{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T15:45:39Z","timestamp":1783093539374,"version":"3.54.6"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Steroid Biochemistry and Molecular Biology"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1016\/j.jsbmb.2018.09.011","type":"journal-article","created":{"date-parts":[[2018,9,22]],"date-time":"2018-09-22T12:30:13Z","timestamp":1537619413000},"page":"237-247","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"special_numbering":"C","title":["Chitosan-eurycomanone nanoformulation acts on steroidogenesis pathway genes to increase the reproduction rate in fish"],"prefix":"10.1016","volume":"185","author":[{"given":"Irfan Ahmad","family":"Bhat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irshad","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ishfaq Nazir","family":"Mir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raja Aadil Hussain","family":"Bhat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gireesh-Babu","family":"P","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mukunda","family":"Goswami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sundaray","family":"J.K.","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rupam","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.jsbmb.2018.09.011_bib0005","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1530\/REP-08-0069","article-title":"Effects of Kaempferiaparviflora extracts on reproductive parameters and spermatic blood flow in male rats","volume":"136","author":"Chaturapanich","year":"2008","journal-title":"Reproduction"},{"issue":"1","key":"10.1016\/j.jsbmb.2018.09.011_bib0010","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.apjr.2015.12.009","article-title":"Phytochemical screening and evaluation of anti-fertility activity of Dactyloctenium aegyptium in male albino rats","volume":"5","author":"Naik","year":"2016","journal-title":"Asian Pac. J Reprod."},{"key":"10.1016\/j.jsbmb.2018.09.011_bib0015","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/4076430","article-title":"Effects of Withania somnifera on reproductive system: a systematic review of the available evidence","author":"Nasimi-Doost-Azgomi","year":"2018","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.jsbmb.2018.09.011_bib0020","series-title":"Clinical Gynaecologic Endocrinology and Infertility","article-title":"Clinical gynecologic endocrinology and infertility: lippincott Williams wilkins","author":"Speroff","year":"2005"},{"issue":"4","key":"10.1016\/j.jsbmb.2018.09.011_bib0025","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1046\/j.1472-8206.2001.00038.x","article-title":"Aphrodisiac evaluation in non\u2010copulator male rats after chronic administration of Eurycoma longifolia Jack","volume":"15","author":"Ang","year":"2001","journal-title":"Fundam. Clin. Pharmacol."},{"issue":"3","key":"10.1016\/j.jsbmb.2018.09.011_bib0030","first-page":"213","article-title":"Effects of Terminalia catappa seeds on sexual behaviour and fertility of male rats","volume":"2","author":"Ratnasooriya","year":"2000","journal-title":"Asian J. Androl."},{"issue":"2\u20133","key":"10.1016\/j.jsbmb.2018.09.011_bib0035","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0378-8741(01)00195-7","article-title":"Lepidium meyenii Walp. improves sexual behaviour in male rats independently from its action on spontaneous locomotor activity","volume":"75","author":"Cicero","year":"2001","journal-title":"J. Ethnopharmacol."},{"issue":"2","key":"10.1016\/j.jsbmb.2018.09.011_bib0040","first-page":"6","article-title":"Changes in hormonal parameters secondary to intravenous administration of Tribulus terrestris extract in primates","volume":"12","author":"Gauthaman","year":"2002","journal-title":"Int. J. Impot. Res."},{"issue":"4","key":"10.1016\/j.jsbmb.2018.09.011_bib0045","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1111\/j.1745-7262.2005.00052.x","article-title":"Aphrodisiac potentials of the aqueous extract of Fadogia agrestis (Schweinf. Ex Hiern) stem in male albino rats","volume":"7","author":"Yakubu","year":"2005","journal-title":"Asian J. Androl."},{"issue":"7","key":"10.1016\/j.jsbmb.2018.09.011_bib0050","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.fitote.2010.04.006","article-title":"Tongkat Ali (Eurycoma longifolia Jack): a review on its ethnobotany and pharmacological importance","volume":"81","author":"Bhat","year":"2010","journal-title":"Fitoterapia"},{"key":"10.1016\/j.jsbmb.2018.09.011_bib0055","series-title":"A Dictionary of Malayan Medicine","year":"1977"},{"issue":"2","key":"10.1016\/j.jsbmb.2018.09.011_bib0060","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.jep.2009.08.021","article-title":"Influence of Eurycoma longifolia on the copulatory activity of sexually sluggish and impotent male rats","volume":"126","author":"Zanoli","year":"2009","journal-title":"J. Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.jsbmb.2018.09.011_bib0065","first-page":"53","article-title":"The effect of Eurycoma longifolia Jack (Tongkat Ali) on sexual behaviour and sperm quality in rats","volume":"2","author":"Noor","year":"2004","journal-title":"Malays. J. Pharm. Sci."},{"issue":"1","key":"10.1016\/j.jsbmb.2018.09.011_bib0070","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.jep.2013.06.023","article-title":"Eurycomanone, the major quassinoid in Eurycoma longifolia root extract increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis","volume":"149","author":"Low","year":"2013","journal-title":"J. Ethnopharmacol."},{"issue":"3","key":"10.1016\/j.jsbmb.2018.09.011_bib0075","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1016\/j.jep.2012.11.013","article-title":"Standardized quassinoid-rich Eurycoma longifolia extract improved spermatogenesis and fertility in male rats via the hypothalamic\u2013pituitary\u2013gonadal axis","volume":"145","author":"Low","year":"2013","journal-title":"J. Ethnopharmacol."},{"issue":"6","key":"10.1016\/j.jsbmb.2018.09.011_bib0080","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/j.jbiosc.2014.11.010","article-title":"Production of biomass and bioactive compounds from adventitious roots by optimization of culturing conditions of Eurycoma longifolia in balloon-type bubble bioreactor system","volume":"119","author":"Lulu","year":"2015","journal-title":"J. Biosci. Bioeng."},{"issue":"09","key":"10.1016\/j.jsbmb.2018.09.011_bib0085","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1055\/s-2005-871259","article-title":"Bioavailability and pharmacokinetic studies of eurycomanone from Eurycoma longifolia","volume":"71","author":"Low","year":"2005","journal-title":"Planta Med."},{"key":"10.1016\/j.jsbmb.2018.09.011_bib0090","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.rvsc.2016.03.022","article-title":"Expression analysis of Sox9 genes during annual reproductive cycles in gonads and after nanodelivery of LHRH in Clarias batrachus","volume":"106","author":"Bhat","year":"2016","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.jsbmb.2018.09.011_bib0095","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.domaniend.2016.01.005","article-title":"Molecular characterization of kisspeptin gene and effect of nano\u2013encapsulted kisspeptin-10 on reproductive maturation in Catla catla","volume":"56","author":"Rather","year":"2016","journal-title":"Domest. Anim. Endocrinol."},{"issue":"1","key":"10.1016\/j.jsbmb.2018.09.011_bib0100","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/(SICI)1097-4628(19970103)63:1<125::AID-APP13>3.0.CO;2-4","article-title":"Novel hydrophilic chitosan-polyethylene oxide nanoparticles as protein carrier","volume":"63","author":"Calvo","year":"1997","journal-title":"J. Appl. Polym. Sci."},{"issue":"1\u20132","key":"10.1016\/j.jsbmb.2018.09.011_bib0105","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.ijpharm.2013.07.034","article-title":"Chitosan nanoparticles: preparation, size evolution and stability","volume":"455","author":"Rampino","year":"2013","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.jsbmb.2018.09.011_bib0110","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/j.ijbiomac.2018.02.067","article-title":"Fabrication and characterization of chitosan conjugated eurycomanone nanoparticles: in vivo evaluation of the biodistribution and toxicity in fish","volume":"112","author":"Bhat","year":"2018","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.jsbmb.2018.09.011_bib0115","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.aquaculture.2017.08.030","article-title":"Toxicological evaluation and effective dose selection of eurycomanone, a quassinoid of Eurycoma longifolia plant in fishes","volume":"481","author":"Bhat","year":"2017","journal-title":"Aquaculture"},{"issue":"1","key":"10.1016\/j.jsbmb.2018.09.011_bib0120","first-page":"66","article-title":"Comparative evaluation of efficacy and cost of synthetic and non-synthetic hormones for artificial breeding of African catfish (Clarias gariepinus Burchell, 1822)","volume":"3","author":"Adebayo","year":"2008","journal-title":"J. Fish. Aquat. Sci."},{"key":"10.1016\/j.jsbmb.2018.09.011_bib0125","first-page":"51","article-title":"Induced spawning of spotted murrel (Channa punctatus) and catfish (Hetreopneustes fossilis) using human chorionic gonodotropin and synthetic hormone (ovaprim)","volume":"72","author":"Haniffa","year":"2002","journal-title":"Vet. Archiv."},{"key":"10.1016\/j.jsbmb.2018.09.011_bib0130","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2\u0394\u0394\u2212CT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.jsbmb.2018.09.011_bib0135","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1016\/j.ijbiomac.2017.06.104","article-title":"Steroidogenic acute regulatory protein (StAR) gene expression construct: development, nanodelivery and effect on reproduction in air-breathing catfish, Clarias batrachus","volume":"104","author":"Rathor","year":"2017","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.jsbmb.2018.09.011_bib0140","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.anireprosci.2018.04.078","article-title":"Ameliorative effect of chitosan-conjugated 17\u03b1-methyltestosterone on testicular development in Clarias batrachus","volume":"193","author":"Saha","year":"2018","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.jsbmb.2018.09.011_bib0145","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.chemosphere.2016.12.066","article-title":"Oxidative and cellular metabolic stress of Oreochromis mossambicus as biomarkers indicators of trace element contaminants","volume":"171","author":"Kumar","year":"2017","journal-title":"Chemosphere"},{"key":"10.1016\/j.jsbmb.2018.09.011_bib0150","series-title":"Manual of Histologic Staining Methods of the Armed Forces Institute of Pathology","first-page":"38","author":"Luna","year":"1968"},{"issue":"2","key":"10.1016\/j.jsbmb.2018.09.011_bib0155","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1111\/j.1749-7345.1999.tb00872.x","article-title":"Induction and recovery from anesthesia in channel catfish Ictalurus punctatus fingerlings exposed to clove oil","volume":"30","author":"Waterstrat","year":"1999","journal-title":"J. World Aquacult. Soc."},{"issue":"3","key":"10.1016\/j.jsbmb.2018.09.011_bib0160","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1007\/s40011-015-0640-8","article-title":"Identification and expression analysis of thyroid stimulating hormone receptor (TSHR) in fish gonads following LHRH treatment","volume":"87","author":"Bhat","year":"2015","journal-title":"Proc. Natl. Proc. Natl. Acad. Sci. India Sect. B Biol. Sci."},{"issue":"3","key":"10.1016\/j.jsbmb.2018.09.011_bib0165","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1210\/edrv-9-3-295","article-title":"Molecular biology of steroid hormone synthesis","volume":"9","author":"Miller","year":"1988","journal-title":"Endocr. Rev."},{"issue":"9","key":"10.1016\/j.jsbmb.2018.09.011_bib0170","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1007\/s13258-017-0557-0","article-title":"R. Sharma Cloning, expression, molecular modelling and docking analysis of steroidogenic acute regulatory protein (StAR) in Clarias batrachus","volume":"39","author":"Bhat","year":"2017","journal-title":"Genes Genom."},{"key":"10.1016\/j.jsbmb.2018.09.011_bib0175","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.theriogenology.2017.09.017","article-title":"Characterization, molecular docking and expression of 3-beta-hydroxysteroid dehydrogenase during ontogenetic development and annual reproductive phases of gonads in Asian catfish (Clarias batrachus)","volume":"105","author":"Bhat","year":"2017","journal-title":"Theriogenology"},{"issue":"5","key":"10.1016\/j.jsbmb.2018.09.011_bib0180","first-page":"37","article-title":"Nutrients and botanicals for optimizing men\u2019s health. Examining the evidence for Eurycoma longifolia Jack, the Malaysian Ginseng in men\u2019s health","volume":"11","author":"Tambi","year":"2009","journal-title":"Asian J. Androl."},{"key":"10.1016\/j.jsbmb.2018.09.011_bib0185","first-page":"8","volume":"vol. 12","author":"Prakash","year":"2007"},{"issue":"2","key":"10.1016\/j.jsbmb.2018.09.011_bib0190","doi-asserted-by":"crossref","first-page":"181","DOI":"10.2147\/nano.2006.1.2.181","article-title":"Chitosan and lactic acid-grafted chitosan nanoparticles as carriers for prolonged drug delivery","volume":"1","author":"Bhattarai","year":"2006","journal-title":"Int. J. Nanomed."},{"issue":"23","key":"10.1016\/j.jsbmb.2018.09.011_bib0195","doi-asserted-by":"crossref","first-page":"3573","DOI":"10.1002\/smll.201200889","article-title":"Protein-polymer hybrid nanoparticles for drug delivery","volume":"8","author":"Ge","year":"2012","journal-title":"Small"},{"issue":"1","key":"10.1016\/j.jsbmb.2018.09.011_bib0200","doi-asserted-by":"crossref","first-page":"53302","DOI":"10.1371\/journal.pone.0053302","article-title":"Profiling of androgen response in rainbow trout pubertal testis: relevance to male gonad development and spermatogenesis","volume":"8","author":"Rolland","year":"2013","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.jsbmb.2018.09.011_bib0205","first-page":"388","article-title":"Mechanisms and clinical relevance of androgens and androgen receptor actions","volume":"26","author":"Kang","year":"2003","journal-title":"Chang Gung Med. J."},{"issue":"1","key":"10.1016\/j.jsbmb.2018.09.011_bib0210","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1111\/j.1439-0272.2011.01168.x","article-title":"Standardised water\u2010soluble extract of Eurycoma longifolia, Tongkatali, as testosterone booster for managing men with late\u2010onset hypogonadism","volume":"44","author":"Tambi","year":"2012","journal-title":"Andrologia"},{"issue":"12","key":"10.1016\/j.jsbmb.2018.09.011_bib0215","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1590\/S0100-879X1997001200017","article-title":"Plasma testosterone and 11-ketotestosterone levels of male pacu Piaractus mesopotamicus (Cypriniformes, Characidae)","volume":"30","author":"Gazola","year":"1997","journal-title":"Braz. J. Med. Biol. Res."},{"issue":"1","key":"10.1016\/j.jsbmb.2018.09.011_bib0220","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1093\/jb\/mvi098","article-title":"From SRY to SOX9: mammalian testis differentiation","volume":"138","author":"Kanai","year":"2005","journal-title":"J. Biochem."},{"issue":"2","key":"10.1016\/j.jsbmb.2018.09.011_bib0225","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.beem.2009.12.002","article-title":"Control of sex development","volume":"24","author":"Biason-Lauber","year":"2010","journal-title":"Best Pract. Res. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.jsbmb.2018.09.011_bib0230","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1385\/ENDO:26:3:207","article-title":"Mutations in human gonadotropin and gonadotropin receptor genes","volume":"26","author":"Huhtaniemi","year":"2005","journal-title":"Endocrine"},{"issue":"6","key":"10.1016\/j.jsbmb.2018.09.011_bib0235","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/j.bbamcr.2008.10.005","article-title":"Inositol trisphosphate and calcium signalling mechanisms","volume":"1793","author":"Berridge","year":"2009","journal-title":"Biochim. Biophys. Acta- Mol. Cell Res."},{"key":"10.1016\/j.jsbmb.2018.09.011_bib0240","series-title":"The Physiology of Reproduction","first-page":"189","article-title":"Mammalian fertilization","author":"Yanagimachi","year":"1994"},{"issue":"7077","key":"10.1016\/j.jsbmb.2018.09.011_bib0245","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1038\/nature04417","article-title":"Whole-cell patch-clamp measurements of spermatozoa reveal an alkaline-activated Ca2+ channel","volume":"439","author":"Kirichok","year":"2006","journal-title":"Nature"},{"issue":"5\u20136","key":"10.1016\/j.jsbmb.2018.09.011_bib0250","first-page":"595","article-title":"Sperm-activating peptides in the regulation of ion fluxes, signal transduction and motility","volume":"52","author":"Darszon","year":"2004","journal-title":"Int. J. Dev. Biol."},{"key":"10.1016\/j.jsbmb.2018.09.011_bib0255","series-title":"In Molecular Mechanisms in Spermatogenesis","first-page":"65","article-title":"Selenium, a key element in spermatogenesis and male fertility","author":"Boitani","year":"2009"},{"issue":"28","key":"10.1016\/j.jsbmb.2018.09.011_bib0260","doi-asserted-by":"crossref","first-page":"26491","DOI":"10.1074\/jbc.M503638200","article-title":"Mammalian selenoprotein thioredoxin-glutathione reductase roles in disulfide bond formation and sperm maturation","volume":"280","author":"Su","year":"2005","journal-title":"J. Biol. Chem."},{"issue":"5","key":"10.1016\/j.jsbmb.2018.09.011_bib0265","doi-asserted-by":"crossref","first-page":"1517S","DOI":"10.1093\/jn\/133.5.1517S","article-title":"Selenoprotein metabolism and function: evidence for more than one function for selenoprotein P, 2","volume":"133","author":"Burk","year":"2003","journal-title":"J. Nutr."},{"issue":"4","key":"10.1016\/j.jsbmb.2018.09.011_bib0270","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1538\/expanim.46.287","article-title":"Eurycoma longifolia Jack enhances libido in sexually experienced male rats","volume":"46","author":"Ang","year":"1997","journal-title":"Exp. Anim."},{"issue":"1","key":"10.1016\/j.jsbmb.2018.09.011_bib0275","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1590\/S1807-59322010000100014","article-title":"The effect of Eurycoma longifolia Jack on spermatogenesis in estrogen-treated rats","volume":"65","author":"Wahab","year":"2010","journal-title":"Clinics"},{"issue":"3","key":"10.1016\/j.jsbmb.2018.09.011_bib0280","first-page":"248","article-title":"Soelistyowati, Imron, Masculinization of tilapia Oreochromis niloticus using extract of pasakbumi plant Eurycoma longifolia through larval immersion","volume":"5","author":"Rinaldi","year":"2017","journal-title":"Int. J. Fish. Aquat. Stud."},{"issue":"1\u20134","key":"10.1016\/j.jsbmb.2018.09.011_bib0285","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/0044-8486(83)90413-1","article-title":"Sex control and manipulation in fish","volume":"33","author":"Yamazaki","year":"1983","journal-title":"Aquaculture"},{"key":"#cr-split#-10.1016\/j.jsbmb.2018.09.011_bib0290.1","unstructured":"E. Annie, F.L. Bradenton, Correcting systemic androgen levels using Eurycoma longifolia, 2007. United State Patent Application Pub. N0.: US 2007\/0009621 A1. Pharmaceutical patent attorneys, Llc"},{"key":"#cr-split#-10.1016\/j.jsbmb.2018.09.011_bib0290.2","unstructured":"(57) 55 Madison avenue Morristown, nj (2007) 079604397 (US)."},{"issue":"2","key":"10.1016\/j.jsbmb.2018.09.011_bib0295","first-page":"205","article-title":"In vitro characterization and delivery of chitosan-DNA microparticles into mammalian cells","volume":"7","author":"Dastan","year":"2004","journal-title":"J. Pharm. Pharm. Sci."}],"container-title":["The Journal of Steroid Biochemistry and Molecular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960076018304503?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960076018304503?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T00:00:20Z","timestamp":1760745620000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960076018304503"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":60,"alternative-id":["S0960076018304503"],"URL":"https:\/\/doi.org\/10.1016\/j.jsbmb.2018.09.011","relation":{},"ISSN":["0960-0760"],"issn-type":[{"value":"0960-0760","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chitosan-eurycomanone nanoformulation acts on steroidogenesis pathway genes to increase the reproduction rate in fish","name":"articletitle","label":"Article Title"},{"value":"The Journal of Steroid Biochemistry and Molecular Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jsbmb.2018.09.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}