{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T03:08:29Z","timestamp":1772939309858,"version":"3.50.1"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Reproductive Immunology"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1016\/j.jri.2022.103780","type":"journal-article","created":{"date-parts":[[2022,11,28]],"date-time":"2022-11-28T00:33:05Z","timestamp":1669595585000},"page":"103780","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Effects of sequential cleavage and blastocyst embryo transfer on pregnancy outcomes in patients with poor ovarian response"],"prefix":"10.1016","volume":"155","author":[{"given":"Yu-Ling","family":"Hu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Hong","family":"Geng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang-Qian","family":"Meng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hai-Jiao","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enoch Appiah","family":"Adu-Gyamfi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhao-Hui","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Wan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Bin","family":"Ding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jri.2022.103780_bib1","first-page":"21","article-title":"Novel physiology and definition of poor ovarian response; clinical recommendations","author":"Abu-Musa","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jri.2022.103780_bib2","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s10815-008-9237-y","article-title":"Interval double transfer improves treatment success in patients with repeated IVF\/ET failures","volume":"25","author":"Almog","year":"2008","journal-title":"J. Assist Reprod. Genet"},{"key":"10.1016\/j.jri.2022.103780_bib3","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1093\/humrep\/der037","article-title":"The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting","volume":"26","author":"Alpha Scientists in Reproductive Medicine and ESHRE Special Interest Group of Embryology","year":"2011","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.jri.2022.103780_bib4","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1016\/S0015-0282(00)01549-1","article-title":"Double (consecutive) transfer of early embryos and blastocysts: aims and results","volume":"74","author":"Ashkenazi","year":"2000","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jri.2022.103780_bib5","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1080\/00273171.2011.568786","article-title":"An introduction to propensity score methods for reducing the effects of confounding in observational studies","volume":"46","author":"Austin","year":"2011","journal-title":"Multivar. Behav. Res"},{"key":"10.1016\/j.jri.2022.103780_bib6","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.ejogrb.2016.05.027","article-title":"A randomized, single-blind, prospective trial comparing three different gonadotropin doses with or without addition of letrozole during ovulation stimulation in patients with poor ovarian response","volume":"203","author":"Bastu","year":"2016","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"10.1016\/j.jri.2022.103780_bib7","first-page":"8","article-title":"Impact of endometrial preparation protocols for frozen embryo transfer on live birth rates","author":"Cerrillo","year":"2017","journal-title":"Rambam Maimonides Med. J."},{"key":"10.1016\/j.jri.2022.103780_bib8","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1016\/j.fertnstert.2005.06.035","article-title":"Elective single blastocyst transfer reduces twin rates without compromising pregnancy rates","volume":"84","author":"Criniti","year":"2005","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jri.2022.103780_bib9","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2021.785658","article-title":"Analysis of biochemical and clinical pregnancy loss between frozen-thawed embryo transfer of blastocysts and day 3 cleavage embryos in young women: a comprehensive comparison","volume":"12","author":"Dai","year":"2021","journal-title":"Front Endocrinol."},{"key":"10.1016\/j.jri.2022.103780_bib10","article-title":"Update on the management of poor ovarian response in IVF: the shift from Bologna criteria to the Poseidon concept","volume":"14","author":"Drakopoulos","year":"2020","journal-title":"Ther. Adv. Reprod. Health"},{"key":"10.1016\/j.jri.2022.103780_bib11","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1016\/j.fertnstert.2021.06.019","article-title":"Mean differences in maternal body mass index and recurrent pregnancy loss: a systematic review and meta-analysis of observational studies","volume":"116","author":"Eapen","year":"2021","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jri.2022.103780_bib12","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.rbmo.2012.10.004","article-title":"Day-2 and day-3 sequential transfer improves pregnancy rate in patients with repeated IVF-embryo transfer failure: a retrospective case-control study","volume":"26","author":"Fang","year":"2013","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.jri.2022.103780_bib13","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1093\/humrep\/der092","article-title":"ESHRE consensus on the definition of 'poor response' to ovarian stimulation for in vitro fertilization: the Bologna criteria","volume":"26","author":"Ferraretti","year":"2011","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.jri.2022.103780_bib14","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/S0015-0282(00)00518-5","article-title":"Blastocyst score affects implantation and pregnancy outcome: towards a single blastocyst transfer","volume":"73","author":"Gardner","year":"2000","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jri.2022.103780_bib15","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1111\/1475-6773.12182","article-title":"Methods for constructing and assessing propensity scores","volume":"49","author":"Garrido","year":"2014","journal-title":"Health Serv. Res"},{"key":"10.1016\/j.jri.2022.103780_bib16","article-title":"Cycle regimens for frozen-thawed embryo transfer","volume":"7","author":"Ghobara","year":"2017","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.jri.2022.103780_bib17","first-page":"10","article-title":"The conundrum of poor ovarian response: from diagnosis to treatment","author":"Giannelou","year":"2020","journal-title":"Diagnostics"},{"key":"10.1016\/j.jri.2022.103780_bib18","doi-asserted-by":"crossref","first-page":"2030","DOI":"10.1016\/j.fertnstert.2010.02.022","article-title":"Local injury of the endometrium induces an inflammatory response that promotes successful implantation","volume":"94","author":"Gnainsky","year":"2010","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jri.2022.103780_bib19","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.fertnstert.2004.07.974","article-title":"Effectiveness of two-step (consecutive) embryo transfer in patients who have two embryos on day 2: comparison with cleavage-stage embryo transfer","volume":"83","author":"Goto","year":"2005","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jri.2022.103780_bib20","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1080\/19396368.2016.1199064","article-title":"A modified natural cycle results in higher live birth rate in vitrified-thawed embryo transfer for women with regular menstruation","volume":"62","author":"Guan","year":"2016","journal-title":"Syst. Biol. Reprod. Med"},{"key":"10.1016\/j.jri.2022.103780_bib21","first-page":"580","article-title":"[Economic studies of in vitro fertilization and embryo transfer]","volume":"48","author":"Jing","year":"2019","journal-title":"Zhejiang Da Xue Xue Bao Yi Xue Ban."},{"key":"10.1016\/j.jri.2022.103780_bib22","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1046\/j.1445-5781.2003.00031.x","article-title":"Two-step consecutive transfer of early embryos and blastocysts","volume":"2","author":"Kyono","year":"2003","journal-title":"Reprod. Med Biol."},{"key":"10.1016\/j.jri.2022.103780_bib23","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.fertnstert.2019.02.009","article-title":"What exactly is endometrial receptivity?","volume":"111","author":"Lessey","year":"2019","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jri.2022.103780_bib24","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s12958-022-00899-1","article-title":"Comparisons of benefits and risks of single embryo transfer versus double embryo transfer: a systematic review and meta-analysis","volume":"20","author":"Ma","year":"2022","journal-title":"Reprod. Biol. Endocrinol."},{"key":"10.1016\/j.jri.2022.103780_bib25","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/S1472-6483(10)61442-3","article-title":"Sequential transfer of day 3 embryos and blastocysts after previous IVF failures despite adequate ovarian response","volume":"13","author":"Machtinger","year":"2006","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.jri.2022.103780_bib26","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1002\/uog.17327","article-title":"Blastocyst vs cleavage-stage embryo transfer: systematic review and meta-analysis of reproductive outcomes","volume":"49","author":"Martins","year":"2017","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"10.1016\/j.jri.2022.103780_bib27","first-page":"211","article-title":"New stimulation regimens: endogenous and exogenous progesterone use to block the LH surge during ovarian stimulation for IVF","volume":"23","author":"Massin","year":"2017","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.jri.2022.103780_bib28","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1111\/nyas.14614","article-title":"Evaluating different strategies for poor ovarian response management: a retrospective cohort study and literature review","volume":"1500","author":"Pantou","year":"2021","journal-title":"Ann. N. Y Acad. Sci."},{"key":"10.1016\/j.jri.2022.103780_bib29","first-page":"139","article-title":"Oocyte, embryo and blastocyst cryopreservation in ART: systematic review and meta-analysis comparing slow-freezing versus vitrification to produce evidence for the development of global guidance","volume":"23","author":"Rienzi","year":"2017","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.jri.2022.103780_bib30","first-page":"940","article-title":"Chinese expert consensus on number of embryos transferred","volume":"27","author":"Sun","year":"2018","journal-title":"J. Reprod. Me"},{"key":"10.1016\/j.jri.2022.103780_bib31","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1080\/09513590.2019.1613639","article-title":"The sequential embryo transfer compared to blastocyst embryo transfer in in vitro fertilization (IVF) cycle in patients with the three repeated consecutive IVF. A randomized controlled trial","volume":"35","author":"Tehraninejad","year":"2019","journal-title":"Gynecol. Endocrinol."},{"key":"10.1016\/j.jri.2022.103780_bib32","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.fertnstert.2013.01.087","article-title":"Blastocyst culture and transfer in clinical-assisted reproduction: a committee opinion","volume":"99","author":"The Practice Committees of the American Society for Reproductive Medicine and the Society for Assisted Reproductive Technology","year":"2013","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jri.2022.103780_bib33","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.beem.2019.04.001","article-title":"Single embryo transfer: why and how to identify the embryo with the best developmental potential","volume":"33","author":"Tiitinen","year":"2019","journal-title":"Best. Pr. Res Clin. Endocrinol. Metab."},{"key":"10.1016\/j.jri.2022.103780_bib34","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/352098","article-title":"Management of poor responders in IVF: is there anything new?","volume":"2014","author":"Ubaldi","year":"2014","journal-title":"Biomed. Res Int"},{"key":"10.1016\/j.jri.2022.103780_bib35","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S1472-6483(10)60946-7","article-title":"Management of poor responders in IVF","volume":"10","author":"Ubaldi","year":"2005","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.jri.2022.103780_bib36","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1097\/GCO.0000000000000452","article-title":"What is new in the management of poor ovarian response in IVF?","volume":"30","author":"Vaiarelli","year":"2018","journal-title":"Curr. Opin. Obstet. Gynecol."},{"key":"10.1016\/j.jri.2022.103780_bib37","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1093\/humrep\/deaa093","article-title":"Effects of different cycle regimens for frozen embryo transfer on perinatal outcomes of singletons","volume":"35","author":"Wang","year":"2020","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.jri.2022.103780_bib38","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1002\/jum.14319","article-title":"Association between endometrial\/subendometrial vasculature and embryo transfer outcome: a meta-analysis and subgroup analysis","volume":"37","author":"Wang","year":"2018","journal-title":"J. Ultrasound Med."},{"key":"10.1016\/j.jri.2022.103780_bib39","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1007\/s10815-011-9630-9","article-title":"Effects of cumulus cells removal after 6h co-incubation of gametes on the outcomes of human IVF","volume":"28","author":"Xiong","year":"2011","journal-title":"J. Assist Reprod. Genet"},{"key":"10.1016\/j.jri.2022.103780_bib40","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1017\/S096719941100058X","article-title":"Advantages of the two-step embryo transfer strategy in human IVF\/ICSI cycles","volume":"21","author":"Yazbeck","year":"2013","journal-title":"Zygote"},{"key":"10.1016\/j.jri.2022.103780_bib41","first-page":"112","article-title":"A mild ovarian stimulation strategy in women with poor ovarian reserve undergoing IVF: a multicenter randomized non-inferiority trial","volume":"32","author":"Youssef","year":"2017","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.jri.2022.103780_bib42","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1186\/s12958-021-00824-y","article-title":"Sequential cleavage and blastocyst embryo transfer and IVF outcomes: a systematic review","volume":"19","author":"Zhang","year":"2021","journal-title":"Reprod. Biol. Endocrinol."},{"key":"10.1016\/j.jri.2022.103780_bib43","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1093\/humupd\/dmt036","article-title":"Time of insemination culture and outcomes of in vitro fertilization: a systematic review and meta-analysis","volume":"19","author":"Zhang","year":"2013","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.jri.2022.103780_bib44","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1016\/j.fertnstert.2007.05.064","article-title":"Local injury to the endometrium in controlled ovarian hyperstimulation cycles improves implantation rates","volume":"89","author":"Zhou","year":"2008","journal-title":"Fertil. Steril."}],"container-title":["Journal of Reproductive Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165037822003096?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165037822003096?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T04:33:04Z","timestamp":1759033984000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165037822003096"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2]]},"references-count":44,"alternative-id":["S0165037822003096"],"URL":"https:\/\/doi.org\/10.1016\/j.jri.2022.103780","relation":{},"ISSN":["0165-0378"],"issn-type":[{"value":"0165-0378","type":"print"}],"subject":[],"published":{"date-parts":[[2023,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of sequential cleavage and blastocyst embryo transfer on pregnancy outcomes in patients with poor ovarian response","name":"articletitle","label":"Article Title"},{"value":"Journal of Reproductive Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jri.2022.103780","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"103780"}}