{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T21:37:23Z","timestamp":1791841043423,"version":"4.3.4"},"reference-count":227,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Structural Biology"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.jsb.2025.108196","type":"journal-article","created":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T12:40:38Z","timestamp":1741956038000},"page":"108196","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Dengue virus-host interactions: Structural and mechanistic insights for future therapeutic strategies"],"prefix":"10.1016","volume":"217","author":[{"given":"Moumita","family":"Khanra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Indrani","family":"Ghosh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samima","family":"Khatun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nilanjan","family":"Ghosh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shovanlal","family":"Gayen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2\u20133","key":"10.1016\/j.jsb.2025.108196_b0005","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.addr.2007.03.005","article-title":"RNAi therapeutics: principles, prospects and challenges","volume":"59","author":"Aagaard","year":"2007","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.jsb.2025.108196_b0010","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.coviro.2016.09.003","article-title":"The quest for host targets to combat dengue virus infections","volume":"20","author":"Acosta","year":"2016","journal-title":"Curr. Opin. Virol."},{"issue":"12","key":"10.1016\/j.jsb.2025.108196_b0015","doi-asserted-by":"crossref","first-page":"6968","DOI":"10.1093\/nar\/gkac473","article-title":"Insights into the product release mechanism of dengue virus NS3 helicase","volume":"50","author":"Adler","year":"2022","journal-title":"Nucleic Acids Res."},{"issue":"5","key":"10.1016\/j.jsb.2025.108196_b0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/nmicrobiol.2017.37","article-title":"Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection","volume":"2","author":"Aguirre","year":"2017","journal-title":"Nat. Microbiol."},{"issue":"8","key":"10.1016\/j.jsb.2025.108196_b0025","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1011587","article-title":"The dengue virus NS1 protein; new roles in pathogenesis due to similarities with and affinity for the high-density lipoprotein (HDL)?","volume":"19","author":"Alcal\u00e1","year":"2023","journal-title":"PLoS Pathog."},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0030","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.virol.2009.01.043","article-title":"Antiviral activity of carbohydrate-binding agents and the role of DC-SIGN in dengue virus infection","volume":"387","author":"Alen","year":"2009","journal-title":"Virology"},{"issue":"23","key":"10.1016\/j.jsb.2025.108196_b0035","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.01342-15","article-title":"Dengue virus NS1 protein modulates cellular energy metabolism by increasing glyceraldehyde-3-phosphate dehydrogenase activity","volume":"89","author":"Allonso","year":"2015","journal-title":"J. Virol."},{"issue":"25","key":"10.1016\/j.jsb.2025.108196_b0040","doi-asserted-by":"crossref","first-page":"17021","DOI":"10.1074\/jbc.M109.006239","article-title":"The polypyrimidine tract-binding protein is required for efficient dengue virus propagation and associates with the viral replication machinery","volume":"284","author":"Anwar","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jsb.2025.108196_b0045","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.virol.2022.02.001","article-title":"The interactions of flaviviruses with cellular receptors: implications for virus entry","volume":"568","author":"Anwar","year":"2022","journal-title":"Virology"},{"issue":"11","key":"10.1016\/j.jsb.2025.108196_b0050","doi-asserted-by":"crossref","first-page":"5408","DOI":"10.1128\/JVI.02188-08","article-title":"NS5 of dengue virus mediates STAT2 binding and degradation","volume":"83","author":"Ashour","year":"2009","journal-title":"J. Virol."},{"issue":"24","key":"10.1016\/j.jsb.2025.108196_b0055","doi-asserted-by":"crossref","first-page":"13094","DOI":"10.1128\/JVI.00704-13","article-title":"Nucleolin interacts with the dengue virus capsid protein and plays a role in formation of infectious virus particles","volume":"87","author":"Balinsky","year":"2013","journal-title":"J. Virol."},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0060","doi-asserted-by":"crossref","first-page":"19587","DOI":"10.1038\/s41598-020-76350-5","article-title":"Dengue virus infection impedes megakaryopoiesis in MEG-01 cells where the virus envelope protein interacts with the transcription factor TAL-1","volume":"10","author":"Banerjee","year":"2020","journal-title":"Sci. Rep."},{"issue":"4","key":"10.1016\/j.jsb.2025.108196_b0065","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1007\/s00203-024-03892-x","article-title":"Prediction of virus-host interactions and identification of hot spot residues of DENV-2 and SH3 domain interactions","volume":"206","author":"Banik","year":"2024","journal-title":"Arch. Microbiol."},{"key":"10.1016\/j.jsb.2025.108196_b0070","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.virol.2016.10.022","article-title":"Dengue virus induces mitochondrial elongation through impairment of Drp1-triggered mitochondrial fission","volume":"500","author":"Barbier","year":"2017","journal-title":"Virology"},{"issue":"2","key":"10.1016\/j.jsb.2025.108196_b0075","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.virol.2004.07.004","article-title":"The RNA helicase, nucleotide 5\u2032-triphosphatase, and RNA 5\u2032-triphosphatase activities of Dengue virus protein NS3 are Mg2+-dependent and require a functional Walker B motif in the helicase catalytic core","volume":"328","author":"Benarroch","year":"2004","journal-title":"Virology"},{"issue":"7","key":"10.1016\/j.jsb.2025.108196_b0080","doi-asserted-by":"crossref","DOI":"10.15252\/embr.202153600","article-title":"Dengue virus NS1 protein conveys pro\u2010inflammatory signals by docking onto high\u2010density lipoproteins","volume":"23","author":"Benfrid","year":"2022","journal-title":"EMBO Rep."},{"issue":"5","key":"10.1016\/j.jsb.2025.108196_b0085","doi-asserted-by":"crossref","first-page":"804","DOI":"10.3390\/v16050804","article-title":"Toward a categorization of virus-ncRNA interactions in the world of RNA to disentangle the tiny secrets of dengue virus","volume":"16","author":"Bermudez-Santana","year":"2024","journal-title":"Viruses"},{"issue":"3","key":"10.1016\/j.jsb.2025.108196_b0090","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1128\/JVI.01970-16","article-title":"The many faces of the flavivirus NS5 protein in antagonism of type I interferon signaling","volume":"91","author":"Best","year":"2017","journal-title":"J. Virol."},{"key":"10.1016\/j.jsb.2025.108196_b0095","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2021.574067","article-title":"Dengue virus non-structural protein 5 as a versatile, multi-functional effector in host\u2013pathogen interactions","volume":"11","author":"Bhatnagar","year":"2021","journal-title":"Front. Cell. Infect. Microbiol.,"},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0100","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s00284-020-02284-w","article-title":"Current understanding of the pathogenesis of dengue virus infection","volume":"78","author":"Bhatt","year":"2021","journal-title":"Curr. Microbiol."},{"issue":"4","key":"10.1016\/j.jsb.2025.108196_b0105","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/j.1462-5822.2009.01407.x","article-title":"Human Sec3 protein is a novel transcriptional and translational repressor of flavivirus","volume":"12","author":"Bhuvanakantham","year":"2010","journal-title":"Cell. Microbiol."},{"issue":"8","key":"10.1016\/j.jsb.2025.108196_b0110","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1038\/nrd.2017.33","article-title":"Broad-spectrum agents for flaviviral infections: dengue, Zika and beyond","volume":"16","author":"Boldescu","year":"2017","journal-title":"Nat. Rev. Drug Discov."},{"issue":"2","key":"10.1016\/j.jsb.2025.108196_b0115","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.antiviral.2009.11.009","article-title":"Structure and functionality in flavivirus NS-proteins: perspectives for drug design","volume":"87","author":"Bollati","year":"2010","journal-title":"Antiviral Res."},{"issue":"2","key":"10.1016\/j.jsb.2025.108196_b0120","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1517\/14712598.2015.983070","article-title":"Therapeutic face of RNAi: in vivo challenges","volume":"15","author":"Borna","year":"2015","journal-title":"Expert Opin. Biol. Ther."},{"issue":"2","key":"10.1016\/j.jsb.2025.108196_b0125","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.virol.2011.06.022","article-title":"The interaction of flavivirus M protein with light chain Tctex-1 of human dynein plays a role in late stages of virus replication","volume":"417","author":"Brault","year":"2011","journal-title":"Virology"},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0130","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1146\/annurev-virology-110615-042334","article-title":"Properties and functions of the dengue virus capsid protein","volume":"3","author":"Byk","year":"2016","journal-title":"Annu. Rev. Virol."},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0135","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1128\/AAC.01429-12","article-title":"A novel inhibitor of dengue virus replication that targets the capsid protein","volume":"57","author":"Byrd","year":"2013","journal-title":"Antimicrob. Agents Chemother."},{"issue":"9951","key":"10.1016\/j.jsb.2025.108196_b0140","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1016\/S0140-6736(14)61060-6","article-title":"Clinical efficacy and safety of a novel tetravalent dengue vaccine in healthy children in Asia: a phase 3, randomised, observer-masked, placebo-controlled trial","volume":"384","author":"Capeding","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.jsb.2025.108196_b0145","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.coviro.2018.11.010","article-title":"Genome-wide approaches to unravelling host-virus interactions in Dengue and Zika infections","volume":"34","author":"Carlin","year":"2019","journal-title":"Curr. Opin. Virol.3"},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0150","article-title":"Elevated dengue virus nonstructural protein 1 serum levels and altered Toll\u2010like receptor 4 expression, nitric oxide, and tumor necrosis factor alpha production in dengue hemorrhagic fever patients","volume":"2014","author":"Carvalho","year":"2014","journal-title":"J. Trop. Med."},{"issue":"4","key":"10.1016\/j.jsb.2025.108196_b0155","doi-asserted-by":"crossref","first-page":"2096","DOI":"10.1128\/JVI.06796-11","article-title":"Dengue virus capsid protein binding to hepatic lipid droplets (LD) is potassium ion dependent and is mediated by LD surface proteins","volume":"86","author":"Carvalho","year":"2012","journal-title":"J. Virol."},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0160","article-title":"Modulation of cytokine and cytokine receptor\/antagonist by treatment with doxycycline and tetracycline in patients with dengue fever","volume":"2011","author":"Castro","year":"2011","journal-title":"J. Immunol. Res."},{"key":"10.1016\/j.jsb.2025.108196_b0165","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.virol.2015.05.017","article-title":"Dengue virus NS1 protein interacts with the ribosomal protein RPL18: this interaction is required for viral translation and replication in Huh-7 cells","volume":"484","author":"Cervantes-Salazar","year":"2015","journal-title":"Virology"},{"issue":"5","key":"10.1016\/j.jsb.2025.108196_b0170","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1038\/ni.3393","article-title":"A phosphomimetic-based mechanism of dengue virus to antagonize innate immunity","volume":"17","author":"Chan","year":"2016","journal-title":"Nat. Immunol."},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0175","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.antiviral.2010.11.002","article-title":"Combination of \u03b1-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo","volume":"89","author":"Chang","year":"2011","journal-title":"Antiviral Res."},{"issue":"8","key":"10.1016\/j.jsb.2025.108196_b0180","doi-asserted-by":"crossref","DOI":"10.1042\/BSR20240134","article-title":"Dengue virus: pathogenesis and potential for small molecule inhibitors","volume":"44","author":"Chauhan","year":"2024","journal-title":"Biosci. Rep."},{"issue":"1\u20132","key":"10.1016\/j.jsb.2025.108196_b0185","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.virol.2013.08.009","article-title":"The interaction between claudin-1 and dengue viral prM\/M protein for its entry","volume":"446","author":"Che","year":"2013","journal-title":"Virology"},{"issue":"4","key":"10.1016\/j.jsb.2025.108196_b0190","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1007033","article-title":"Macrophage migration inhibitory factor is critical for dengue NS1-induced endothelial glycocalyx degradation and hyperpermeability","volume":"14","author":"Chen","year":"2018","journal-title":"PLoS Pathog."},{"issue":"7","key":"10.1016\/j.jsb.2025.108196_b0195","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0004828","article-title":"Dengue virus nonstructural protein 1 induces vascular leakage through macrophage migration inhibitory factor and autophagy","volume":"10","author":"Chen","year":"2016","journal-title":"PLoS Neglected Tropical Diseases"},{"issue":"7","key":"10.1016\/j.jsb.2025.108196_b0200","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1005053","article-title":"Activation of TLR2 and TLR6 by dengue NS1 protein and its implications in the immunopathogenesis of dengue virus infection","volume":"11","author":"Chen","year":"2015","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.jsb.2025.108196_b0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.antiviral.2022.105400","article-title":"Sulforaphane suppresses dengue virus replication by inhibition of dengue protease and enhancement of antiviral interferon response through Nrf2-mediated heme oxygenase-1 induction","volume":"207","author":"Chen","year":"2022","journal-title":"Antiviral Res."},{"issue":"8","key":"10.1016\/j.jsb.2025.108196_b0210","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1038\/nm0897-866","article-title":"Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate","volume":"3","author":"Chen","year":"1997","journal-title":"Nat. Med."},{"key":"10.1016\/j.jsb.2025.108196_b0215","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/s11373-007-9151-9","article-title":"The type 2 dengue virus envelope protein interacts with small ubiquitin-like modifier-1 (SUMO-1) conjugating enzyme 9 (Ubc9)","volume":"14","author":"Chiu","year":"2007","journal-title":"J. Biomed. Sci."},{"issue":"19","key":"10.1016\/j.jsb.2025.108196_b0220","doi-asserted-by":"crossref","first-page":"4893","DOI":"10.3390\/ijms20194893","article-title":"TIM-1 as a signal receptor triggers dengue virus-induced autophagy","volume":"20","author":"Chu","year":"2019","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.jsb.2025.108196_b0225","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.virusres.2004.01.025","article-title":"The non-structural 3 (NS3) protein of dengue virus type 2 interacts with human nuclear receptor binding protein and is associated with alterations in membrane structure","volume":"102","author":"Chua","year":"2004","journal-title":"Virus Res."},{"issue":"4","key":"10.1016\/j.jsb.2025.108196_b0230","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.chembiol.2016.03.010","article-title":"GNF-2 inhibits dengue virus by targeting Abl kinases and the viral E protein","volume":"23","author":"Clark","year":"2016","journal-title":"Cell Chem. Biol."},{"issue":"9","key":"10.1016\/j.jsb.2025.108196_b0235","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0024365","article-title":"Dengue virus capsid protein binds core histones and inhibits nucleosome formation in human liver cells","volume":"6","author":"Colpitts","year":"2011","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0240","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1128\/JVI.74.1.564-572.2000","article-title":"\u03b1-Glucosidase inhibitors reduce dengue virus production by affecting the initial steps of virion morphogenesis in the endoplasmic reticulum","volume":"74","author":"Courageot","year":"2000","journal-title":"J. Virol."},{"issue":"2","key":"10.1016\/j.jsb.2025.108196_b0245","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1093\/femsre\/fuu004","article-title":"Receptors and routes of dengue virus entry into the host cells","volume":"39","author":"Cruz-Oliveira","year":"2015","journal-title":"FEMS Microbiol. Rev."},{"issue":"3","key":"10.1016\/j.jsb.2025.108196_b0250","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1128\/mBio.00553-15","article-title":"Dengue virus NS proteins inhibit RIG-I\/MAVS signaling by blocking TBK1\/IRF3 phosphorylation: dengue virus serotype 1 NS4A is a unique interferon-regulating virulence determinant","volume":"6","author":"Dalrymple","year":"2015","journal-title":"MBio"},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0255","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1186\/s12964-024-01779-4","article-title":"Immunomodulation in dengue: towards deciphering dengue severity markers","volume":"22","author":"Dash","year":"2024","journal-title":"Cell Commun. Signal"},{"issue":"8","key":"10.1016\/j.jsb.2025.108196_b0260","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1005841","article-title":"The dengue virus NS5 protein intrudes in the cellular spliceosome and modulates splicing","volume":"12","author":"De Maio","year":"2016","journal-title":"PLoS Pathog."},{"issue":"9","key":"10.1016\/j.jsb.2025.108196_b0265","article-title":"Mass spectrometric analysis of host cell proteins interacting with dengue virus nonstructural protein 1 in dengue virus-infected HepG2 cells","volume":"1864","author":"Dechtawewat","year":"2016","journal-title":"BBA"},{"key":"10.1016\/j.jsb.2025.108196_b0270","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13071-016-1346-3","article-title":"Spatial variation of insecticide resistance in the dengue vector Aedes aegypti presents unique vector control challenges","volume":"9","author":"Deming","year":"2016","journal-title":"Parasit. Vectors"},{"issue":"10","key":"10.1016\/j.jsb.2025.108196_b0275","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0005879","article-title":"DenvInt: A database of protein\u2013protein interactions between dengue virus and its hosts","volume":"11","author":"Dey","year":"2017","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"11","key":"10.1016\/j.jsb.2025.108196_b0280","doi-asserted-by":"crossref","first-page":"4957","DOI":"10.1128\/JVI.74.11.4957-4966.2000","article-title":"Modulation of dengue virus infection in human cells by alpha, beta, and gamma interferons","volume":"74","author":"Diamond","year":"2000","journal-title":"J. Virol."},{"issue":"2","key":"10.1016\/j.jsb.2025.108196_b0285","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.apjtm.2016.01.015","article-title":"Dengue virus non-structural 1 protein interacts with heterogeneous nuclear ribonucleoprotein H in human monocytic cells","volume":"9","author":"Diwaker","year":"2016","journal-title":"Asian Pac. J. Trop. Med."},{"issue":"2","key":"10.1016\/j.jsb.2025.108196_b0290","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.bbrc.2016.03.120","article-title":"DDX21 translocates from nucleus to cytoplasm and stimulates the innate immune response due to dengue virus infection","volume":"473","author":"Dong","year":"2016","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jsb.2025.108196_b0295","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.621043","article-title":"Landscape of monoclonal antibodies targeting zika and dengue: therapeutic solutions and critical insights for vaccine development","volume":"11","author":"Dussupt","year":"2021","journal-title":"Front. Immunol."},{"issue":"4","key":"10.1016\/j.jsb.2025.108196_b0300","first-page":"217","article-title":"Genomics, proteomics and evolution of dengue virus","volume":"16","author":"Dwivedi","year":"2017","journal-title":"Brief. Funct. Genomics"},{"issue":"4","key":"10.1016\/j.jsb.2025.108196_b0305","doi-asserted-by":"crossref","first-page":"91","DOI":"10.3390\/v9040091","article-title":"Dengue virus non-structural protein 5","volume":"9","author":"El Sahili","year":"2017","journal-title":"Viruses"},{"issue":"4","key":"10.1016\/j.jsb.2025.108196_b0310","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1515\/BC.2009.041","article-title":"Flavivirus NS5 associates with host-cell proteins zonula occludens-1 (ZO-1) and regulating synaptic membrane exocytosis-2 (RIMS2) via an internal PDZ binding mechanism","volume":"390","author":"Ellencrona","year":"2009","journal-title":"Biol. Chem."},{"key":"10.1016\/j.jsb.2025.108196_b0315","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1146\/annurev-immunol-042617-053142","article-title":"Immune response to dengue and Zika","volume":"36","author":"Elong Ngono","year":"2018","journal-title":"Annu. Rev. Immunol."},{"issue":"6","key":"10.1016\/j.jsb.2025.108196_b0320","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1080\/07391102.2016.1179595","article-title":"Molecular dynamics study of the membrane interaction of a membranotropic dengue virus C protein-derived peptide","volume":"35","author":"Fajardo-S\u00e1nchez","year":"2017","journal-title":"J. Biomol. Struct. Dyn."},{"issue":"5","key":"10.1016\/j.jsb.2025.108196_b0325","doi-asserted-by":"crossref","first-page":"2467","DOI":"10.1128\/jvi.65.5.2467-2475.1991","article-title":"Both nonstructural proteins NS2B and NS3 are required for the proteolytic processing of dengue virus nonstructural proteins","volume":"65","author":"Falgout","year":"1991","journal-title":"J. Virol."},{"issue":"2","key":"10.1016\/j.jsb.2025.108196_b0330","first-page":"388a","article-title":"Dengue virus capsid protein interacts specifically with very low-density lipoproteins","volume":"106","author":"Faustino","year":"2014","journal-title":"Nanomedicine"},{"issue":"2","key":"10.1016\/j.jsb.2025.108196_b0335","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1021\/cb500640t","article-title":"Understanding dengue virus capsid protein disordered N-terminus and pep14-23-based inhibition","volume":"10","author":"Faustino","year":"2015","journal-title":"ACS Chem. Biol."},{"issue":"16","key":"10.1016\/j.jsb.2025.108196_b0340","doi-asserted-by":"crossref","first-page":"3870","DOI":"10.3390\/ijms20163870","article-title":"Structural and functional properties of the capsid protein of dengue and related flavivirus","volume":"20","author":"Faustino","year":"2019","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0345","doi-asserted-by":"crossref","first-page":"10592","DOI":"10.1038\/srep10592","article-title":"Understanding dengue virus capsid protein interaction with key biological targets","volume":"5","author":"Faustino","year":"2015","journal-title":"Sci. Rep."},{"issue":"11","key":"10.1016\/j.jsb.2025.108196_b0350","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1038\/ni.3849","article-title":"Anti-Dengue E-dimer epitope human antibodies have therapeutic activity against Zika virus infection","volume":"18","author":"Fernandez","year":"2017","journal-title":"Nat. Immunol."},{"issue":"13","key":"10.1016\/j.jsb.2025.108196_b0355","doi-asserted-by":"crossref","first-page":"7585","DOI":"10.1128\/JVI.00757-13","article-title":"Structural changes in dengue virus when exposed to a temperature of 37 C","volume":"87","author":"Fibriansah","year":"2013","journal-title":"J. Virol."},{"issue":"17","key":"10.1016\/j.jsb.2025.108196_b0360","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1128\/JVI.01178-20","article-title":"Mitochondrial import of dengue virus NS3 protease and cleavage of GrpEL1, a cochaperone of mitochondrial Hsp70","volume":"94","author":"Gandikota","year":"2020","journal-title":"J. Virol."},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0365","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1016\/j.bbrc.2009.11.172","article-title":"Novel binding between pre-membrane protein and claudin-1 is required for efficient dengue virus entry","volume":"391","author":"Gao","year":"2010","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"4","key":"10.1016\/j.jsb.2025.108196_b0370","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.apsb.2013.06.005","article-title":"Achieving efficient RNAi therapy: progress and challenges","volume":"3","author":"Gao","year":"2013","journal-title":"Acta Pharm. Sin. B"},{"issue":"423","key":"10.1016\/j.jsb.2025.108196_b0375","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/j.bbrc.2012.06.043","article-title":"West Nile Virus (WNV) protease and membrane interactions revealed by NMR spectroscopy","volume":"13","author":"Gayen","year":"2012","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"11","key":"10.1016\/j.jsb.2025.108196_b0380","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1006673","article-title":"Dengue virus NS1 cytokine-independent vascular leak is dependent on endothelial glycocalyx components","volume":"13","author":"Glasner","year":"2017","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.jsb.2025.108196_b0385","doi-asserted-by":"crossref","unstructured":"Gonzalez Lopez Ledesma, M.M., Costa Navarro, G., Pallares, H.M., Paletta, A., De Maio, F., Iglesias, N.G., Gebhard, L., Oviedo Rouco, S., Ojeda, D.S., de Borba, L. and Giraldo, M., 2023. Dengue virus NS5 degrades ERC1 during infection to antagonize NF-kB activation. Proc. Natl. Acad. Sci. 120(23), e2220005120. https:\/\/doi.org\/10.1073\/pnas.2220005120.","DOI":"10.1073\/pnas.2220005120"},{"issue":"6","key":"10.1016\/j.jsb.2025.108196_b0390","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1016\/j.jmb.2013.11.023","article-title":"Innate immunity to dengue virus infection and subversion of antiviral responses","volume":"426","author":"Green","year":"2014","journal-title":"J. Mol. Biol."},{"issue":"17","key":"10.1016\/j.jsb.2025.108196_b0395","doi-asserted-by":"crossref","first-page":"8828","DOI":"10.1128\/JVI.00606-08","article-title":"Characterization of dengue virus complex-specific neutralizing epitopes on envelope protein domain III of dengue 2 virus","volume":"82","author":"Gromowski","year":"2008","journal-title":"J. Virol."},{"issue":"19","key":"10.1016\/j.jsb.2025.108196_b0400","doi-asserted-by":"crossref","first-page":"8003","DOI":"10.1073\/pnas.1017338108","article-title":"Secreted dengue virus nonstructural protein NS1 is an atypical barrel-shaped high-density lipoprotein","volume":"108","author":"Gutsche","year":"2011","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"Suppl 12","key":"10.1016\/j.jsb.2025.108196_b0405","article-title":"Dengue: a continuing global threat","volume":"8","author":"Guzman","year":"2010","journal-title":"Nat. Rev. Microbiol."},{"issue":"47","key":"10.1016\/j.jsb.2025.108196_b0410","doi-asserted-by":"crossref","first-page":"6355","DOI":"10.1016\/j.vaccine.2017.09.089","article-title":"Dengvaxia sensitizes seronegatives to vaccine enhanced disease regardless of age","volume":"35","author":"Halstead","year":"2017","journal-title":"Vaccine"},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0415","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4103\/2231-0762.175416","article-title":"Dengue virus: a global human threat: review of literature","volume":"6","author":"Hasan","year":"2016","journal-title":"J. Int. Soc. Prev. Community Dent"},{"issue":"16","key":"10.1016\/j.jsb.2025.108196_b0420","doi-asserted-by":"crossref","first-page":"7219","DOI":"10.1128\/JVI.00221-16","article-title":"Dengue virus subverts host innate immunity by targeting adaptor protein MAVS","volume":"90","author":"He","year":"2016","journal-title":"J. Virol."},{"issue":"40","key":"10.1016\/j.jsb.2025.108196_b0425","doi-asserted-by":"crossref","first-page":"17345","DOI":"10.1073\/pnas.1010811107","article-title":"Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesis","volume":"107","author":"Heaton","year":"2010","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"3","key":"10.1016\/j.jsb.2025.108196_b0430","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/S2221-1691(13)60057-X","article-title":"RNAi: antiviral therapy against dengue virus","volume":"3","author":"Idrees","year":"2013","journal-title":"Asian Pac. J. Trop. Biomed."},{"key":"10.1016\/j.jsb.2025.108196_b0435","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1007\/s00705-016-2855-2","article-title":"Glycosylation of dengue virus glycoproteins and their interactions with carbohydrate receptors: possible targets for antiviral therapy","volume":"161","author":"Idris","year":"2016","journal-title":"Arch. Virol"},{"issue":"11","key":"10.1016\/j.jsb.2025.108196_b0440","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1096\/fj.99-0829com","article-title":"Dengue virus nonstructural protein 1 is expressed in a glycosyl\u2010phosphatidylinositol\u2010linked form that is capable of signal transduction","volume":"14","author":"Jacobs","year":"2000","journal-title":"The FASEB J"},{"issue":"8","key":"10.1016\/j.jsb.2025.108196_b0445","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1086\/383043","article-title":"Localization of dengue virus in naturally infected human tissues, by immunohistochemistry and in situ hybridization","volume":"189","author":"Jessie","year":"2004","journal-title":"J Infect Dis"},{"issue":"2","key":"10.1016\/j.jsb.2025.108196_b0450","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.bbrc.2009.05.036","article-title":"Polypyrimidine tract-binding protein influences negative strand RNA synthesis of dengue virus","volume":"385","author":"Jiang","year":"2009","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"5","key":"10.1016\/j.jsb.2025.108196_b0455","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1039\/b923864f","article-title":"Vimentin interacts with heterogeneous nuclear ribonucleoproteins and dengue nonstructural protein 1 and is important for viral replication and release","volume":"6","author":"Kanlaya","year":"2010","journal-title":"Mol. Biosyst."},{"issue":"8","key":"10.1016\/j.jsb.2025.108196_b0460","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0006715","article-title":"The antiparasitic drug niclosamide inhibits dengue virus infection by interfering with endosomal acidification independent of mTOR","volume":"12","author":"Kao","year":"2018","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"6","key":"10.1016\/j.jsb.2025.108196_b0465","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1016\/j.celrep.2018.10.031","article-title":"A combination of two human monoclonal antibodies prevents Zika virus escape mutations in non-human primates","volume":"25","author":"Keeffe","year":"2018","journal-title":"Cell Rep."},{"issue":"10","key":"10.1016\/j.jsb.2025.108196_b0470","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1016\/j.jiph.2023.08.001","article-title":"Dengue overview: an updated systemic review","volume":"16","author":"Khan","year":"2023","journal-title":"J. Infect. Public Health"},{"key":"10.1016\/j.jsb.2025.108196_b0475","doi-asserted-by":"crossref","DOI":"10.1016\/j.cyto.2019.154780","article-title":"Dengue virus envelope protein domain III induces pro-inflammatory signature and triggers activation of inflammasome","volume":"123","author":"Khan","year":"2019","journal-title":"Cytokine"},{"issue":"2","key":"10.1016\/j.jsb.2025.108196_b0480","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.bbrc.2012.05.137","article-title":"Interaction of dengue virus nonstructural protein 5 with Daxx modulates RANTES production","volume":"423","author":"Khunchai","year":"2012","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jsb.2025.108196_b0485","doi-asserted-by":"crossref","first-page":"12891","DOI":"10.1074\/jbc.M112.442723","article-title":"NMR analysis of a novel enzymatically active unlinked dengue NS2B-NS3 protease complex","volume":"288","author":"Kim","year":"2013","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.jsb.2025.108196_b0490","doi-asserted-by":"crossref","DOI":"10.1128\/MMBR.00035-21","article-title":"Endoplasmic reticulum chaperones in viral infection: therapeutic perspectives","volume":"85","author":"Kohli","year":"2021","journal-title":"Microbiol Mol Biol Rev"},{"key":"10.1016\/j.jsb.2025.108196_b0495","doi-asserted-by":"crossref","first-page":"6389","DOI":"10.2147\/DDDT.S94207","article-title":"Identification of covalent active site inhibitors of dengue virus protease","volume":"9","author":"Koh-Stenta","year":"2015","journal-title":"Drug Des. Devel. Ther."},{"key":"10.1016\/j.jsb.2025.108196_b0500","doi-asserted-by":"crossref","DOI":"10.1016\/j.virusres.2022.199018","article-title":"Dengue virus infection\u2013a review of pathogenesis, vaccines, diagnosis and therapy","volume":"324","author":"Kok","year":"2023","journal-title":"Virus Res."},{"key":"10.1016\/j.jsb.2025.108196_b0505","doi-asserted-by":"crossref","first-page":"542","DOI":"10.3389\/fcimb.2017.00542","article-title":"Dengue virus capsid interacts with DDX3X\u2013a potential mechanism for suppression of antiviral functions in dengue infection","volume":"7","author":"Kumar","year":"2018","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"4","key":"10.1016\/j.jsb.2025.108196_b0510","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1016\/j.bbrc.2007.08.137","article-title":"Secreted complement regulatory protein clusterin interacts with dengue virus nonstructural protein 1","volume":"362","author":"Kurosu","year":"2007","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"6","key":"10.1016\/j.jsb.2025.108196_b0515","doi-asserted-by":"crossref","first-page":"891","DOI":"10.3390\/microorganisms8060891","article-title":"Roles of macrophage migration inhibitory factor in Dengue pathogenesis: from pathogenic factor to therapeutic target","volume":"8","author":"Lai","year":"2020","journal-title":"Microorganisms"},{"issue":"8","key":"10.1016\/j.jsb.2025.108196_b0520","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.3390\/v14081808","article-title":"Flaviviridae nonstructural proteins: the role in molecular mechanisms of triggering inflammation","volume":"14","author":"Latanova","year":"2022","journal-title":"Viruses"},{"key":"10.1016\/j.jsb.2025.108196_b0525","doi-asserted-by":"crossref","first-page":"6171","DOI":"10.1128\/JVI.00546-15","article-title":"Determinants of dengue virus NS4A protein oligomerization","volume":"89","author":"Lee","year":"2015","journal-title":"J. Virol."},{"key":"10.1016\/j.jsb.2025.108196_b0530","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2022.1004608","article-title":"Innate and adaptive immune evasion by dengue virus","volume":"12","author":"Lee","year":"2022","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.jsb.2025.108196_b0535","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/BF02255946","article-title":"Immunopathogenesis of dengue virus infection","volume":"8","author":"Lei","year":"2001","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.jsb.2025.108196_b0540","doi-asserted-by":"crossref","unstructured":"Leitmeyer, K.C., Vaughn, D.W., Watts, D.M., Salas, R., Villalobos, I., de Chacon, Ramos, C. and Rico-Hesse, R., 1999. Dengue virus structural differences that correlate with pathogenesis. J. Virol. 73(6), 4738-4747. https:\/\/doi.org\/10.1128\/JVI.73.6.4738-4747.1999.","DOI":"10.1128\/JVI.73.6.4738-4747.1999"},{"issue":"2","key":"10.1016\/j.jsb.2025.108196_b0545","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1080\/15548627.2016.1265192","article-title":"Dengue and Zika viruses subvert reticulophagy by NS2B3-mediated cleavage of FAM134B","volume":"13","author":"Lennemann","year":"2017","journal-title":"Autophagy"},{"key":"10.1016\/j.jsb.2025.108196_b0550","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/978-981-10-8727-1_9","article-title":"The dengue virus replication complex: from RNA replication to protein-protein interactions to evasion of innate immunity","volume":"1062","author":"Lescar","year":"2018","journal-title":"Adv. Exp. Med. Biol.1"},{"key":"10.1016\/j.jsb.2025.108196_b0555","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1016\/j.omtn.2020.01.028","article-title":"CRISPR-Cas13a cleavage of dengue virus NS3 gene efficiently inhibits viral replication","volume":"19","author":"Li","year":"2020","journal-title":"Mol. Ther. Nucleic Acids"},{"key":"10.1016\/j.jsb.2025.108196_b0560","article-title":"Dengue virus NS4B protein as a target for developing antivirals","volume":"12","author":"Li","year":"2022","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.jsb.2025.108196_b0565","doi-asserted-by":"crossref","first-page":"231","DOI":"10.3390\/membranes12020231","article-title":"Structures and dynamics of dengue virus nonstructural membrane proteins","volume":"12","author":"Li","year":"2022","journal-title":"Membranes (Basel)"},{"key":"10.1016\/j.jsb.2025.108196_b0570","doi-asserted-by":"crossref","first-page":"3150","DOI":"10.1016\/j.bbamem.2015.09.016","article-title":"Secondary structure and membrane topology of dengue virus NS4B N-terminal 125 amino acids","volume":"1848","author":"Li","year":"2015","journal-title":"BBA"},{"key":"10.1016\/j.jsb.2025.108196_b0575","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.bbamem.2017.10.016","article-title":"Secondary structure and membrane topology of dengue virus NS4A protein in micelles","volume":"1860","author":"Li","year":"2018","journal-title":"Biochim. Biophys. Acta Biomembr."},{"key":"10.1016\/j.jsb.2025.108196_b0580","doi-asserted-by":"crossref","first-page":"12247","DOI":"10.1002\/ange.201606609","article-title":"Secondary structure and membrane topology of the full\u2010length dengue virus NS4B in micelles","volume":"128","author":"Li","year":"2016","journal-title":"Angew. Chem. Int. Ed. Engl."},{"key":"10.1016\/j.jsb.2025.108196_b0585","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.antiviral.2015.04.010","article-title":"The dengue virus NS5 protein as a target for drug discovery","volume":"119","author":"Lim","year":"2015","journal-title":"Antiviral Res."},{"issue":"2","key":"10.1016\/j.jsb.2025.108196_b0590","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.bbrc.2007.07.194","article-title":"Sensitization to Fas-mediated apoptosis by dengue virus capsid protein","volume":"362","author":"Limjindaporn","year":"2007","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"2","key":"10.1016\/j.jsb.2025.108196_b0595","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.bbrc.2008.12.070","article-title":"Interaction of dengue virus envelope protein with endoplasmic reticulum-resident chaperones facilitates dengue virus production","volume":"379","author":"Limjindaporn","year":"2009","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"3","key":"10.1016\/j.jsb.2025.108196_b0600","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.jinf.2011.11.023","article-title":"Dengue virus nonstructural protein NS1 binds to prothrombin\/thrombin and inhibits prothrombin activation","volume":"64","author":"Lin","year":"2012","journal-title":"J. Infect."},{"issue":"4","key":"10.1016\/j.jsb.2025.108196_b0605","first-page":"10","article-title":"Dengue virus hijacks a noncanonical oxidoreductase function of a cellular oligosaccharyltransferase complex","volume":"8","author":"Lin Lin","year":"2017","journal-title":"MBio"},{"issue":"6","key":"10.1016\/j.jsb.2025.108196_b0610","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.1016\/j.celrep.2019.04.051","article-title":"The ER membrane protein complex promotes biogenesis of dengue and Zika virus non-structural multi-pass transmembrane proteins to support infection","volume":"27","author":"Lin","year":"2019","journal-title":"Cell Rep."},{"issue":"3","key":"10.1016\/j.jsb.2025.108196_b0615","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.4049\/jimmunol.1302675","article-title":"Dengue viral protease interaction with NF-\u03baB inhibitor \u03b1\/\u03b2 results in endothelial cell apoptosis and hemorrhage development","volume":"193","author":"Lin","year":"2014","journal-title":"J. Immunol."},{"issue":"10","key":"10.1016\/j.jsb.2025.108196_b0620","doi-asserted-by":"crossref","first-page":"3414","DOI":"10.1073\/pnas.0305892101","article-title":"Solution structure of dengue virus capsid protein reveals another fold","volume":"101","author":"Ma","year":"2004","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0625","first-page":"44","article-title":"Role of non-coding RNAs in dengue virus-host interaction","volume":"13","author":"Madhry","year":"2021","journal-title":"FBS"},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0630","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0053535","article-title":"Identification of new protein interactions between dengue fever virus and its hosts, human and mosquito","volume":"8","author":"Mairiang","year":"2013","journal-title":"PLoS One"},{"issue":"6257","key":"10.1016\/j.jsb.2025.108196_b0635","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1126\/science.aab3369","article-title":"Dengue subgenomic RNA binds TRIM25 to inhibit interferon expression for epidemiological fitness","volume":"350","author":"Manokaran","year":"2015","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0640","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1039\/C4NP00085D","article-title":"Antiviral drug discovery: broad-spectrum drugs from nature","volume":"32","author":"Martinez","year":"2015","journal-title":"Nat. Prod. Rep."},{"issue":"3","key":"10.1016\/j.jsb.2025.108196_b0645","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1042\/BJ20112219","article-title":"The disordered N-terminal region of dengue virus capsid protein contains a lipid-droplet-binding motif","volume":"444","author":"Martins","year":"2012","journal-title":"Biochem. J."},{"issue":"10","key":"10.1016\/j.jsb.2025.108196_b0650","doi-asserted-by":"crossref","first-page":"2092","DOI":"10.3390\/v13102092","article-title":"The biogenesis of dengue virus replication organelles requires the ATPase activity of valosin-containing protein","volume":"13","author":"Mazeaud","year":"2021","journal-title":"Viruses"},{"issue":"8","key":"10.1016\/j.jsb.2025.108196_b0655","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1086\/605847","article-title":"Dengue virus NS5 inhibits interferon-\u03b1 signaling by blocking signal transducer and activator of transcription 2 phosphorylation","volume":"200","author":"Mazzon","year":"2009","journal-title":"J Infect Dis"},{"issue":"17","key":"10.1016\/j.jsb.2025.108196_b0660","doi-asserted-by":"crossref","first-page":"11053","DOI":"10.1128\/JVI.79.17.11053-11061.2005","article-title":"Dengue virus nonstructural protein NS5 induces interleukin-8 transcription and secretion","volume":"79","author":"Medin","year":"2005","journal-title":"J. Virol."},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0665","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1186\/s12985-023-02251-4","article-title":"Interactions between DC-SIGN and the envelope protein from Dengue and Zika viruses: a structural perspective based on molecular dynamics and MM\/GBSA analyses","volume":"20","author":"Menechino","year":"2023","journal-title":"Virol. J."},{"issue":"17","key":"10.1016\/j.jsb.2025.108196_b0670","doi-asserted-by":"crossref","first-page":"3368","DOI":"10.1111\/febs.13349","article-title":"Unstructural biology of the dengue virus proteins","volume":"282","author":"Meng","year":"2015","journal-title":"The FEBS. J."},{"issue":"2","key":"10.1016\/j.jsb.2025.108196_b0675","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.0040017","article-title":"The mannose receptor mediates dengue virus infection of macrophages","volume":"4","author":"Miller","year":"2008","journal-title":"PLoS Pathog."},{"issue":"12","key":"10.1016\/j.jsb.2025.108196_b0680","doi-asserted-by":"crossref","first-page":"8873","DOI":"10.1074\/jbc.M609919200","article-title":"The non-structural protein 4A of dengue virus is an integral membrane protein inducing membrane alterations in a 2K-regulated manner","volume":"282","author":"Miller","year":"2007","journal-title":"J. Biol. Chem."},{"issue":"13","key":"10.1016\/j.jsb.2025.108196_b0685","doi-asserted-by":"crossref","first-page":"8854","DOI":"10.1074\/jbc.M512697200","article-title":"Subcellular localization and membrane topology of the dengue virus type 2 non-structural protein 4B","volume":"281","author":"Miller","year":"2006","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.jsb.2025.108196_b0690","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1096\/fba.2018-00047","article-title":"Dengue NS5 modulates expression of miR\u2010590 to regulate ubiquitin\u2010specific peptidase 42 in human microglia","volume":"1","author":"Mishra","year":"2019","journal-title":"FASEB Bioadv."},{"issue":"304","key":"10.1016\/j.jsb.2025.108196_b0695","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aaa3863","article-title":"Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity","volume":"7","author":"Modhiran","year":"2015","journal-title":"Sci. Transl. Med."},{"issue":"6972","key":"10.1016\/j.jsb.2025.108196_b0700","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1038\/nature02165","article-title":"Structure of the dengue virus envelope protein after membrane fusion","volume":"427","author":"Modis","year":"2004","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.jsb.2025.108196_b0705","doi-asserted-by":"crossref","DOI":"10.1016\/j.antiviral.2013.03.008","article-title":"The flavivirus NS1 protein: molecular and structural biology, immunology, role in pathogenesis and application as a diagnostic biomarker","volume":"98","author":"Muller","year":"2013","journal-title":"Antiviral Res."},{"issue":"9","key":"10.1016\/j.jsb.2025.108196_b0710","doi-asserted-by":"crossref","first-page":"2760","DOI":"10.3390\/molecules27092760","article-title":"Delving into the therapeutic potential of Carica papaya leaf against thrombocytopenia","volume":"27","author":"Munir","year":"2022","journal-title":"Molecules"},{"issue":"13","key":"10.1016\/j.jsb.2025.108196_b0715","doi-asserted-by":"crossref","first-page":"8004","DOI":"10.1128\/JVI.79.13.8004-8013.2005","article-title":"Inhibition of alpha\/beta interferon signaling by the NS4B protein of flaviviruses","volume":"79","author":"Munoz-Jord\u00e1n","year":"2005","journal-title":"J. Virol."},{"issue":"2","key":"10.1016\/j.jsb.2025.108196_b0720","doi-asserted-by":"crossref","DOI":"10.1016\/j.biotechadv.2010.11.008","article-title":"Review of dengue virus and the development of a vaccine","volume":"29","author":"Murrell","year":"2011","journal-title":"Biotechnol. Adv."},{"key":"10.1016\/j.jsb.2025.108196_b0725","series-title":"Emerging and Reemerging Viral Pathogens","first-page":"281","article-title":"Dengue virus","author":"Murugesan","year":"2020"},{"issue":"13","key":"10.1016\/j.jsb.2025.108196_b0730","doi-asserted-by":"crossref","first-page":"6746","DOI":"10.1128\/JVI.00423-15","article-title":"Mutation of putative N-glycosylation sites on dengue virus NS4B decreases RNA replication","volume":"89","author":"Naik","year":"2015","journal-title":"J. Virol."},{"issue":"10","key":"10.1016\/j.jsb.2025.108196_b0735","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.3390\/v13101967","article-title":"Dengue virus infection: a tale of viral exploitations and host responses","volume":"13","author":"Nanaware","year":"2021","journal-title":"Viruses"},{"issue":"8","key":"10.1016\/j.jsb.2025.108196_b0740","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1002\/jmv.25646","article-title":"Dengue proteins with their role in pathogenesis, and strategies for developing an effective anti\u2010dengue treatment: a review","volume":"92","author":"Nasar","year":"2020","journal-title":"J. Med. Virol."},{"issue":"3","key":"10.1016\/j.jsb.2025.108196_b0745","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1615\/CritRevImmunol.2014010212","article-title":"Emerging concepts in dengue pathogenesis: interplay between plasmablasts, platelets, and complement in triggering vasculopathy","volume":"34","author":"Nascimento","year":"2014","journal-title":"Crit. Rev. Immunol."},{"key":"10.1016\/j.jsb.2025.108196_b0750","first-page":"1","article-title":"Pregnancy associated arbovirus infections","volume":"3","author":"Nausheen","year":"2018","journal-title":"Clin. Microbiol. Infect."},{"issue":"9","key":"10.1016\/j.jsb.2025.108196_b0755","doi-asserted-by":"crossref","first-page":"4338","DOI":"10.1128\/JVI.02574-08","article-title":"Crystal structure of dengue virus type 1 envelope protein in the postfusion conformation and its implications for membrane fusion","volume":"83","author":"Nayak","year":"2009","journal-title":"J. Virol."},{"issue":"11","key":"10.1016\/j.jsb.2025.108196_b0760","doi-asserted-by":"crossref","first-page":"2818","DOI":"10.1016\/j.bbamem.2012.06.022","article-title":"NS4A and NS4B proteins from dengue virus: membranotropic regions","volume":"1818","author":"Nem\u00e9sio","year":"2012","journal-title":"BBA"},{"issue":"4","key":"10.1016\/j.jsb.2025.108196_b0765","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1016\/j.bbrc.2014.07.016","article-title":"Dengue virus disrupts Daxx and NF-\u00ce\u00b0B interaction to induce CD137-mediated apoptosis","volume":"450","author":"Netsawang","year":"2015","journal-title":"Biochem. Biophys. Res. Commun.,"},{"issue":"2","key":"10.1016\/j.jsb.2025.108196_b0770","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.virusres.2009.11.012","article-title":"Nuclear localization of dengue virus capsid protein is required for DAXX interaction and apoptosis","volume":"147","author":"Netsawang","year":"2010","journal-title":"Virus Res."},{"issue":"3","key":"10.1016\/j.jsb.2025.108196_b0775","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2023.106197","article-title":"Self-assembly of dengue virus empty capsid-like particles in solution","volume":"26","author":"Neves-Martins","year":"2023","journal-title":"Iscience"},{"issue":"6","key":"10.1016\/j.jsb.2025.108196_b0780","doi-asserted-by":"crossref","first-page":"137","DOI":"10.3390\/v9060137","article-title":"The 5\u2032 and 3\u2032 untranslated regions of the flaviviral genome","volume":"9","author":"Ng","year":"2017","journal-title":"Viruses"},{"key":"10.1016\/j.jsb.2025.108196_b0785","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.48469","article-title":"The ER membrane protein complex is required to ensure correct topology and stable expression of flavivirus polyproteins","volume":"8","author":"Ngo","year":"2019","journal-title":"Elife"},{"key":"10.1016\/j.jsb.2025.108196_b0790","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1146\/annurev-immunol-042617-053142","article-title":"Immune response to Dengue and Zika","volume":"36","author":"Ngono","year":"2018","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.jsb.2025.108196_b0795","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/bs.aivir.2020.08.003","article-title":"Structure-guided paradigm shifts in flavivirus assembly and maturation mechanisms","volume":"108","author":"Nicholls","year":"2020","journal-title":"Adv. Virus Res."},{"issue":"5","key":"10.1016\/j.jsb.2025.108196_b0800","doi-asserted-by":"crossref","first-page":"600","DOI":"10.4014\/jmb.2210.10006","article-title":"Dengue virus 2 NS2B targets MAVS and IKK\u03b5 to evade the antiviral innate immune response","volume":"33","author":"Nie","year":"2023","journal-title":"J. Microbiol. Biotechnol."},{"issue":"5","key":"10.1016\/j.jsb.2025.108196_b0805","doi-asserted-by":"crossref","first-page":"6","DOI":"10.21315\/mjms2018.25.5.2","article-title":"Roles and prospects of dengue virus non-structural proteins as antiviral targets: an easy digest","volume":"25","author":"Norazharuddin","year":"2018","journal-title":"Malays. J. Med. Sci."},{"issue":"2","key":"10.1016\/j.jsb.2025.108196_b0810","doi-asserted-by":"crossref","first-page":"32","DOI":"10.3390\/diseases12020032","article-title":"Dengue fever epidemics and the prospect of vaccines: a systematic review and meta-analysis using clinical trials in children","volume":"12","author":"Okoye","year":"2024","journal-title":"Diseases"},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0815","doi-asserted-by":"crossref","first-page":"146","DOI":"10.4269\/ajtmh.13-0624","article-title":"A highly conserved region between amino acids 221 and 266 of dengue virus non-structural protein 1 is a major epitope region in infected patients","volume":"91","author":"Omokoko","year":"2014","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"28","key":"10.1016\/j.jsb.2025.108196_b0820","first-page":"10","article-title":"First genome sequences of dengue virus strains isolated during the first DENV-4 outbreak in S\u00e3o Paulo","volume":"5","author":"Ortiz-Baez","year":"2017","journal-title":"Brazil. Genome Announc."},{"issue":"21","key":"10.1016\/j.jsb.2025.108196_b0825","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1128\/JVI.00996-19","article-title":"Dengue virus M protein promotes NLRP3 inflammasome activation to induce vascular leakage in mice","volume":"93","author":"Pan","year":"2019","journal-title":"J. Virol."},{"issue":"4","key":"10.1016\/j.jsb.2025.108196_b0830","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.mib.2008.06.004","article-title":"Structural proteomics of dengue virus","volume":"11","author":"Perera","year":"2008","journal-title":"Curr. Opin. Microbiol."},{"issue":"3","key":"10.1016\/j.jsb.2025.108196_b0835","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.cell.2005.11.042","article-title":"Cryo-EM reconstruction of dengue virus in complex with the carbohydrate recognition domain of DC-SIGN","volume":"124","author":"Pokidysheva","year":"2006","journal-title":"Cell"},{"issue":"12","key":"10.1016\/j.jsb.2025.108196_b0840","doi-asserted-by":"crossref","first-page":"6824","DOI":"10.1093\/nar\/gkaa340","article-title":"Dengue virus targets RBM10 deregulating host cell splicing and innate immune response","volume":"48","author":"Pozzi","year":"2020","journal-title":"Nucleic Acids Res."},{"issue":"3","key":"10.1016\/j.jsb.2025.108196_b0845","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1007\/s13337-021-00700-8","article-title":"Effect of siRNA targeting dengue virus genes on replication of dengue virus: an in vitro experimental study","volume":"32","author":"Prakash","year":"2021","journal-title":"VirusDisease"},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0850","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s00232-005-0744-9","article-title":"Dengue virus M protein C-terminal peptide (DVM-C) forms ion channels","volume":"204","author":"Premkumar","year":"2005","journal-title":"J. Membr. Biol.2"},{"key":"10.1016\/j.jsb.2025.108196_b0855","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12985-016-0590-7","article-title":"Flavivirus NS1: a multifaceted enigmatic viral protein","volume":"13","author":"Rastogi","year":"2016","journal-title":"Virol. J."},{"key":"10.1016\/j.jsb.2025.108196_b0860","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.bcp.2018.04.008","article-title":"Dengue virus NS2 and NS4: Minor proteins, mammoth roles","volume":"154","author":"Reddy","year":"2018","journal-title":"Biochem. Pharmacol."},{"issue":"47","key":"10.1016\/j.jsb.2025.108196_b0865","doi-asserted-by":"crossref","first-page":"14682","DOI":"10.1073\/pnas.1508095112","article-title":"Virion-associated phosphatidylethanolamine promotes TIM1-mediated infection by Ebola, dengue, and West Nile viruses","volume":"112","author":"Richard","year":"2015","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"5","key":"10.1016\/j.jsb.2025.108196_b0870","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.tim.2011.02.002","article-title":"Partial maturation: an immune-evasion strategy of dengue virus?","volume":"19","author":"Rodenhuis-Zybert","year":"2011","journal-title":"Trends Microbiol."},{"issue":"4","key":"10.1016\/j.jsb.2025.108196_b0875","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1128\/JVI.01985-18","article-title":"The dengue virus nonstructural protein 1 (NS1) is secreted from mosquito cells in association with the intracellular cholesterol transporter chaperone caveolin complex","volume":"93","author":"Rosales Ramirez","year":"2019","journal-title":"J. Virol."},{"issue":"10","key":"10.1016\/j.jsb.2025.108196_b0880","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1000632","article-title":"Dengue virus capsid protein usurps lipid droplets for viral particle formation","volume":"5","author":"Samsa","year":"2009","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.jsb.2025.108196_b0885","doi-asserted-by":"crossref","first-page":"313","DOI":"10.3389\/fpls.2012.00313","article-title":"Investigating the role of viral integral membrane proteins in promoting the assembly of nepovirus and comovirus replication factories","volume":"3","author":"Sanfa\u00e7on","year":"2013","journal-title":"Front. Plant Sci."},{"issue":"8","key":"10.1016\/j.jsb.2025.108196_b0890","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbapap.2020.140441","article-title":"Nucleotide-dependent dynamics of the Dengue NS3 helicase","volume":"1868","author":"Sarto","year":"2020","journal-title":"Biochim Biophys Acta Proteins Proteom."},{"issue":"11","key":"10.1016\/j.jsb.2025.108196_b0895","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1005277","article-title":"Dengue virus non-structural protein 1 modulates infectious particle production via interaction with the structural proteins","volume":"11","author":"Scaturro","year":"2015","journal-title":"PLoS Pathog."},{"issue":"19","key":"10.1016\/j.jsb.2025.108196_b0900","doi-asserted-by":"crossref","first-page":"11540","DOI":"10.1128\/JVI.01745-14","article-title":"Characterization of the mode of action of a potent dengue virus capsid inhibitor","volume":"88","author":"Scaturro","year":"2014","journal-title":"J. Virol."},{"key":"10.1016\/j.jsb.2025.108196_b0905","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s12918-017-0518-x","article-title":"Dengue virus causes changes of MicroRNAgenes regulatory network revealing potential targets for antiviral drugs","volume":"12","author":"Shahen","year":"2018","journal-title":"BMC Syst. Biol."},{"issue":"25","key":"10.1016\/j.jsb.2025.108196_b0910","doi-asserted-by":"crossref","first-page":"6052","DOI":"10.1016\/j.cell.2021.11.010","article-title":"The epitope arrangement on flavivirus particles contributes to Mab C10\u2019s extraordinary neutralization breadth across Zika and dengue viruses","volume":"184","author":"Sharma","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.jsb.2025.108196_b0915","doi-asserted-by":"crossref","first-page":"352","DOI":"10.3389\/fimmu.2020.00352","article-title":"Dengue virus serotype 2 and its non-structural proteins 2A and 2B activate NLRP3 inflammasome","volume":"11","author":"Shrivastava","year":"2020","journal-title":"Front. Immunol."},{"issue":"9","key":"10.1016\/j.jsb.2025.108196_b0920","doi-asserted-by":"crossref","first-page":"2879","DOI":"10.3390\/nu12092879","article-title":"Immune modulatory effects of vitamin D on viral infections","volume":"12","author":"Siddiqui","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.jsb.2025.108196_b0925","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1007\/s00705-011-0969-0","article-title":"The dengue virus nonstructural protein 1 (NS1) increases NF-\u03baB transcriptional activity in HepG2 cells","volume":"156","author":"Silva","year":"2011","journal-title":"Arch. Virol"},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0930","doi-asserted-by":"crossref","first-page":"2651","DOI":"10.1038\/s41598-019-39157-7","article-title":"Dengue virus nonstructural 3 protein interacts directly with human glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and reduces its glycolytic activity","volume":"9","author":"Silva","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jsb.2025.108196_b0935","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/s12929-024-01030-9","article-title":"Dengue virus pathogenesis and host molecular machineries","volume":"31","author":"Sinha","year":"2024","journal-title":"J. Biomed. Sci."},{"issue":"11","key":"10.1016\/j.jsb.2025.108196_b0940","doi-asserted-by":"crossref","DOI":"10.1099\/jgv.0.001693","article-title":"Revisiting dengue virus-mosquito interactions: molecular insights into viral fitness","volume":"102","author":"Siriphanitchakorn","year":"2021","journal-title":"J. Gen. Virol."},{"issue":"10","key":"10.1016\/j.jsb.2025.108196_b0945","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1099\/jgv.0.001134","article-title":"Human glucose-regulated protein 78 modulates intracellular production and secretion of nonstructural protein 1 of dengue virus","volume":"99","author":"Songprakhon","year":"2018","journal-title":"J. Gen. Virol."},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0950","doi-asserted-by":"crossref","first-page":"227","DOI":"10.3390\/biomedicines11010227","article-title":"Potential protective effect of dengue NS1 human monoclonal antibodies against dengue and zika virus infections","volume":"11","author":"Sootichote","year":"2023","journal-title":"Biomedicines"},{"issue":"9","key":"10.1016\/j.jsb.2025.108196_b0955","doi-asserted-by":"crossref","first-page":"4308","DOI":"10.1128\/JVI.00223-16","article-title":"SUMO.modification stabilizes dengue virus nonstructural protein 5 to support virus replication","volume":"90","author":"Su","year":"2016","journal-title":"J. Virol."},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0960","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s13578-023-00957-0","article-title":"Flavivirus prM interacts with MDA5 and MAVS to inhibit RLR antiviral signaling","volume":"13","author":"Sui","year":"2023","journal-title":"Cell Biosci."},{"issue":"22","key":"10.1016\/j.jsb.2025.108196_b0965","doi-asserted-by":"crossref","first-page":"12904","DOI":"10.1093\/nar\/gkx1127","article-title":"NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication","volume":"45","author":"Swarbrick","year":"2017","journal-title":"Nucleic Acids Res."},{"issue":"5","key":"10.1016\/j.jsb.2025.108196_b0970","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1016\/j.cell.2015.10.046","article-title":"Defining Hsp70 subnetworks in dengue virus replication reveals key vulnerability in flavivirus infection","volume":"163","author":"Taguwa","year":"2015","journal-title":"Cell"},{"issue":"12","key":"10.1016\/j.jsb.2025.108196_b0975","doi-asserted-by":"crossref","first-page":"6793","DOI":"10.1128\/JVI.00045-14","article-title":"Rab18 facilitates dengue virus infection by targeting fatty acid synthase to sites of viral replication","volume":"88","author":"Tang","year":"2014","journal-title":"J. Virol."},{"issue":"4","key":"10.1016\/j.jsb.2025.108196_b0980","doi-asserted-by":"crossref","first-page":"2379","DOI":"10.1074\/jbc.M114.607341","article-title":"The C-terminal 50 amino acid residues of dengue NS3 protein are important for NS3-NS5 interaction and viral replication","volume":"290","author":"Tay","year":"2015","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b0985","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1111\/imr.12367","article-title":"Fc receptors in antibody\u2010dependent enhancement of viral infections","volume":"268","author":"Taylor","year":"2015","journal-title":"Immunol. Rev."},{"issue":"4","key":"10.1016\/j.jsb.2025.108196_b0990","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1128\/JVI.01249-13","article-title":"Cellular vimentin regulates construction of dengue virus replication complexes through interaction with NS4A protein","volume":"88","author":"Teo","year":"2014","journal-title":"J. Virol."},{"issue":"3","key":"10.1016\/j.jsb.2025.108196_b0995","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1007\/s40259-022-00531-z","article-title":"Dengue vaccines: an update","volume":"36","author":"Torres-Flores","year":"2022","journal-title":"BioDrugs"},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b1000","first-page":"19839","article-title":"Dengue viruses\u2013an overview","volume":"3","author":"Tuiskunen B\u00e4ck","year":"2013","journal-title":"Infect. Ecol. Epidemiol."},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b1005","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1039\/D2RA04836A","article-title":"Identification of new inhibitors of NS5 from dengue virus using saturation transfer difference (STD-NMR) and molecular docking studies","volume":"13","author":"Ullah","year":"2023","journal-title":"RSC Adv."},{"issue":"9","key":"10.1016\/j.jsb.2025.108196_b1010","doi-asserted-by":"crossref","first-page":"2605","DOI":"10.1099\/vir.0.81844-0","article-title":"Dengue virus NS4B interacts with NS3 and dissociates it from single-stranded RNA","volume":"87","author":"Umareddy","year":"2006","journal-title":"J. Gen. Virol."},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b1015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41426-018-0168-0","article-title":"Dengue virus and the host innate immune response","volume":"7","author":"Uno","year":"2018","journal-title":"Emerg. Microbes Infect."},{"issue":"21","key":"10.1016\/j.jsb.2025.108196_b1020","doi-asserted-by":"crossref","first-page":"12019","DOI":"10.1128\/JVI.00300-07","article-title":"Characterization of the early events in dengue virus cell entry by biochemical assays and single-virus tracking","volume":"81","author":"Van der Schaar","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.jsb.2025.108196_b1025","first-page":"31","article-title":"Are aptamers really promising for diagnostic or therapeutic applications in dengue?","volume":"41","author":"Vashisht","year":"2020","journal-title":"Dengue"},{"key":"10.1016\/j.jsb.2025.108196_b1030","doi-asserted-by":"crossref","first-page":"520","DOI":"10.3389\/fimmu.2014.00520","article-title":"IgG subclasses and allotypes: from structure to effector functions","volume":"5","author":"Vidarsson","year":"2014","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jsb.2025.108196_b1035","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0074-7696(05)45006-8","article-title":"Interactions between virus proteins and host cell membranes during the viral life cycle","volume":"245","author":"Villanueva","year":"2005","journal-title":"Int. Rev. Cytol."},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b1040","doi-asserted-by":"crossref","first-page":"44","DOI":"10.3390\/v14010044","article-title":"Potential role of flavivirus NS2B-NS3 proteases in viral pathogenesis and anti-flavivirus drug discovery employing animal cells and models: a review","volume":"14","author":"Wahaab","year":"2021","journal-title":"Viruses"},{"key":"10.1016\/j.jsb.2025.108196_b1045","doi-asserted-by":"crossref","DOI":"10.1016\/j.antiviral.2022.105423","article-title":"Flavivirus NS4B protein: structure, function, and antiviral discovery","volume":"207","author":"Wang","year":"2022","journal-title":"Antiviral Res."},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b1050","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1099\/vir.0.037317-0","article-title":"Residues in domain III of the dengue virus envelope glycoprotein involved in cell-surface glycosaminoglycan binding","volume":"93","author":"Watterson","year":"2012","journal-title":"J. Gen. Virol."},{"issue":"14","key":"10.1016\/j.jsb.2025.108196_b1055","doi-asserted-by":"crossref","first-page":"8698","DOI":"10.1128\/JVI.79.14.8698-8706.2005","article-title":"Castanospermine, a potent inhibitor of dengue virus infection in vitro and in vivo","volume":"79","author":"Whitby","year":"2005","journal-title":"J. Virol."},{"issue":"6","key":"10.1016\/j.jsb.2025.108196_b1060","doi-asserted-by":"crossref","first-page":"470","DOI":"10.3390\/pathogens9060470","article-title":"Adaptive immunity to dengue virus: slippery slope or solid ground for rational vaccine design?","volume":"9","author":"Wilken","year":"2020","journal-title":"Pathogens"},{"key":"10.1016\/j.jsb.2025.108196_b1065","doi-asserted-by":"crossref","unstructured":"Wong RR., Abd-Aziz N., Affendi S., Poh CL., 2020. Role of microRNAs in antiviral responses to dengue infection. J. Biomed. Sci. 2020;27(1):4. https:\/\/10.1186\/s12929-019-0614-x.","DOI":"10.1186\/s12929-019-0614-x"},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b1070","doi-asserted-by":"crossref","first-page":"8449","DOI":"10.1038\/s41598-018-26800-y","article-title":"Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody 513","volume":"8","author":"Wong","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jsb.2025.108196_b1075","doi-asserted-by":"crossref","first-page":"4609","DOI":"10.1128\/JVI.02424-12","article-title":"Membrane topology and function of dengue virus NS2A protein","volume":"87","author":"Xie","year":"2013","journal-title":"J. Virol."},{"key":"10.1016\/j.jsb.2025.108196_b1080","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.chom.2019.09.015","article-title":"Dengue NS2A protein orchestrates virus assembly","volume":"26","author":"Xie","year":"2019","journal-title":"Cell Host Microbe"},{"issue":"16","key":"10.1016\/j.jsb.2025.108196_b1085","doi-asserted-by":"crossref","first-page":"10278","DOI":"10.1128\/JVI.79.16.10278-10288.2005","article-title":"Structure of the Dengue virus helicase\/nucleoside triphosphatase catalytic domain at a resolution of 2.4 A","volume":"79","author":"Xu","year":"2005","journal-title":"J. Virol."},{"issue":"12","key":"10.1016\/j.jsb.2025.108196_b1090","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1005350","article-title":"Dengue virus impairs mitochondrial fusion by cleaving mitofusins","volume":"11","author":"Yu","year":"2015","journal-title":"PLoS Pathog."},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b1095","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1038\/s41392-021-00554-y","article-title":"Cytosolic DNA sensing by cGAS: regulation, function, and human diseases","volume":"6","author":"Yu","year":"2021","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.jsb.2025.108196_b1100","doi-asserted-by":"crossref","DOI":"10.1016\/j.virusres.2024.199314","article-title":"Harnessing CRISPR technology for viral therapeutics and vaccines: from preclinical studies to clinical applications","volume":"341","author":"Zahedipour","year":"2024","journal-title":"Virus Res."},{"issue":"38","key":"10.1016\/j.jsb.2025.108196_b1105","doi-asserted-by":"crossref","first-page":"15978","DOI":"10.1073\/pnas.1108558108","article-title":"Squalamine as a broad-spectrum systemic antiviral agent with therapeutic potential","volume":"108","author":"Zasloff","year":"2011","journal-title":"PNAS"},{"issue":"3","key":"10.1016\/j.jsb.2025.108196_b1110","doi-asserted-by":"crossref","DOI":"10.5808\/gi.23035","article-title":"M Protein from Dengue virus oligomerizes to pentameric channel protein: in silico analysis study","volume":"21","author":"Zeba","year":"2023","journal-title":"Genomics Inform."},{"issue":"1","key":"10.1016\/j.jsb.2025.108196_b1115","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s41182-023-00504-0","article-title":"Epidemiology, biology, pathogenesis, clinical manifestations, and diagnosis of dengue virus infection, and its trend in Ethiopia: a comprehensive literature review","volume":"51","author":"Zerfu","year":"2023","journal-title":"Trop. Med. Health"},{"key":"10.1016\/j.jsb.2025.108196_b1120","doi-asserted-by":"crossref","first-page":"1940","DOI":"10.3390\/vaccines10111940","article-title":"Preparedness for the dengue epidemic: vaccine as a Viable approach","volume":"10","author":"Zeyaullah","year":"2022","journal-title":"Vaccines"},{"key":"10.1016\/j.jsb.2025.108196_b1125","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13567-021-00966-2","article-title":"Structure and function of capsid protein in flavivirus infection and its applications in the development of vaccines and therapeutics","volume":"52","author":"Zhang","year":"2021","journal-title":"Vet. Res."},{"issue":"3","key":"10.1016\/j.jsb.2025.108196_b1130","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1004682","article-title":"A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication","volume":"11","author":"Zhao","year":"2015","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.jsb.2025.108196_b1135","doi-asserted-by":"crossref","first-page":"3471","DOI":"10.1128\/JVI.03454-14","article-title":"Mapping the Interactions between the NS4B and NS3 proteins of dengue virus","volume":"89","author":"Zou","year":"2015","journal-title":"J. Virol."}],"container-title":["Journal of Structural Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1047847725000310?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1047847725000310?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T14:57:39Z","timestamp":1762354659000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1047847725000310"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":227,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["S1047847725000310"],"URL":"https:\/\/doi.org\/10.1016\/j.jsb.2025.108196","relation":{},"ISSN":["1047-8477"],"issn-type":[{"value":"1047-8477","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dengue virus-host interactions: Structural and mechanistic insights for future therapeutic strategies","name":"articletitle","label":"Article Title"},{"value":"Journal of Structural Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jsb.2025.108196","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"108196"}}