{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T14:31:08Z","timestamp":1793370668118,"version":"4.5.0"},"reference-count":70,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Reproductive Immunology"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1016\/j.jri.2023.104188","type":"journal-article","created":{"date-parts":[[2023,12,28]],"date-time":"2023-12-28T11:48:09Z","timestamp":1703764089000},"page":"104188","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Expanding the role of chromosomal microarray analysis in the evaluation of recurrent pregnancy loss"],"prefix":"10.1016","volume":"161","author":[{"given":"Jasmine","family":"Eliwa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralph S.","family":"Papas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William H.","family":"Kutteh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jri.2023.104188_bib1","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1097\/01.AOG.0000423816.39542.0f","article-title":"Practice bulletin no. 132: antiphospholipid syndrome","volume":"120","year":"2012","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.jri.2023.104188_bib2","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/j.fertnstert.2012.06.048","article-title":"Evaluation and treatment of recurrent pregnancy loss: a committee opinion","volume":"98","year":"2012","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jri.2023.104188_bib3","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.fertnstert.2015.05.028","article-title":"Subclinical hypothyroidism in the infertile female population: a guideline","volume":"104","year":"2015","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jri.2023.104188_bib4","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1093\/humrep\/der024","article-title":"Novel alleles of HLA-DQ and -DR loci show association with recurrent miscarriages among South Indian women","volume":"26","author":"Aruna","year":"2011","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.jri.2023.104188_bib5","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.humimm.2010.11.005","article-title":"Prevalence and qualitative properties of circulating anti-human leukocyte antigen alloantibodies after pregnancy: no association with unexplained recurrent miscarriage","volume":"72","author":"Bartel","year":"2011","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.jri.2023.104188_bib6","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/j.1399-0039.2005.00367.x","article-title":"Association of human leucocyte antigen sharing with recurrent spontaneous abortions","volume":"65","author":"Beydoun","year":"2005","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.jri.2023.104188_bib7","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1038\/gim.0b013e31822e575b","article-title":"Can Factor V Leiden and prothrombin G20210A testing in women with recurrent pregnancy loss result in improved pregnancy outcomes? Results from a targeted evidence-based review","volume":"14","author":"Bradley","year":"2012","journal-title":"Genet. Med."},{"key":"10.1016\/j.jri.2023.104188_bib8","doi-asserted-by":"crossref","DOI":"10.1111\/andr.13395","article-title":"Sperm DNA fragmentation and idiopathic recurrent pregnancy loss: results from a multicenter case-control study","author":"Busnelli","year":"2023","journal-title":"Andrology"},{"key":"10.1016\/j.jri.2023.104188_bib9","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1093\/humupd\/dmr028","article-title":"The prevalence of congenital uterine anomalies in unselected and high-risk populations: a systematic review","volume":"17","author":"Chan","year":"2011","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.jri.2023.104188_bib10","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.semarthrit.2020.03.016","article-title":"Antinuclear antibodies positivity is a risk factor of recurrent pregnancy loss: a meta-analysis","volume":"50","author":"Chen","year":"2020","journal-title":"Semin. Arthritis Rheum."},{"key":"10.1016\/j.jri.2023.104188_bib11","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/S0015-0282(02)03247-8","article-title":"Increased prevalence of insulin resistance in women with a history of recurrent pregnancy loss","volume":"78","author":"Craig","year":"2002","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jri.2023.104188_bib12","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.fertnstert.2019.11.003","article-title":"Subclinical hypothyroidism and thyroid autoimmunity in recurrent pregnancy loss: a systematic review and meta-analysis","volume":"113","author":"Dong","year":"2020","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jri.2023.104188_bib13","doi-asserted-by":"crossref","DOI":"10.1111\/aji.13024","article-title":"Dysregulated uterine natural killer cells and vascular remodeling in women with recurrent pregnancy losses","author":"El-Azzamy","year":"2018","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.jri.2023.104188_bib14","unstructured":"European Society of Human Reproduction and Embryology, 2023. Recurrent Pregnancy Loss Guideline of European Society of Human Reproduction and Embryology."},{"key":"10.1016\/j.jri.2023.104188_bib15","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1093\/humrep\/deq341","article-title":"Killer immunoglobulin-like receptors (KIRs) and HLA-C allorecognition patterns implicative of dominant activation of natural killer cells contribute to recurrent miscarriages","volume":"26","author":"Faridi","year":"2011","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.jri.2023.104188_bib16","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1093\/humrep\/den011","article-title":"Association of maternal killer-cell immunoglobulin-like receptors and parental HLA-C genotypes with recurrent miscarriage","volume":"23","author":"Hiby","year":"2008","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.jri.2023.104188_bib17","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/S0015-0282(98)00164-2","article-title":"Hyperprolactinemic recurrent miscarriage and results of randomized bromocriptine treatment trials","volume":"70","author":"Hirahara","year":"1998","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jri.2023.104188_bib18","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1111\/j.8755-8920.2001.450405.x","article-title":"Blocking antibodies in blood from patients with recurrent spontaneous abortion in relation to pregnancy outcome and intravenous immunoglobulin treatment","volume":"45","author":"Jablonowska","year":"2001","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.jri.2023.104188_bib19","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1016\/j.fertnstert.2013.01.152","article-title":"Effect of prior birth and miscarriage frequency on the prevalence of acquired and congenital uterine anomalies in women with recurrent miscarriage: a cross-sectional study","volume":"99","author":"Jaslow","year":"2013","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jri.2023.104188_bib20","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1016\/j.fertnstert.2009.01.166","article-title":"Diagnostic factors identified in 1020 women with two versus three or more recurrent pregnancy losses","volume":"93","author":"Jaslow","year":"2010","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jri.2023.104188_bib21","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1111\/j.1600-0897.2010.00911.x","article-title":"Thyroid autoimmunity and its association with cellular and humoral immunitiy in women with reporductive failures","volume":"65","author":"Kim","year":"2011","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.jri.2023.104188_bib22","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1111\/aji.12561","article-title":"Maternal HY-restricting HLA class II alleles are associated with poor long-term outcome in recurrent pregnancy loss after a boy","volume":"76","author":"Kolte","year":"2016","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.jri.2023.104188_bib23","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1093\/humrep\/deh200","article-title":"A study of HLA\u2010DR and \u2010DQ alleles in 588 patients and 562 controls confirms that HLA\u2010DRB1*03 is associated with recurrent miscarriage","volume":"19","author":"Kruse","year":"2004","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.jri.2023.104188_bib24","article-title":"The prevalence of mycoplasma and ureaplasma related chronic endometritis in women with a history of recurrent pregnancy loss (RPL)","author":"Kutteh","year":"2016","journal-title":"32nd Annu. Meet. Eur. Soc. Hum. Reprod. Embryol. (ESHRE)"},{"key":"10.1016\/j.jri.2023.104188_bib25","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1055\/s-0035-1552586","article-title":"Novel strategies for the management of recurrent pregnancy loss","volume":"33","author":"Kutteh","year":"2015","journal-title":"Semin. Reprod. Med."},{"key":"10.1016\/j.jri.2023.104188_bib26","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/j.autrev.2016.07.015","article-title":"Humoral and cellular autoimmunity in women with recurrent pregnancy losses and repeated implantation failures: a possiblr role of Vitamin D","volume":"15","author":"Kwak-Kim","year":"2016","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.jri.2023.104188_bib27","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1093\/humrep\/der104","article-title":"Measurements of CD56+ cells in peripheral blood and endometrium by flow cytometry and immunohistochemical staining in situ","volume":"26","author":"Laird","year":"2011","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.jri.2023.104188_bib28","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/aji.12109","article-title":"Beneficial or harmful effect of antipaternal human leukocyte antibodies on pregnancy outcome? A systematic review and meta-analysis","volume":"70","author":"Lashley","year":"2013","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.jri.2023.104188_bib29","first-page":"398","article-title":"Determination of clinical cellular immune markers in women with recurrent pregnancy loss","volume":"70","author":"Lee","year":"2013","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.jri.2023.104188_bib30","article-title":"Male sperm quality and risk of recurrent spontaneous abortion in Chinese couples: a systematic review and meta-analysis","volume":"100","author":"Li","year":"2021","journal-title":"Medicine"},{"key":"10.1016\/j.jri.2023.104188_bib31","doi-asserted-by":"crossref","first-page":"285","DOI":"10.3109\/01443615.2012.759916","article-title":"The relationship between serum prolactin concentration and pregnancy outcome in women with unexplained recurrent miscarriage","volume":"33","author":"Li","year":"2013","journal-title":"J. Obstet. Gynaecol."},{"key":"10.1016\/j.jri.2023.104188_bib32","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1093\/humrep\/deab010","article-title":"Hereditary thrombophilia and recurrent pregnancy loss: a systematic review and meta-analysis","volume":"36","author":"Liu","year":"2021","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.jri.2023.104188_bib33","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/j.fertnstert.2018.01.022","article-title":"Comparison of the prevalence of chronic endometritis as determined by means of different diagnostic methods in women with and without reproductive failure","volume":"109","author":"Liu","year":"2018","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jri.2023.104188_bib34","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1097\/AOG.0b013e31823c0413","article-title":"Prognosis for live birth in women with recurrent miscarriage: what is the best measure of success?","volume":"119","author":"Lund","year":"2012","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.jri.2023.104188_bib35","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1016\/j.fertnstert.2019.06.015","article-title":"Single-nucleotide polymorphism microarray detects molar pregnancies in 3% of miscarriages","volume":"112","author":"Maisenbacher","year":"2019","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jri.2023.104188_bib36","doi-asserted-by":"crossref","DOI":"10.1186\/1756-0500-5-133","article-title":"The comparison of insulin resistance frequency in patients with recurrent early pregnancy loss to normal individuals","volume":"5","author":"Maryam","year":"2012","journal-title":"BMC Res. Notes"},{"key":"10.1016\/j.jri.2023.104188_bib37","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.fertnstert.2019.03.003","article-title":"Sperm DNA fragmentation and recurrent pregnancy loss: a systematic review and meta-analysis","volume":"112","author":"Mcqueen","year":"2019","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jri.2023.104188_bib38","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.humimm.2015.02.004","article-title":"HLA associations and HLA sharing in recurrent miscarriage: a systematic review and meta-analysis","volume":"76","author":"Meuleman","year":"2015","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.jri.2023.104188_bib39","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/j.1538-7836.2006.01753.x","article-title":"International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)","volume":"4","author":"Miyakis","year":"2006","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.jri.2023.104188_bib40","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.fertnstert.2007.04.029","article-title":"A firstborn boy is suggestive of a strong prognostic factor in secondary recurrent miscarriage: a confirmatory study","volume":"89","author":"Nielsen","year":"2008","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jri.2023.104188_bib41","first-page":"2214","article-title":"Association between antiphospholipid antibodies and recurrent fetal loss in women without autoimmune disease: a metaanalysis","volume":"33","author":"Opatrny","year":"2006","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.jri.2023.104188_bib42","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1097\/GCO.0000000000000647","article-title":"A new algorithm for the evaluation of recurrent pregnancy loss redefining unexplained miscarriage: review of current guidelines","volume":"32","author":"Papas","year":"2020","journal-title":"Curr. Opin. Obstet. Gynecol."},{"key":"10.1016\/j.jri.2023.104188_bib43","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1002\/pd.5972","article-title":"Economic impact of using maternal plasma cell-free DNA testing to guide further workup in recurrent pregnancy loss","volume":"41","author":"Peng","year":"2021","journal-title":"Prenat. Diagn."},{"key":"10.1016\/j.jri.2023.104188_bib44","first-page":"329","article-title":"Infectious agents in tissues from spontaneous abortions in the first trimester of pregnancy","volume":"26","author":"Penta","year":"2003","journal-title":"New Microbiol"},{"key":"10.1016\/j.jri.2023.104188_bib45","first-page":"347","article-title":"Plasma TNF-\u03b1 levels are higher in early pregnancy in patients with secondary compared with primary recurrent miscarriage","volume":"70","author":"Piosik","year":"2013","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.jri.2023.104188_bib46","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1093\/humrep\/dey021","article-title":"Recurrent pregnancy loss evaluation combined with 24-chromosome microarray of miscarriage tissue provides a probable or definite cause of pregnancy loss in over 90% of patients","volume":"33","author":"Popescu","year":"2018","journal-title":"Hum. Reprod."},{"issue":"10285","key":"10.1016\/j.jri.2023.104188_bib47","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1016\/S0140-6736(21)00682-6","article-title":"Miscarriage matters: the epidemiological, physical, psychological, and economic costs of early pregnancy loss","volume":"397","author":"Quenby","year":"2021","journal-title":"Lancet"},{"key":"10.1016\/j.jri.2023.104188_bib48","doi-asserted-by":"crossref","DOI":"10.1111\/1471-0528.17515","article-title":"Recurrent MiscarriageGreen-top Guideline No. 17","author":"Regan","year":"2023","journal-title":"BJOG"},{"key":"10.1016\/j.jri.2023.104188_bib49","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/gim.2016.69","article-title":"Comprehensive genetic analysis of pregnancy loss by chromosomal microarrays: outcomes, benefits, and challenges","volume":"19","author":"Sahoo","year":"2017","journal-title":"Genet. Med."},{"key":"10.1016\/j.jri.2023.104188_bib50","doi-asserted-by":"crossref","first-page":"3274","DOI":"10.1093\/humrep\/der293","article-title":"The prevalence and impact of fibroids and their treatment on the outcome of pregnancy in women with recurrent miscarriage","volume":"26","author":"Saravelos","year":"2011","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.jri.2023.104188_bib51","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1016\/j.fertnstert.2015.03.004","article-title":"Reproduction at an advanced maternal age and maternal health","volume":"103","author":"Sauer","year":"2015","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.jri.2023.104188_bib52","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1002\/pd.6244","article-title":"Chromosomal microarray analysis in pregnancy loss: is it time for a consensus approach?","volume":"42","author":"Schilit","year":"2022","journal-title":"Prenat. Diagn."},{"key":"10.1016\/j.jri.2023.104188_bib53","doi-asserted-by":"crossref","DOI":"10.1093\/humrep\/dead093.236","article-title":"O-195Fetal ploidy status in pregnancy loss evaluated by cell-free fetal DNA in maternal blood versus direct sequencing of the pregnancy tissue","volume":"38","author":"Schlaikjaer Hartwig","year":"2023","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.jri.2023.104188_bib54","first-page":"54","article-title":"Diagnosis and treatment of infertility in men: AUA\/ASRM guideline part I","volume":"115","author":"Schlegel","year":"2021","journal-title":"Fertil"},{"key":"10.1016\/j.jri.2023.104188_bib55","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1093\/humupd\/dmt056","article-title":"Natural killer cells in female infertility and recurrent miscarriage: a systematic review and meta-analysis","volume":"20","author":"Seshadri","year":"2014","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.jri.2023.104188_bib56","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1093\/humrep\/17.2.446","article-title":"Cytogenetic analysis of miscarriages from couples with recurrent miscarriage: a case-control study","volume":"17","author":"Stephenson","year":"2002","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.jri.2023.104188_bib57","doi-asserted-by":"crossref","first-page":"d2616","DOI":"10.1136\/bmj.d2616","article-title":"Association between thyroid autoantibodies and miscarriage and preterm birth: meta-analysis of evidence","volume":"342","author":"Thangaratinam","year":"2011","journal-title":"BMJ"},{"key":"10.1016\/j.jri.2023.104188_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.jri.2021.103308","article-title":"HLA-DRB1 polymorphism in recurrent pregnancy loss: new evidence for an association to HLA-DRB1*07","volume":"145","author":"Thomsen","year":"2021","journal-title":"J. Reprod. Immunol."},{"key":"10.1016\/j.jri.2023.104188_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.jri.2022.103794","article-title":"Antinuclear antibodies positivity in women in reproductive age: From infertility to adverse obstetrical outcomes - a meta-analysis","volume":"155","author":"Ticconi","year":"2023","journal-title":"J. Reprod. Immunol."},{"key":"10.1016\/j.jri.2023.104188_bib60","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s00404-023-07001-z","article-title":"Diagnostic factors for recurrent pregnancy loss: an expanded workup","volume":"308","author":"Ticconi","year":"2023","journal-title":"Arch. Gynecol. Obstet."},{"key":"10.1016\/j.jri.2023.104188_bib61","doi-asserted-by":"crossref","DOI":"10.1186\/s12958-019-0514-7","article-title":"The impact of previous live births on peripheral and uterine natural killer cells in patients with recurrent miscarriage","volume":"17","author":"Toth","year":"2019","journal-title":"Reprod. Biol. Endocrinol."},{"key":"10.1016\/j.jri.2023.104188_bib62","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1093\/humupd\/dmz048","article-title":"Recurrent pregnancy loss: diagnostic workup after two or three pregnancy losses? A systematic review of the literature and meta-analysis","volume":"26","author":"Van Dijk","year":"2020","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.jri.2023.104188_bib63","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/S2213-8587(22)00045-6","article-title":"Levothyroxine in euthyroid thyroid peroxidase antibody positive women with recurrent pregnancy loss (T4LIFE trial): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial","volume":"10","author":"Van Dijk","year":"2022","journal-title":"Lancet Diabetes Endocrinol."},{"key":"10.1016\/j.jri.2023.104188_bib64","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1097\/GRF.0000000000000215","article-title":"Immunologic abnormalities, treatments, and recurrent pregnancy loss: what is real and what is not?","volume":"59","author":"Wang","year":"2016","journal-title":"Clin. Obstet. Gynecol."},{"key":"10.1016\/j.jri.2023.104188_bib65","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/S1472-6483(10)60410-5","article-title":"Reappraisal of peripheral NK cells in women with recurrent miscarriage","volume":"17","author":"Wang","year":"2008","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.jri.2023.104188_bib66","doi-asserted-by":"crossref","first-page":"2653","DOI":"10.1093\/humrep\/deh483","article-title":"Maternal KIR repertoire is not associated with recurrent spontaneous abortion","volume":"19","author":"Witt","year":"2004","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.jri.2023.104188_bib67","article-title":"Decreased HLA-C1 alleles in couples of KIR2DL2 positive women with recurrent pregnancy loss","author":"Yang","year":"2020","journal-title":"J. Reprod. Immunol."},{"key":"10.1016\/j.jri.2023.104188_bib68","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24010132","article-title":"The update immune-regulatory role of pro-and anti-inflammatory cytokiines in recurrent pregnancy losses","author":"Yang","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jri.2023.104188_bib69","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1007\/s12026-009-8154-1","article-title":"Immunogenetics and immunology in transplantation","volume":"47","author":"Zachary","year":"2010","journal-title":"Immunol. Res."},{"issue":"6","key":"10.1016\/j.jri.2023.104188_bib70","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1007\/s10815-022-02489-x","article-title":"Can cell-free DNA (cfDNA) testing alleviate psychological distress in early miscarriage? A commentary","volume":"39","author":"Zayyad","year":"2022","journal-title":"J. Assist. Reprod. Genet."}],"container-title":["Journal of Reproductive Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165037823003947?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165037823003947?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T04:35:59Z","timestamp":1759034159000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165037823003947"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":70,"alternative-id":["S0165037823003947"],"URL":"https:\/\/doi.org\/10.1016\/j.jri.2023.104188","relation":{},"ISSN":["0165-0378"],"issn-type":[{"value":"0165-0378","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Expanding the role of chromosomal microarray analysis in the evaluation of recurrent pregnancy loss","name":"articletitle","label":"Article Title"},{"value":"Journal of Reproductive Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jri.2023.104188","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"104188"}}