{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T05:04:20Z","timestamp":1780981460106,"version":"3.54.1"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Reproductive Immunology"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1016\/j.jri.2022.103677","type":"journal-article","created":{"date-parts":[[2022,7,23]],"date-time":"2022-07-23T17:32:27Z","timestamp":1658597547000},"page":"103677","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Specific activation of embryonic IFNAR1 and endometrial IFNAR2 induced by embryonic IFN\u03c4 directs normal uterine fate for bovine early implantation"],"prefix":"10.1016","volume":"153","author":[{"given":"Xiangguo","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaolei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunze","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boyu","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Longfei","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zili","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xihui","family":"Sheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolong","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hemin","family":"Ni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jri.2022.103677_bib1","doi-asserted-by":"crossref","first-page":"6917","DOI":"10.3168\/jds.2014-8106","article-title":"Recombinant bovine interferon-tau enhances in vitro development of bovine embryos by upregulating expression of connexin 43 and e-cadherin","volume":"97","author":"Bao","year":"2014","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.jri.2022.103677_bib2","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S1642-431X(12)60012-6","article-title":"Interferons and progesterone for establishment and maintenance of pregnancy: interactions among novel cell signaling pathways","volume":"8","author":"Bazer","year":"2008","journal-title":"Reprod. Biol."},{"key":"10.1016\/j.jri.2022.103677_bib3","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1530\/REP-09-0158","article-title":"Comparative aspects of implantation","volume":"138","author":"Bazer","year":"2009","journal-title":"Reproduction"},{"key":"10.1016\/j.jri.2022.103677_bib4","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.theriogenology.2017.01.021","article-title":"The effect of lysophosphatidic acid together with interferon tau on the global transcriptomic profile in bovine endometrial cells","volume":"92","author":"Boruszewska","year":"2017","journal-title":"Theriogenology"},{"key":"10.1016\/j.jri.2022.103677_bib5","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1095\/biolreprod.114.124156","article-title":"Biological roles of interferon tau (ifnt) and type i ifn receptors in elongation of the ovine conceptus","volume":"92","author":"Brooks","year":"2015","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.jri.2022.103677_bib6","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1387\/ijdb.180324mc","article-title":"Somatic cell nuclear transfer: failures, successes and the challenges ahead","volume":"63","author":"Czernik","year":"2019","journal-title":"Int. J. Dev. Biol."},{"key":"10.1016\/j.jri.2022.103677_bib7","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1210\/er.2003-0020","article-title":"Molecular cues to implantation","volume":"25","author":"Dey","year":"2004","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.jri.2022.103677_bib8","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1111\/j.1600-0897.2008.00673.x","article-title":"Control of interferon-tau expression during early pregnancy in ruminants","volume":"61","author":"Ealy","year":"2009","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.jri.2022.103677_bib9","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1111\/rda.13667","article-title":"Recent progress in bovine in vitro-derived embryo cryotolerance: impact of in vitro culture systems, advances in cryopreservation and future considerations","volume":"55","author":"Ferr\u00e9","year":"2020","journal-title":"Reprod. Domest. Anim. Zuchthyg."},{"key":"10.1016\/j.jri.2022.103677_bib10","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1530\/REP-17-0396","article-title":"Altered mirna-profile dependent on art outcome in early pregnancy targets wnt-pathway","volume":"154","author":"Freis","year":"2017","journal-title":"Reproduction"},{"key":"10.1016\/j.jri.2022.103677_bib11","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.theriogenology.2017.04.008","article-title":"Hepatoma-derived growth factor: protein quantification in uterine fluid, gene expression in endometrial-cell culture and effects on in vitro embryo development, pregnancy and birth","volume":"96","author":"G\u00f3mez","year":"2017","journal-title":"Theriogenology"},{"key":"10.1016\/j.jri.2022.103677_bib12","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1387\/ijdb.130348mb","article-title":"Role of uterine stromal-epithelial crosstalk in embryo implantation","volume":"58","author":"Hantak","year":"2014","journal-title":"Int. J. Dev. Biol."},{"key":"10.1016\/j.jri.2022.103677_bib13","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.1084\/jem.20182295","article-title":"Inherited ifnar1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines","volume":"216","author":"Hernandez","year":"2019","journal-title":"J. Exp. Med."},{"issue":"Suppl 5","key":"10.1016\/j.jri.2022.103677_bib14","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1093\/humrep\/15.suppl_5.87","article-title":"Risks of in-vitro production of cattle and swine embryos: aberrations in chromosome numbers, ribosomal rna gene activation and perinatal physiology","volume":"15","author":"Hyttel","year":"2000","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.jri.2022.103677_bib15","doi-asserted-by":"crossref","first-page":"8396","DOI":"10.3168\/jds.2017-14251","article-title":"Hot topic: pregnancy-induced expression of interferon-stimulated genes in the cervical and vaginal mucosal membranes","volume":"101","author":"Kunii","year":"2018","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.jri.2022.103677_bib16","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.placenta.2007.09.012","article-title":"Calcitonin promotes outgrowth of trophoblast cells on endometrial epithelial cells: involvement of calcium mobilization and protein kinase c activation","volume":"29","author":"Li","year":"2008","journal-title":"Placenta"},{"issue":"Suppl 1","key":"10.1016\/j.jri.2022.103677_bib17","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1017\/S1751731114000470","article-title":"Maternal-embryo interaction leading up to the initiation of implantation of pregnancy in cattle","volume":"8","author":"Lonergan","year":"2014","journal-title":"Anim. Int. J. Anim. Biosci."},{"key":"10.1016\/j.jri.2022.103677_bib18","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1071\/RD19430","article-title":"Type i interferon receptors and interferon-tau-stimulated genes in peripheral blood mononuclear cells and polymorphonuclear leucocytes during early pregnancy in beef heifers","volume":"32","author":"Melo","year":"2020","journal-title":"Reprod. Fertil. Dev."},{"key":"10.1016\/j.jri.2022.103677_bib19","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0093-691X(99)00237-X","article-title":"Alterations of expression of developmentally important genes in preimplantation bovine embryos by in vitro culture conditions: implications for subsequent development","volume":"53","author":"Niemann","year":"2000","journal-title":"Theriogenology"},{"key":"10.1016\/j.jri.2022.103677_bib20","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1126\/science.1071601","article-title":"Deciphering the cross-talk of implantation: advances and challenges","volume":"296","author":"Paria","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.jri.2022.103677_bib21","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1021\/acschembio.9b00912","article-title":"Identification of interferon receptor ifnar2 as a novel hcv entry factor by using chemical probes","volume":"15","author":"Qing","year":"2020","journal-title":"ACS Chem. Biol."},{"key":"10.1016\/j.jri.2022.103677_bib22","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.3389\/fimmu.2019.02391","article-title":"Stimulation of mononuclear cells through toll-like receptor 9 induces release of microvesicles expressing double-stranded DNA and galectin 3-binding protein in an interferon-alpha-dependent manner","volume":"10","author":"Rasmussen","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jri.2022.103677_bib23","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.semcdb.2007.10.007","article-title":"Interferons and the maternal-conceptus dialog in mammals","volume":"19","author":"Roberts","year":"2008","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.jri.2022.103677_bib24","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1095\/biolreprod.102.004267","article-title":"Expression of interferon receptor subunits, ifnar1 and ifnar2, in the ovine uterus","volume":"67","author":"Rosenfeld","year":"2002","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.jri.2022.103677_bib25","doi-asserted-by":"crossref","first-page":"5941","DOI":"10.3168\/jds.2015-10070","article-title":"The role of progesterone and conceptus-derived factors in uterine biology during early pregnancy in ruminants","volume":"99","author":"Spencer","year":"2016","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.jri.2022.103677_bib26","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1530\/REP-07-0327","article-title":"Genes involved in conceptus-endometrial interactions in ruminants: insights from reductionism and thoughts on holistic approaches","volume":"135","author":"Spencer","year":"2008","journal-title":"Reproduction"},{"key":"10.1016\/j.jri.2022.103677_bib27","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s12861-018-0176-2","article-title":"Effects of sex on response of the bovine preimplantation embryo to insulin-like growth factor 1, activin a, and wnt7a","volume":"18","author":"Tr\u00edbulo","year":"2018","journal-title":"BMC Dev. Biol."},{"key":"10.1016\/j.jri.2022.103677_bib28","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/nrg1808","article-title":"Roadmap to embryo implantation: clues from mouse models","volume":"7","author":"Wang","year":"2006","journal-title":"Nat. Rev. Genet.."},{"key":"10.1016\/j.jri.2022.103677_bib29","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1111\/rda.13118","article-title":"Expression of ifnar1 and ifnar2 in cattle placenta during early pregnancy","volume":"53","author":"Wang","year":"2018","journal-title":"Reprod. Domest. Anim. Zuchthyg."},{"key":"10.1016\/j.jri.2022.103677_bib30","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.theriogenology.2017.12.030","article-title":"Expression and function of muc1 in uterine tissues during early pregnancy in sheep after natural oestrous or artificially-induced oestrous","volume":"108","author":"Wang","year":"2018","journal-title":"Theriogenology"},{"key":"10.1016\/j.jri.2022.103677_bib31","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1111\/rda.12169","article-title":"A potential autocrine role for interferon tau in ovine trophectoderm","volume":"48","author":"Wang","year":"2013","journal-title":"Reprod. Domest. Anim. Zuchthyg."},{"key":"10.1016\/j.jri.2022.103677_bib32","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1111\/j.1439-0531.2007.01009.x","article-title":"Expression of interferon-tau mrna in bovine embryos derived from different procedures","volume":"44","author":"Yao","year":"2009","journal-title":"Reprod. Domest. Anim. Zuchthyg."}],"container-title":["Journal of Reproductive Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165037822002066?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165037822002066?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T04:30:25Z","timestamp":1759033825000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165037822002066"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":32,"alternative-id":["S0165037822002066"],"URL":"https:\/\/doi.org\/10.1016\/j.jri.2022.103677","relation":{},"ISSN":["0165-0378"],"issn-type":[{"value":"0165-0378","type":"print"}],"subject":[],"published":{"date-parts":[[2022,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Specific activation of embryonic IFNAR1 and endometrial IFNAR2 induced by embryonic IFN\u03c4 directs normal uterine fate for bovine early implantation","name":"articletitle","label":"Article Title"},{"value":"Journal of Reproductive Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jri.2022.103677","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"103677"}}