{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:07:52Z","timestamp":1771459672699,"version":"3.50.1"},"reference-count":33,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001030","name":"National Heart Foundation of Australia","doi-asserted-by":"publisher","award":["102553"],"award-info":[{"award-number":["102553"]}],"id":[{"id":"10.13039\/501100001030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001030","name":"National Heart Foundation of Australia","doi-asserted-by":"publisher","award":["G05B 2041"],"award-info":[{"award-number":["G05B 2041"]}],"id":[{"id":"10.13039\/501100001030","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jsams.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Science and Medicine in Sport"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1016\/j.jsams.2021.09.008","type":"journal-article","created":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T09:10:28Z","timestamp":1632733828000},"page":"103-107","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Improvement in functional capacity with spironolactone masks the treatment effect on exercise blood pressure"],"prefix":"10.1016","volume":"25","author":[{"given":"Myles N.","family":"Moore","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin G.","family":"Schultz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James L.","family":"Hare","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas H.","family":"Marwick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James E.","family":"Sharman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jsams.2021.09.008_bb0005","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1093\/ajh\/hps053","article-title":"Exercise-induced hypertension, cardiovascular events, and mortality in patients undergoing exercise stress testing: a systematic review and meta-analysis","volume":"26","author":"Schultz","year":"2013","journal-title":"Am J Hypertens"},{"issue":"4","key":"10.1016\/j.jsams.2021.09.008_bb0010","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1080\/08037051.2017.1291276","article-title":"Exercise systolic blood pressure at moderate workload predicts cardiovascular disease and mortality through 35 years of follow-up in healthy, middle-aged men","volume":"26","author":"Mariampillai","year":"2017","journal-title":"Blood Press"},{"issue":"16","key":"10.1016\/j.jsams.2021.09.008_bb0015","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1016\/j.jacc.2015.08.015","article-title":"Clinical relevance of exaggerated exercise blood pressure","volume":"66","author":"Schultz","year":"2015","journal-title":"J Am Coll Cardiol"},{"issue":"5","key":"10.1016\/j.jsams.2021.09.008_bb0020","doi-asserted-by":"crossref","first-page":"284","DOI":"10.3109\/08037051.2011.566251","article-title":"Masked hypertension is \u201cunmasked\u201d by low-intensity exercise blood pressure","volume":"20","author":"Schultz","year":"2011","journal-title":"Blood Press"},{"issue":"12","key":"10.1016\/j.jsams.2021.09.008_bb0025","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1016\/j.jsams.2016.04.004","article-title":"Exaggerated blood pressure response to early stages of exercise stress testing and presence of hypertension","volume":"19","author":"Schultz","year":"2016","journal-title":"J Sci Med Sport"},{"issue":"SUPPL. A","key":"10.1016\/j.jsams.2021.09.008_bb0030","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1093\/eurheartj\/13.suppl_A.30","article-title":"Higher left ventricle mass in normotensives with exaggerated blood pressure responses to exercise associated with higher ambulatory blood pressure load and sympathetic activity","volume":"13","author":"Polonia","year":"1992","journal-title":"Eur Heart J"},{"issue":"5","key":"10.1016\/j.jsams.2021.09.008_bb0035","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1093\/ajh\/hpt008","article-title":"Impact of spironolactone on vascular, myocardial, and functional parameters in untreated patients with a hypertensive response to exercise","volume":"26","author":"Hare","year":"2013","journal-title":"Am J Hypertens"},{"issue":"5","key":"10.1016\/j.jsams.2021.09.008_bb0040","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1161\/01.CIR.0000138680.89536.A9","article-title":"Effect of aldosterone antagonism on myocardial dysfunction in hypertensive patients with diastolic heart failure","volume":"110","author":"Mottram","year":"2004","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.jsams.2021.09.008_bb0045","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.jacc.2009.03.066","article-title":"Effect of spironolactone on left ventricular mass and aortic stiffness in early-stage chronic kidney disease. A randomized controlled trial","volume":"54","author":"Edwards","year":"2009","journal-title":"J Am Coll Cardiol"},{"issue":"12","key":"10.1016\/j.jsams.2021.09.008_bb0050","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1016\/j.jcmg.2011.08.014","article-title":"A randomized study of the beneficial effects of aldosterone antagonism on left ventricular function, structure, and fibrosis markers in metabolic syndrome","volume":"4","author":"Kosmala","year":"2011","journal-title":"JACC Cardiovasc Imaging"},{"issue":"5","key":"10.1016\/j.jsams.2021.09.008_bb0055","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/j.jcmg.2017.10.007","article-title":"Association of active and passive components of left ventricular diastolic filling with exercise intolerance in heart failure with preserved ejection fraction: mechanistic insights from spironolactone response","volume":"12","author":"Kosmala","year":"2019","journal-title":"JACC Cardiovasc Imaging"},{"issue":"17","key":"10.1016\/j.jsams.2021.09.008_bb0060","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1016\/j.jacc.2016.07.763","article-title":"Effect of aldosterone antagonism on exercise tolerance in heart failure with preserved ejection fraction","volume":"68","author":"Kosmala","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jsams.2021.09.008_bb0065","article-title":"Age- and gender-specific upper limits and reference equations for workload-indexed systolic blood pressure response during bicycle ergometry","author":"Hedman","year":"2020","journal-title":"Eur J Prev Cardiol"},{"issue":"3","key":"10.1016\/j.jsams.2021.09.008_bb0070","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1097\/00008483-200205000-00009","article-title":"Determinants of exercise blood pressure response in normotensive and hypertensive women: role of cardiorespiratory fitness","volume":"22","author":"Kokkinos","year":"2002","journal-title":"J Cardiopulm Rehabil Prev"},{"issue":"1","key":"10.1016\/j.jsams.2021.09.008_bb0075","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1136\/bjsm.2008.050906","article-title":"Decreased exercise blood pressure in older adults after exercise training: contributions of increased fitness and decreased fatness","volume":"43","author":"Barone","year":"2009","journal-title":"Br J Sports Med"},{"issue":"1","key":"10.1016\/j.jsams.2021.09.008_bb0080","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1161\/01.HYP.0000250759.71323.8b","article-title":"Exercise capacity and blood pressure associations with left ventricular mass in prehypertensive individuals","volume":"49","author":"Kokkinos","year":"2007","journal-title":"Hypertension"},{"issue":"3","key":"10.1016\/j.jsams.2021.09.008_bb0085","doi-asserted-by":"crossref","first-page":"203","DOI":"10.7326\/0003-4819-116-3-203","article-title":"Is there a relationship between exercise systolic blood-pressure response and left-ventricular mass - the Framingham Heart-Study","volume":"116","author":"Lauer","year":"1992","journal-title":"Ann Intern Med"},{"issue":"6","key":"10.1016\/j.jsams.2021.09.008_bb0090","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1038\/jhh.2014.84","article-title":"Exercise blood pressure: clinical relevance and correct measurement","volume":"29","author":"Sharman","year":"2015","journal-title":"J Hum Hypertens"},{"key":"10.1016\/j.jsams.2021.09.008_bb0095","series-title":"Using multivariate statistics","author":"Tabachnick","year":"2007"},{"issue":"1","key":"10.1016\/j.jsams.2021.09.008_bb0100","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1037\/0033-2909.112.1.155","article-title":"A power primer","volume":"112","author":"Cohen","year":"1992","journal-title":"Psychol Bull"},{"issue":"11","key":"10.1016\/j.jsams.2021.09.008_bb0105","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1097\/00004872-199111000-00013","article-title":"Effect of antihypertensive medication on endurance exercise capacity in hypertensive sportsmen","volume":"9","author":"Vanhees","year":"1991","journal-title":"J Hypertens"},{"issue":"6","key":"10.1016\/j.jsams.2021.09.008_bb0110","first-page":"469","article-title":"Fosinopril in the treatment of hypertension effects on 24h ambulatory blood pressure and on blood pressure response to exercise","volume":"8","author":"Fortini","year":"1994","journal-title":"J Hum Hypertens"},{"issue":"10","key":"10.1016\/j.jsams.2021.09.008_bb0115","doi-asserted-by":"crossref","first-page":"3142","DOI":"10.1016\/j.transproceed.2007.04.029","article-title":"Acute effects of a single dose of Phosphodiesterase type 5 inhibitor (sildenafil) on systemic arterial blood pressure during exercise and 24-hour ambulatory blood pressure monitoring in heart transplant recipients","volume":"39","author":"Guimaraes","year":"2007","journal-title":"Transplant Proc"},{"issue":"9","key":"10.1016\/j.jsams.2021.09.008_bb0120","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1097\/HJH.0000000000001791","article-title":"Blood pressure response to maximal dynamic exercise testing in an athletic population","volume":"36","author":"Pressler","year":"2018","journal-title":"J Hypertens"},{"issue":"6","key":"10.1016\/j.jsams.2021.09.008_bb0125","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1038\/ajh.2008.166","article-title":"Patients with type 2 diabetes have exaggerated brachial and central exercise blood pressure: relation to left ventricular relative wall thickness","volume":"21","author":"Scott","year":"2008","journal-title":"Am J Hypertens"},{"issue":"11","key":"10.1016\/j.jsams.2021.09.008_bb0130","doi-asserted-by":"crossref","first-page":"2239","DOI":"10.1097\/HJH.0000000000000715","article-title":"Association between cardiorespiratory fitness and submaximal systolic blood pressure among young adult men: a reversed J-curve pattern relationship","volume":"33","author":"Prasad","year":"2015","journal-title":"J Hypertens"},{"issue":"5","key":"10.1016\/j.jsams.2021.09.008_bb0135","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1080\/17461391.2016.1277787","article-title":"Relation between arterial stiffness and aerobic capacity: importance of proximal aortic stiffness","volume":"17","author":"Tomoto","year":"2017","journal-title":"Eur J Sport Sci"},{"issue":"4Pt1","key":"10.1016\/j.jsams.2021.09.008_bb0140","first-page":"145","article-title":"Effects of age and aerobic capacity on arterial stiffness in healthy adults","volume":"88","author":"Vaitkevicius","year":"1993","journal-title":"Circulation"},{"issue":"9","key":"10.1016\/j.jsams.2021.09.008_bb0145","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1177\/2047487314553780","article-title":"The association of cardiorespiratory fitness with endothelial or smooth muscle vasodilator function","volume":"22","author":"Montero","year":"2015","journal-title":"Eur J Prev Cardiol"},{"issue":"12","key":"10.1016\/j.jsams.2021.09.008_bb0150","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1016\/j.amjcard.2004.03.015","article-title":"Effect of spironolactone on endothelial function in patients with congestive heart failure on conventional medical therapy","volume":"93","author":"Abiose","year":"2004","journal-title":"Am J Cardiol"},{"issue":"5","key":"10.1016\/j.jsams.2021.09.008_bb0155","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.amjcard.2009.10.057","article-title":"Comparison of myocardial ischemia on the ergocycle versus the treadmill in patients with coronary heart disease","volume":"105","author":"Noel","year":"2010","journal-title":"Am J Cardiol"},{"issue":"3","key":"10.1016\/j.jsams.2021.09.008_bb0160","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/0002-8703(82)90275-7","article-title":"Comparative analysis of physiologic responses to three different maximal graded exercise test protocols in healthy women","volume":"103","author":"Pollock","year":"1982","journal-title":"Am Heart J"},{"key":"10.1016\/j.jsams.2021.09.008_bb0165","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1038\/jhh.2013.5","article-title":"Exercise aortic stiffness: reproducibility and relation to end-organ damage in men","volume":"27","author":"Keith","year":"2013","journal-title":"J Hum Hypertens"}],"container-title":["Journal of Science and Medicine in Sport"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S144024402100253X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S144024402100253X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T17:53:13Z","timestamp":1761414793000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S144024402100253X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":33,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["S144024402100253X"],"URL":"https:\/\/doi.org\/10.1016\/j.jsams.2021.09.008","relation":{},"ISSN":["1440-2440"],"issn-type":[{"value":"1440-2440","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Improvement in functional capacity with spironolactone masks the treatment effect on exercise blood pressure","name":"articletitle","label":"Article Title"},{"value":"Journal of Science and Medicine in Sport","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jsams.2021.09.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}