"87","author":"Ganie","year":"2017","journal-title":"Horm Res Paediatr"},{"key":"10.1016\/j.jpurol.2025.04.009_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpag.2021.02.105","article-title":"Ovotesticular disorder of sex development in Korean children: a single-center analysis over a 30-Year period","author":"Kim","year":"2021","journal-title":"J Pediatr Adolesc Gynecol"},{"key":"10.1016\/j.jpurol.2025.04.009_bib9","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1111\/j.1464-410X.1985.tb07052.x","article-title":"True hermaphroditism. A review of 41 cases with observations on testicular histology and function","volume":"57","author":"Aaronson","year":"1985","journal-title":"Br J Urol"},{"key":"10.1016\/j.jpurol.2025.04.009_bib10","doi-asserted-by":"crossref","first-page":"410","DOI":"10.3389\/fendo.2018.00410","article-title":"Up-To-Date review about minipuberty and overview on hypothalamic-pituitary-gonadal axis activation in fetal and neonatal life","volume":"9","author":"Lanciotti","year":"2018","journal-title":"Front Endocrinol"},{"key":"10.1016\/j.jpurol.2025.04.009_bib11","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2024.1385901","article-title":"Testicular differentiation in 46,XX DSD: an overview of genetic causes","volume":"15","author":"Ferrari","year":"2024","journal-title":"Front Endocrinol"},{"key":"10.1016\/j.jpurol.2025.04.009_bib12","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1159\/000314536","article-title":"Tumor risk in disorders of sex development","volume":"4","author":"Pleskacova","year":"2010","journal-title":"Sex Dev"},{"key":"10.1016\/j.jpurol.2025.04.009_bib13","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1210\/er.2006-0005","article-title":"Germ cell tumors in the intersex gonad: old paths, new directions, moving frontiers","volume":"27","author":"Cools","year":"2006","journal-title":"Endocr Rev"},{"key":"10.1016\/j.jpurol.2025.04.009_bib14","doi-asserted-by":"crossref","first-page":"2480","DOI":"10.1016\/j.jpedsurg.2020.02.014","article-title":"Diagnosis and treatment of the intra-abdominal gonad in the pediatric population: testes, ovaries, dysgenetic gonads, streaks, and ovotestes","volume":"55","author":"de la Calle","year":"2020","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.jpurol.2025.04.009_bib15","article-title":"46, XX Ovotesticular disorder of sex development (true hermaphroditism) with seminoma: a case report","volume":"99","author":"Li","year":"2020","journal-title":"Medicine (Baltim)"},{"key":"10.1016\/j.jpurol.2025.04.009_bib16","article-title":"Ovotesticular disorder with Seminoma","volume":"12","author":"Samantray","year":"2020","journal-title":"Cureus"},{"key":"10.1016\/j.jpurol.2025.04.009_bib17","article-title":"Leydig cell Tumor in a patient with 46,XX disorder of sex development (DSD), ovotesticular: a case report and a review of the literature","volume":"2021","author":"Gretser","year":"2021","journal-title":"Case Rep Pathol"},{"key":"10.1016\/j.jpurol.2025.04.009_bib18","article-title":"True hermaphroditism with dysgerminoma: a case report","volume":"99","author":"Chen","year":"2020","journal-title":"Medicine (Baltim)"},{"key":"10.1016\/j.jpurol.2025.04.009_bib19","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1186\/s12905-022-02137-7","article-title":"True hermaphroditism with sex cord tumor with annular tubules (SCTAT): a rare case report and review of the literature","volume":"22","author":"Shi","year":"2022","journal-title":"BMC Womens Health"},{"key":"10.1016\/j.jpurol.2025.04.009_bib20","doi-asserted-by":"crossref","DOI":"10.3390\/jcm9113555","article-title":"Disorders of sex development: classification, review, and impact on fertility","volume":"9","author":"Acien","year":"2020","journal-title":"J Clin Med"},{"key":"10.1016\/j.jpurol.2025.04.009_bib21","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1007\/s13577-012-0054-3","article-title":"Successful second delivery outcome using refrozen thawed testicular sperm from an infertile male true hermaphrodite with a 46, XX\/46, XY karyotype: case report","volume":"25","author":"Sugawara","year":"2012","journal-title":"Hum Cell"},{"key":"10.1016\/j.jpurol.2025.04.009_bib22","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1159\/000502644","article-title":"Gonadal tissue cryopreservation for children with differences of sex development","volume":"92","author":"Johnson","year":"2019","journal-title":"Horm Res Paediatr"},{"key":"10.1016\/j.jpurol.2025.04.009_bib23","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.jpurol.2016.09.015","article-title":"Fertility in disorders of sex development: a review","volume":"12","author":"Van Batavia","year":"2016","journal-title":"J Pediatr Urol"},{"key":"10.1016\/j.jpurol.2025.04.009_bib24","article-title":"Effectiveness of stem cell therapy for male infertility restoration: a systematic review","author":"Modanlou","year":"2024","journal-title":"J Invest Med"},{"key":"10.1016\/j.jpurol.2025.04.009_bib25","doi-asserted-by":"crossref","DOI":"10.3390\/cells13191642","article-title":"Establishment and characterization of testis organoids with proliferation and differentiation of spermatogonial stem cells into spermatocytes and spermatids","volume":"13","author":"Zhang","year":"2024","journal-title":"Cells"},{"key":"10.1016\/j.jpurol.2025.04.009_bib26","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1007\/BF00735221","article-title":"Effects of estrogens on the testis of transsexuals: a pathological and immunocytochemical study","volume":"411","author":"Sapino","year":"1987","journal-title":"Virchows Arch A Pathol Anat Histopathol"},{"key":"10.1016\/j.jpurol.2025.04.009_bib27","doi-asserted-by":"crossref","first-page":"2095","DOI":"10.1111\/jcmm.17837","article-title":"Environmental oestrogens disrupt testicular descent and damage male reproductive health: mechanistic insight","volume":"27","author":"Li","year":"2023","journal-title":"J Cell Mol Med"},{"key":"10.1016\/j.jpurol.2025.04.009_bib28","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1210\/clinem\/dgaa052","article-title":"Serum anti-mullerian hormone in the prediction of response to hCG stimulation in children with DSD","volume":"105","author":"Lucas-Herald","year":"2020","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpurol.2025.04.009_bib29","first-page":"94","article-title":"Inhibin A production after gonadotropin stimulus: a new method to detect ovarian tissue in ovotesticular disorder of sex development","volume":"71","author":"Steinmetz","year":"2009","journal-title":"Horm Res"},{"key":"10.1016\/j.jpurol.2025.04.009_bib30","doi-asserted-by":"crossref","DOI":"10.1186\/1687-9856-2009-507964","article-title":"FSH injections and ultrasonography determine presence of ovarian components in the evaluation of ovotesticular disorders of sex development","volume":"2009","author":"French","year":"2009","journal-title":"Int J Pediatr Endocrinol"},{"key":"10.1016\/j.jpurol.2025.04.009_bib31","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1007\/s10815-024-03059-z","article-title":"Ethical, legal, social, and policy issues of ovarian tissue cryopreservation in prepubertal girls: a critical interpretive review","volume":"41","author":"Affdal","year":"2024","journal-title":"J Assist Reprod Genet"},{"key":"10.1016\/j.jpurol.2025.04.009_bib32","article-title":"Review paper on fertility preservation in children and prepubertal adolescents with gynaecological cancer","author":"Errasti","year":"2024","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.jpurol.2025.04.009_bib33","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.det.2011.01.010","article-title":"History of mohs surgery","volume":"29","author":"Trost","year":"2011","journal-title":"Dermatol Clin"}],"container-title":["Journal of Pediatric Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1477513125001810?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1477513125001810?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T17:22:30Z","timestamp":1765473750000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1477513125001810"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":33,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["S1477513125001810"],"URL":"https:\/\/doi.org\/10.1016\/j.jpurol.2025.04.009","relation":{},"ISSN":["1477-5131"],"issn-type":[{"value":"1477-5131","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Is it possible to separate the testicular and ovarian components of an ovotestis?","name":"articletitle","label":"Article Title"},{"value":"Journal of Pediatric Urology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpurol.2025.04.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Ltd on behalf of Journal of Pediatric Urology Company.","name":"copyright","label":"Copyright"}]}}