{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:16:37Z","timestamp":1760955397172,"version":"build-2065373602"},"reference-count":28,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Structural Biology"],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1016\/j.jsb.2012.12.006","type":"journal-article","created":{"date-parts":[[2012,12,20]],"date-time":"2012-12-20T01:21:00Z","timestamp":1355966460000},"page":"136-148","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"title":["FASTDEF: Fast defocus and astigmatism estimation for high-throughput transmission electron microscopy"],"prefix":"10.1016","volume":"181","author":[{"given":"J.","family":"Vargas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Ot\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Marabini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Jonic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.M.","family":"de la Rosa-Trev\u00edn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.M.","family":"Carazo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.O.S.","family":"Sorzano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jsb.2012.12.006_b0005","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1006\/jmbi.1994.1406","article-title":"Electron cryomicroscopy of bacillus stearothermophilus 50S ribosomal subunits crystallized on phospholipid monolayers","volume":"239","author":"Avila-Sakar","year":"1994","journal-title":"Journal of Molecular Biology"},{"year":"1975","series-title":"Principles of Optics","author":"Born","key":"10.1016\/j.jsb.2012.12.006_b0010"},{"key":"10.1016\/j.jsb.2012.12.006_b0015","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0304-3991(97)00032-6","article-title":"A spectral estimation approach to contrast transfer function detection in electron microscopy","volume":"68","author":"Fern\u00e1ndez","year":"1997","journal-title":"Ultramicroscopy"},{"key":"10.1016\/j.jsb.2012.12.006_b0020","doi-asserted-by":"crossref","first-page":"2692","DOI":"10.1364\/JOSAA.14.002692","article-title":"Two-dimensional phase unwrapping with minimum weighted discontinuity","volume":"14","author":"Flynn","year":"1997","journal-title":"Journal of the Optical Society of America A"},{"key":"10.1016\/j.jsb.2012.12.006_b0025","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1146\/annurev.biophys.31.082901.134202","article-title":"Single-particle imaging of macromolecules by cryo-electron microscopy","volume":"31","author":"Frank","year":"2002","journal-title":"Annual Review of Biophysics and Biomolecular Structure"},{"key":"10.1016\/j.jsb.2012.12.006_b0030","first-page":"11107","article-title":"Robust two-dimensional weighted and unweighted phase unwrapping that uses fast transforms and iterative methods","volume":"11","author":"Ghihlia","year":"1994","journal-title":"Journal of the Optical Society of America A"},{"issue":"1","key":"10.1016\/j.jsb.2012.12.006_b0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jsb.2010.12.005","article-title":"Review: precise beam-tilt alignment and collimation are required to minimize the phase error associated with coma in high-resolution cryo-em","volume":"174","author":"Glaeser","year":"2011","journal-title":"Journal of Structural Biology"},{"key":"10.1016\/j.jsb.2012.12.006_b0040","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1029\/RS023i004p00713","article-title":"Satellite radar interferometry: two-dimensional phase unwrapping","volume":"23","author":"Goldstein","year":"1988","journal-title":"Radio Science"},{"key":"10.1016\/j.jsb.2012.12.006_b0045","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1017\/S0033583504003920","article-title":"Realizing the potential of electron cryo-microscopy","volume":"37","author":"Henderson","year":"2004","journal-title":"Quarterly Reviews of biophysics"},{"key":"10.1016\/j.jsb.2012.12.006_b0050","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.jsb.2003.10.011","article-title":"Automated determination of parameters describing power spectra of micrograph images in electron microscopy","volume":"144","author":"Huang","year":"2003","journal-title":"Journal of Structural Biology"},{"key":"10.1016\/j.jsb.2012.12.006_b0055","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.jsb.2006.06.014","article-title":"A novel method for improvement of visualization of power spectra for sorting cryo-electron micrographs and their local areas","volume":"157","author":"Jonic","year":"2007","journal-title":"Journal of Structural Biology"},{"key":"10.1016\/j.jsb.2012.12.006_b0060","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1364\/JOSAA.18.001862","article-title":"Natural demodulation of two-dimensional fringe patterns. I. General background of the spiral phase quadrature transform","volume":"18","author":"Larkin","year":"2001","journal-title":"Journal of the Optical Society of America A"},{"key":"10.1016\/j.jsb.2012.12.006_b0065","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1006\/jsbi.1999.4174","article-title":"EMAN: semiautomated software for high-resolution single-particle reconstructions","volume":"128","author":"Ludtke","year":"1999","journal-title":"Journal of Structural Biology"},{"key":"10.1016\/j.jsb.2012.12.006_b0070","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.ultramic.2005.02.004","article-title":"ACE: automated CTF estimation","volume":"104","author":"Mallick","year":"2005","journal-title":"Ultramicroscopy"},{"key":"10.1016\/j.jsb.2012.12.006_b0075","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1073\/pnas.1015520107","article-title":"Electron microscopy studies on the quaternary structure of p53 reveal different binding modes for p53 tetramers in complex with DNA","volume":"108","author":"Melero","year":"2011","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.jsb.2012.12.006_b0080","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/S1047-8477(03)00069-8","article-title":"Accurate determination of local defocus and specimen tilt in electron microscopy","volume":"142","author":"Mindell","year":"2003","journal-title":"Journal of Structural Biology"},{"year":"2009","series-title":"Mathematical Tables Table of Derivatives (List of Differentiation Identities)","author":"MobileReference","key":"10.1016\/j.jsb.2012.12.006_b0145"},{"key":"10.1016\/j.jsb.2012.12.006_b0090","doi-asserted-by":"crossref","first-page":"2556","DOI":"10.1364\/OE.20.002556","article-title":"Fast two-dimensional simultaneous phase unwrapping and low-pass filtering","volume":"20","author":"Navarro","year":"2012","journal-title":"Optics Express"},{"key":"10.1016\/j.jsb.2012.12.006_b0095","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1364\/JOSA.66.000207","article-title":"Zernike polynomials and atmospheric turbulence","volume":"66","author":"Noll","year":"1976","journal-title":"Journal of the Optical Society of America"},{"key":"10.1016\/j.jsb.2012.12.006_b0100","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/S1047-8477(03)00072-8","article-title":"Automatic CTF correction for single particles based upon multivariate statistical analysis of individual power spectra","volume":"142","author":"Sander","year":"2003","journal-title":"Journal of Structural Biology"},{"key":"10.1016\/j.jsb.2012.12.006_b0105","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.jsb.2004.06.006","article-title":"XMIPP: a new generation of an open-source image processing package for Electron Microscopy","volume":"148","author":"Sorzano","year":"2004","journal-title":"Journal of Structural Biology"},{"key":"10.1016\/j.jsb.2012.12.006_b0110","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.jsb.2007.08.013","article-title":"Fast, robust, and accurate determination of transmission electron microscopy contrast transfer function","volume":"160","author":"Sorzano","year":"2007","journal-title":"Journal of Structural Biology"},{"key":"10.1016\/j.jsb.2012.12.006_b0115","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1017\/S0033583500003644","article-title":"Single-particle electron cryo-microscopy: towards atomic resolution","volume":"33","author":"Van Heel","year":"2000","journal-title":"Quarterly Reviews of Biophysics"},{"key":"10.1016\/j.jsb.2012.12.006_b0120","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0304-3991(02)00377-7","article-title":"A method for estimating the CTF in electron microscopy based on ARMA models and parameter adjusting","volume":"96","author":"Vel\u00e1zquez-Muriel","year":"2003","journal-title":"Ultramicroscopy"},{"key":"10.1016\/j.jsb.2012.12.006_b0125","doi-asserted-by":"crossref","first-page":"2766","DOI":"10.1364\/JOSAA.22.002766","article-title":"Phase recovery from a single pattern using an orientational vector-field-regularized estimator","volume":"22","author":"Villa","year":"2005","journal-title":"Journal of the Optical Society of America A"},{"key":"10.1016\/j.jsb.2012.12.006_b0130","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.ultramic.2012.03.004","article-title":"Precise and unbiased estimation of astigmatism and defocus in transmission electron microscopy","volume":"116","author":"Vulovi\u0107","year":"2012","journal-title":"Ultramicroscopy"},{"key":"10.1016\/j.jsb.2012.12.006_b0135","doi-asserted-by":"crossref","first-page":"6298","DOI":"10.1073\/pnas.0914604107","article-title":"Subunit interactions in bovine papillomavirus","volume":"107","author":"Wolf","year":"2010","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.jsb.2012.12.006_b0140","first-page":"27","article-title":"Basic wavefront aberration theory for optical metrology","volume":"11","author":"Wyant","year":"1992","journal-title":"Applied Optics and Optical Engineering"}],"container-title":["Journal of Structural Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1047847712003401?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1047847712003401?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T03:14:39Z","timestamp":1760930079000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1047847712003401"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2]]},"references-count":28,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["S1047847712003401"],"URL":"https:\/\/doi.org\/10.1016\/j.jsb.2012.12.006","relation":{},"ISSN":["1047-8477"],"issn-type":[{"type":"print","value":"1047-8477"}],"subject":[],"published":{"date-parts":[[2013,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"FASTDEF: Fast defocus and astigmatism estimation for high-throughput transmission electron microscopy","name":"articletitle","label":"Article Title"},{"value":"Journal of Structural Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jsb.2012.12.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}