{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T21:29:43Z","timestamp":1791408583277,"version":"4.3.3"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,3,1]],"date-time":"2014-03-01T00:00:00Z","timestamp":1393632000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Reproductive Immunology"],"published-print":{"date-parts":[[2014,3]]},"DOI":"10.1016\/j.jri.2013.04.003","type":"journal-article","created":{"date-parts":[[2013,6,6]],"date-time":"2013-06-06T03:46:33Z","timestamp":1370490393000},"page":"74-79","source":"Crossref","is-referenced-by-count":123,"special_numbering":"C","title":["Trophoblast invasion and oxygenation of the placenta: measurements versus presumptions"],"prefix":"10.1016","volume":"101-102","author":[{"given":"Berthold","family":"Huppertz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregor","family":"Weiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerit","family":"Moser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jri.2013.04.003_bib0005","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1055\/s-0031-1281647","article-title":"Reference values for blood flow velocity in the uterine artery in normal pregnancies from 18 weeks to 42 weeks of gestation calculated by automatic Doppler waveform analysis","volume":"33","author":"Bahlmann","year":"2012","journal-title":"Ultraschall Med."},{"key":"10.1016\/j.jri.2013.04.003_bib0010","series-title":"Pathology of the Human Placenta","author":"Benirschke","year":"2006"},{"key":"10.1016\/j.jri.2013.04.003_bib0015","first-page":"595","article-title":"Cells in the spiral arteries of the pregnant uterus","volume":"90","author":"Boyd","year":"1956","journal-title":"J. Anat."},{"key":"10.1016\/j.jri.2013.04.003_bib0020","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1471-0528.1967.tb14864.x","article-title":"Development and structure of the human placenta from the end of the 3rd month of gestation","volume":"74","author":"Boyd","year":"1967","journal-title":"J. Obstet. Gynaecol. Br. Commonw."},{"key":"10.1016\/j.jri.2013.04.003_bib0025","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1159\/000142564","article-title":"Zum Verhalten der sekundaeren Wand der Uteroplacentargefaesse bei der decidualen Reaktion","volume":"57","author":"Brettner","year":"1964","journal-title":"Acta Anat."},{"key":"10.1016\/j.jri.2013.04.003_bib0030","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1002\/path.1700930218","article-title":"The physiological response of the vessels of the placental bed to normal pregnancy","volume":"93","author":"Brosens","year":"1967","journal-title":"J. Pathol. Bacteriol."},{"key":"10.1016\/j.jri.2013.04.003_bib0035","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.jsgi.2004.03.003","article-title":"Placental oxidative stress: from miscarriage to preeclampsia","volume":"11","author":"Burton","year":"2004","journal-title":"J. Soc. Gynecol. Investig."},{"key":"10.1016\/j.jri.2013.04.003_bib0040","doi-asserted-by":"crossref","first-page":"2954","DOI":"10.1210\/jcem.87.6.8563","article-title":"Uterine glands provide histiotrophic nutrition for the human fetus during the first trimester of pregnancy","volume":"6","author":"Burton","year":"2002","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.jri.2013.04.003_bib0045","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.placenta.2009.02.009","article-title":"Rheological and physiological consequences of conversion of the maternal spiral arteries for uteroplacental blood flow during human pregnancy","volume":"30","author":"Burton","year":"2009","journal-title":"Placenta"},{"issue":"Suppl. A","key":"10.1016\/j.jri.2013.04.003_bib0050","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1053\/plac.1999.0522","article-title":"Oxygen and placental development during the first trimester: implications for the pathophysiology of pre-eclampsia","volume":"21","author":"Caniggia","year":"2000","journal-title":"Placenta"},{"key":"10.1016\/j.jri.2013.04.003_bib0055","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0143-4004(98)90055-8","article-title":"Decidual spiral artery remodelling begins before cellular interaction with cytotrophoblasts","volume":"19","author":"Craven","year":"1998","journal-title":"Placenta"},{"key":"10.1016\/j.jri.2013.04.003_bib0060","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1016\/j.placenta.2006.11.001","article-title":"Implantation in the macaque: expansion of the implantation site during the first week of implantation","volume":"28","author":"Enders","year":"2007","journal-title":"Placenta"},{"key":"10.1016\/j.jri.2013.04.003_bib0065","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1126\/science.277.5332.1669","article-title":"Regulation of human placental development by oxygen tension","volume":"277","author":"Genbacev","year":"1997","journal-title":"Science"},{"key":"10.1016\/j.jri.2013.04.003_bib0070","first-page":"43","article-title":"The morphology of human uteroplacental vasculature","volume":"38","author":"Harris","year":"1966","journal-title":"Contrib. Embryol. Carnegie Inst. Wash."},{"issue":"Suppl. 2","key":"10.1016\/j.jri.2013.04.003_bib0075","doi-asserted-by":"crossref","first-page":"S154","DOI":"10.1016\/j.placenta.2010.11.018","article-title":"IFPA Gabor Than Award lecture: transformation of the spiral arteries in human pregnancy: key events in the remodelling timeline","volume":"32","author":"Harris","year":"2011","journal-title":"Placenta"},{"key":"10.1016\/j.jri.2013.04.003_bib0080","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/0143-4004(87)90031-2","article-title":"Pregnancy-induced structural changes and trophoblastic invasion in the segmental mesometrial arteries of the guinea pig (Cavia porcellus L.)","volume":"8","author":"Hees","year":"1987","journal-title":"Placenta"},{"key":"10.1016\/j.jri.2013.04.003_bib0085","first-page":"13","article-title":"Spiral artery of placenta: development and pathology \u2013 immunohistochemical, microscopical, and electron-microscopic study","volume":"48","author":"Hirano","year":"2002","journal-title":"Kobe J. Med. Sci."},{"key":"10.1016\/j.jri.2013.04.003_bib0090","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1161\/HYPERTENSIONAHA.107.107607","article-title":"Placental origins of preeclampsia: challenging the current hypothesis","volume":"51","author":"Huppertz","year":"2008","journal-title":"Hypertension"},{"key":"10.1016\/j.jri.2013.04.003_bib0095","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1136\/jcp.2008.055277","article-title":"The anatomy of the normal placenta","volume":"61","author":"Huppertz","year":"2008","journal-title":"J. Clin. Pathol."},{"key":"10.1016\/j.jri.2013.04.003_bib0100","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.preghy.2010.10.003","article-title":"Trophoblast differentiation, fetal growth restriction and preeclampsia","volume":"1","author":"Huppertz","year":"2011","journal-title":"Pregn. Hypertens."},{"key":"10.1016\/j.jri.2013.04.003_bib0105","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1159\/000151344","article-title":"Longitudinal determination of serum placental protein 13 during development of preeclampsia","volume":"24","author":"Huppertz","year":"2008","journal-title":"Fetal Diagn. Ther."},{"key":"10.1016\/j.jri.2013.04.003_bib0110","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/j.1469-7580.2008.01036.x","article-title":"Oxygen as modulator of trophoblast invasion","volume":"215","author":"Huppertz","year":"2009","journal-title":"J. Anat."},{"key":"10.1016\/j.jri.2013.04.003_bib0115","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.placenta.2012.01.020","article-title":"Human placentation from nidation to 5 weeks of gestation. Part I: what do we know about formative placental development following implantation?","volume":"33","author":"James","year":"2012","journal-title":"Placenta"},{"key":"10.1016\/j.jri.2013.04.003_bib0120","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1016\/S0002-9440(10)64849-3","article-title":"Onset of maternal arterial blood flow and placental oxidative stress; a possible factor in human early pregnancy failure","volume":"157","author":"Jauniaux","year":"2000","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.jri.2013.04.003_bib0125","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0002-9440(10)63803-5","article-title":"Trophoblastic oxidative stress in relation to temporal and regional differences in maternal placental blood flow in normal and abnormal early pregnancies","volume":"162","author":"Jauniaux","year":"2003","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.jri.2013.04.003_bib0130","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1055\/s-0030-1247600","article-title":"Noninvasive monitoring of placental oxygenation by near-infrared spectroscopy","volume":"27","author":"Kakogawa","year":"2010","journal-title":"Am. J. Perinatol."},{"key":"10.1016\/j.jri.2013.04.003_bib0135","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1095\/biolreprod.102.014977","article-title":"Endovascular trophoblast invasion: implications for the pathogenesis of intrauterine growth retardation and preeclampsia","volume":"69","author":"Kaufmann","year":"2003","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.jri.2013.04.003_bib0140","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1055\/s-2006-958155","article-title":"Measurement of placental oxygenation by transabdominal near-infrared spectroscopy","volume":"24","author":"Kawamura","year":"2007","journal-title":"Am. J. Perinatol."},{"key":"10.1016\/j.jri.2013.04.003_bib0145","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/S0143-4004(97)90000-X","article-title":"Oxygen and placental villous development: origins of fetal hypoxia","volume":"18","author":"Kingdom","year":"1997","journal-title":"Placenta"},{"key":"10.1016\/j.jri.2013.04.003_bib0150","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1161\/01.HYP.32.4.683","article-title":"Human spiral artery renin\u2013angiotensin system","volume":"32","author":"Morgan","year":"1998","journal-title":"Hypertension"},{"key":"10.1016\/j.jri.2013.04.003_bib0155","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1093\/humrep\/deq035","article-title":"Endoglandular trophoblast, an alternative route of trophoblast invasion? Analysis with novel confrontation co-culture models","volume":"25","author":"Moser","year":"2010","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.jri.2013.04.003_bib0160","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.placenta.2010.11.008","article-title":"The art of identification of extravillous trophoblast","volume":"32","author":"Moser","year":"2011","journal-title":"Placenta"},{"key":"10.1016\/j.jri.2013.04.003_bib0165","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1002\/uog.2686","article-title":"A novel approach to first-trimester screening for early pre-eclampsia combining serum PP-13 and Doppler ultrasound","volume":"27","author":"Nicolaides","year":"2006","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"10.1016\/j.jri.2013.04.003_bib0170","first-page":"1000","article-title":"Quantitative estimation of human uterine artery blood flow and pelvic blood flow redistribution in pregnancy","volume":"80","author":"Palmer","year":"1992","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.jri.2013.04.003_bib0175","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/j.placenta.2005.12.006","article-title":"The uterine spiral arteries in human pregnancy: facts and controversies","volume":"27","author":"Pijnenborg","year":"2006","journal-title":"Placenta"},{"key":"10.1016\/j.jri.2013.04.003_bib0180","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1080\/00016340601155056","article-title":"Screening for pre-eclampsia and small for gestational age fetuses at the 11\u201314 weeks scan by uterine artery Dopplers","volume":"86","author":"Pilalis","year":"2007","journal-title":"Acta Obstet. Gynecol. Scand."},{"key":"10.1016\/j.jri.2013.04.003_bib0185","first-page":"283","article-title":"Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy","volume":"80","author":"Rodesch","year":"1992","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.jri.2013.04.003_bib0190","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.ajog.2004.06.066","article-title":"Shunting the intervillous space: new concepts in human uteroplacental vascularization","volume":"192","author":"Schaaps","year":"2005","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"Suppl. A","key":"10.1016\/j.jri.2013.04.003_bib0195","doi-asserted-by":"crossref","first-page":"S75","DOI":"10.1053\/plac.2002.0796","article-title":"Pathogenesis of intrauterine growth restriction (IUGR)-conclusions derived from a European Union Biomed 2 Concerted Action project \u2018Importance of Oxygen Supply in Intrauterine Growth Restricted Pregnancies\u2019\u2014a workshop report","volume":"23","author":"Sibley","year":"2002","journal-title":"Placenta"},{"key":"10.1016\/j.jri.2013.04.003_bib0200","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1159\/000262264","article-title":"Effect of gestational age on fetal and intervillous blood gas and acid-base values in human pregnancy","volume":"1","author":"Soothill","year":"1986","journal-title":"Fetal Ther."},{"key":"10.1016\/j.jri.2013.04.003_bib0205","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/S0140-6736(10)60279-6","article-title":"Pre-eclampsia","volume":"376","author":"Steegers","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.jri.2013.04.003_bib0210","first-page":"1697","article-title":"Susceptibility of human placental syncytiotrophoblastic mitochondria to oxygen-mediated damage in relation to gestational age","volume":"83","author":"Watson","year":"1998","journal-title":"J. Clin. Endocrinol. Metab."}],"container-title":["Journal of Reproductive Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016503781300065X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016503781300065X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,3]],"date-time":"2018-08-03T17:31:00Z","timestamp":1533317460000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016503781300065X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3]]},"references-count":42,"alternative-id":["S016503781300065X"],"URL":"https:\/\/doi.org\/10.1016\/j.jri.2013.04.003","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.718039872.793480641","asserted-by":"object"}]},"ISSN":["0165-0378"],"issn-type":[{"value":"0165-0378","type":"print"}],"subject":[],"published":{"date-parts":[[2014,3]]}}}