{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T20:12:05Z","timestamp":1774469525091,"version":"3.50.1"},"reference-count":30,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:00:00Z","timestamp":1277942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:00:00Z","timestamp":1277942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Steroid Biochemistry and Molecular Biology"],"published-print":{"date-parts":[[2010,7]]},"DOI":"10.1016\/j.jsbmb.2010.03.064","type":"journal-article","created":{"date-parts":[[2010,3,31]],"date-time":"2010-03-31T04:42:48Z","timestamp":1270010568000},"page":"193-198","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":55,"title":["Vitamin D inhibition of TACE and prevention of renal osteodystrophy and cardiovascular mortality"],"prefix":"10.1016","volume":"121","author":[{"given":"Adriana","family":"Dusso","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Vittoria","family":"Arcidiacono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masanori","family":"Tokumoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jsbmb.2010.03.064_bib1","doi-asserted-by":"crossref","first-page":"S14","DOI":"10.1046\/j.1523-1755.1999.07304.x","article-title":"Pathogenesis of secondary hyperparathyroidism","volume":"73","author":"Slatopolsky","year":"1999","journal-title":"Kidney Int. Suppl."},{"issue":"4","key":"10.1016\/j.jsbmb.2010.03.064_bib2","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1681\/ASN.2004070573","article-title":"Activated injectable vitamin d and hemodialysis survival: a historical cohort study","volume":"16","author":"Teng","year":"2005","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.jsbmb.2010.03.064_bib3","doi-asserted-by":"crossref","DOI":"10.1152\/ajprenal.00167.2005","article-title":"A critical role for enhanced-TGF{alpha} and EGFR expression in the initiation of parathyroid hyperplasia in experimental kidney disease","author":"Cozzolino","year":"2005","journal-title":"Am. J. Physiol. Renal Physiol."},{"issue":"2","key":"10.1016\/j.jsbmb.2010.03.064_bib4","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1681\/ASN.2007040406","article-title":"EGFR activation increases parathyroid hyperplasia and calcitriol resistance in kidney disease","volume":"19","author":"Arcidiacono","year":"2008","journal-title":"J. Am. Soc. Nephrol."},{"issue":"23","key":"10.1016\/j.jsbmb.2010.03.064_bib5","doi-asserted-by":"crossref","first-page":"24179","DOI":"10.1074\/jbc.M312141200","article-title":"Selective roles for tumor necrosis factor alpha-converting enzyme\/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: the juxtamembrane stalk determines cleavage efficiency","volume":"279","author":"Hinkle","year":"2004","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.jsbmb.2010.03.064_bib6","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1023\/A:1026343528967","article-title":"ErbB receptors and EGF-like ligands: cell lineage determination and oncogenesis through combinatorial signaling","volume":"2","author":"Pinkas-Kramarski","year":"1997","journal-title":"J. Mammary Gland Biol. Neoplasia"},{"issue":"5 Pt 1","key":"10.1016\/j.jsbmb.2010.03.064_bib7","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1203\/01.PDR.0000159513.51898.60","article-title":"Transforming growth factor alpha (TGF-alpha) and other targets of tumor necrosis factor-alpha converting enzyme (TACE) in murine polycystic kidney disease","volume":"57","author":"Nemo","year":"2005","journal-title":"Pediatr. Res."},{"issue":"2","key":"10.1016\/j.jsbmb.2010.03.064_bib8","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1172\/JCI29518","article-title":"Targeting TACE-dependent EGFR ligand shedding in breast cancer","volume":"117","author":"Kenny","year":"2007","journal-title":"J. Clin. Invest."},{"issue":"16","key":"10.1016\/j.jsbmb.2010.03.064_bib9","doi-asserted-by":"crossref","first-page":"8083","DOI":"10.1158\/0008-5472.CAN-06-1595","article-title":"Multiple acquired renal carcinoma tumor capabilities abolished upon silencing of ADAM17","volume":"66","author":"Franovic","year":"2006","journal-title":"Cancer Res."},{"issue":"13","key":"10.1016\/j.jsbmb.2010.03.064_bib10","doi-asserted-by":"crossref","first-page":"2808","DOI":"10.1111\/j.1432-1033.2004.04215.x","article-title":"Tumour necrosis factor-alpha stimulates expression of TNF-alpha converting enzyme in endothelial cells","volume":"271","author":"Bzowska","year":"2004","journal-title":"Eur. J. Biochem."},{"issue":"11","key":"10.1016\/j.jsbmb.2010.03.064_bib11","doi-asserted-by":"crossref","first-page":"8325","DOI":"10.1074\/jbc.M608826200","article-title":"Post-transcriptional up-regulation of ADAM17 upon epidermal growth factor receptor activation and in breast tumors","volume":"282","author":"Santiago-Josefat","year":"2007","journal-title":"J. Biol. Chem."},{"issue":"28","key":"10.1016\/j.jsbmb.2010.03.064_bib12","doi-asserted-by":"crossref","first-page":"25933","DOI":"10.1074\/jbc.M301673200","article-title":"Impaired trafficking and activation of tumor necrosis factor-alpha-converting enzyme in cell mutants defective in protein ectodomain shedding","volume":"278","author":"Borroto","year":"2003","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.jsbmb.2010.03.064_bib13","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1038\/sj.onc.1209779","article-title":"Differential regulation of tumor necrosis factor-alpha-converting enzyme and angiotensin-converting enzyme by type I and II interferons in human normal and leukemic myeloid cells","volume":"26","author":"Obeid","year":"2007","journal-title":"Oncogene"},{"issue":"24","key":"10.1016\/j.jsbmb.2010.03.064_bib14","doi-asserted-by":"crossref","first-page":"6962","DOI":"10.1093\/emboj\/18.24.6962","article-title":"Ectodomain shedding of TGF-alpha and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades","volume":"18","author":"Fan","year":"1999","journal-title":"EMBO J."},{"issue":"41","key":"10.1016\/j.jsbmb.2010.03.064_bib15","doi-asserted-by":"crossref","first-page":"38965","DOI":"10.1074\/jbc.M203736200","article-title":"1,25-Dihydroxyvitamin D down-regulates cell membrane growth- and nuclear growth-promoting signals by the epidermal growth factor receptor","volume":"277","author":"Cordero","year":"2002","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.jsbmb.2010.03.064_bib16","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1128\/MCB.25.1.472-487.2005","article-title":"Functional cooperation between CCAAT\/enhancer-binding proteins and the vitamin D receptor in regulation of 25-hydroxyvitamin D3 24-hydroxylase","volume":"25","author":"Dhawan","year":"2005","journal-title":"Mol. Cell. Biol."},{"issue":"1\/5","key":"10.1016\/j.jsbmb.2010.03.064_bib17","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.jsbmb.2004.03.092","article-title":"1alpha-Hydroxylase transactivation by gamma-interferon in murine macrophages requires enhanced C\/EBPbeta expression and activation","volume":"89\/90","author":"Esteban","year":"2004","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.jsbmb.2010.03.064_bib18","doi-asserted-by":"crossref","DOI":"10.2215\/CJN.01150308","article-title":"Vitamin D and kidney disease","author":"Al-Badr","year":"2008","journal-title":"Clin. J. Am. Soc. Nephrol."},{"issue":"8","key":"10.1016\/j.jsbmb.2010.03.064_bib19","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1038\/nm1275","article-title":"Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: a new therapeutic approach","volume":"11","author":"Lautrette","year":"2005","journal-title":"Nat. Med."},{"key":"10.1016\/j.jsbmb.2010.03.064_bib20","doi-asserted-by":"crossref","DOI":"10.1152\/ajprenal.90610.2008","article-title":"ADAM17 upregulation in human renal disease: a role in modulating TGF-{alpha} availability?","author":"Melenhorst","year":"2009","journal-title":"Am. J. Physiol. Renal Physiol."},{"issue":"2","key":"10.1016\/j.jsbmb.2010.03.064_bib21","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1172\/JCI8315","article-title":"Targeted expression of a dominant-negative EGF-R in the kidney reduces tubulo-interstitial lesions after renal injury","volume":"106","author":"Terzi","year":"2000","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.jsbmb.2010.03.064_bib22","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1046\/j.1523-1755.2001.00042.x","article-title":"p21WAF1 and TGF\u03b1 mediate the parathyroid growth arrest by vitamin D and high calcium","volume":"60","author":"Cozzolino","year":"2001","journal-title":"Kidney Int."},{"issue":"1","key":"10.1016\/j.jsbmb.2010.03.064_bib23","doi-asserted-by":"crossref","first-page":"F191","DOI":"10.1152\/ajprenal.00015.2009","article-title":"Improvement of renal hemodynamics during hypertension-induced chronic renal disease: role of EGF receptor antagonism","volume":"297","author":"Helle","year":"2009","journal-title":"Am. J. Physiol. Renal Physiol."},{"issue":"6","key":"10.1016\/j.jsbmb.2010.03.064_bib24","doi-asserted-by":"crossref","first-page":"3157","DOI":"10.1074\/jbc.M510797200","article-title":"Tumor necrosis factor-alpha-converting enzyme (TACE\/ADAM-17) mediates the ectodomain cleavage of intercellular adhesion molecule-1 (ICAM-1)","volume":"281","author":"Tsakadze","year":"2006","journal-title":"J. Biol. Chem."},{"issue":"39","key":"10.1016\/j.jsbmb.2010.03.064_bib25","doi-asserted-by":"crossref","first-page":"37459","DOI":"10.1074\/jbc.M305877200","article-title":"Stimulated shedding of vascular cell adhesion molecule 1 (VCAM-1) is mediated by tumor necrosis factor-alpha-converting enzyme (ADAM 17)","volume":"278","author":"Garton","year":"2003","journal-title":"J. Biol. Chem."},{"issue":"12","key":"10.1016\/j.jsbmb.2010.03.064_bib26","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1007\/BF03345654","article-title":"Renoprotective effect of rosiglitazone through the suppression of renal intercellular adhesion molecule-1 expression in streptozotocin-induced diabetic rats","volume":"31","author":"Qian","year":"2008","journal-title":"J. Endocrinol. Invest."},{"issue":"2","key":"10.1016\/j.jsbmb.2010.03.064_bib27","doi-asserted-by":"crossref","first-page":"c117","DOI":"10.1159\/000191205","article-title":"Increased plasma and endothelial cell expression of chemokines and adhesion molecules in chronic kidney disease","volume":"111","author":"Stinghen","year":"2009","journal-title":"Nephron Clin. Pract."},{"issue":"12","key":"10.1016\/j.jsbmb.2010.03.064_bib28","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1097\/TP.0b013e3181903d25","article-title":"Circulating markers of endothelial dysfunction interact with proteinuria in predicting mortality in renal transplant recipients","volume":"86","author":"van Ree","year":"2008","journal-title":"Transplantation"},{"issue":"5","key":"10.1016\/j.jsbmb.2010.03.064_bib29","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.trsl.2007.12.005","article-title":"Arterial calcification: a tumor necrosis factor-alpha mediated vascular Wnt-opathy","volume":"151","author":"Al-Aly","year":"2008","journal-title":"Transl. Res."},{"issue":"10","key":"10.1016\/j.jsbmb.2010.03.064_bib30","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1007\/s00109-008-0375-6","article-title":"Polymorphisms of the tumor necrosis factor-alpha (TNF) and the TNF-alpha converting enzyme (TACE\/ADAM17) genes in relation to cardiovascular mortality: the AtheroGene study","volume":"86","author":"Morange","year":"2008","journal-title":"J. Mol. Med."}],"container-title":["The Journal of Steroid Biochemistry and Molecular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960076010001639?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960076010001639?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T23:38:10Z","timestamp":1760744290000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960076010001639"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7]]},"references-count":30,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["S0960076010001639"],"URL":"https:\/\/doi.org\/10.1016\/j.jsbmb.2010.03.064","relation":{},"ISSN":["0960-0760"],"issn-type":[{"value":"0960-0760","type":"print"}],"subject":[],"published":{"date-parts":[[2010,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Vitamin D inhibition of TACE and prevention of renal osteodystrophy and cardiovascular mortality","name":"articletitle","label":"Article Title"},{"value":"The Journal of Steroid Biochemistry and Molecular Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jsbmb.2010.03.064","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}