{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:59:25Z","timestamp":1792681165949,"version":"4.5.0"},"reference-count":220,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100016286","name":"Urmia University of Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100016286","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Reproductive Immunology"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.jri.2025.104831","type":"journal-article","created":{"date-parts":[[2026,1,3]],"date-time":"2026-01-03T16:19:55Z","timestamp":1767457195000},"page":"104831","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["The role of extracellular vesicles in animal reproduction"],"prefix":"10.1016","volume":"173","author":[{"given":"Asal","family":"Golchin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amirhossein","family":"Faghih Ojaroodi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siamak","family":"Rezaeiani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hojat","family":"Ghasemnejad-Berenji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9659-7491","authenticated-orcid":false,"given":"Mortaza","family":"Taheri-Anganeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib1","doi-asserted-by":"crossref","first-page":"R1","DOI":"10.1530\/REP-13-0358","article-title":"Prostasomes: extracellular vesicles from the prostate","volume":"147","author":"Aalberts","year":"2014","journal-title":"Reproduction"},{"key":"10.1016\/j.jri.2025.104831_bib2","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.theriogenology.2020.05.043","article-title":"Porcine oviductal extracellular vesicles interact with gametes and regulate sperm motility and survival","volume":"155","author":"Alc\u00e2ntara-Neto","year":"2020","journal-title":"Theriogenology"},{"issue":"9","key":"10.1016\/j.jri.2025.104831_bib3","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.3390\/biom12091300","article-title":"Oviductal extracellular vesicles enhance porcine in vitro embryo development by modulating the embryonic transcriptome","volume":"12","author":"de Alc\u00e2ntara-Neto","year":"2022","journal-title":"Biomolecules"},{"issue":"10","key":"10.1016\/j.jri.2025.104831_bib4","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1016\/j.biocel.2010.06.001","article-title":"The roles of cellular reactive oxygen species, oxidative stress and antioxidants in pregnancy outcomes","volume":"42","author":"Al-Gubory","year":"2010","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.jri.2025.104831_bib5","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.theriogenology.2020.01.077","article-title":"Extracellular vesicles: multi-signal messengers in the gametes\/embryo-oviduct cross-talk","volume":"150","author":"Almi\u00f1ana","year":"2020","journal-title":"Theriogenology"},{"issue":"3","key":"10.1016\/j.jri.2025.104831_bib6","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1530\/REP-17-0054","article-title":"Oviduct extracellular vesicles protein content and their role during oviduct\u2013embryo cross-talk","volume":"154","author":"Almi\u00f1ana","year":"2017","journal-title":"Reproduction"},{"issue":"4","key":"10.1016\/j.jri.2025.104831_bib7","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1038\/nbt.1807","article-title":"Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes","volume":"29","author":"Alvarez-Erviti","year":"2011","journal-title":"Nat. Biotechnol."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib8","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-14264-5","article-title":"A total transcriptome profiling method for plasma-derived extracellular vesicles: applications for liquid biopsies","volume":"7","author":"Amorim","year":"2017","journal-title":"Sci. Rep."},{"issue":"6","key":"10.1016\/j.jri.2025.104831_bib9","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1111\/rda.13021","article-title":"Cellular and extracellular vesicular origins of miRNAs within the bovine ovarian follicle","volume":"52","author":"Andrade","year":"2017","journal-title":"Reprod. Domest. Anim."},{"issue":"11","key":"10.1016\/j.jri.2025.104831_bib10","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1093\/molehr\/gav049","article-title":"Plasma membrane Ca2+-ATPase 4: interaction with constitutive nitric oxide synthases in human sperm and prostasomes which carry Ca2+\/CaM-dependent serine kinase","volume":"21","author":"Andrews","year":"2015","journal-title":"Mol. Hum. Reprod."},{"issue":"4","key":"10.1016\/j.jri.2025.104831_bib11","first-page":"158","article-title":"Pharmacology of free radicals and the impact of reactive oxygen species on the testis","volume":"14","author":"Aprioku","year":"2013","journal-title":"J. Reprod. Infertil."},{"issue":"2","key":"10.1016\/j.jri.2025.104831_bib12","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1006\/abbi.1998.0876","article-title":"Fatty acid pattern of human prostasome lipid","volume":"358","author":"Arienti","year":"1998","journal-title":"Arch. Biochem. Biophys."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib13","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/j.1768-322X.1999.tb01083.x","article-title":"The motility of human spermatozoa as influenced by prostasomes at various pH levels","volume":"91","author":"Arienti","year":"1999","journal-title":"Biol. Cell"},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib14","doi-asserted-by":"crossref","first-page":"31","DOI":"10.21451\/1984-3143-AR2018-0101","article-title":"Extracellular vesicles and its advances in female reproduction","volume":"16","author":"\u00c1vila","year":"2019","journal-title":"Anim. Reprod."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib15","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1016\/j.bbrc.2017.11.100","article-title":"Induction of immune-related gene expression by seminal exosomes in the porcine endometrium","volume":"495","author":"Bai","year":"2018","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"7","key":"10.1016\/j.jri.2025.104831_bib16","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1038\/ncb2502","article-title":"Syndecan\u2013syntenin\u2013ALIX regulates the biogenesis of exosomes","volume":"14","author":"Baietti","year":"2012","journal-title":"Nat. Cell Biol."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib17","doi-asserted-by":"crossref","DOI":"10.1590\/1984-3143-ar2022-0015","article-title":"The role of the oviduct and extracellular vesicles during early embryo development in bovine","volume":"19","author":"Bastos","year":"2022","journal-title":"Anim. Reprod."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib18","doi-asserted-by":"crossref","DOI":"10.1080\/20013078.2017.1340746","article-title":"Extracellular vesicles released following heat stress induce bystander effect in unstressed populations","volume":"6","author":"Bewicke-Copley","year":"2017","journal-title":"J. Extracell. Vesicles"},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib19","doi-asserted-by":"crossref","first-page":"4379","DOI":"10.1038\/s41467-018-06881-z","article-title":"Testicular endothelial cells are a critical population in the germline stem cell niche","volume":"9","author":"Bhang","year":"2018","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib20","doi-asserted-by":"crossref","DOI":"10.1038\/srep40476","article-title":"Extracellular vesicle mediated intercellular communication at the porcine maternal-fetal interface: a new paradigm for conceptus-endometrial cross-talk","volume":"7","author":"Bidarimath","year":"2017","journal-title":"Sci. Rep."},{"issue":"3","key":"10.1016\/j.jri.2025.104831_bib21","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1093\/humupd\/dmi052","article-title":"Prostasomes--their effects on human male reproduction and fertility","volume":"12","author":"Burden","year":"2006","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.jri.2025.104831_bib22","doi-asserted-by":"crossref","first-page":"8847","DOI":"10.2147\/IJN.S225453","article-title":"Extracellular vesicles as nanomedicine: hopes and hurdles in clinical translation","author":"Burnouf","year":"2019","journal-title":"Int. J. Nanomed."},{"issue":"3","key":"10.1016\/j.jri.2025.104831_bib23","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0090913","article-title":"Extracellular Vesicles in Luminal Fluid of the Ovine Uterus","volume":"9","author":"Burns","year":"2014","journal-title":"Plos One"},{"issue":"3","key":"10.1016\/j.jri.2025.104831_bib24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1095\/biolreprod.115.134973","article-title":"Extracellular vesicles originate from the conceptus and uterus during early pregnancy in sheep","volume":"94","author":"Burns","year":"2016","journal-title":"Biol. Reprod."},{"issue":"9","key":"10.1016\/j.jri.2025.104831_bib25","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1096\/fba.2021-00045","article-title":"The role of extracellular vesicles in the physiological and pathological regulation of the blood\u2013brain barrier","volume":"3","author":"Busatto","year":"2021","journal-title":"FASEB BioAdvances"},{"issue":"12","key":"10.1016\/j.jri.2025.104831_bib26","doi-asserted-by":"crossref","first-page":"3876","DOI":"10.1002\/jcp.24099","article-title":"Bovine sperm raft membrane associated glioma pathogenesis-related 1-like protein 1 (GliPr1L1) is modified during the epididymal transit and is potentially involved in sperm binding to the zona pellucida","volume":"227","author":"Caballero","year":"2012","journal-title":"J. Cell. Physiol."},{"issue":"6","key":"10.1016\/j.jri.2025.104831_bib27","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0065364","article-title":"CD9-positive microvesicles mediate the transfer of molecules to bovine spermatozoa during epididymal maturation","volume":"8","author":"Caballero","year":"2013","journal-title":"PloS One"},{"issue":"19","key":"10.1016\/j.jri.2025.104831_bib28","doi-asserted-by":"crossref","first-page":"7022","DOI":"10.3390\/ijms21197022","article-title":"Exosome composition and seminal plasma proteome: a promising source of biomarkers of male infertility","volume":"21","author":"Candenas","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"11","key":"10.1016\/j.jri.2025.104831_bib29","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.3390\/biom10111510","article-title":"The biological function of extracellular vesicles during fertilization, early embryo\u2014maternal crosstalk and their involvement in reproduction: review and overview","volume":"10","author":"Capra","year":"2020","journal-title":"Biomolecules"},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib30","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1001\/jama.2021.4788","article-title":"Diagnosis and management of infertility: a review","volume":"326","author":"Carson","year":"2021","journal-title":"Jama"},{"key":"10.1016\/j.jri.2025.104831_bib31","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.3389\/fimmu.2018.01486","article-title":"Apoptotic cell-derived extracellular vesicles: more than just debris","volume":"9","author":"Caruso","year":"2018","journal-title":"Front. Immunol."},{"issue":"6","key":"10.1016\/j.jri.2025.104831_bib32","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1161\/HYPERTENSIONAHA.118.11706","article-title":"Exosomes from women with preeclampsia induced vascular dysfunction by delivering sFlt (soluble Fms-like tyrosine kinase)-1 and sEng (soluble endoglin) to endothelial cells","volume":"72","author":"Chang","year":"2018","journal-title":"Hypertension"},{"issue":"7718","key":"10.1016\/j.jri.2025.104831_bib33","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1038\/s41586-018-0392-8","article-title":"Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response","volume":"560","author":"Chen","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.jri.2025.104831_bib34","article-title":"The role of extracellular vesicles in embryo implantation","volume":"13","author":"Chen","year":"2022","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.jri.2025.104831_bib35","article-title":"The role of extracellular vesicles in embryo implantation","volume":"13","author":"Chen","year":"2022","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.jri.2025.104831_bib36","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.3389\/fimmu.2018.01534","article-title":"Therapeutic prospects of extracellular vesicles in cancer treatment","volume":"9","author":"Chulpanova","year":"2018","journal-title":"Front. Immunol."},{"issue":"16","key":"10.1016\/j.jri.2025.104831_bib37","doi-asserted-by":"crossref","first-page":"3631","DOI":"10.1242\/jcs.02494","article-title":"Induction of heat shock proteins in B-cell exosomes","volume":"118","author":"Clayton","year":"2005","journal-title":"J. Cell Sci."},{"issue":"6","key":"10.1016\/j.jri.2025.104831_bib38","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.tcb.2015.01.004","article-title":"Ectosomes and exosomes: shedding the confusion between extracellular vesicles","volume":"25","author":"Cocucci","year":"2015","journal-title":"Trends Cell Biol."},{"issue":"3","key":"10.1016\/j.jri.2025.104831_bib39","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/s12192-010-0236-4","article-title":"Extracellular heat shock proteins, cellular export vesicles, and the Stress Observation System: a form of communication during injury, infection, and cell damage","volume":"16","author":"De Maio","year":"2011","journal-title":"Cell Stress Chaperon."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib40","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms11958","article-title":"Microvesicles provide a mechanism for intercellular communication by embryonic stem cells during embryo implantation","volume":"7","author":"Desrochers","year":"2016","journal-title":"Nat. Commun."},{"issue":"2","key":"10.1016\/j.jri.2025.104831_bib41","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1530\/REP-20-0423","article-title":"Palmitoylated GLB1L4 transfers via exosomes to maintain sperm function in rat epididymis","volume":"161","author":"Dong","year":"2021","journal-title":"Reproduction"},{"issue":"5","key":"10.1016\/j.jri.2025.104831_bib42","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/nrd3978","article-title":"Extracellular vesicles: biology and emerging therapeutic opportunities","volume":"12","author":"El Andaloussi","year":"2013","journal-title":"Nat. Rev. Drug Discov."},{"issue":"12","key":"10.1016\/j.jri.2025.104831_bib43","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0015353","article-title":"Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA","volume":"5","author":"Eldh","year":"2010","journal-title":"PloS One"},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib44","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1186\/s13287-022-02806-2","article-title":"Engineering strategies for customizing extracellular vesicle uptake in a therapeutic context","volume":"13","author":"Esmaeili","year":"2022","journal-title":"Stem Cell Res. Ther."},{"issue":"23","key":"10.1016\/j.jri.2025.104831_bib45","doi-asserted-by":"crossref","DOI":"10.1002\/pmic.201800423","article-title":"Human endometrial extracellular vesicles functionally prepare human trophectoderm model for implantation: understanding bidirectional maternal-embryo communication","volume":"19","author":"Evans","year":"2019","journal-title":"Proteomics"},{"issue":"12","key":"10.1016\/j.jri.2025.104831_bib46","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1016\/j.bbamcr.2009.09.011","article-title":"TI-VAMP\/VAMP7 and VAMP3\/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy\/multivesicular body pathways","volume":"1793","author":"Fader","year":"2009","journal-title":"Biochimica et Biophysica Acta (BBA)Molecular Cell Research"},{"issue":"12","key":"10.1016\/j.jri.2025.104831_bib47","doi-asserted-by":"crossref","DOI":"10.1002\/jev2.12153","article-title":"Neddylation of Coro1a determines the fate of multivesicular bodies and biogenesis of extracellular vesicles","volume":"10","author":"Fei","year":"2021","journal-title":"J. Extracell. Vesicles"},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib48","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-34409-4","article-title":"Murine Oviductosomes (OVS) microRNA profiling during the estrous cycle: delivery of OVS-borne microRNAs to sperm where miR-34c-5p localizes at the centrosome","volume":"8","author":"Fereshteh","year":"2018","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib49","doi-asserted-by":"crossref","first-page":"9484","DOI":"10.1038\/s41598-019-45857-x","article-title":"Oviductal extracellular vesicles interact with the spermatozoon's head and mid-piece and improves its motility and fertilizing ability in the domestic cat","volume":"9","author":"Ferraz","year":"2019","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib50","doi-asserted-by":"crossref","first-page":"9484","DOI":"10.1038\/s41598-019-45857-x","article-title":"Oviductal extracellular vesicles interact with the spermatozoon\u2019s head and mid-piece and improves its motility and fertilizing ability in the domestic cat","volume":"9","author":"Ferraz","year":"2019","journal-title":"Sci. Rep."},{"issue":"12","key":"10.1016\/j.jri.2025.104831_bib51","first-page":"833","article-title":"Uterosome-like vesicles prompt human sperm fertilizing capability","volume":"22","author":"Franchi","year":"2016","journal-title":"Mol. Hum. Reprod."},{"issue":"3","key":"10.1016\/j.jri.2025.104831_bib52","doi-asserted-by":"crossref","first-page":"388","DOI":"10.3390\/biom11030388","article-title":"Circulating extracellular vesicles as biomarkers and drug delivery vehicles in cardiovascular diseases","volume":"11","author":"de Freitas","year":"2021","journal-title":"Biomolecules"},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib53","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1002\/mrd.1013","article-title":"Prostasome-like particles are involved in the transfer of P25b from the bovine epididymal fluid to the sperm surface","volume":"59","author":"Frenette","year":"2001","journal-title":"Mol. Reprod. Devel. Incorporating Gamete Res."},{"issue":"5","key":"10.1016\/j.jri.2025.104831_bib54","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1095\/biolreprod.103.019216","article-title":"Aldose reductase and macrophage migration inhibitory factor are associated with epididymosomes and spermatozoa in the bovine epididymis","volume":"69","author":"Frenette","year":"2003","journal-title":"Biol. Reprod."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib55","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/1477-7827-3-43","article-title":"Fundamental roles of reactive oxygen species and protective mechanisms in the female reproductive system","volume":"3","author":"Fujii","year":"2005","journal-title":"Reprod. Biol. Endocrinol."},{"issue":"12","key":"10.1016\/j.jri.2025.104831_bib56","doi-asserted-by":"crossref","first-page":"5238","DOI":"10.1158\/0008-5472.CAN-04-3804","article-title":"Heat shock protein 70 surface-positive tumor exosomes stimulate migratory and cytolytic activity of natural killer cells","volume":"65","author":"Gastpar","year":"2005","journal-title":"Cancer Res."},{"key":"10.1016\/j.jri.2025.104831_bib57","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2020.602043","article-title":"Extracellular vesicles as mediators of environmental and metabolic stress coping mechanisms during mammalian follicular development","volume":"7","author":"Gebremedhn","year":"2020","journal-title":"Front. Vet. Sci."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib58","doi-asserted-by":"crossref","first-page":"3477","DOI":"10.1038\/ncomms4477","article-title":"Syntenin-ALIX exosome biogenesis and budding into multivesicular bodies are controlled by ARF6 and PLD2","volume":"5","author":"Ghossoub","year":"2014","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib59","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/cei.13304","article-title":"Embryonic extracellular vesicles as informers to the immune cells at the maternal\u2013fetal interface","volume":"198","author":"Giacomini","year":"2019","journal-title":"Clin. Exp. Immunol."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib60","doi-asserted-by":"crossref","DOI":"10.1186\/s12958-021-00801-5","article-title":"Trophoblast derived extracellular vesicles specifically alter the transcriptome of endometrial cells and may constitute a critical component of embryo-maternal communication","volume":"19","author":"Godakumara","year":"2021","journal-title":"Reprod. Biol. Endocrinol."},{"issue":"7","key":"10.1016\/j.jri.2025.104831_bib61","doi-asserted-by":"crossref","first-page":"6811","DOI":"10.3390\/ijms24076811","article-title":"Rhythm of the first language: dynamics of extracellular vesicle-based embryo\u2013maternal communication in the pre-implantation microenvironment","volume":"24","author":"Godakumara","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jri.2025.104831_bib62","doi-asserted-by":"crossref","first-page":"2663","DOI":"10.3389\/fimmu.2019.02663","article-title":"Therapeutic application of mesenchymal stem cells derived extracellular vesicles for immunomodulation","volume":"10","author":"Gomzikova","year":"2019","journal-title":"Front. Immunol."},{"issue":"5-6","key":"10.1016\/j.jri.2025.104831_bib63","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1515\/hsz-2016-0274","article-title":"Mechanisms of action of Rab proteins, key regulators of intracellular vesicular transport","volume":"398","author":"Goody","year":"2017","journal-title":"Biol. Chem."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib64","doi-asserted-by":"crossref","DOI":"10.3402\/jev.v2i0.20389","article-title":"As we wait: coping with an imperfect nomenclature for extracellular vesicles","volume":"2","author":"Gould","year":"2013","journal-title":"J. Extracell. Vesicles"},{"issue":"6","key":"10.1016\/j.jri.2025.104831_bib65","doi-asserted-by":"crossref","first-page":"836","DOI":"10.3390\/biom15060836","article-title":"Unraveling the multi-omic landscape of extracellular vesicles in human seminal plasma","volume":"15","author":"Governini","year":"2025","journal-title":"Biomolecules"},{"issue":"2","key":"10.1016\/j.jri.2025.104831_bib66","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1095\/biolreprod.115.134890","article-title":"Human endometrial exosomes contain hormone-specific cargo modulating trophoblast adhesive capacity: insights into endometrial-embryo interactions","volume":"94","author":"Greening","year":"2016","journal-title":"Biol. Reprod."},{"issue":"10","key":"10.1016\/j.jri.2025.104831_bib67","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1038\/ncb2574","article-title":"Active Wnt proteins are secreted on exosomes","volume":"14","author":"Gross","year":"2012","journal-title":"Nat. Cell Biol."},{"issue":"2","key":"10.1016\/j.jri.2025.104831_bib68","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1093\/humupd\/7.2.175","article-title":"Menezo Y. Oxidative stress and protection against reactive oxygen species in the pre-implantation embryo and its surroundings","volume":"7","author":"Guerin","year":"2001","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.jri.2025.104831_bib69","doi-asserted-by":"crossref","first-page":"3357","DOI":"10.2147\/IJN.S310357","article-title":"Biogenesis, membrane trafficking, functions, and next generation nanotherapeutics medicine of extracellular vesicles","author":"Gurunathan","year":"2021","journal-title":"Int. J. Nanomed."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib70","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1186\/s40104-022-00715-1","article-title":"The role of extracellular vesicles in animal reproduction and diseases","volume":"13","author":"Gurunathan","year":"2022","journal-title":"J. Anim. Sci. Biotechnol."},{"issue":"7","key":"10.1016\/j.jri.2025.104831_bib71","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1093\/molehr\/gaaa034","article-title":"Exosomes and soluble secretome from hormone-treated endometrial epithelial cells direct embryo implantation","volume":"26","author":"Gurung","year":"2020","journal-title":"Mol. Hum. Reprod."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib72","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/s12964-021-00730-1","article-title":"The exosome journey: from biogenesis to uptake and intracellular signalling","volume":"19","author":"Gurung","year":"2021","journal-title":"Cell Commun. Signal."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib73","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/s12943-019-0980-8","article-title":"Extracellular vesicles in the tumor microenvironment: old stories, but new tales","volume":"18","author":"Han","year":"2019","journal-title":"Mol. Cancer"},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib74","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1186\/s12943-022-01671-0","article-title":"Exosome biogenesis: machinery, regulation, and therapeutic implications in cancer","volume":"21","author":"Han","year":"2022","journal-title":"Mol. Cancer"},{"issue":"7","key":"10.1016\/j.jri.2025.104831_bib75","first-page":"518","article-title":"Progress in understanding the functional roles of extracellular vesicles in reproduction","volume":"33","author":"Han","year":"2020","journal-title":"Biomed. Environ. Sci."},{"issue":"21","key":"10.1016\/j.jri.2025.104831_bib76","doi-asserted-by":"crossref","first-page":"8280","DOI":"10.3390\/ijms21218280","article-title":"Extracellular vesicles and the oviduct function","volume":"21","author":"Harris","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"5","key":"10.1016\/j.jri.2025.104831_bib77","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1007\/s00018-018-2965-y","article-title":"Transition of inner cell mass to embryonic stem cells: mechanisms, facts, and hypotheses","volume":"76","author":"Hassani","year":"2019","journal-title":"Cell. Mol. Life Sci."},{"issue":"3","key":"10.1016\/j.jri.2025.104831_bib78","doi-asserted-by":"crossref","first-page":"e1071","DOI":"10.1210\/clinem\/dgaa839","article-title":"Update on PCOS: consequences, challenges, and guiding treatment","volume":"106","author":"Hoeger","year":"2021","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"2","key":"10.1016\/j.jri.2025.104831_bib79","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1083\/jcb.200911018","article-title":"Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A\u2013C","volume":"189","author":"Hsu","year":"2010","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.jri.2025.104831_bib80","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.118960","article-title":"Perfluorooctane sulfonate induces suppression of testosterone biosynthesis via Sertoli cell-derived exosomal\/miR-9-3p downregulating StAR expression in Leydig cells","volume":"301","author":"Huang","year":"2022","journal-title":"Environ. Pollut."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib81","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1152\/physrev.00059.2009","article-title":"Role of Rab GTPases in membrane traffic and cell physiology","volume":"91","author":"Hutagalung","year":"2011","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.jri.2025.104831_bib82","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.gde.2017.06.012","article-title":"Acquisition of the pluripotent and trophectoderm states in the embryo and during somatic nuclear reprogramming","volume":"46","author":"Jaber","year":"2017","journal-title":"Curr. Opin. Genet. Dev."},{"issue":"15","key":"10.1016\/j.jri.2025.104831_bib83","doi-asserted-by":"crossref","first-page":"5377","DOI":"10.3390\/ijms21155377","article-title":"The role of the epididymis and the contribution of epididymosomes to mammalian reproduction","volume":"21","author":"James","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib84","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s40659-022-00405-2","article-title":"Extracellular signals regulate the biogenesis of extracellular vesicles","volume":"55","author":"Jin","year":"2022","journal-title":"Biol. Res."},{"issue":"7","key":"10.1016\/j.jri.2025.104831_bib85","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1038\/nrm.2016.25","article-title":"Metabolomics: beyond biomarkers and towards mechanisms","volume":"17","author":"Johnson","year":"2016","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"4","key":"10.1016\/j.jri.2025.104831_bib86","doi-asserted-by":"crossref","first-page":"4444","DOI":"10.1021\/acsnano.9b10033","article-title":"Endocytosis of extracellular vesicles and release of their cargo from endosomes","volume":"14","author":"Joshi","year":"2020","journal-title":"ACS Nano"},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib87","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-70584-z","article-title":"Cytokine profiling in serum-derived exosomes isolated by different methods","volume":"10","author":"Jung","year":"2020","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.jri.2025.104831_bib88","doi-asserted-by":"crossref","first-page":"170","DOI":"10.3390\/ijms17020170","article-title":"Focus on extracellular vesicles: introducing the next small big thing","volume":"17","author":"Kalra","year":"2016","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib89","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1210\/clinem\/dgz019","article-title":"Uterine fluid proteins for minimally invasive assessment of endometrial receptivity","volume":"105","author":"Kasvandik","year":"2020","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib90","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0300-483X(00)00231-6","article-title":"The Haber\u2013Weiss reaction and mechanisms of toxicity","volume":"149","author":"Kehrer","year":"2000","journal-title":"Toxicology"},{"issue":"06","key":"10.1016\/j.jri.2025.104831_bib91","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1055\/s-0041-111173","article-title":"MicroRNA profile of granulosa cells after ovarian stimulation differs according to maturity of retrieved oocytes","volume":"76","author":"Kim","year":"2016","journal-title":"Geburtshilfe und Frauenheilkd."},{"issue":"2","key":"10.1016\/j.jri.2025.104831_bib92","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1530\/rep.1.01074","article-title":"TGF-\u03b2 superfamily members and ovarian follicle development","volume":"132","author":"Knight","year":"2006","journal-title":"Reproduction"},{"issue":"Pt 2","key":"10.1016\/j.jri.2025.104831_bib93","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1042\/bj2980249","article-title":"Nitric oxide synthases in mammals","volume":"298","author":"Knowles","year":"1994","journal-title":"Biochem. J."},{"issue":"3","key":"10.1016\/j.jri.2025.104831_bib94","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/(SICI)1097-0045(20000515)43:3<169::AID-PROS2>3.0.CO;2-D","article-title":"Prostasomes: current concepts","volume":"43","author":"Kravets","year":"2000","journal-title":"Prostate"},{"issue":"3","key":"10.1016\/j.jri.2025.104831_bib95","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/(SICI)1097-0045(20000515)43:3<169::AID-PROS2>3.0.CO;2-D","article-title":"Prostasomes: current concepts","volume":"43","author":"Kravets","year":"2000","journal-title":"Prostate"},{"issue":"12","key":"10.1016\/j.jri.2025.104831_bib96","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1016\/j.placenta.2012.10.005","article-title":"Immunomodulatory molecules are released from the first trimester and term placenta via exosomes","volume":"33","author":"Kshirsagar","year":"2012","journal-title":"Placenta"},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib97","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1016\/j.bbrc.2017.11.176","article-title":"Intrauterine exosomes are required for bovine conceptus implantation","volume":"495","author":"Kusama","year":"2018","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"2","key":"10.1016\/j.jri.2025.104831_bib98","doi-asserted-by":"crossref","first-page":"273","DOI":"10.3390\/pr9020273","article-title":"Extracellular vesicle transportation and uptake by recipient cells: a critical process to regulate human diseases","volume":"9","author":"Kwok","year":"2021","journal-title":"Processes"},{"issue":"24","key":"10.1016\/j.jri.2025.104831_bib99","doi-asserted-by":"crossref","first-page":"23349","DOI":"10.1074\/jbc.M502017200","article-title":"Exosome-dependent trafficking of HSP70: a novel secretory pathway for cellular stress proteins","volume":"280","author":"Lancaster","year":"2005","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.jri.2025.104831_bib100","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1530\/REP-17-0117","article-title":"Oviductal microvesicles and their effect on in vitro maturation of canine oocytes","volume":"154","author":"Lange-Consiglio","year":"2017","journal-title":"Reproduction"},{"key":"10.1016\/j.jri.2025.104831_bib101","doi-asserted-by":"crossref","first-page":"347","DOI":"10.3389\/fvets.2020.00347","article-title":"Case report: use of amniotic microvesicles for regenerative medicine treatment of a mare with chronic endometritis","volume":"7","author":"Lange-Consiglio","year":"2020","journal-title":"Front. Vet. Sci."},{"issue":"11","key":"10.1016\/j.jri.2025.104831_bib102","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/j.tcb.2018.06.007","article-title":"Rab GTPase function in endosome and lysosome biogenesis","volume":"28","author":"Langemeyer","year":"2018","journal-title":"Trends Cell Biol."},{"issue":"12","key":"10.1016\/j.jri.2025.104831_bib103","doi-asserted-by":"crossref","DOI":"10.1002\/pmic.201900289","article-title":"Quantitative proteomic analysis of seminal plasma, sperm membrane proteins, and seminal extracellular vesicles suggests vesicular mechanisms aid in the removal and addition of proteins to the ram sperm membrane","volume":"20","author":"Leahy","year":"2020","journal-title":"Proteomics"},{"issue":"4","key":"10.1016\/j.jri.2025.104831_bib104","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1530\/REP-19-0600","article-title":"Canine oviductal exosomes improve oocyte development via EGFR\/MAPK signaling pathway","volume":"160","author":"Lee","year":"2020","journal-title":"Reproduction"},{"issue":"3","key":"10.1016\/j.jri.2025.104831_bib105","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1161\/HYPERTENSIONAHA.119.14081","article-title":"Unique microRNA signals in plasma exosomes from pregnancies complicated by preeclampsia","volume":"75","author":"Li","year":"2020","journal-title":"Hypertension"},{"issue":"8","key":"10.1016\/j.jri.2025.104831_bib106","doi-asserted-by":"crossref","first-page":"3950","DOI":"10.1111\/jcmm.16347","article-title":"Sertoli cell-derived exosomal MicroRNA-486-5p regulates differentiation of spermatogonial stem cell through PTEN in mice","volume":"25","author":"Li","year":"2021","journal-title":"J. Cell. Mol. Med."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib107","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1186\/s12951-021-01028-7","article-title":"The basic characteristics of extracellular vesicles and their potential application in bone sarcomas","volume":"19","author":"Li","year":"2021","journal-title":"J. Nanobiotechnology"},{"key":"10.1016\/j.jri.2025.104831_bib108","article-title":"Sertoli cell-derived exosome-mediated transfer of miR-145-5p inhibits Leydig cell steroidogenesis by targeting steroidogenic factor 1","volume":"35","author":"Liang","year":"2021"},{"key":"10.1016\/j.jri.2025.104831_bib109","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.734950","article-title":"Extracellular vesicle proteomes shed light on the evolutionary, interactive, and functional divergence of their biogenesis mechanisms","volume":"9","author":"Lim","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib110","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1186\/s12958-024-01277-9","article-title":"Identification of energy metabolism anomalies and serum biomarkers in the progression of premature ovarian failure via extracellular vesicles\u2019 proteomic and metabolomic profiles","volume":"22","author":"Liu","year":"2024","journal-title":"Reprod. Biol. Endocrinol."},{"issue":"4","key":"10.1016\/j.jri.2025.104831_bib111","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1530\/REP-08-0405","article-title":"Effects of oviductal fluid on the development, quality, and gene expression of porcine blastocysts produced in vitro","volume":"137","author":"Lloyd","year":"2009","journal-title":"Reproduction"},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib112","first-page":"185","article-title":"Endogenous retrovirus-encoded Syncytin-2 contributes to exosome-mediated immunosuppression of T cells","volume":"102","author":"Lokossou","year":"2020","journal-title":"Biol. Reprod."},{"issue":"4","key":"10.1016\/j.jri.2025.104831_bib113","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1530\/REP-16-0384","article-title":"Effect of bovine oviductal extracellular vesicles on embryo development and quality in vitro","volume":"153","author":"Lopera-Vasquez","year":"2017","journal-title":"Reproduction"},{"issue":"2","key":"10.1016\/j.jri.2025.104831_bib114","doi-asserted-by":"crossref","DOI":"10.1093\/molehr\/gaac002","article-title":"Exosomes released from Sertoli cells contribute to the survival of Leydig cells through CCL20 in rats","volume":"28","author":"Ma","year":"2022","journal-title":"Mol. Hum. Reprod."},{"key":"10.1016\/j.jri.2025.104831_bib115","doi-asserted-by":"crossref","DOI":"10.1093\/humupd\/dmv055","article-title":"Extracellular vesicles: roles in gamete maturation, fertilization and embryo implantation","author":"Machtinger","year":"2015","journal-title":"Hum. Reprod. Update"},{"issue":"2","key":"10.1016\/j.jri.2025.104831_bib116","first-page":"182","article-title":"Extracellular vesicles: roles in gamete maturation, fertilization and embryo implantation","volume":"22","author":"Machtinger","year":"2016","journal-title":"Hum. Reprod. Update"},{"issue":"21","key":"10.1016\/j.jri.2025.104831_bib117","doi-asserted-by":"crossref","first-page":"13327","DOI":"10.3390\/ijms232113327","article-title":"Extracellular Vesicles in Diffuse Large B Cell Lymphoma: Characterization and Diagnostic Potential","volume":"23","author":"Matthiesen","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"11","key":"10.1016\/j.jri.2025.104831_bib118","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1038\/nm.f.1895","article-title":"The biology of infertility: research advances and clinical challenges","volume":"14","author":"Matzuk","year":"2008","journal-title":"Nat. Med."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib119","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s43556-021-00040-5","article-title":"Extracellular vesicles (exosomes and ectosomes) play key roles in the pathology of brain diseases","volume":"2","author":"Meldolesi","year":"2021","journal-title":"Mol. Biomed."},{"issue":"5","key":"10.1016\/j.jri.2025.104831_bib120","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1111\/aji.12311","article-title":"Placenta-derived exosomes and syncytiotrophoblast microparticles and their role in human reproduction: immune modulation for pregnancy success","volume":"72","author":"Mincheva-Nilsson","year":"2014","journal-title":"Am. J. Reprod. Immunol."},{"issue":"30","key":"10.1016\/j.jri.2025.104831_bib121","doi-asserted-by":"crossref","first-page":"10513","DOI":"10.1073\/pnas.0804549105","article-title":"Circulating microRNAs as stable blood-based markers for cancer detection","volume":"105","author":"Mitchell","year":"2008","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib122","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1186\/s12931-020-01423-y","article-title":"Extracellular vesicles: novel communicators in lung diseases","volume":"21","author":"Mohan","year":"2020","journal-title":"Respir. Res."},{"key":"10.1016\/j.jri.2025.104831_bib123","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.molimm.2020.12.030","article-title":"Proteomic approaches to drive advances in helminth extracellular vesicle research","volume":"131","author":"Monta\u00f1o","year":"2021","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.jri.2025.104831_bib124","first-page":"756","article-title":"Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes","volume":"119","author":"Montecalvo","year":"2012","journal-title":"Blood J. American Soci. Hematology"},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib125","doi-asserted-by":"crossref","DOI":"10.3402\/jev.v3.24641","article-title":"Routes and mechanisms of extracellular vesicle uptake","volume":"3","author":"Mulcahy","year":"2014","journal-title":"J. Extracell. Vesicles"},{"issue":"8","key":"10.1016\/j.jri.2025.104831_bib126","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1093\/humrep\/dez114","article-title":"Proteomic analysis reveals the negative modulator of sperm function glycodelin as over-represented in semen exosomes isolated from asthenozoospermic patients","volume":"34","author":"Murdica","year":"2019","journal-title":"Hum. Reprod."},{"issue":"5","key":"10.1016\/j.jri.2025.104831_bib127","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/j.fertnstert.2019.01.030","article-title":"Seminal plasma of men with severe asthenozoospermia contain exosomes that affect spermatozoa motility and capacitation","volume":"111","author":"Murdica","year":"2019","journal-title":"Fertil. Steril."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib128","doi-asserted-by":"crossref","first-page":"8856","DOI":"10.1038\/s41598-020-65517-9","article-title":"In vitro cultured human endometrial cells release extracellular vesicles that can be uptaken by spermatozoa","volume":"10","author":"Murdica","year":"2020","journal-title":"Sci. Rep."},{"issue":"11","key":"10.1016\/j.jri.2025.104831_bib129","doi-asserted-by":"crossref","first-page":"4146","DOI":"10.1073\/pnas.1200448109","article-title":"Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein","volume":"109","author":"Nabhan","year":"2012","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib130","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1146\/annurev-immunol-042617-053010","article-title":"Apoptosis and clearance of apoptotic cells","volume":"36","author":"Nagata","year":"2018","journal-title":"Annu. Rev. Immunol."},{"issue":"6","key":"10.1016\/j.jri.2025.104831_bib131","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0158278","article-title":"Induction of IFNT-stimulated genes by conceptus-derived exosomes during the attachment period","volume":"11","author":"Nakamura","year":"2016","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.jri.2025.104831_bib132","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0058502","article-title":"Endometrial exosomes\/microvesicles in the uterine microenvironment: a new paradigm for embryo-endometrial cross talk at implantation","volume":"8","author":"Ng","year":"2013","journal-title":"PloS One"},{"key":"10.1016\/j.jri.2025.104831_bib133","doi-asserted-by":"crossref","first-page":"S91","DOI":"10.1074\/mcp.RA118.000946","article-title":"Proteomic profiling of mouse epididymosomes reveals their contributions to post-testicular sperm maturation","volume":"18","author":"Nixon","year":"2019","journal-title":"Mol. Cell. Proteom."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib134","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1038\/ncb2000","article-title":"Rab27a and Rab27b control different steps of the exosome secretion pathway","volume":"12","author":"Ostrowski","year":"2010","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.jri.2025.104831_bib135","first-page":"S69","article-title":"good things come in nano-packages. Placenta","volume":"35","author":"Ouyang","year":"2014","journal-title":"PlacentaSpecif. Micro exosomes"},{"issue":"5","key":"10.1016\/j.jri.2025.104831_bib136","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1002\/jcop.22527","article-title":"\"The worst time of my life\": Treatment-related stress and unmet needs of women living with infertility","volume":"49","author":"\u00d6zt\u00fcrk","year":"2021","journal-title":"J. Community Psychol."},{"issue":"4","key":"10.1016\/j.jri.2025.104831_bib137","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1054\/ceca.1999.0031","article-title":"Increase of human spermatozoa intracellular Ca2+ concentration after fusion with prostasomes","volume":"25","author":"Palmerini","year":"1999","journal-title":"Cell Calcium"},{"issue":"3","key":"10.1016\/j.jri.2025.104831_bib138","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/s00232-006-0009-2","article-title":"Role of cholesterol, DOTAP, and DPPC in prostasome\/spermatozoa interaction and fusion","volume":"211","author":"Palmerini","year":"2006","journal-title":"J. Membr. Biol."},{"issue":"173","key":"10.1016\/j.jri.2025.104831_bib139","doi-asserted-by":"crossref","DOI":"10.1126\/scisignal.2001595","article-title":"Ca2+ signaling tools acquired from prostasomes are required for progesterone-induced sperm motility","volume":"4","author":"Park","year":"2011","journal-title":"Sci. Signal."},{"key":"10.1016\/j.jri.2025.104831_bib140","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.jconrel.2014.07.042","article-title":"Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: a new approach for drug delivery","volume":"192","author":"Pascucci","year":"2014","journal-title":"J. Control. Release"},{"issue":"17","key":"10.1016\/j.jri.2025.104831_bib141","doi-asserted-by":"crossref","first-page":"11649","DOI":"10.1074\/jbc.M112.445304","article-title":"The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes","volume":"288","author":"Perez-Hernandez","year":"2013","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib142","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1186\/s13287-016-0429-6","article-title":"Microvesicles secreted from equine amniotic-derived cells and their potential role in reducing inflammation in endometrial cells in an in-vitro model","volume":"7","author":"Perrini","year":"2016","journal-title":"Stem Cell Res. Ther."},{"issue":"7","key":"10.1016\/j.jri.2025.104831_bib143","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/j.theriogenology.2013.01.028","article-title":"Boar seminal plasma exosomes: effect on sperm function and protein identification by sequencing","volume":"79","author":"Piehl","year":"2013","journal-title":"Theriogenology"},{"key":"10.1016\/j.jri.2025.104831_bib144","unstructured":"Piko L. Immunological phenomena in the reproductive process. 1967."},{"key":"10.1016\/j.jri.2025.104831_bib145","doi-asserted-by":"crossref","first-page":"8009","DOI":"10.2147\/IJN.S142732","article-title":"Placenta-derived exosomes: potential biomarkers of preeclampsia","author":"Pillay","year":"2017","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.jri.2025.104831_bib146","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.omtm.2019.01.001","article-title":"Improved loading of plasma-derived extracellular vesicles to encapsulate antitumor miRNAs","volume":"13","author":"Pomatto","year":"2019","journal-title":"Mol. Ther. Methods Clin. Dev."},{"issue":"6pt1","key":"10.1016\/j.jri.2025.104831_bib147","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1111\/j.1365-2605.2010.01116.x","article-title":"Prostasomes: inhibitors of capacitation and modulators of cellular signalling in human sperm","volume":"34","author":"Pons-Rejraji","year":"2011","journal-title":"Int. J. Androl."},{"key":"10.1016\/j.jri.2025.104831_bib148","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2025.1641966","article-title":"Extracellular Vesicles: key mediators in vitro embryo production","volume":"12","author":"Pournourali","year":"2025","journal-title":"Front. Vet. Sci."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib149","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s12929-016-0253-4","article-title":"Impact of stress on oocyte quality and reproductive outcome","volume":"23","author":"Prasad","year":"2016","journal-title":"J. Biomed. Sci."},{"issue":"11","key":"10.1016\/j.jri.2025.104831_bib150","doi-asserted-by":"crossref","first-page":"865","DOI":"10.3390\/ani9110865","article-title":"Improved post-thaw quality of canine semen after treatment with exosomes from conditioned medium of adipose-derived mesenchymal stem cells","volume":"9","author":"Qamar","year":"2019","journal-title":"Animals"},{"issue":"2","key":"10.1016\/j.jri.2025.104831_bib151","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1071\/RD18203","article-title":"Extracellular vesicles derived from donor oviduct fluid improved birth rates after embryo transfer in mice","volume":"31","author":"Qu","year":"2019","journal-title":"Reprod. Fertil. Dev."},{"key":"10.1016\/j.jri.2025.104831_bib152","doi-asserted-by":"crossref","first-page":"2301","DOI":"10.2147\/IJN.S354003","article-title":"Loss of renewal of extracellular vesicles: harmful effects on embryo development in vitro","author":"Qu","year":"2022","journal-title":"Int. J. Nanomed."},{"issue":"7","key":"10.1016\/j.jri.2025.104831_bib153","first-page":"1043","article-title":"Use of the Q-switched 755-nm alexandrite laser to treat recalcitrant pigment after depigmentation therapy for vitiligo","volume":"30","author":"Rao","year":"2004","journal-title":"Dermatol. Surg."},{"issue":"4","key":"10.1016\/j.jri.2025.104831_bib154","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1083\/jcb.201211138","article-title":"Extracellular vesicles: exosomes, microvesicles, and friends","volume":"200","author":"Raposo","year":"2013","journal-title":"J. Cell Biol."},{"issue":"6","key":"10.1016\/j.jri.2025.104831_bib155","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1095\/biolreprod.105.049304","article-title":"Lipid remodeling of murine epididymosomes and spermatozoa during epididymal maturation","volume":"74","author":"Rejraji","year":"2006","journal-title":"Biol. Reprod."},{"issue":"5","key":"10.1016\/j.jri.2025.104831_bib156","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/j.ejca.2013.12.019","article-title":"Regulation of exosome release from mammary epithelial and breast cancer cells\u2013a new regulatory pathway","volume":"50","author":"Riches","year":"2014","journal-title":"Eur. J. Cancer"},{"issue":"2","key":"10.1016\/j.jri.2025.104831_bib157","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1002\/mrd.1153","article-title":"Consequences of bovine oocyte maturation, fertilization or early embryo development in vitro versus in vivo: implications for blastocyst yield and blastocyst quality","volume":"61","author":"Rizos","year":"2002","journal-title":"Mol. Reprod. Dev."},{"issue":"5","key":"10.1016\/j.jri.2025.104831_bib158","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1071\/RD18450","article-title":"Follicular fluid exosomes act on the bovine oocyte to improve oocyte competence to support development and survival to heat shock","volume":"31","author":"Rodrigues","year":"2019","journal-title":"Reprod. Fertil. Dev."},{"issue":"32","key":"10.1016\/j.jri.2025.104831_bib159","doi-asserted-by":"crossref","first-page":"51515","DOI":"10.18632\/oncotarget.9862","article-title":"YKT6 expression, exosome release, and survival in non-small cell lung cancer","volume":"7","author":"Ruiz-Martinez","year":"2016","journal-title":"Oncotarget"},{"issue":"5-6","key":"10.1016\/j.jri.2025.104831_bib160","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/j.1600-0897.2006.00435.x","article-title":"Specific isolation of placenta-derived exosomes from the circulation of pregnant women and their immunoregulatory consequences 1","volume":"56","author":"Sabapatha","year":"2006","journal-title":"Am. J. Reprod. Immunol."},{"issue":"11","key":"10.1016\/j.jri.2025.104831_bib161","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0187569","article-title":"Cellular and exosome mediated molecular defense mechanism in bovine granulosa cells exposed to oxidative stress","volume":"12","author":"Saeed-Zidane","year":"2017","journal-title":"PloS One"},{"key":"10.1016\/j.jri.2025.104831_bib162","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.2741\/4466","article-title":"Sullivan R. Prostasomes, post-testicular sperm maturation and fertility","volume":"21","author":"Saez","year":"2016","journal-title":"Front Biosci."},{"issue":"2","key":"10.1016\/j.jri.2025.104831_bib163","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1002\/j.1939-4640.2003.tb02653.x","article-title":"Epididymosomes and prostasomes: their roles in posttesticular maturation of the sperm cells","volume":"24","author":"Saez","year":"2003","journal-title":"J. Androl."},{"key":"10.1016\/j.jri.2025.104831_bib164","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.theriogenology.2021.08.001","article-title":"The guardians of germ cells; Sertoli-derived exosomes against electromagnetic field-induced oxidative stress in mouse spermatogonial stem cells","volume":"173","author":"Salek","year":"2021","journal-title":"Theriogenology"},{"issue":"11","key":"10.1016\/j.jri.2025.104831_bib165","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0079636","article-title":"Hypoxia-induced changes in the bioactivity of cytotrophoblast-derived exosomes","volume":"8","author":"Salomon","year":"2013","journal-title":"PloS One"},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib166","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/s12958-018-0358-6","article-title":"The enigmatic seminal plasma: a proteomics insight from ejaculation to fertilization","volume":"16","author":"Samanta","year":"2018","journal-title":"Reprod. Biol. Endocrinol."},{"issue":"7","key":"10.1016\/j.jri.2025.104831_bib167","doi-asserted-by":"crossref","first-page":"3068","DOI":"10.1210\/jc.2013-1715","article-title":"Identification of microRNAs in human follicular fluid: characterization of microRNAs that govern steroidogenesis in vitro and are associated with polycystic ovary syndrome in vivo","volume":"98","author":"Sang","year":"2013","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.jri.2025.104831_bib168","series-title":"New Frontiers: Extracellular Vesicles","first-page":"61","article-title":"Apoptotic bodies: mechanism of formation, isolation and functional relevance","author":"Santavanond","year":"2021"},{"issue":"11","key":"10.1016\/j.jri.2025.104831_bib169","doi-asserted-by":"crossref","first-page":"2807","DOI":"10.1016\/j.cell.2021.04.041","article-title":"Endometriosis: etiology, pathobiology, and therapeutic prospects","volume":"184","author":"Saunders","year":"2021","journal-title":"Cell"},{"issue":"2","key":"10.1016\/j.jri.2025.104831_bib170","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/j.1600-0854.2004.00257.x","article-title":"Rab11 promotes docking and fusion of multivesicular bodies in a calcium-dependent manner","volume":"6","author":"Savina","year":"2005","journal-title":"Traffic"},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib171","doi-asserted-by":"crossref","DOI":"10.1038\/srep14748","article-title":"Extracellular microvesicles and invadopodia mediate non-overlapping modes of tumor cell invasion","volume":"5","author":"Sedgwick","year":"2015","journal-title":"Sci. Rep."},{"issue":"4","key":"10.1016\/j.jri.2025.104831_bib172","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1073\/pnas.1017213108","article-title":"Reactive oxygen species are indispensable in ovulation","volume":"108","author":"Shkolnik","year":"2011","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"3","key":"10.1016\/j.jri.2025.104831_bib173","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1095\/biolreprod.111.093252","article-title":"Cell-secreted vesicles in equine ovarian follicular fluid contain miRNAs and proteins: a possible new form of cell communication within the ovarian follicle","volume":"86","author":"da Silveira","year":"2012","journal-title":"Biol. Reprod."},{"issue":"6","key":"10.1016\/j.jri.2025.104831_bib174","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0179451","article-title":"Supplementation with small-extracellular vesicles from ovarian follicular fluid during in vitro production modulates bovine embryo development","volume":"12","author":"da Silveira","year":"2017","journal-title":"PloS One"},{"issue":"3","key":"10.1016\/j.jri.2025.104831_bib175","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1210\/er.2017-00229","article-title":"Extracellular vesicles in human reproduction in health and disease","volume":"39","author":"Simon","year":"2018","journal-title":"Endocr. Rev."},{"issue":"11","key":"10.1016\/j.jri.2025.104831_bib176","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0140650","article-title":"Sperm proteome maturation in the mouse epididymis","volume":"10","author":"Skerget","year":"2015","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.jri.2025.104831_bib177","doi-asserted-by":"crossref","first-page":"478","DOI":"10.4103\/aja202190","article-title":"Proteomic analysis and miRNA profiling of human testicular endothelial cell-derived exosomes: the potential effects on spermatogenesis","volume":"24","author":"Song","year":"2022","journal-title":"Asian J. Androl."},{"key":"10.1016\/j.jri.2025.104831_bib178","doi-asserted-by":"crossref","first-page":"119","DOI":"10.3389\/fendo.2018.00119","article-title":"Potential functions of IGFBP-2 for ovarian folliculogenesis and steroidogenesis","volume":"9","author":"Spitschak","year":"2018","journal-title":"Front. Endocrinol."},{"issue":"5","key":"10.1016\/j.jri.2025.104831_bib179","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/BF00255932","article-title":"Promotive effect on human sperm progressive motility by prostasomes","volume":"10","author":"Stegmayr","year":"1982","journal-title":"Urol. Res."},{"issue":"8","key":"10.1016\/j.jri.2025.104831_bib180","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/nrm2728","article-title":"Rab GTPases as coordinators of vesicle traffic","volume":"10","author":"Stenmark","year":"2009","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"3","key":"10.1016\/j.jri.2025.104831_bib181","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1002\/mrd.1080420310","article-title":"Intracellular calcium reaches different levels of elevation in hyperactivated and acrosome-reacted hamster sperm","volume":"42","author":"Suarez","year":"1995","journal-title":"Mol. Reprod. Dev."},{"key":"10.1016\/j.jri.2025.104831_bib182","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1016\/j.fertnstert.2007.06.056","article-title":"Expression of enkephalin-degrading enzymes in human semen and implications for sperm motility","volume":"89","author":"Subir\u00e1n","year":"2008","journal-title":"Fertil. Steril."},{"issue":"5","key":"10.1016\/j.jri.2025.104831_bib183","doi-asserted-by":"crossref","first-page":"726","DOI":"10.4103\/1008-682X.155255","article-title":"Epididymosomes: a heterogeneous population of microvesicles with multiple functions in sperm maturation and storage","volume":"17","author":"Sullivan","year":"2015","journal-title":"Asian J. Androl."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib184","doi-asserted-by":"crossref","first-page":"R21","DOI":"10.1530\/REP-13-0058","article-title":"Epididymosomes, prostasomes, and liposomes: their roles in mammalian male reproductive physiology","volume":"146","author":"Sullivan","year":"2013","journal-title":"Reproduction"},{"issue":"11","key":"10.1016\/j.jri.2025.104831_bib185","doi-asserted-by":"crossref","first-page":"4604","DOI":"10.21037\/qims-20-1015","article-title":"Ectosome biogenesis and release processes observed by using live-cell dynamic imaging in mammalian glial cells","volume":"11","author":"Sun","year":"2021","journal-title":"Quant. Imaging Med. Surg."},{"issue":"2","key":"10.1016\/j.jri.2025.104831_bib186","doi-asserted-by":"crossref","DOI":"10.1111\/aji.13338","article-title":"Roles of male reproductive tract extracellular vesicles in reproduction","volume":"85","author":"Tamessar","year":"2020","journal-title":"Am. J. Reprod. Immunol."},{"issue":"9","key":"10.1016\/j.jri.2025.104831_bib187","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23094535","article-title":"A role for exchange of extracellular vesicles in porcine spermatogonial co-culture","volume":"23","author":"Thiageswaran","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib188","doi-asserted-by":"crossref","DOI":"10.3402\/jev.v5.31292","article-title":"Exosomal miRNAs as cancer biomarkers and therapeutic targets","volume":"5","author":"Thind","year":"2016","journal-title":"J. Extracell. Vesicles"},{"issue":"7","key":"10.1016\/j.jri.2025.104831_bib189","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1016\/j.biomaterials.2013.11.083","article-title":"A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy","volume":"35","author":"Tian","year":"2014","journal-title":"Biomaterials"},{"key":"10.1016\/j.jri.2025.104831_bib190","first-page":"767","article-title":"Premature ovarian insufficiency: step-by-step genetics bring new insights","author":"Touraine","year":"2020","journal-title":"Elsevier"},{"issue":"4","key":"10.1016\/j.jri.2025.104831_bib191","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/j.devcel.2011.08.019","article-title":"The tetraspanin CD63 regulates ESCRT-independent and-dependent endosomal sorting during melanogenesis","volume":"21","author":"Van Niel","year":"2011","journal-title":"Dev. Cell"},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib192","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms13588","article-title":"ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins","volume":"7","author":"Villarroya-Beltri","year":"2016","journal-title":"Nat. Commun."},{"issue":"11","key":"10.1016\/j.jri.2025.104831_bib193","doi-asserted-by":"crossref","first-page":"7290","DOI":"10.1093\/nar\/gku347","article-title":"Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions","volume":"42","author":"Vojtech","year":"2014","journal-title":"Nucleic Acids Res."},{"issue":"11","key":"10.1016\/j.jri.2025.104831_bib194","doi-asserted-by":"crossref","first-page":"7290","DOI":"10.1093\/nar\/gku347","article-title":"Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions","volume":"42","author":"Vojtech","year":"2014","journal-title":"Nucleic Acids Res."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib195","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1038\/s42003-022-04050-z","article-title":"Progress and gaps of extracellular vesicle-mediated intercellular cargo transfer in the central nervous system","volume":"5","author":"Wan","year":"2022","journal-title":"Commun. Biol."},{"issue":"2","key":"10.1016\/j.jri.2025.104831_bib196","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.repbio.2019.06.003","article-title":"Exosome-derived uterine microRNAs isolated from cows with endometritis impede blastocyst development","volume":"19","author":"Wang","year":"2019","journal-title":"Reprod. Biol."},{"issue":"2","key":"10.1016\/j.jri.2025.104831_bib197","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1038\/s41422-020-00409-1","article-title":"RAB31 marks and controls an ESCRT-independent exosome pathway","volume":"31","author":"Wei","year":"2021","journal-title":"Cell Res."},{"issue":"5","key":"10.1016\/j.jri.2025.104831_bib198","doi-asserted-by":"crossref","first-page":"330","DOI":"10.2174\/1389200221666200520091511","article-title":"Role of exosomes in the exchange of spermatozoa after leaving the seminiferous tubule: a review","volume":"21","author":"Wu","year":"2020","journal-title":"Curr. Drug Metab."},{"issue":"5","key":"10.1016\/j.jri.2025.104831_bib199","doi-asserted-by":"crossref","first-page":"498","DOI":"10.3390\/membranes12050498","article-title":"Current knowledge on exosome biogenesis, cargo-sorting mechanism and therapeutic implications","volume":"12","author":"Xie","year":"2022","journal-title":"Membranes"},{"key":"10.1016\/j.jri.2025.104831_bib200","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2022.809135","article-title":"Functional Analysis and Proteomics Profiling of Extracellular Vesicles From Swine Plasma Infected by African Swine Fever Virus","volume":"12","author":"Xu","year":"2022","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.jri.2025.104831_bib201","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2024.1366992","article-title":"Extracellular vesicles affecting embryo development in vitro: a potential culture medium supplement","volume":"15","author":"Xue","year":"2024","journal-title":"Front. Pharmacol."},{"issue":"4","key":"10.1016\/j.jri.2025.104831_bib202","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1002\/aja.1001720406","article-title":"Maturation of spermatozoa in the epididymis of the Chinese hamster","volume":"172","author":"Yanagimachi","year":"1985","journal-title":"Am. J. Anat."},{"issue":"5","key":"10.1016\/j.jri.2025.104831_bib203","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1111\/andr.12412","article-title":"Comprehensive proteomics analysis of exosomes derived from human seminal plasma","volume":"5","author":"Yang","year":"2017","journal-title":"Andrology"},{"issue":"15","key":"10.1016\/j.jri.2025.104831_bib204","doi-asserted-by":"crossref","first-page":"25310","DOI":"10.18632\/oncotarget.15813","article-title":"Oxidative stress-induced apoptosis in granulosa cells involves JNK, p53 and Puma","volume":"8","author":"Yang","year":"2017","journal-title":"Oncotarget"},{"issue":"11","key":"10.1016\/j.jri.2025.104831_bib205","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0110641","article-title":"Detection of tumor cell-specific mRNA and protein in exosome-like microvesicles from blood and saliva","volume":"9","author":"Yang","year":"2014","journal-title":"PloS One"},{"issue":"6","key":"10.1016\/j.jri.2025.104831_bib206","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1007\/s11095-014-1593-y","article-title":"Exosome delivered anticancer drugs across the blood-brain barrier for brain cancer therapy in Danio rerio","volume":"32","author":"Yang","year":"2015","journal-title":"Pharm. Res."},{"issue":"5","key":"10.1016\/j.jri.2025.104831_bib207","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.423","article-title":"Quantitative proteomic biomarkers from extracellular vesicles of human seminal plasma in the differential diagnosis of azoospermia","volume":"11","author":"Yao","year":"2021","journal-title":"Clin. Transl. Med."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib208","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1186\/s12951-023-01969-1","article-title":"Apoptotic bodies: bioactive treasure left behind by the dying cells with robust diagnostic and therapeutic application potentials","volume":"21","author":"Yu","year":"2023","journal-title":"J. Nanobiotechnology"},{"key":"10.1016\/j.jri.2025.104831_bib209","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2020.594044","article-title":"Extracellular vesicles: new perspectives of regenerative and reproductive veterinary medicine","volume":"7","author":"Zakirova","year":"2020","journal-title":"Front. Vet. Sci."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib210","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/6147345","article-title":"Critical role of FoxO1 in granulosa cell apoptosis caused by oxidative stress and protective effects of grape seed procyanidin B2","volume":"2016","author":"Zhang","year":"2016","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"7","key":"10.1016\/j.jri.2025.104831_bib211","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1093\/molehr\/gap031","article-title":"The signal pathway of gonadotrophins-induced mammalian oocyte meiotic resumption","volume":"15","author":"Zhang","year":"2009","journal-title":"Mol. Hum. Reprod."},{"issue":"12","key":"10.1016\/j.jri.2025.104831_bib212","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1038\/s41556-021-00805-8","article-title":"Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets","volume":"23","author":"Zhang","year":"2021","journal-title":"Nat. Cell Biol."},{"issue":"15","key":"10.1016\/j.jri.2025.104831_bib213","doi-asserted-by":"crossref","first-page":"7334","DOI":"10.1039\/D0NR08942G","article-title":"Concentrated small extracellular vesicles from menstrual blood-derived stromal cells improve intrauterine adhesion, a pre-clinical study in a rat model","volume":"13","author":"Zhang","year":"2021","journal-title":"Nanoscale"},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib214","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s13578-019-0282-2","article-title":"Exosomes: biogenesis, biologic function and clinical potential","volume":"9","author":"Zhang","year":"2019","journal-title":"Cell Biosci."},{"issue":"6","key":"10.1016\/j.jri.2025.104831_bib215","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1007\/s12192-014-0521-8","article-title":"Identification and bioinformatics analysis of microRNAs associated with stress and immune response in serum of heat-stressed and normal Holstein cows","volume":"19","author":"Zheng","year":"2014","journal-title":"Cell Stress Chaperon."},{"key":"10.1016\/j.jri.2025.104831_bib216","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2021.789939","article-title":"Adipocytes-derived extracellular vesicle-miR-26b promotes apoptosis of cumulus cells and induces polycystic ovary syndrome","volume":"12","author":"Zhou","year":"2022","journal-title":"Front. Endocrinol."},{"issue":"1","key":"10.1016\/j.jri.2025.104831_bib217","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s12915-019-0653-5","article-title":"Mechanisms of tethering and cargo transfer during epididymosome-sperm interactions","volume":"17","author":"Zhou","year":"2019","journal-title":"BMC Biol."},{"key":"10.1016\/j.jri.2025.104831_bib218","series-title":"Exosome redux","author":"Zipkin","year":"2019"},{"issue":"4","key":"10.1016\/j.jri.2025.104831_bib219","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1093\/humupd\/dmr009","article-title":"What does it take to make a developmentally competent mammalian egg?","volume":"17","author":"Zuccotti","year":"2011","journal-title":"Hum. Reprod. Update"},{"issue":"23","key":"10.1016\/j.jri.2025.104831_bib220","doi-asserted-by":"crossref","first-page":"4497","DOI":"10.1111\/j.1742-4658.2011.08168.x","article-title":"Vesicular traffic in cell navigation","volume":"278","author":"Zylbersztejn","year":"2011","journal-title":"FEBS J."}],"container-title":["Journal of Reproductive Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165037825004097?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165037825004097?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T16:21:10Z","timestamp":1783354870000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165037825004097"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":220,"alternative-id":["S0165037825004097"],"URL":"https:\/\/doi.org\/10.1016\/j.jri.2025.104831","relation":{},"ISSN":["0165-0378"],"issn-type":[{"value":"0165-0378","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The role of extracellular vesicles in animal reproduction","name":"articletitle","label":"Article Title"},{"value":"Journal of Reproductive Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jri.2025.104831","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"104831"}}