{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T12:31:03Z","timestamp":1782995463851,"version":"3.54.5"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Steroid Biochemistry and Molecular Biology"],"published-print":{"date-parts":[[2015,4]]},"DOI":"10.1016\/j.jsbmb.2015.01.022","type":"journal-article","created":{"date-parts":[[2015,1,27]],"date-time":"2015-01-27T11:49:30Z","timestamp":1422359370000},"page":"14-18","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":51,"special_numbering":"C","title":["Iatrogenic vitamin D toxicity in an infant \u2013 a case report and review of literature"],"prefix":"10.1016","volume":"148","author":[{"given":"Hemamalini","family":"Ketha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather","family":"Wadams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aida","family":"Lteif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravinder J.","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jsbmb.2015.01.022_bib0005","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1373\/clinchem.2010.157115","article-title":"Increasing liquid chromatography-tandem mass spectrometry throughput by mass tagging: a sample-multiplexed high-throughput assay for 25-hydroxyvitamin D2 and D3","volume":"57","author":"Netzel","year":"2011","journal-title":"Clin. Chem."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0010","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1373\/clinchem.2010.161174","article-title":"Quantification of 1alpha,25-dihydroxy vitamin D by immunoextraction and liquid chromatography\u2013tandem mass spectrometry","volume":"57","author":"Strathmann","year":"2011","journal-title":"Clin. Chem."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0015","doi-asserted-by":"crossref","first-page":"3055","DOI":"10.1210\/jc.2006-0710","article-title":"C-3 epimers can account for a significant proportion of total circulating 25-hydroxyvitamin D in infants, complicating accurate measurement and interpretation of vitamin D status","volume":"91","author":"Singh","year":"2006","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0020","doi-asserted-by":"crossref","first-page":"6199","DOI":"10.1073\/pnas.1221255110","article-title":"Sclerostin alters serum vitamin D metabolite and fibroblast growth factor 23 concentrations and the urinary excretion of calcium","volume":"110","author":"Ryan","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0025","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1038\/ejcn.2013.278","article-title":"Pharmacokinetics of daily versus monthly vitamin D3 supplementation in non-lactating women","volume":"68","author":"Meekins","year":"2014","journal-title":"Eur. J. Clin. Nutr."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0030","doi-asserted-by":"crossref","first-page":"582S","DOI":"10.1093\/ajcn\/88.2.582S","article-title":"Pharmacokinetics of vitamin D toxicity","volume":"88","author":"Jones","year":"2008","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0035","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.abb.2010.10.012","article-title":"1,25-Dihydroxyvitamin D is not responsible for toxicity caused by vitamin D or 25-hydroxyvitamin D","volume":"505","author":"Deluca","year":"2011","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0040","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1093\/ajcn\/69.5.842","article-title":"Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety","volume":"69","author":"Vieth","year":"1999","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0045","doi-asserted-by":"crossref","first-page":"E423","DOI":"10.1210\/jc.2011-1935","article-title":"Hypercalcemia, hypercalciuria, and elevated calcitriol concentrations with autosomal dominant transmission due to cyp24a1 mutations: effects of ketoconazole therapy","volume":"97","author":"Tebben","year":"2012","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0050","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1056\/NEJMoa1103864","article-title":"Mutations in cyp24a1 and idiopathic infantile hypercalcemia","volume":"365","author":"Schlingmann","year":"2011","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0055","first-page":"jc20133802","article-title":"A lifetime of hypercalcemia and hypercalciuria, finally explained","author":"Jacobs","year":"2014","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0060","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1038\/ki.2012.193","article-title":"The serum 24,25-dihydroxyvitamin D concentration, a marker of vitamin D catabolism, is reduced in chronic kidney disease","volume":"82","author":"Bosworth","year":"2012","journal-title":"Kidney Int."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0065","doi-asserted-by":"crossref","first-page":"2567","DOI":"10.1210\/jc.2013-4388","article-title":"Clinical utility of simultaneous quantitation of 25-hydroxyvitamin D and 24,25-dihydroxyvitamin D by LC\u2013MS\/MS involving derivatization with DMEQ-TAD","volume":"99","author":"Kaufmann","year":"2014","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0070","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1001\/jamainternmed.2013.3812","article-title":"Over-the-counter and compounded vitamin D: is potency what we expect?","volume":"173","author":"LeBlanc","year":"2013","journal-title":"JAMA Intern. Med."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0075","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1373\/clinchem.2012.193185","article-title":"Vitamin D and mortality: a mendelian randomization study","volume":"59","author":"Trummer","year":"2013","journal-title":"Clin. Chem."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0080","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/s00198-008-0662-7","article-title":"Effects of a long-term vitamin D and calcium supplementation on falls and parameters of muscle function in community-dwelling older individuals","volume":"20","author":"Pfeifer","year":"2009","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0085","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1001\/archinternmed.2007.31","article-title":"Effects of ergocalciferol added to calcium on the risk of falls in elderly high-risk women","volume":"168","author":"Prince","year":"2008","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0090","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1056\/NEJM199112263252604","article-title":"Effects of therapy in x-linked hypophosphatemic rickets","volume":"325","author":"Verge","year":"1991","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0095","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0140-6736(00)40673-2","article-title":"The toxicity of vitamin D","volume":"217","author":"Tu-Tunji","year":"1931","journal-title":"Lancet"},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0100","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/S0022-3476(52)80301-4","article-title":"Vitamin D intoxication in infancy: a report of four cases","volume":"41","author":"Ross","year":"1952","journal-title":"J. Pediatr."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0105","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/2193-1801-2-5","article-title":"Deficiencies in immunoassay methods used to monitor serum estradiol levels during aromatase inhibitor treatment in postmenopausal breast cancer patients","volume":"2","author":"Jaque","year":"2013","journal-title":"Springerplus"},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0110","first-page":"239","article-title":"Nephrocalcinosis due to vitamin D intoxication","volume":"31","author":"Besbas","year":"1989","journal-title":"Turk. J. Pediatr."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0115","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1136\/bmj.1.5386.834-a","article-title":"Dangers of vitamin-D intoxication","volume":"1","author":"Dent","year":"1964","journal-title":"Br. Med. J."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0120","doi-asserted-by":"crossref","first-page":"196","DOI":"10.7326\/0003-4819-82-2-196","article-title":"Vitamin D intoxication in an anephric child","volume":"82","author":"Counts","year":"1975","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0125","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1136\/adc.36.188.373","article-title":"Hypervitaminosis D with osteosclerosis","volume":"36","author":"Dewind","year":"1961","journal-title":"Arch. Dis. Child."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0130","doi-asserted-by":"crossref","first-page":"e453","DOI":"10.1542\/peds.2004-2580","article-title":"Acute vitamin D intoxication in a child","volume":"116","author":"Barrueto","year":"2005","journal-title":"Pediatrics"},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0135","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1297\/cpe.16.89","article-title":"Acute vitamin D toxicity in an infant","volume":"16","author":"Khadgawat","year":"2007","journal-title":"Clin. Pediatr. Endocrinol."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0140","doi-asserted-by":"crossref","first-page":"602","DOI":"10.7326\/0003-4819-128-7-199804010-00028","article-title":"Anemia secondary to vitamin D intoxication","volume":"128","author":"Puig","year":"1998","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0145","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/8756-3282(94)90707-2","article-title":"Hypercalcemia and hyperosteolysis in vitamin D intoxication: effects of clodronate therapy","volume":"15","author":"Rizzoli","year":"1994","journal-title":"Bone"},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0150","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1001\/archinte.1976.03630110017008","article-title":"Vitamin D metabolism in man: effect of corticosteroids","volume":"136","author":"Lukert","year":"1976","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0155","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1001\/archinte.1979.03630460018009","article-title":"Glucocorticoid effects in vitamin D intoxication","volume":"139","author":"Streck","year":"1979","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0160","first-page":"380","article-title":"An unusual case of vitamin D toxicity","volume":"54","author":"Sterling","year":"1967","journal-title":"Acta Endocrinol. (Copenh.)"},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0165","first-page":"976","article-title":"Clinicopathological conference; vitamin D intoxication; a metabolic psychosis","volume":"2","author":"Aub","year":"1951","journal-title":"Am. Pract. Dig. Treat."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0170","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/S0140-6736(02)07814-5","article-title":"Vitamin D poisoning by table sugar","volume":"359","author":"Vieth","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0175","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1007\/BF02429107","article-title":"25-Hydroxy-vitamin D levels in a patient with hypervitaminosis D","volume":"56","author":"Lilienfeld-Toal","year":"1978","journal-title":"Klin. Wochenschr."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0180","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1111\/j.0954-6820.1969.tb07313.x","article-title":"Metastatic calcification of soft tissue on overdosage of vitamin D","volume":"185","author":"Irnell","year":"1969","journal-title":"Acta Med. Scand."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0185","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.2105\/AJPH.85.10.1418","article-title":"Subclinical health effects in a population exposed to excess vitamin D in milk","volume":"85","author":"Scanlon","year":"1995","journal-title":"Am. J. Public Health"},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0190","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1056\/NEJM199204303261801","article-title":"Hypervitaminosis-D associated with drinking milk","volume":"326","author":"Jacobus","year":"1992","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0195","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1136\/pgmj.62.733.1025","article-title":"Another family with acute vitamin-D intoxication \u2013 another cause of familial hypercalcemia","volume":"62","author":"Thomson","year":"1986","journal-title":"Postgrad. Med. J."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0200","doi-asserted-by":"crossref","first-page":"511","DOI":"10.7326\/0003-4819-122-7-199504010-00006","article-title":"Serum levels of free 1,25-dihydroxyvitamin-D in vitamin-D toxicity","volume":"122","author":"Pettifor","year":"1995","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0205","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1056\/NEJMc063341","article-title":"Dietary supplement-induced vitamin D intoxication","volume":"357","author":"Klontz","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0210","first-page":"917","article-title":"Unusual cases of chronic intoxication by vitamin D","volume":"16","author":"Chiricone","year":"2003","journal-title":"J. Nephrol."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0215","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1136\/bmj.290.6470.748","article-title":"Prolonged hypercalcaemia after industrial exposure to vitamin D3","volume":"290","author":"Jibani","year":"1985","journal-title":"Br. Med. J."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0220","unstructured":"Dietary reference intakes for calcium and vitamin D: The National Academies Press; 2011."},{"key":"10.1016\/j.jsbmb.2015.01.022_bib0225","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1111\/j.1365-2265.2005.02383.x","article-title":"Milk-alkali syndrome is a major cause of hypercalcaemia among non-end-stage renal disease (non-esrd) inpatients","volume":"63","author":"Picolos","year":"2005","journal-title":"Clin. Endocrinol. (Oxford)"}],"container-title":["The Journal of Steroid Biochemistry and Molecular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960076015000345?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960076015000345?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T23:49:18Z","timestamp":1760744958000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960076015000345"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4]]},"references-count":45,"alternative-id":["S0960076015000345"],"URL":"https:\/\/doi.org\/10.1016\/j.jsbmb.2015.01.022","relation":{},"ISSN":["0960-0760"],"issn-type":[{"value":"0960-0760","type":"print"}],"subject":[],"published":{"date-parts":[[2015,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Iatrogenic vitamin D toxicity in an infant \u2013 a case report and review of literature","name":"articletitle","label":"Article Title"},{"value":"The Journal of Steroid Biochemistry and Molecular Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jsbmb.2015.01.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}