{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T23:47:15Z","timestamp":1790639235604,"version":"4.1.0"},"reference-count":123,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T00:00:00Z","timestamp":1747958400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["2020-04302"],"award-info":[{"award-number":["2020-04302"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Reproductive Immunology"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.jri.2025.104542","type":"journal-article","created":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T02:26:55Z","timestamp":1747362415000},"page":"104542","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Impact of the maternal microbiome on neonatal immune development"],"prefix":"10.1016","volume":"170","author":[{"given":"Eleni","family":"Dub\u00e9-Zinatelli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwige","family":"Mayotte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luna","family":"Cappelletti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0449-0217","authenticated-orcid":false,"given":"Nafissa","family":"Ismail","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jri.2025.104542_bib1","article-title":"The placenta harbors a unique microbiome","volume":"6","author":"Aagaard","year":"2014","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.jri.2025.104542_bib2","doi-asserted-by":"crossref","first-page":"2269","DOI":"10.1002\/elps.201500011","article-title":"Multiplatform characterization of dynamic changes in breast milk during lactation","volume":"36","author":"Andreas","year":"2015","journal-title":"Electrophoresis"},{"key":"10.1016\/j.jri.2025.104542_bib3","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1038\/s41372-023-01810-5","article-title":"Microbiome dysbiosis: a modifiable state and target to prevent Staphylococcus aureus infections and other diseases in neonates","volume":"44","author":"Aneja","year":"2024","journal-title":"J. Perinatol."},{"key":"10.1016\/j.jri.2025.104542_bib4","doi-asserted-by":"crossref","DOI":"10.1002\/hsr2.1274","article-title":"Global increased cesarean section rates and public health implications: a call to action","volume":"6","author":"Angolile","year":"2023","journal-title":"Health Sci. Rep."},{"key":"10.1016\/j.jri.2025.104542_bib5","doi-asserted-by":"crossref","DOI":"10.1002\/hsr2.1274","article-title":"Global increased cesarean section rates and public health implications: a call to action","volume":"6","author":"Angolile","year":"2023","journal-title":"Health Sci. Rep."},{"key":"10.1016\/j.jri.2025.104542_bib6","doi-asserted-by":"crossref","first-page":"234","DOI":"10.5455\/msm.2023.35.234-243","article-title":"Comparison of gut microbiome in neonates born by caesarean section and vaginal seeding with gut microbiomes of neonates born by caesarean section without vaginal seeding and neonates born by vaginal delivery","volume":"35","author":"Anthoulaki","year":"2023","journal-title":"Mater. Socio"},{"key":"10.1016\/j.jri.2025.104542_bib7","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.amjmed.2014.02.017","article-title":"Fecal microbiota transplantation in the treatment of clostridium difficile infections","volume":"127","author":"Austin","year":"2014","journal-title":"Am. J. Med."},{"key":"10.1016\/j.jri.2025.104542_bib8","first-page":"179","article-title":"Kangaroo care and postpartum depression: the role of oxytocin","volume":"4","author":"Badr","year":"2017","journal-title":"Int. J. Nurs. Sci."},{"key":"10.1016\/j.jri.2025.104542_bib9","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.pcl.2012.10.002","article-title":"Human milk composition","volume":"60","author":"Ballard","year":"2013","journal-title":"Pediatr. Clin. North Am."},{"key":"10.1016\/j.jri.2025.104542_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2021.e07755","article-title":"Factors influencing decision-making to accept elective caesarean section: a descriptive cross-sectional study","volume":"7","author":"Bam","year":"2021","journal-title":"Heliyon"},{"key":"10.1016\/j.jri.2025.104542_bib11","doi-asserted-by":"crossref","DOI":"10.1530\/REP-23-0078","article-title":"The dogma of the sterile uterus revisited: does microbial seeding occur during fetal life in humans and animals?","volume":"167","author":"Banchi","year":"2023","journal-title":"Reproduction"},{"key":"10.1016\/j.jri.2025.104542_bib12","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1089\/bfm.2017.0122","article-title":"The science of breastfeeding and brain development","volume":"12","author":"Belfort","year":"2017","journal-title":"Breastfeed. Med."},{"key":"10.1016\/j.jri.2025.104542_bib13","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/s40168-020-00946-2","article-title":"Lessons learned from the prenatal microbiome controversy","volume":"9","author":"Blaser","year":"2021","journal-title":"Microbiome"},{"key":"10.1016\/j.jri.2025.104542_bib14","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.1002503","article-title":"Fecal transplants: what is being transferred?","volume":"14","author":"Bojanova","year":"2016","journal-title":"PLoS Biol."},{"key":"10.1016\/j.jri.2025.104542_bib15","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.molmed.2014.05.002","article-title":"Microbiota and neurodevelopmental windows: implications for brain disorders","volume":"20","author":"Borre","year":"2014","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.jri.2025.104542_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.mib.2022.102173","article-title":"Mother\u2013infant transmission of human microbiota","volume":"69","author":"Browne","year":"2022","journal-title":"Curr. Opin. Microbiol."},{"key":"10.1016\/j.jri.2025.104542_bib17","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1080\/03004430.2022.2093866","article-title":"The effects of kangaroo care at birth on exclusively breastfeeding, baby\u2019s growth and development according to attachment theory: a randomized controlled trial","volume":"193","author":"\u00c7a\u011fan","year":"2023","journal-title":"Early Child Dev. Care"},{"key":"10.1016\/j.jri.2025.104542_bib18","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1136\/gutjnl-2019-318427","article-title":"Leaky gut: mechanisms, measurement and clinical implications in humans","volume":"68","author":"Camilleri","year":"2019","journal-title":"Gut"},{"key":"10.1016\/j.jri.2025.104542_bib19","doi-asserted-by":"crossref","first-page":"15","DOI":"10.2147\/PHMT.S51869","article-title":"Understanding kangaroo care and its benefits to preterm infants","author":"Campbell-Yeo","year":"2015","journal-title":"Pediatr. Health Med. Ther. 6"},{"key":"10.1016\/j.jri.2025.104542_bib20","first-page":"203","article-title":"The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems","volume":"28","author":"Carabotti","year":"2015","journal-title":"Ann. Gastroenterol."},{"key":"10.1016\/j.jri.2025.104542_bib21","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.jnn.2023.10.012","article-title":"Impact of kangaroo father care in stable very low birth weight infants on father-infant bonding","volume":"30","author":"Chavan","year":"2024","journal-title":"J. Neonatal Nurs."},{"key":"10.1016\/j.jri.2025.104542_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s12276-018-0126-x","article-title":"Mechanisms regulating intestinal barrier integrity and its pathological implications","volume":"50","author":"Chelakkot","year":"2018","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.jri.2025.104542_bib23","doi-asserted-by":"crossref","DOI":"10.14814\/phy2.15469","article-title":"The effects of breastfeeding and formula feeding on the metabolic factors and the expression level of obesity and diabetes-predisposing genes in healthy infants","volume":"10","author":"Cheshmeh","year":"2022","journal-title":"Physiol. Rep."},{"key":"10.1016\/j.jri.2025.104542_bib24","doi-asserted-by":"crossref","DOI":"10.1590\/1518.8345.4466.3446","article-title":"Acquisition of microbiota according to the type of birth: an integrative review","volume":"29","author":"Coelho","year":"2021","journal-title":"Rev. Lat. -Am. Enferm."},{"key":"10.1016\/j.jri.2025.104542_bib25","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.jnn.2017.10.001","article-title":"Does Kangaroo care affect the weight of preterm\/low birth-weight infants in the neonatal setting of a hospital environment?","volume":"24","author":"Cunningham","year":"2018","journal-title":"J. Neonatal Nurs."},{"key":"10.1016\/j.jri.2025.104542_bib26","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.jnn.2021.10.004","article-title":"Neonatal kangaroo care - What we know and how we can improve its practice: an evidence review","volume":"28","author":"Cunningham","year":"2022","journal-title":"J. Neonatal Nurs."},{"key":"10.1016\/j.jri.2025.104542_bib27","first-page":"3173","article-title":"Ethical aspects of fecal microbiota transplantation (FMT)","volume":"19","author":"Daloiso","year":"2015","journal-title":"Eur. Rev. Med. Pharm. Sci."},{"key":"10.1016\/j.jri.2025.104542_bib28","doi-asserted-by":"crossref","first-page":"7993","DOI":"10.3390\/ijerph110807993","article-title":"Antibiotic use and misuse during pregnancy and delivery: benefits and risks","volume":"11","author":"De Tejada","year":"2014","journal-title":"IJERPH"},{"key":"10.1016\/j.jri.2025.104542_bib29","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1097\/MIB.0000000000000750","article-title":"Current understanding of dysbiosis in disease in human and animal models","volume":"22","author":"DeGruttola","year":"2016","journal-title":"Inflamm. Bowel Dis."},{"key":"10.1016\/j.jri.2025.104542_bib30","article-title":"Shaping the gut microbiota by breastfeeding: the gateway to allergy prevention?","volume":"7","author":"van den Elsen","year":"2019","journal-title":"Front. Pedia"},{"key":"10.1016\/j.jri.2025.104542_bib31","series-title":"StatPearls","article-title":"Physiology, Neonatal","author":"Doherty","year":"2024"},{"key":"10.1016\/j.jri.2025.104542_bib32","doi-asserted-by":"crossref","first-page":"11971","DOI":"10.1073\/pnas.1002601107","article-title":"Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns","volume":"107","author":"Dominguez-Bello","year":"2010","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.jri.2025.104542_bib33","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1038\/nm.4039","article-title":"Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer","volume":"22","author":"Dominguez-Bello","year":"2016","journal-title":"Nat. Med."},{"key":"10.1016\/j.jri.2025.104542_bib34","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1038\/nm.4039","article-title":"Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer","volume":"22","author":"Dominguez-Bello","year":"2016","journal-title":"Nat. Med."},{"key":"10.1016\/j.jri.2025.104542_bib35","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2023.1144254","article-title":"Maternal vaginal microbiome composition does not affect development of the infant gut microbiome in early life","volume":"13","author":"Dos Santos","year":"2023","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.jri.2025.104542_bib36","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1097\/ANC.0000000000000218","article-title":"Maternal microbiome and pregnancy outcomes that impact infant health: a review","volume":"15","author":"Dunlop","year":"2015","journal-title":"Adv. Neonatal Care"},{"key":"10.1016\/j.jri.2025.104542_bib37","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1097\/NMC.0000000000000373","article-title":"The maternal infant microbiome: considerations for labor and birth","volume":"42","author":"Dunn","year":"2017","journal-title":"MCN Am. J. Matern. \/Child Nurs."},{"key":"10.1016\/j.jri.2025.104542_bib38","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.3390\/antibiotics12111617","article-title":"The importance of a healthy microbiome in pregnancy and infancy and microbiota treatment to reverse dysbiosis for improved health","volume":"12","author":"DuPont","year":"2023","journal-title":"Antibiotics"},{"key":"10.1016\/j.jri.2025.104542_bib39","doi-asserted-by":"crossref","first-page":"31042","DOI":"10.3402\/fnr.v60.31042","article-title":"A nine-country study of the protein content and amino acid composition of mature human milk","volume":"60","author":"Feng","year":"2016","journal-title":"Food Nutr. Res."},{"key":"10.1016\/j.jri.2025.104542_bib40","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.chom.2018.06.005","article-title":"Mother-to-infant microbial transmission from different body sites shapes the developing infant gut microbiome","volume":"24","author":"Ferretti","year":"2018","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.jri.2025.104542_bib41","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S2213-2600(18)30063-8","article-title":"The global burden of paediatric and neonatal sepsis: a systematic review","volume":"6","author":"Fleischmann-Struzek","year":"2018","journal-title":"Lancet Respir. Med."},{"key":"10.1016\/j.jri.2025.104542_bib42","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1097\/ANC.0000000000000905","article-title":"A systematic review of the effects of skin-to-skin contact on biomarkers of stress in preterm infants and parents","volume":"22","author":"Forde","year":"2022","journal-title":"Adv. Neonatal Care"},{"key":"10.1016\/j.jri.2025.104542_bib43","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1159\/000490847","article-title":"Intervention for dysbiosis in children born by c-section","volume":"73","author":"Francavilla","year":"2018","journal-title":"Ann. Nutr. Metab."},{"key":"10.1016\/j.jri.2025.104542_bib44","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.jnn.2020.12.005","article-title":"Attachment between father and premature baby in kangaroo care in a neonatal unit of a public hospital","volume":"27","author":"Garnica-Torres","year":"2021","journal-title":"J. Neonatal Nurs."},{"key":"10.1016\/j.jri.2025.104542_bib45","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1097\/MOP.0000000000000576","article-title":"The importance of the microbiome in pediatrics and pediatric infectious diseases","volume":"30","author":"Gaufin","year":"2018","journal-title":"Curr. Opin. Pediatr."},{"key":"10.1016\/j.jri.2025.104542_bib46","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1007\/s11892-014-0567-0","article-title":"Probiotics and pregnancy","volume":"15","author":"Gomez Arango","year":"2015","journal-title":"Curr. Diab Rep."},{"key":"10.1016\/j.jri.2025.104542_bib47","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1111\/jmwh.12097","article-title":"Newborn transition","volume":"58","author":"Graves","year":"2013","journal-title":"J. Midwifery Women\u2019S. Health"},{"key":"10.1016\/j.jri.2025.104542_bib48","article-title":"Gut microbiota in obesity and nonalcoholic fatty liver disease","volume":"5","author":"Guo","year":"2021","journal-title":"Surg. Pract. Sci."},{"key":"10.1016\/j.jri.2025.104542_bib49","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1053\/sper.2002.36267","article-title":"Hospital-acquired infections in the neonatal intensive care unit-Klebsiella pneumoniae","volume":"26","author":"Gupta","year":"2002","journal-title":"Semin. Perinatol."},{"key":"10.1016\/j.jri.2025.104542_bib50","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1055\/s-0035-1552941","article-title":"Skin-to-skin care and the development of the preterm infant oral microbiome","volume":"32","author":"Hendricks-Mu\u00f1oz","year":"2015","journal-title":"Am. J. Perinatol."},{"key":"10.1016\/j.jri.2025.104542_bib51","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1111\/apa.15501","article-title":"The impact of caesarean section on the infant gut microbiome","volume":"110","author":"Hoang","year":"2021","journal-title":"Acta Paediatr."},{"key":"10.1016\/j.jri.2025.104542_bib52","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/s12884-016-0876-1","article-title":"The impact of caesarean section on breastfeeding initiation, duration and difficulties in the first four months postpartum","volume":"16","author":"Hobbs","year":"2016","journal-title":"BMC Pregnancy Childbirth"},{"key":"10.1016\/j.jri.2025.104542_bib53","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.chom.2022.02.014","article-title":"Can maternal-child microbial seeding interventions improve the health of infants delivered by Cesarean section?","volume":"30","author":"Hourigan","year":"2022","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.jri.2025.104542_bib54","doi-asserted-by":"crossref","first-page":"442","DOI":"10.3390\/nu3040442","article-title":"Perspectives on immunoglobulins in colostrum and milk","volume":"3","author":"Hurley","year":"2011","journal-title":"Nutrients"},{"key":"10.1016\/j.jri.2025.104542_bib55","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2021.626421","article-title":"The composition of the microbiota in the full-term fetal gut and amniotic fluid: a bovine cesarean section study","volume":"12","author":"Husso","year":"2021","journal-title":"Front. Microbiol"},{"key":"10.1016\/j.jri.2025.104542_bib56","doi-asserted-by":"crossref","first-page":"2028","DOI":"10.1056\/NEJMoa2026486","article-title":"Immediate \u201cKangaroo Mother Care\u201d and survival of infants with low birth weight","volume":"384","author":"Immediate","year":"2021","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jri.2025.104542_bib57","series-title":"The Human Microbiome, Diet, and Health: Workshop Summary","article-title":"Study of the Human Microbiome","year":"2013"},{"key":"10.1016\/j.jri.2025.104542_bib58","doi-asserted-by":"crossref","first-page":"4695","DOI":"10.3390\/ijerph18094695","article-title":"Parent\u2013infant skin-to-skin contact and stress regulation: a systematic review of the literature","volume":"18","author":"Ionio","year":"2021","journal-title":"IJERPH"},{"key":"10.1016\/j.jri.2025.104542_bib59","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-023-41040-5","article-title":"Human milk oligosaccharides modulate the intestinal microbiome of healthy adults","volume":"13","author":"Jacobs","year":"2023","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jri.2025.104542_bib60","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1136\/gutjnl-2012-303249","article-title":"Decreased gut microbiota diversity, delayed bacteroidetes colonisation and reduced Th1 responses in infants delivered by Caesarean section","volume":"63","author":"Jakobsson","year":"2014","journal-title":"Gut"},{"key":"10.1016\/j.jri.2025.104542_bib61","doi-asserted-by":"crossref","first-page":"6289","DOI":"10.1038\/s41467-021-26634-9","article-title":"The composition of human vaginal microbiota transferred at birth affects offspring health in a mouse model","volume":"12","author":"Ja\u0161arevi\u0107","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jri.2025.104542_bib62","doi-asserted-by":"crossref","first-page":"5723","DOI":"10.3390\/ijms24065723","article-title":"Programming factors of neonatal intestinal dysbiosis as a cause of disease","volume":"24","author":"Jovandaric","year":"2023","journal-title":"IJMS"},{"key":"10.1016\/j.jri.2025.104542_bib63","doi-asserted-by":"crossref","first-page":"S98","DOI":"10.1055\/s-0039-3402072","article-title":"Classical cesarean section","volume":"06","author":"Kan","year":"2020","journal-title":"Surg. J. (N. Y)"},{"key":"10.1016\/j.jri.2025.104542_bib64","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1002\/ncp.10490","article-title":"Early-Life gut microbiome\u2014the importance of maternal and infant factors in its establishment","volume":"35","author":"Kapourchali","year":"2020","journal-title":"Nut Clin. Pr."},{"key":"10.1016\/j.jri.2025.104542_bib65","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.tjog.2018.11.002","article-title":"The effect of mother-infant skin to skin contact on success and duration of first breastfeeding: a systematic review and meta-analysis","volume":"58","author":"Karimi","year":"2019","journal-title":"Taiwan. J. Obstet. Gynecol."},{"key":"10.1016\/j.jri.2025.104542_bib66","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.tjog.2018.11.002","article-title":"The effect of mother-infant skin to skin contact on success and duration of first breastfeeding: a systematic review and meta-analysis","volume":"58","author":"Karimi","year":"2019","journal-title":"Taiwan. J. Obstet. Gynecol."},{"issue":"1","key":"10.1016\/j.jri.2025.104542_bib67","doi-asserted-by":"crossref","DOI":"10.1186\/s13006-020-00354-0","article-title":"Nutritional supplements and mother\u2019s milk composition: a systematic review of interventional studies","volume":"16","author":"Keikha","year":"2021","journal-title":"Int Breast J."},{"key":"10.1016\/j.jri.2025.104542_bib68","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1038\/jp.2014.47","article-title":"Impact of lactation stage, gestational age and mode of delivery on breast milk microbiota","volume":"34","author":"Khodayar-Pardo","year":"2014","journal-title":"J. Perinatol."},{"key":"10.1016\/j.jri.2025.104542_bib69","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1159\/000518498","article-title":"Impact of delivery mode on infant gut microbiota","volume":"77","author":"Korpela","year":"2021","journal-title":"Ann. Nutr. Metab."},{"key":"10.1016\/j.jri.2025.104542_bib70","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.cell.2020.08.047","article-title":"Maternal fecal microbiota transplantation in cesarean-born infants rapidly restores normal gut microbial development: a proof-of-concept study","volume":"183","author":"Korpela","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.jri.2025.104542_bib71","doi-asserted-by":"crossref","first-page":"i144","DOI":"10.1093\/ije\/dyq031","article-title":"Kangaroo mother care\u201d to prevent neonatal deaths due to preterm birth complications","volume":"39","author":"Lawn","year":"2010","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.jri.2025.104542_bib72","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.jfma.2023.09.019","article-title":"Link between gut microbiota and neonatal sepsis","volume":"123","author":"Lee","year":"2024","journal-title":"J. Formos. Med. Assoc."},{"key":"10.1016\/j.jri.2025.104542_bib73","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1016\/j.biotechadv.2016.08.003","article-title":"The gut microbiota: a treasure for human health","volume":"34","author":"Li","year":"2016","journal-title":"Biotechnol. Adv."},{"key":"10.1016\/j.jri.2025.104542_bib74","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajogmf.2022.100793","article-title":"Effects of vaginal seeding on gut microbiota, body mass index, and allergy risks in infants born through cesarean delivery: a randomized clinical trial","volume":"5","author":"Liu","year":"2023","journal-title":"Am. J. Obstet. Gynecol. MFM"},{"key":"10.1016\/j.jri.2025.104542_bib75","doi-asserted-by":"crossref","DOI":"10.12707\/RV20033","article-title":"Viv\u00eancias paternas na realiza\u00e7\u00e3o da posi\u00e7\u00e3o canguru com rec\u00e9m-nascidos de baixo peso","volume":"V S\u00e9rie","author":"Lopes","year":"2020","journal-title":"Rev. Enf. Ref."},{"key":"10.1016\/j.jri.2025.104542_bib76","doi-asserted-by":"crossref","first-page":"012","DOI":"10.1055\/s-0035-1554971","article-title":"Klebsiella pneumoniae bacteremia presenting on a neonatal intensive care unit during the first week of life","volume":"10","author":"Malaki","year":"2015","journal-title":"J. Pedia Infect. Dis."},{"key":"10.1016\/j.jri.2025.104542_bib77","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1038\/mi.2011.41","article-title":"Secretory IgA\u2019s complex roles in immunity and mucosal homeostasis in the gut","volume":"4","author":"Mantis","year":"2011","journal-title":"Mucosal Immunol."},{"key":"10.1016\/j.jri.2025.104542_bib78","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1111\/jpc.13676","article-title":"Redox properties of transitional milk from mothers of preterm infants","volume":"54","author":"Mini\u0107","year":"2018","journal-title":"J. Paediatr. Child Health"},{"key":"10.1016\/j.jri.2025.104542_bib79","article-title":"Delivery mode affects stability of early infant gut microbiota","volume":"1","author":"Mitchell","year":"2020","journal-title":"CR Med."},{"key":"10.1016\/j.jri.2025.104542_bib80","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1038\/s41579-020-00460-0","article-title":"The gut microbiota\u2013brain axis in behaviour and brain disorders","volume":"19","author":"Morais","year":"2021","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.jri.2025.104542_bib81","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.3390\/nu13041123","article-title":"Human milk microbiota and oligosaccharides: a glimpse into benefits, diversity, and correlations","volume":"13","author":"Moubareck","year":"2021","journal-title":"Nutrients"},{"key":"10.1016\/j.jri.2025.104542_bib82","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1111\/1471-0528.15979","article-title":"Vaginal seeding\u2019 after a caesarean section provides benefits to newborn children","volume":"127","author":"Mueller","year":"2020","journal-title":"BJOG"},{"key":"10.1016\/j.jri.2025.104542_bib83","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2021.634349","article-title":"Neonatal sepsis: the impact of carbapenem-resistant and hypervirulent klebsiella pneumoniae","volume":"8","author":"Mukherjee","year":"2021","journal-title":"Front. Med."},{"key":"10.1016\/j.jri.2025.104542_bib84","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1007\/s11908-020-00740-z","article-title":"Asymptomatic bacterial vaginosis: to treat or not to treat?","volume":"22","author":"Muzny","year":"2020","journal-title":"Curr. Infect. Dis. Rep."},{"key":"10.1016\/j.jri.2025.104542_bib85","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1159\/000490841","article-title":"Gut microbiota composition in healthy japanese infants and young adults born by c-section","volume":"73","author":"Nagpal","year":"2018","journal-title":"Ann. Nutr. Metab."},{"key":"10.1016\/j.jri.2025.104542_bib86","doi-asserted-by":"crossref","first-page":"194","DOI":"10.5223\/pghn.2022.25.3.194","article-title":"Composition of human breast milk microbiota and its role in children\u2019s health","volume":"25","author":"Notarbartolo","year":"2022","journal-title":"Pedia Gastroenterol. Hepatol. Nutr."},{"key":"10.1016\/j.jri.2025.104542_bib87","doi-asserted-by":"crossref","first-page":"584","DOI":"10.3390\/vaccines9060584","article-title":"Neonatal immune system ontogeny: the role of maternal microbiota and associated factors. How might the non-human primate model enlighten the path?","volume":"9","author":"Nunez","year":"2021","journal-title":"Vaccines"},{"key":"10.1016\/j.jri.2025.104542_bib88","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1097\/PCC.0b013e3182417959","article-title":"Parental involvement and kangaroo care in European neonatal intensive care units: a policy survey in eight countries","volume":"13","author":"Pall\u00e1s-Alonso","year":"2012","journal-title":"Pediatr. Crit. Care Med."},{"key":"10.1016\/j.jri.2025.104542_bib89","doi-asserted-by":"crossref","first-page":"3647","DOI":"10.3390\/nu15163647","article-title":"Development of gut microbiota in the first 1000 days after birth and potential interventions","volume":"15","author":"Pantazi","year":"2023","journal-title":"Nutrients"},{"key":"10.1016\/j.jri.2025.104542_bib90","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1186\/s40168-017-0268-4","article-title":"A critical assessment of the \u201csterile womb\u201d and \u201cin utero colonization\u201d hypotheses: implications for research on the pioneer infant microbiome","volume":"5","author":"Perez-Mu\u00f1oz","year":"2017","journal-title":"Microbiome"},{"key":"10.1016\/j.jri.2025.104542_bib91","doi-asserted-by":"crossref","first-page":"92","DOI":"10.3390\/nu16010092","article-title":"The role of gut microbiota and leaky gut in the pathogenesis of food allergy","volume":"16","author":"Poto","year":"2023","journal-title":"Nutrients"},{"key":"10.1016\/j.jri.2025.104542_bib92","doi-asserted-by":"crossref","first-page":"4997","DOI":"10.1038\/s41467-019-13014-7","article-title":"Impact of delivery mode-associated gut microbiota dynamics on health in the first year of life","volume":"10","author":"Reyman","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jri.2025.104542_bib93","doi-asserted-by":"crossref","first-page":"4997","DOI":"10.1038\/s41467-019-13014-7","article-title":"Impact of delivery mode-associated gut microbiota dynamics on health in the first year of life","volume":"10","author":"Reyman","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jri.2025.104542_bib94","doi-asserted-by":"crossref","first-page":"2122","DOI":"10.3390\/microorganisms9102122","article-title":"From short- to long-term effects of c-section delivery on microbiome establishment and host health","volume":"9","author":"R\u00edos-Covian","year":"2021","journal-title":"Microorganisms"},{"key":"10.1016\/j.jri.2025.104542_bib95","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1038\/s41575-019-0173-3","article-title":"Probiotics and prebiotics in intestinal health and disease: from biology to the clinic","volume":"16","author":"Sanders","year":"2019","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.jri.2025.104542_bib96","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/s41586-019-1560-1","article-title":"Stunted microbiota and opportunistic pathogen colonization in caesarean-section birth","volume":"574","author":"Shao","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.jri.2025.104542_bib97","doi-asserted-by":"crossref","DOI":"10.1016\/j.fbio.2021.100993","article-title":"Recent developments in probiotics: an emphasis on Bifidobacterium","volume":"41","author":"Sharma","year":"2021","journal-title":"Food Biosci."},{"key":"10.1016\/j.jri.2025.104542_bib98","series-title":"StatPearls","article-title":"Neonatal Sepsis","author":"Singh","year":"2025"},{"key":"10.1016\/j.jri.2025.104542_bib99","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.1111\/j.1365-2222.2009.03326.x","article-title":"Influence of early gut microbiota on the maturation of childhood mucosal and systemic immune responses: gut microbiota and immune responses","volume":"39","author":"Sj\u00f6gren","year":"2009","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.jri.2025.104542_bib100","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40733-017-0037-y","article-title":"Microbiome and asthma","volume":"4","author":"Sokolowska","year":"2018","journal-title":"Asthma Res. Pr."},{"key":"10.1016\/j.jri.2025.104542_bib101","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/j.medj.2021.05.003","article-title":"Naturalization of the microbiota developmental trajectory of Cesarean-born neonates after vaginal seeding","volume":"2","author":"Song","year":"2021","journal-title":"Med"},{"key":"10.1016\/j.jri.2025.104542_bib102","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1038\/jp.2015.196","article-title":"Kangaroo care by fathers and mothers: comparison of physiological and stress responses in preterm infants","volume":"36","author":"Srinath","year":"2016","journal-title":"J. Perinatol."},{"key":"10.1016\/j.jri.2025.104542_bib103","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.3389\/fmicb.2019.01124","article-title":"The not-so-sterile womb: evidence that the human fetus is exposed to bacteria prior to birth","volume":"10","author":"Stinson","year":"2019","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.jri.2025.104542_bib104","series-title":"Fertile ground: exploring reproduction in Canada","year":"2014"},{"key":"10.1016\/j.jri.2025.104542_bib105","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1113\/jphysiol.2004.063388","article-title":"Postnatal microbial colonization programs the hypothalamic\u2013pituitary\u2013adrenal system for stress response in mice","volume":"558","author":"Sudo","year":"2004","journal-title":"J. Physiol."},{"key":"10.1016\/j.jri.2025.104542_bib106","series-title":"StatPearls","article-title":"Cesarean Section","author":"Sung","year":"2024"},{"key":"10.1016\/j.jri.2025.104542_bib107","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1038\/nm.4142","article-title":"The microbiome in early life: implications for health outcomes","volume":"22","author":"Tamburini","year":"2016","journal-title":"Nat. Med."},{"key":"10.1016\/j.jri.2025.104542_bib108","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.3390\/nu15061420","article-title":"Effect of maternal diet on maternal milk and breastfed infant gut microbiomes: a scoping review","volume":"15","author":"Taylor","year":"2023","journal-title":"Nutrients"},{"key":"10.1016\/j.jri.2025.104542_bib109","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/S0163-6383(03)00037-7","article-title":"Kangaroo mother care: a method for protecting high-risk low-birth-weight and premature infants against developmental delay","volume":"26","author":"Tessier","year":"2003","journal-title":"Infant Behav. Dev."},{"key":"10.1016\/j.jri.2025.104542_bib110","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2023.1225875","article-title":"The gut microbiota\u2013brain axis in neurological disorder","volume":"17","author":"Ullah","year":"2023","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.jri.2025.104542_bib111","doi-asserted-by":"crossref","first-page":"769","DOI":"10.3945\/jn.110.135657","article-title":"Regulation of tight junction permeability by intestinal bacteria and dietary components1,2","volume":"141","author":"Ulluwishewa","year":"2011","journal-title":"J. Nutr."},{"key":"10.1016\/j.jri.2025.104542_bib112","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1038\/s41372-020-00829-2","article-title":"Neonatal intestinal dysbiosis","volume":"40","author":"Underwood","year":"2020","journal-title":"J. Perinatol."},{"key":"10.1016\/j.jri.2025.104542_bib113","doi-asserted-by":"crossref","first-page":"S38","DOI":"10.1111\/j.1753-4887.2012.00493.x","article-title":"Defining the human microbiome","volume":"70","author":"Ursell","year":"2012","journal-title":"Nutr. Rev."},{"key":"10.1016\/j.jri.2025.104542_bib114","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/S0140-6736(15)01024-7","article-title":"Breastfeeding in the 21st century: epidemiology, mechanisms, and lifelong effect","volume":"387","author":"Victora","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.jri.2025.104542_bib115","doi-asserted-by":"crossref","first-page":"F182","DOI":"10.1136\/archdischild-2011-300097","article-title":"Multi-drug resistant gram negative bacilli causing early neonatal sepsis in India","volume":"97","author":"Viswanathan","year":"2012","journal-title":"Arch. Dis. Child Fetal Neonatal Ed."},{"key":"10.1016\/j.jri.2025.104542_bib116","doi-asserted-by":"crossref","first-page":"6875","DOI":"10.1038\/s41598-022-10869-7","article-title":"Comprehensive human amniotic fluid metagenomics supports the sterile womb hypothesis","volume":"12","author":"Wang","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jri.2025.104542_bib117","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1111\/apa.14754","article-title":"Skin-to-skin contact the first hour after birth, underlying implications and clinical practice","volume":"108","author":"Widstr\u00f6m","year":"2019","journal-title":"Acta Paediatr."},{"key":"10.1016\/j.jri.2025.104542_bib118","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1136\/gutjnl-2022-328970","article-title":"Microbial transmission, colonisation and succession: from pregnancy to infancy","volume":"72","author":"Xiao","year":"2023","journal-title":"Gut"},{"key":"10.1016\/j.jri.2025.104542_bib119","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1097\/NNR.0000000000000133","article-title":"The infant microbiome: implications for infant health and neurocognitive development","volume":"65","author":"Yang","year":"2016","journal-title":"Nurs. Res."},{"key":"10.1016\/j.jri.2025.104542_bib120","article-title":"Inspecting mother-to-infant microbiota transmission: disturbance of strain inheritance by cesarian section","volume":"15","author":"Yang","year":"2024","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.jri.2025.104542_bib121","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.3390\/microorganisms8101587","article-title":"Gut microbiota and immune system interactions","volume":"8","author":"Yoo","year":"2020","journal-title":"Microorganisms"},{"key":"10.1016\/j.jri.2025.104542_bib122","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2019\/1603758","article-title":"Cutting edge: probiotics and fecal microbiota transplantation in immunomodulation","volume":"2019","author":"Zeng","year":"2019","journal-title":"J. Immunol. Res."},{"key":"10.1016\/j.jri.2025.104542_bib123","article-title":"The complex link and disease between the gut microbiome and the immune system in infants","volume":"12","author":"Zhang","year":"2022","journal-title":"Front. Cell. Infect. Microbiol."}],"container-title":["Journal of Reproductive Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165037825001202?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165037825001202?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T08:04:25Z","timestamp":1753430665000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165037825001202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":123,"alternative-id":["S0165037825001202"],"URL":"https:\/\/doi.org\/10.1016\/j.jri.2025.104542","relation":{},"ISSN":["0165-0378"],"issn-type":[{"value":"0165-0378","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of the maternal microbiome on neonatal immune development","name":"articletitle","label":"Article Title"},{"value":"Journal of Reproductive Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jri.2025.104542","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"104542"}}