{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T08:56:17Z","timestamp":1772787377261,"version":"3.50.1"},"reference-count":80,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,4,20]],"date-time":"2018-04-20T00:00:00Z","timestamp":1524182400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Steroid Biochemistry and Molecular Biology"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.jsbmb.2018.04.009","type":"journal-article","created":{"date-parts":[[2018,4,21]],"date-time":"2018-04-21T14:17:21Z","timestamp":1524320241000},"page":"37-49","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Fetuin B links vitamin D deficiency and pediatric obesity: Direct negative regulation by vitamin D"],"prefix":"10.1016","volume":"182","author":[{"given":"Gillian E.","family":"Walker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonia","family":"Follenzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina","family":"Bruscaggin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcello","family":"Manfredi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simonetta","family":"Bellone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emilio","family":"Marengo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi","family":"Maiuri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Flavia","family":"Prodam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianni","family":"Bona","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jsbmb.2018.04.009_bib0005","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1056\/NEJMra070553","article-title":"Vitamin D deficiency","volume":"357","author":"Holick","year":"2007","journal-title":"N. Engl. J. Med."},{"issue":"2","key":"10.1016\/j.jsbmb.2018.04.009_bib0010","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s11154-017-9424-1","article-title":"The vitamin D deficiency pandemic: approaches for diagnosis, treatment and prevention","volume":"18","author":"Holick","year":"2017","journal-title":"Rev. Endocr. Metab. Disord."},{"issue":"19","key":"10.1016\/j.jsbmb.2018.04.009_bib0015","doi-asserted-by":"crossref","first-page":"3407","DOI":"10.3748\/wjg.v23.i19.3407","article-title":"Morini S relationship between adipose tissue dysfunction, vitamin D deficiency and the pathogenesis of non-alcoholic fatty liver disease","volume":"23","author":"Cimini","year":"2017","journal-title":"World J. Gastroenterol."},{"issue":"2","key":"10.1016\/j.jsbmb.2018.04.009_bib0020","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/s11154-017-9417-0","article-title":"Vitamin-D concentrations, cardiovascular risk and events - a review of epidemiological evidence","volume":"18","author":"Gr\u00fcbler","year":"2017","journal-title":"Rev. Endocr. Metab. Disord."},{"issue":"3","key":"10.1016\/j.jsbmb.2018.04.009_bib0025","first-page":"1379","article-title":"Vitamin D and mortality","volume":"36","author":"Pilz","year":"2016","journal-title":"Anticancer Res."},{"key":"10.1016\/j.jsbmb.2018.04.009_bib0030","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.ijcard.2016.12.053","article-title":"Vitamin D and cardiovascular disease: from atherosclerosis to myocardial infarction and stroke","volume":"230","author":"Muscogiuri","year":"2017","journal-title":"Int. J. Cardiol."},{"issue":"4","key":"10.1016\/j.jsbmb.2018.04.009_bib0035","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.beem.2011.05.010","article-title":"Vitamin D receptor (VDR)-mediated actions of 1\u03b1,25(OH)\u2082vitamin D\u2083: genomic and non-genomic mechanisms","volume":"25","author":"Haussler","year":"2011","journal-title":"Best Pract. Res. Clin. Endocrinol. Metab."},{"issue":"3","key":"10.1016\/j.jsbmb.2018.04.009_bib0040","doi-asserted-by":"crossref","first-page":"135","DOI":"10.3390\/nu8030135","article-title":"The non-genomic actions of vitamin D","volume":"8","author":"Hii","year":"2016","journal-title":"Nutrients"},{"key":"10.1016\/j.jsbmb.2018.04.009_bib0045","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/bs.afnr.2015.11.001","article-title":"Calcium and vitamin D in obesity and related chronic disease","volume":"77","author":"Pannu","year":"2016","journal-title":"Adv. Food Nutr. Res."},{"issue":"4","key":"10.1016\/j.jsbmb.2018.04.009_bib0050","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/obr.12239","article-title":"Obesity and vitamin D deficiency: a systematic review and meta-analysis","volume":"16","author":"Pereira-Santos","year":"2015","journal-title":"Obes. Rev."},{"issue":"2","key":"10.1016\/j.jsbmb.2018.04.009_bib0055","doi-asserted-by":"crossref","first-page":"e1001383","DOI":"10.1371\/journal.pmed.1001383","article-title":"Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts","volume":"10","author":"Vimaleswaran","year":"2013","journal-title":"PLoS Med."},{"key":"10.1016\/j.jsbmb.2018.04.009_bib0060","doi-asserted-by":"crossref","first-page":"e68689","DOI":"10.1371\/journal.pone.0068689","article-title":"Hypovitaminosis D is independently associated with metabolic syndrome in obese patients","volume":"8","author":"Barchetta","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jsbmb.2018.04.009_bib0065","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/1475-2840-13-57","article-title":"Altered glucose metabolism rather than naive type 2 diabetes mellitus (T2DM) is related to vitamin D status in severe obesity","volume":"13","author":"Bellan","year":"2014","journal-title":"Cardiovasc. Diabetol."},{"issue":"1","key":"10.1016\/j.jsbmb.2018.04.009_bib0070","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2016-0076","article-title":"Prepubertal adiposity, vitamin D Status, and insulin resistance","volume":"138","author":"Cediel","year":"2016","journal-title":"Pediatrics"},{"issue":"5","key":"10.1016\/j.jsbmb.2018.04.009_bib0075","doi-asserted-by":"crossref","DOI":"10.3390\/nu9050459","article-title":"Acute vitamin D\u2083 supplementation in severe obesity: evaluation of multimeric adiponectin","volume":"9","author":"Mai","year":"2017","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.jsbmb.2018.04.009_bib0080","doi-asserted-by":"crossref","first-page":"242","DOI":"10.2337\/db09-1011","article-title":"Adiposity, cardiometabolic risk, and vitamin D status: the Framingham heart study","volume":"59","author":"Cheng","year":"2010","journal-title":"Diabetes"},{"issue":"4","key":"10.1016\/j.jsbmb.2018.04.009_bib0085","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1097\/MPG.0000000000001598","article-title":"Vitamin D Status, cardiometabolic, liver and mental health status in obese youth attending a pediatric weight management Centre","volume":"65","author":"MacDonald","year":"2017","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"issue":"5","key":"10.1016\/j.jsbmb.2018.04.009_bib0090","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1210\/jc.2010-2388","article-title":"Vitamin D status, adiposity, and lipids in black American and Caucasian children","volume":"96","author":"Rajakumar","year":"2011","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"5","key":"10.1016\/j.jsbmb.2018.04.009_bib0095","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1038\/ijo.2012.112","article-title":"Expression of vitamin D-metabolizing enzymes in human adipose tissue -- the effect of obesity and diet-induced weight loss","volume":"37","author":"Wamberg","year":"2013","journal-title":"Int. J. Obes. (Lond.)"},{"issue":"7-8","key":"10.1016\/j.jsbmb.2018.04.009_bib0100","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1515\/jpem-2013-0379","article-title":"Association between vitamin D level and cardiovascular risk in obese children and adolescents","volume":"27","author":"Atabek","year":"2014","journal-title":"J. Pediatr. Endocrinol. Metab."},{"issue":"1","key":"10.1016\/j.jsbmb.2018.04.009_bib0105","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.nut.2013.05.018","article-title":"National report on the association of serum vitamin D with cardiometabolic risk factors in the pediatric population of the Middle East and North Africa (MENA): the CASPIAN-III study","volume":"30","author":"Kelishadi","year":"2014","journal-title":"Nutrition"},{"issue":"12","key":"10.1016\/j.jsbmb.2018.04.009_bib0110","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1111\/jpc.12935","article-title":"Low vitamin D is associated with hypertension in paediatric obesity","volume":"51","author":"Kao","year":"2015","journal-title":"J. Paediatr. Child Health"},{"issue":"10","key":"10.1016\/j.jsbmb.2018.04.009_bib0115","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1111\/apa.13363","article-title":"Vitamin D deficiency is associated with prediabetes in obese Swedish children","volume":"105","author":"Ekbom","year":"2016","journal-title":"Acta Paediatr."},{"issue":"9","key":"10.1016\/j.jsbmb.2018.04.009_bib0120","doi-asserted-by":"crossref","first-page":"e0162554","DOI":"10.1371\/journal.pone.0162554","article-title":"Vitamin D deficiency and glycemic Status in children and adolescents with type 1 diabetes mellitus","volume":"11","author":"Savastio","year":"2016","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.jsbmb.2018.04.009_bib0125","doi-asserted-by":"crossref","first-page":"323","DOI":"10.20960\/nh.412","article-title":"Association between vitamin D levels and cardiovascular risk factors in obese children and adolescents","volume":"34","author":"Gul","year":"2017","journal-title":"Nutr. Hosp."},{"issue":"1","key":"10.1016\/j.jsbmb.2018.04.009_bib0130","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1017\/S0954422412000029","article-title":"Calcium and vitamin D in obesity","volume":"25","author":"Song","year":"2012","journal-title":"Nutr. Res. Rev."},{"issue":"3","key":"10.1016\/j.jsbmb.2018.04.009_bib0135","doi-asserted-by":"crossref","first-page":"403","DOI":"10.5604\/12321966.1219177","article-title":"Hypovitaminosis D and adipose tissue - cause and effect relationships in obesity","volume":"23","author":"Pelczy\u0144ska","year":"2016","journal-title":"Ann. Agric. Environ. Med."},{"issue":"1","key":"10.1016\/j.jsbmb.2018.04.009_bib0140","doi-asserted-by":"crossref","first-page":"e83685","DOI":"10.1371\/journal.pone.0083685","article-title":"Pediatric obesity and vitamin D deficiency: a proteomic approach identifies multimeric adiponectin as a key link between these conditions","volume":"9","author":"Walker","year":"2014","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.jsbmb.2018.04.009_bib0145","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1530\/eje.0.1480293","article-title":"The role of the novel adipocyte-derived hormone adiponectin in human disease","volume":"148","author":"D\u00edez","year":"2003","journal-title":"Eur. J. Endocrinol."},{"key":"10.1016\/j.jsbmb.2018.04.009_bib0150","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1007\/BF03344156","article-title":"Italian cross-sectional growth charts for height, weight and BMI (2 to 20 yr)","volume":"29","author":"Cacciari","year":"2006","journal-title":"J. Endocrinol. Invest."},{"issue":"7","key":"10.1016\/j.jsbmb.2018.04.009_bib0155","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1210\/jc.2011-0385","article-title":"Evaluation, treatment, and prevention of vitamin D deficiency: an endocrine society clinical practice guideline","volume":"96","author":"Holick","year":"2011","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.jsbmb.2018.04.009_bib0160","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1136\/adc.51.3.170","article-title":"Clinical longitudinal standards for height, weight, height velocity, weight velocity, and stages of puberty","volume":"51","author":"Tanner","year":"1976","journal-title":"Arch Dis. Child"},{"key":"10.1016\/j.jsbmb.2018.04.009_bib0165","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.jpeds.2015.12.032","article-title":"Influence of ultraviolet radiation on the association between 25-hydroxy vitamin D levels and cardiovascular risk factors in obesity","volume":"171","author":"Prodam","year":"2016","journal-title":"J. Pediatr."},{"key":"10.1016\/j.jsbmb.2018.04.009_bib0170","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.3001249","article-title":"Recommendations for biomarker identification and qualification in clinical proteomics","volume":"2","author":"Mischak","year":"2010","journal-title":"Sci. Transl. Med."},{"issue":"6","key":"10.1016\/j.jsbmb.2018.04.009_bib0175","doi-asserted-by":"crossref","first-page":"2576","DOI":"10.1210\/en.2011-1600","article-title":"Dietary vitamin D\u2083 and 1,25-dihydroxyvitamin D\u2083 (calcitriol) exhibit equivalent anticancer activity in mouse xenograft models of breast and prostate cancer","volume":"153","author":"Swami","year":"2012","journal-title":"Endocrinology"},{"key":"10.1016\/j.jsbmb.2018.04.009_bib0180","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/S0076-6879(02)46071-5","article-title":"Generation of HIV-1 derived lentiviral vectors","volume":"346","author":"Follenzi","year":"2002","journal-title":"Methods Enzymol."},{"issue":"12","key":"10.1016\/j.jsbmb.2018.04.009_bib0185","doi-asserted-by":"crossref","first-page":"956","DOI":"10.7326\/0003-4819-118-12-199306150-00008","article-title":"Fibrinogen as a cardiovascular risk factor: a meta-analysis and review of the literature","volume":"118","author":"Ernst","year":"1993","journal-title":"Ann. Intern. Med."},{"issue":"23","key":"10.1016\/j.jsbmb.2018.04.009_bib0190","doi-asserted-by":"crossref","first-page":"2749","DOI":"10.1161\/CIR.0b013e31821c7c64","article-title":"Nontraditional risk factors and biomarkers for cardiovascular disease: mechanistic, research, and clinical considerations for youth: a scientific statement from the American heart association","volume":"123","author":"Balagopal","year":"2011","journal-title":"Circulation"},{"issue":"22","key":"10.1016\/j.jsbmb.2018.04.009_bib0195","doi-asserted-by":"crossref","first-page":"14251","DOI":"10.1074\/jbc.272.22.14251","article-title":"Resistance of gammaA\/gamma\u2019 fibrin clots to fibrinolysis","volume":"272","author":"Falls","year":"1997","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.jsbmb.2018.04.009_bib0200","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1055\/s-0037-1613148","article-title":"Association of gammaA\/gamma\u2019 fibrinogen levels and coronary artery disease","volume":"88","author":"Lovely","year":"2002","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.jsbmb.2018.04.009_bib0205","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.jpeds.2013.01.004","article-title":"Obesity-related increased \u03b3\u2019 fibrinogen concentration in children and its reduction by a physical activity-based lifestyle intervention: a randomized controlled study","volume":"163","author":"Lovely","year":"2013","journal-title":"J. Pediatr."},{"issue":"1","key":"10.1016\/j.jsbmb.2018.04.009_bib0210","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1042\/CS20140462","article-title":"The serum protein fetuin-B is involved in the development of acute myocardial infarction","volume":"129","author":"Jung","year":"2015","journal-title":"Clin. Sci. (Lond.)"},{"issue":"3","key":"10.1016\/j.jsbmb.2018.04.009_bib0215","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1172\/JCI17202","article-title":"The serum protein alpha 2-Heremans-Schmid glycoprotein\/fetuin-A is a systemically acting inhibitor of ectopic calcification","volume":"112","author":"Schafer","year":"2003","journal-title":"J. Clin. Invest."},{"issue":"1","key":"10.1016\/j.jsbmb.2018.04.009_bib0220","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.atherosclerosis.2006.08.052","article-title":"Association of high alpha2-Heremans-Schmid glycoprotein\/fetuin concentration in serum and intima-media thickness in patients with atherosclerotic vascular disease and low bone mass","volume":"195","author":"Fiore","year":"2007","journal-title":"Atherosclerosis"},{"issue":"Pt 1","key":"10.1016\/j.jsbmb.2018.04.009_bib0225","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1042\/bj20030676","article-title":"Tissue distribution and activity testing suggest a similar but not identical function of fetuin-B and fetuin-A","volume":"376","author":"Denecke","year":"2003","journal-title":"Biochem. J."},{"issue":"4","key":"10.1016\/j.jsbmb.2018.04.009_bib0230","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1038\/oby.2006.71","article-title":"The human obesity gene map: the 2005 update","volume":"14","author":"Rankinen","year":"2006","journal-title":"Obesity (Silver Spring)"},{"issue":"23-24","key":"10.1016\/j.jsbmb.2018.04.009_bib0235","doi-asserted-by":"crossref","first-page":"4898","DOI":"10.1002\/pmic.200800295","article-title":"A versatile peptide pI calculator for phosphorylated and N-terminal acetylated peptides experimentally tested using peptide isoelectric focusing","volume":"8","author":"Gauci","year":"2008","journal-title":"Proteomics"},{"issue":"6","key":"10.1016\/j.jsbmb.2018.04.009_bib0240","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1016\/j.cmet.2015.09.023","article-title":"Fetuin B Is a secreted hepatocyte factor linking steatosis to impaired glucose metabolism","volume":"22","author":"Meex","year":"2015","journal-title":"Cell Metab."},{"key":"10.1016\/j.jsbmb.2018.04.009_bib0245","doi-asserted-by":"crossref","first-page":"4479","DOI":"10.1210\/jc.2008-1505","article-title":"Fetuin-A and its relation to metabolic syndrome and fatty liver disease in obese children before and after weight loss","volume":"93","author":"Reinehr","year":"2008","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"24","key":"10.1016\/j.jsbmb.2018.04.009_bib0250","doi-asserted-by":"crossref","first-page":"4386","DOI":"10.1002\/pmic.201000391","article-title":"Plasma proteome analysis in diet-induced obesity-prone and obesity-resistant rats","volume":"10","author":"Choi","year":"2010","journal-title":"Proteomics"},{"key":"10.1016\/j.jsbmb.2018.04.009_bib0255","doi-asserted-by":"crossref","DOI":"10.1007\/s10753-017-0610-9","article-title":"Adipose tissue inflammation and oxidative stress: the ameliorative effects of vitamin D","author":"Farhangi","year":"2017","journal-title":"Inflammation"},{"issue":"1","key":"10.1016\/j.jsbmb.2018.04.009_bib0260","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.pathophys.2017.01.003","article-title":"Vitamin D reduces high-fat diet induced weight gain and C-reactive protein, increases interleukin-10, and reduces CD86 and caspase-3","volume":"24","author":"Gomaa","year":"2017","journal-title":"Pathophysiology"},{"key":"10.1016\/j.jsbmb.2018.04.009_bib0265","doi-asserted-by":"crossref","first-page":"e371","DOI":"10.1542\/peds.2009-0213","article-title":"Vitamin D status and cardiometabolic risk factors in the United States adolescent population","volume":"124","author":"Reis","year":"2009","journal-title":"Pediatrics"},{"issue":"5","key":"10.1016\/j.jsbmb.2018.04.009_bib0270","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1136\/adc.2010.187591","article-title":"A cross-sectional study of vitamin D and insulin resistance in children","volume":"96","author":"Kelly","year":"2011","journal-title":"Arch. Dis. Child"},{"issue":"1","key":"10.1016\/j.jsbmb.2018.04.009_bib0275","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1210\/jc.2011-1507","article-title":"Vitamin D. Deficiency in obese children and its relationship to glucose Homeostasis","volume":"97","author":"Olson","year":"2012","journal-title":"J Clin. Endocrinol. Metab."},{"issue":"20","key":"10.1016\/j.jsbmb.2018.04.009_bib0280","doi-asserted-by":"crossref","first-page":"12826","DOI":"10.1016\/S0021-9258(18)90821-5","article-title":"Structure of the human gamma-fibrinogen gene. Alternate mRNA splicing near the 3\u2019 end of the gene produces gamma A and gamma B forms of gamma-fibrinogen","volume":"259","author":"Fornace","year":"1984","journal-title":"J. Biol. Chem."},{"issue":"12","key":"10.1016\/j.jsbmb.2018.04.009_bib0285","doi-asserted-by":"crossref","first-page":"2284","DOI":"10.1016\/j.bbapap.2014.09.021","article-title":"Simultaneous characterization of sequence polymorphisms, glycosylation and phosphorylation of fibrinogen in a direct analysis by LC-MS","volume":"1844","author":"Nagel","year":"2014","journal-title":"Biochim. Biophys. Acta"},{"issue":"1","key":"10.1016\/j.jsbmb.2018.04.009_bib0290","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.thromres.2012.09.017","article-title":"Differential regulation of fibrinogen \u03b3 chain splice isoforms by interleukin-6","volume":"131","author":"Rein-Smith","year":"2013","journal-title":"Thromb. Res."},{"issue":"3","key":"10.1016\/j.jsbmb.2018.04.009_bib0295","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1042\/BJ20070658","article-title":"The farnesoid X receptor induces fetuin-B gene expression in human hepatocytes","volume":"407","author":"Murakami","year":"2007","journal-title":"Biochem. J."},{"key":"10.1016\/j.jsbmb.2018.04.009_bib0300","doi-asserted-by":"crossref","first-page":"2911","DOI":"10.2741\/3422","article-title":"Type 3 cystatins; fetuins, kininogen and histidine-rich glycoprotein","volume":"14","author":"Lee","year":"2009","journal-title":"Front Biosci. (Landmark Ed.)"},{"issue":"22","key":"10.1016\/j.jsbmb.2018.04.009_bib0305","doi-asserted-by":"crossref","first-page":"19991","DOI":"10.1074\/jbc.M112234200","article-title":"Alpha 2-HS glycoprotein\/fetuin, a transforming growth factor-beta\/bone morphogenetic protein antagonist, regulates postnatal bone growth and remodeling","volume":"277","author":"Szweras","year":"2002","journal-title":"J. Biol. Chem."},{"issue":"3","key":"10.1016\/j.jsbmb.2018.04.009_bib0310","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1097\/00024382-200115030-00004","article-title":"Fetuin, a negative acute phase protein, attenuates TNF synthesis and the innate inflammatory response to carrageenan","volume":"15","author":"Ombrellino","year":"2001","journal-title":"Shock"},{"issue":"4","key":"10.1016\/j.jsbmb.2018.04.009_bib0315","doi-asserted-by":"crossref","first-page":"853","DOI":"10.2337\/diacare.29.04.06.dc05-1938","article-title":"Alpha2-Heremans-Schmid glycoprotein\/fetuin-A is associated with insulin resistance and fat accumulation in the liver in humans","volume":"29","author":"Stefan","year":"2006","journal-title":"Diabetes Care"},{"issue":"19","key":"10.1016\/j.jsbmb.2018.04.009_bib0320","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1001\/jama.2008.614","article-title":"Association of fetuin-A level and diabetes risk","volume":"300","author":"Stefan","year":"2008","journal-title":"JAMA"},{"key":"10.1016\/j.jsbmb.2018.04.009_bib0325","doi-asserted-by":"crossref","first-page":"30045","DOI":"10.1038\/srep30045","article-title":"Fetuin-B (FETUB): a plasma biomarker candidate related to the severity of lung function in COPD","volume":"6","author":"Diao","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jsbmb.2018.04.009_bib0330","article-title":"Increased serum levels of fetuin B in patients with coronary artery disease","volume":"doi","author":"Zhu","year":"2017","journal-title":"Endocrine"},{"issue":"12","key":"10.1016\/j.jsbmb.2018.04.009_bib0335","doi-asserted-by":"crossref","first-page":"5542","DOI":"10.1210\/en.2006-0946","article-title":"Minireview: vitamin D receptor: new assignments for an already busy receptor","volume":"147","author":"Norman","year":"2006","journal-title":"Endocrinology"},{"issue":"5","key":"10.1016\/j.jsbmb.2018.04.009_bib0340","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1053\/jhep.2003.50176","article-title":"The normal liver harbors the vitamin D nuclear receptor in nonparenchymal and biliary epithelial cells","volume":"37","author":"Gascon-Barr\u00e9","year":"2003","journal-title":"Hepatology"},{"issue":"3","key":"10.1016\/j.jsbmb.2018.04.009_bib0345","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/j.cbi.2010.01.008","article-title":"Enhanced steatosis by nuclear receptor ligands: a study in cultured human hepatocytes and hepatoma cells with a characterized nuclear receptor expression profile","volume":"184","author":"Moya","year":"2010","journal-title":"Chem. Biol. Interact."},{"issue":"4","key":"10.1016\/j.jsbmb.2018.04.009_bib0350","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.bbadis.2017.01.001","article-title":"Vitamin D in liver disease: current evidence and potential directions","volume":"1863","author":"Elangovan","year":"2017","journal-title":"Biochim. Biophys. Acta"},{"issue":"2","key":"10.1016\/j.jsbmb.2018.04.009_bib0355","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1101\/gad.10.2.142","article-title":"Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937","volume":"10","author":"Liu","year":"1996","journal-title":"Genes Dev."},{"issue":"17","key":"10.1016\/j.jsbmb.2018.04.009_bib0360","doi-asserted-by":"crossref","first-page":"8097","DOI":"10.1073\/pnas.89.17.8097","article-title":"Sequences in the human parathyroid hormone gene that bind the 1,25-dihydroxyvitamin D3 receptor and mediate transcriptional repression in response to 1,25-dihydroxyvitamin D3","volume":"89","author":"Demay","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"10","key":"10.1016\/j.jsbmb.2018.04.009_bib0365","doi-asserted-by":"crossref","first-page":"5789","DOI":"10.1128\/MCB.15.10.5789","article-title":"Transcriptional repression of the interleukin-2 gene by vitamin D3: direct inhibition of NFATp\/AP-1 complex formation by a nuclear hormone receptor","volume":"15","author":"Alroy","year":"1995","journal-title":"Mol. Cell. Biol."},{"issue":"6","key":"10.1016\/j.jsbmb.2018.04.009_bib0370","doi-asserted-by":"crossref","first-page":"4191","DOI":"10.1128\/MCB.19.6.4191","article-title":"A two-hit mechanism for vitamin D3-mediated transcriptional repression of the granulocyte-macrophage colony-stimulating factor gene: vitamin d receptor competes for DNA binding with NFAT1 and stabilizes c-Jun","volume":"19","author":"Towers","year":"1999","journal-title":"Mol. Cell. Biol."},{"issue":"21","key":"10.1016\/j.jsbmb.2018.04.009_bib0375","doi-asserted-by":"crossref","first-page":"35390","DOI":"10.18632\/oncotarget.15697","article-title":"Fine tuning of vitamin D receptor (VDR) activity by post-transcriptional and post-translational modifications","volume":"8","author":"Zenata","year":"2017","journal-title":"Oncotarget"},{"issue":"3","key":"10.1016\/j.jsbmb.2018.04.009_bib0380","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1111\/j.1349-7006.2008.01045.x","article-title":"Strategy and mechanism for the prevention of hepatocellular carcinoma: phosphorylated retinoid X receptor alpha is a critical target for hepatocellular carcinoma chemoprevention","volume":"100","author":"Shimizu","year":"2009","journal-title":"Cancer Sci."},{"issue":"16","key":"10.1016\/j.jsbmb.2018.04.009_bib0385","doi-asserted-by":"crossref","first-page":"11205","DOI":"10.1074\/jbc.M510343200","article-title":"Complex role of the vitamin D receptor and its ligand in adipogenesis in 3T3-L1 cells","volume":"281","author":"Blumberg","year":"2006","journal-title":"J. Biol. Chem."},{"issue":"5","key":"10.1016\/j.jsbmb.2018.04.009_bib0390","doi-asserted-by":"crossref","first-page":"E916","DOI":"10.1152\/ajpendo.00410.2005","article-title":"Molecular mechanism of 1,25-dihydroxyvitamin D3 inhibition of adipogenesis in 3T3-L1 cells","volume":"290","author":"Kong","year":"2006","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"issue":"12","key":"10.1016\/j.jsbmb.2018.04.009_bib0395","doi-asserted-by":"crossref","first-page":"e52171","DOI":"10.1371\/journal.pone.0052171","article-title":"25-hydroxyvitamin D\u2083 and 1,25-dihydroxyvitamin D\u2083 promote the differentiation of human subcutaneous preadipocytes","volume":"7","author":"Nimitphong","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jsbmb.2018.04.009_bib0400","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.abb.2017.01.002","article-title":"Vitamin D supplementation inhibits oxidative stress and upregulate SIRT1\/AMPK\/GLUT4 cascade in high glucose-treated 3T3L1 adipocytes and in adipose tissue of high fat diet-fed diabetic mice","volume":"615","author":"Manna","year":"2017","journal-title":"Arch. Biochem. Biophys."}],"container-title":["The Journal of Steroid Biochemistry and Molecular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960076017303783?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960076017303783?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T23:58:33Z","timestamp":1760745513000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960076017303783"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":80,"alternative-id":["S0960076017303783"],"URL":"https:\/\/doi.org\/10.1016\/j.jsbmb.2018.04.009","relation":{},"ISSN":["0960-0760"],"issn-type":[{"value":"0960-0760","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fetuin B links vitamin D deficiency and pediatric obesity: Direct negative regulation by vitamin D","name":"articletitle","label":"Article Title"},{"value":"The Journal of Steroid Biochemistry and Molecular Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jsbmb.2018.04.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}