{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T10:44:44Z","timestamp":1782297884852,"version":"3.54.5"},"reference-count":30,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpurol.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pediatric Urology"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.jpurol.2025.07.032","type":"journal-article","created":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T23:49:21Z","timestamp":1753919361000},"page":"1522-1528","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Relationship between serum vitamin B12 levels and primary monosymptomatic nocturnal enuresis: A prospective case-control study"],"prefix":"10.1016","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5797-9115","authenticated-orcid":false,"given":"Abdulgani","family":"G\u00fcly\u00fcz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jpurol.2025.07.032_bib1","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1111\/j.1464-410X.2005.05640.x","article-title":"Enuresis nocturna at age 7.5 years: analysis of prevalence and clinical findings","volume":"96","author":"Butler","year":"2005","journal-title":"BJU Int [Internet]"},{"key":"10.1016\/j.jpurol.2025.07.032_bib2","series-title":"38 Biopsychosocial assessment in children with enuresis [Internet]","author":"Toros","year":"2003"},{"key":"10.1016\/j.jpurol.2025.07.032_bib3","article-title":"Prevalence of nocturnal enuresis in school-age children: the role of personal and parental-related socioeconomic and educational factors","author":"Mahmoodzadeh","year":"2013","journal-title":"Iran J Pediatr [Internet]."},{"issue":"2","key":"10.1016\/j.jpurol.2025.07.032_bib4","doi-asserted-by":"crossref","first-page":"58","DOI":"10.5505\/GJU.2022.87596","article-title":"The relationship between primary monosymptomatic enuresis nocturna and chronotype: a controlled study","volume":"2","author":"Telli","year":"2022","journal-title":"Grand J Urol"},{"issue":"3","key":"10.1016\/j.jpurol.2025.07.032_bib5","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/j.1464-410X.2003.04612.x","article-title":"Characteristics of primary enuresis nocturna in adults: an epidemiologic study","volume":"93","author":"Yeung","year":"2004","journal-title":"BJU Int [Internet]"},{"issue":"7","key":"10.1016\/j.jpurol.2025.07.032_bib6","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1111\/j.1651-2227.2010.01739.x","article-title":"The natural history of daytime urinary incontinence in children: a large British cohort","volume":"99","author":"Swithinbank","year":"2010","journal-title":"Acta Paediatrica, International Journal of Pediatrics [Internet]"},{"issue":"2 SUPPL","key":"10.1016\/j.jpurol.2025.07.032_bib7","article-title":"Causes of vitamin B12 and folate deficiency","volume":"29","author":"Allen","year":"2008","journal-title":"Food Nutr Bull [Internet]"},{"issue":"3","key":"10.1016\/j.jpurol.2025.07.032_bib8","doi-asserted-by":"crossref","first-page":"299","DOI":"10.3390\/nu2030299","article-title":"Vitamin B12 in health and disease","volume":"2","author":"O'Leary","year":"2010","journal-title":"Nutrients [Internet]"},{"issue":"2","key":"10.1016\/j.jpurol.2025.07.032_bib9","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.expneurol.2004.12.020","article-title":"Subacute combined degeneration and beyond with cobalamin (vitamin B12): traditional interpretations and new theories","volume":"192","author":"Scalabrino","year":"2005","journal-title":"Exp Neurol [Internet]"},{"issue":"1","key":"10.1016\/j.jpurol.2025.07.032_bib10","doi-asserted-by":"crossref","DOI":"10.1080\/07853890.2024.2352030","article-title":"Vitamin D and vitamin B12 profiles in children with primary nocturnal enuresis: an analytical cross-sectional study","volume":"56","author":"Atef Abdelsattar Ibrahim","year":"2024","journal-title":"Ann Med"},{"issue":"1","key":"10.1016\/j.jpurol.2025.07.032_bib11","first-page":"87","article-title":"Vitamin B12, folate and iron levels in primary enuresis nocturna","volume":"31","author":"Albayrak","year":"2015","journal-title":"Pakistan J Med Sci [Internet]"},{"issue":"5","key":"10.1016\/j.jpurol.2025.07.032_bib12","article-title":"The role of vitamin B12, 25(OH)D and folate in primary enuresis nocturna: a single center experience","volume":"15","author":"Keles","year":"2024","journal-title":"Annals of Clinical and Analytical Medicine [Internet]"},{"issue":"1","key":"10.1016\/j.jpurol.2025.07.032_bib13","article-title":"Decreased vitamin B12 levels in children with enuresis nocturna","volume":"2012","author":"Altunoluk","year":"2012","journal-title":"Int Sch Res Not [Internet]"},{"issue":"5","key":"10.1016\/j.jpurol.2025.07.032_bib14","first-page":"979","article-title":"Vitamin B12 deficiency","volume":"67","author":"Oh","year":"2003","journal-title":"Am Fam Physician [Internet]"},{"issue":"4","key":"10.1016\/j.jpurol.2025.07.032_bib15","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1002\/nau.22751","article-title":"Standardization of lower urinary tract function terminology in children and adolescents: update report of the standardization committee of the International Child Continence Society","volume":"35","author":"Austin","year":"2016","journal-title":"Neurourol Urodyn [Internet]"},{"issue":"1","key":"10.1016\/j.jpurol.2025.07.032_bib16","doi-asserted-by":"crossref","first-page":"30","DOI":"10.4274\/gulhane.galenos.2023.89421","article-title":"Vitamin B12 and folate levels in children with primary enuresis nocturna","volume":"66","author":"Zeybek","year":"2024","journal-title":"Gulhane Med J"},{"issue":"2","key":"10.1016\/j.jpurol.2025.07.032_bib17","article-title":"Folic acid and vitamin B12 deficiency, two new findings in pediatric enuresis","volume":"33","author":"Kompani","year":"2023","journal-title":"Iranian Journal of Pediatrics 2023"},{"issue":"1","key":"10.1016\/j.jpurol.2025.07.032_bib18","doi-asserted-by":"crossref","DOI":"10.1080\/07853890.2024.2352030","article-title":"Vitamin D and vitamin B12 profiles in children with primary nocturnal enuresis, an analytical cross-sectional study","volume":"56","author":"Atef Abdelsattar Ibrahim","year":"2024","journal-title":"Ann Med"},{"issue":"4","key":"10.1016\/j.jpurol.2025.07.032_bib19","first-page":"2228","article-title":"Combined dietary recommendations, desmopressin and behavioral interventions may Be effective first-line treatment for resolution of enuresis","volume":"12","author":"Ferrara","year":"2015","journal-title":"Urol J [Internet]"},{"key":"10.1016\/j.jpurol.2025.07.032_bib20","series-title":"Modern nutrition in health and disease","first-page":"369","article-title":"Cobalamin (vitamin B12)","author":"Carmel","year":"2014"},{"issue":"2","key":"10.1016\/j.jpurol.2025.07.032_bib21","first-page":"145","article-title":"Vitamin B12 deficiency - a 21st century perspective","volume":"15","author":"Shipton","year":"2015","journal-title":"Clinical Medicine, Journal of the Royal College of Physicians of London [Internet]"},{"issue":"3","key":"10.1016\/j.jpurol.2025.07.032_bib22","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S2352-4642(20)30350-3","article-title":"Identification of genetic loci associated with enuresis nocturna: a genome-wide association study","volume":"5","author":"J\u00f8rgensen","year":"2021","journal-title":"Lancet Child Adolescent Health [Internet]"},{"issue":"11","key":"10.1016\/j.jpurol.2025.07.032_bib23","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/S1474-4422(06)70598-1","article-title":"Vitamin B12, folic acid and the nervous system","volume":"5","author":"Reynolds","year":"2006","journal-title":"Lancet Neurol [Internet]"},{"issue":"3","key":"10.1016\/j.jpurol.2025.07.032_bib24","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.1365-2796.2004.01437.x","article-title":"Holotranscobalamin - first choice assay for the diagnosis of early vitamin B12 deficiency?","volume":"257","author":"Hvas","year":"2005","journal-title":"J Intern Med [Internet]"},{"key":"10.1016\/j.jpurol.2025.07.032_bib25","article-title":"Vitamin B12 deficiency","volume":"3","author":"Green","year":"2017","journal-title":"Nat Rev Dis Primers [Internet]"},{"issue":"2","key":"10.1016\/j.jpurol.2025.07.032_bib26","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1056\/NEJMcp1113996","article-title":"Clinical practice. Vitamin B12 deficiency","volume":"368","author":"Stabler","year":"2013","journal-title":"N Engl J Med [Internet]"},{"issue":"6","key":"10.1016\/j.jpurol.2025.07.032_bib27","first-page":"384","article-title":"Vitamin B12 deficiency: recognition and management","volume":"96","author":"Langan","year":"2017","journal-title":"Am Fam Physician [Internet]"},{"issue":"23","key":"10.1016\/j.jpurol.2025.07.032_bib28","first-page":"3026","article-title":"Association of vitamin B12 levels with sleep quality, insomnia and sleepiness in adult primary health care users in Greece","volume":"11","author":"Bouloukaki","year":"2023","journal-title":"Health Services [Internet]"},{"key":"10.1016\/j.jpurol.2025.07.032_bib29","series-title":"IACAPAP e-textbook of child and adolescent mental health","author":"von Gontard","year":"2012"},{"issue":"12","key":"10.1016\/j.jpurol.2025.07.032_bib30","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1097\/00004583-200012000-00020","article-title":"Nocturnal urinary control, nocturnal enuresis, and behavioral problems in Chinese children aged 6-16 years","volume":"39","author":"Liu","year":"2000","journal-title":"J Am Acad Child Adolesc Psychiatry [Internet]"}],"container-title":["Journal of Pediatric Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1477513125004176?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1477513125004176?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T17:19:57Z","timestamp":1765473597000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1477513125004176"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":30,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["S1477513125004176"],"URL":"https:\/\/doi.org\/10.1016\/j.jpurol.2025.07.032","relation":{},"ISSN":["1477-5131"],"issn-type":[{"value":"1477-5131","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Relationship between serum vitamin B12 levels and primary monosymptomatic nocturnal enuresis: A prospective case-control study","name":"articletitle","label":"Article Title"},{"value":"Journal of Pediatric Urology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpurol.2025.07.032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}