{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T00:40:12Z","timestamp":1760748012903,"version":"build-2065373602"},"reference-count":74,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Steroid Biochemistry and Molecular Biology"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1016\/j.jsbmb.2022.106102","type":"journal-article","created":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T07:30:15Z","timestamp":1648711815000},"page":"106102","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Sex differences and heritability of adrenal steroidogenesis in offspring rats induced by prenatal nicotine exposure"],"prefix":"10.1016","volume":"221","author":[{"given":"Yawen","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fangfang","family":"Duan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lian","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guanghui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zheng","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hegui","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jsbmb.2022.106102_bib1","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1093\/ntr\/ntr280","article-title":"Prenatal cigarette smoke exposure and early initiation of multiple substance use","volume":"14","author":"Goldschmidt","year":"2012","journal-title":"Nicotine Tob Res."},{"key":"10.1016\/j.jsbmb.2022.106102_bib2","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1093\/ntr\/ntw228","article-title":"Maternal active smoking during pregnancy and low birth weight in the Americas: a systematic eeview and meta-analysis","volume":"19","author":"Pereira","year":"2017","journal-title":"Nicotine Tob Res."},{"key":"10.1016\/j.jsbmb.2022.106102_bib3","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.amepre.2010.03.009","article-title":"Infant morbidity and mortality attributable to prenatal smoking in the U.S","volume":"39","author":"Dietz","year":"2010","journal-title":"Am. J. Prev. Med."},{"key":"10.1016\/j.jsbmb.2022.106102_bib4","doi-asserted-by":"crossref","first-page":"395","DOI":"10.2105\/AJPH.90.3.395","article-title":"Maternal smoking and adverse birth outcomes among singletons and twins","volume":"90","author":"Pollack","year":"2000","journal-title":"Am. J. Public Health"},{"key":"10.1016\/j.jsbmb.2022.106102_bib5","doi-asserted-by":"crossref","DOI":"10.17269\/CJPH.107.5686","article-title":"Population attributable risk of smoking during pregnancy on obesity in offspring","volume":"107","author":"Chaiton","year":"2016","journal-title":"Can. J. Public Health"},{"key":"10.1016\/j.jsbmb.2022.106102_bib6","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1136\/bmj.324.7328.26","article-title":"Smoking during pregnancy and diabetes mellitus in a British longitudinal birth cohort","volume":"324","author":"Montgomery","year":"2002","journal-title":"BMJ."},{"key":"10.1016\/j.jsbmb.2022.106102_bib7","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1111\/j.1476-5381.2011.01488.x","article-title":"Maternal nicotine exposure and fetal programming of vascular oxidative stress in adult offspring","volume":"164","author":"Lim","year":"2011","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.jsbmb.2022.106102_bib8","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.toxlet.2012.01.006","article-title":"Nicotine-induced over-exposure to maternal glucocorticoid and activated glucocorticoid metabolism causes hypothalamic-pituitary-adrenal axis-associated neuroendocrine metabolic alterations in fetal rats","volume":"209","author":"Xu","year":"2012","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.jsbmb.2022.106102_bib9","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.toxlet.2012.09.001","article-title":"Prenatal nicotine exposure induced a hypothalamic-pituitary-adrenal axis-associated neuroendocrine metabolic programmed alteration in intrauterine growth retardation offspring rats","volume":"214","author":"Liu","year":"2012","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.jsbmb.2022.106102_bib10","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1111\/apha.12206","article-title":"Sex differences in the developmental programming of hypertension","volume":"210","author":"Ojeda","year":"2014","journal-title":"Acta Physiologica"},{"key":"10.1016\/j.jsbmb.2022.106102_bib11","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1042\/CS20150611","article-title":"Gender differences in developmental programming of cardiovascular diseases","volume":"130","author":"Dasinger","year":"2016","journal-title":"Clin. Sci."},{"key":"10.1016\/j.jsbmb.2022.106102_bib12","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1002\/hep.24097","article-title":"Gender-specific differences in adipose distribution and adipocytokines influence adolescent nonalcoholic fatty liver disease","volume":"53","author":"Ayonrinde","year":"2011","journal-title":"Hepatology"},{"key":"10.1016\/j.jsbmb.2022.106102_bib13","doi-asserted-by":"crossref","first-page":"4009","DOI":"10.1007\/s00018-019-03197-z","article-title":"Genomic imprinting and its effects on postnatal growth and adult metabolism","volume":"76","author":"Millership","year":"2019","journal-title":"Cell Mol. Life Sci."},{"key":"10.1016\/j.jsbmb.2022.106102_bib14","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1111\/j.1471-0528.2008.01822.x","article-title":"Transgenerational effects of prenatal exposure to the Dutch famine on neonatal adiposity and health in later life","volume":"115","author":"Painter","year":"2008","journal-title":"BJOG"},{"key":"10.1016\/j.jsbmb.2022.106102_bib15","doi-asserted-by":"crossref","first-page":"1648","DOI":"10.3945\/ajcn.2008.26140","article-title":"Prenatal exposure to the Dutch famine is associated with a preference for fatty foods and a more atherogenic lipid profile","volume":"88","author":"Lussana","year":"2008","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.jsbmb.2022.106102_bib16","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1038\/sj.ejhg.5200859","article-title":"Cardiovascular and diabetes mortality determined by nutrition during parents\u2019 and grandparents\u2019 slow growth period","volume":"10","author":"Kaati","year":"2002","journal-title":"Eur. J. Hum. Genet."},{"key":"10.1016\/j.jsbmb.2022.106102_bib17","doi-asserted-by":"crossref","first-page":"E1163","DOI":"10.1152\/ajpendo.00688.2013","article-title":"Maternal high-fat diet induces insulin resistance and deterioration of pancreatic \u03b2-cell function in adult offspring with sex differences in mice","volume":"306","author":"Yokomizo","year":"2014","journal-title":"Am. J. Physio. Endocrinol. Metab."},{"key":"10.1016\/j.jsbmb.2022.106102_bib18","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1017\/S204017441600074X","article-title":"Sex differences in early-life programming of the hypothalamic-pituitary-adrenal axis in humans suggest increased vulnerability in females: a systematic review","volume":"8","author":"Carpenter","year":"2017","journal-title":"J. Dev Orig. Health Dis."},{"key":"10.1016\/j.jsbmb.2022.106102_bib19","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1210\/jcem-66-2-422","article-title":"Expression of somatomedin\/insulin-like growth factor messenger ribonucleic acids in the human fetus: identification, characterization, and tissue distribution","volume":"66","author":"Han","year":"1988","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.jsbmb.2022.106102_bib20","first-page":"91","article-title":"IGF-I enhances cortisol secretion from guinea-pig adrenal gland: in vivo and in vitro study","volume":"20","author":"Raha","year":"2007","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.jsbmb.2022.106102_bib21","doi-asserted-by":"crossref","first-page":"8368","DOI":"10.1158\/0008-5472.CAN-06-4064","article-title":"Insulin-like growth factor-I, regulating aromatase expression through steroidogenic factor 1, supports estrogen-dependent tumor Leydig cell proliferation","volume":"67","author":"Sirianni","year":"2007","journal-title":"Cancer Res."},{"issue":"Suppl 2","key":"10.1016\/j.jsbmb.2022.106102_bib22","doi-asserted-by":"crossref","first-page":"e40","DOI":"10.1016\/j.placenta.2012.07.018","article-title":"The next generation of disease risk: are the effects of prenatal nutrition transmitted across generations? Evidence from animal and human studies","volume":"33","author":"Roseboom","year":"2012","journal-title":"Placenta"},{"key":"10.1016\/j.jsbmb.2022.106102_bib23","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.pbiomolbio.2015.03.002","article-title":"Multigenerational and transgenerational inheritance of drug exposure: the effects of alcohol, opiates, cocaine, marijuana, and nicotine","volume":"118","author":"Yohn","year":"2015","journal-title":"Prog. Biophys. Mol. Biol."},{"key":"10.1016\/j.jsbmb.2022.106102_bib24","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1289\/ehp.1205701","article-title":"Transgenerational inheritance of increased fat depot size, stem cell reprogramming, and hepatic steatosis elicited by prenatal exposure to the obesogen tributyltin in mice","volume":"121","author":"Chamorro-Garc\u00eda","year":"2013","journal-title":"Environ. Health Perspect"},{"key":"10.1016\/j.jsbmb.2022.106102_bib25","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s13072-020-00332-0","article-title":"Developmental nicotine exposure engenders intergenerational downregulation and aberrant posttranslational modification of cardinal epigenetic factors in the frontal cortices, striata, and hippocampi of adolescent mice","volume":"13","author":"Buck","year":"2020","journal-title":"Epigenetics Chromatin"},{"key":"10.1016\/j.jsbmb.2022.106102_bib26","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.taap.2018.03.018","article-title":"Prenatal nicotine exposure intergenerationally programs imperfect articular cartilage via histone deacetylation through maternal lineage","volume":"352","author":"Xie","year":"2018","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.jsbmb.2022.106102_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2019.111057","article-title":"Reduced testicular steroidogenesis in rat offspring by prenatal nicotine exposure: epigenetic programming and heritability via nAChR\/HDAC4","volume":"135","author":"Zhang","year":"2020","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.jsbmb.2022.106102_bib28","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.taap.2018.01.008","article-title":"IGF1\/MAPK\/ERK signaling pathway-mediated programming alterations of adrenal cortex cell proliferation by prenatal caffeine exposure in male offspring rats","volume":"341","author":"Chen","year":"2018","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.jsbmb.2022.106102_bib29","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1096\/fj.15-274399","article-title":"Intrauterine low-functional programming of IGF1 by prenatal nicotine exposure mediates the susceptibility to osteoarthritis in female adult rat offspring","volume":"30","author":"Tie","year":"2016","journal-title":"Faseb J."},{"key":"10.1016\/j.jsbmb.2022.106102_bib30","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.reprotox.2015.12.010","article-title":"Prenatal nicotine exposure induces poor articular cartilage quality in female adult offspring fed a high-fat diet and the intrauterine programming mechanisms","volume":"60","author":"Tie","year":"2016","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.jsbmb.2022.106102_bib31","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1097\/01.AOG.0000182580.78402.d2","article-title":"Maternal smoking and its association with birth weight","volume":"106","author":"Bernstein","year":"2005","journal-title":"Obstet Gynecol."},{"key":"10.1016\/j.jsbmb.2022.106102_bib32","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1111\/j.1365-3016.2007.00916.x","article-title":"Active and passive maternal smoking during pregnancy and the risks of low birthweight and preterm birth: the generation R study","volume":"22","author":"Jaddoe","year":"2008","journal-title":"Paediatr Perinat Epidemiol."},{"key":"10.1016\/j.jsbmb.2022.106102_bib33","first-page":"968","article-title":"Mitogenic action, regulation, and localization of insulin-like growth factors in the human fetal adrenal gland","volume":"76","author":"Mesiano","year":"1993","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.jsbmb.2022.106102_bib34","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1046\/j.1365-2443.1996.00254.x","article-title":"Identical origin of adrenal cortex and gonad revealed by expression profiles of Ad4BP\/SF-1","volume":"1","author":"Hatano","year":"1996","journal-title":"Genes Cells"},{"key":"10.1016\/j.jsbmb.2022.106102_bib35","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/S0022-3565(25)12693-1","article-title":"Intravenous nicotine replacement suppresses nicotine intake from cigarette smoking","volume":"254","author":"Benowitz","year":"1990","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.jsbmb.2022.106102_bib36","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1096\/fj.07-9574LSF","article-title":"Dose translation from animal to human studies revisited","volume":"22","author":"Reagan-Shaw","year":"2008","journal-title":"FASEB J"},{"key":"10.1016\/j.jsbmb.2022.106102_bib37","doi-asserted-by":"crossref","first-page":"314","DOI":"10.3389\/fpubh.2017.00314","article-title":"The effect of cigarette smoking during pregnancy on endocrine pancreatic function and fetal growth: a pilot study","volume":"5","author":"Lockhart","year":"2017","journal-title":"Front Public Health"},{"key":"10.1016\/j.jsbmb.2022.106102_bib38","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1002\/bdr2.1550","article-title":"Smoking and pregnancy: epigenetics and developmental origins of the metabolic syndrome","volume":"111","author":"Rogers","year":"2019","journal-title":"Birth Defects Res."},{"key":"10.1016\/j.jsbmb.2022.106102_bib39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.taap.2018.02.017","article-title":"nAChRs-ERK1\/2-Egr-1 signaling participates in the developmental toxicity of nicotine by epigenetically down-regulating placental 11beta-HSD2","volume":"344","author":"Zhou","year":"2018","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.jsbmb.2022.106102_bib40","doi-asserted-by":"crossref","first-page":"234","DOI":"10.24171\/j.phrp.2019.10.4.06","article-title":"Prenatal secondhand smoke exposure: correlation between nicotine in umbilical cord blood and neonatal anthropometry","volume":"10","author":"Ramadani","year":"2019","journal-title":"Osong Public Health Res. Perspect"},{"key":"10.1016\/j.jsbmb.2022.106102_bib41","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1038\/s41366-018-0238-3","article-title":"Fetal exposure to maternal active and secondhand smoking with offspring early-life growth in the Healthy Start study","volume":"43","author":"Moore","year":"2019","journal-title":"Int. J. Obes."},{"key":"10.1016\/j.jsbmb.2022.106102_bib42","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.fct.2019.03.055","article-title":"Decreased levels of H3K9ac and H3K27ac in the promotor region of ovarian P450 aromatase mediated low estradiol synthesis in female offspring rats induced by prenatal nicotine exposure as well as in human granulosa cells after nicotine treatment","volume":"128","author":"Fan","year":"2019","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.jsbmb.2022.106102_bib43","doi-asserted-by":"crossref","first-page":"3927","DOI":"10.1007\/s00204-017-1996-8","article-title":"Prenatal nicotine exposure induces HPA axis-hypersensitivity in offspring rats via the intrauterine programming of up-regulation of hippocampal GAD67","volume":"91","author":"He","year":"2017","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.jsbmb.2022.106102_bib44","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1093\/aje\/kwh128","article-title":"Paternal smoking and pregnancy loss: a prospective study using a biomarker of pregnancy","volume":"159","author":"Venners","year":"2004","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.jsbmb.2022.106102_bib45","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1093\/humrep\/deh898","article-title":"Effects of subfertility cause, smoking and body weight on the success rate of IVF","volume":"20","author":"Lintsen","year":"2005","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.jsbmb.2022.106102_bib46","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.atherosclerosis.2010.03.015","article-title":"Maternal smoking in pregnancy, adult adiposity and other risk factors for cardiovascular disease","volume":"211","author":"Power","year":"2010","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jsbmb.2022.106102_bib47","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1038\/oby.2009.354","article-title":"Prenatal exposure to maternal cigarette smoking and accumulation of intra-abdominal fat during adolescence","volume":"18","author":"Syme","year":"2010","journal-title":"Obesity (Silver Spring)"},{"key":"10.1016\/j.jsbmb.2022.106102_bib48","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.reprotox.2010.09.004","article-title":"Environmental toxicants and the developing immune system: a missing link in the global battle against infectious disease?","volume":"31","author":"Winans","year":"2011","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.jsbmb.2022.106102_bib49","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1001\/archgenpsychiatry.2012.1101","article-title":"Prenatal exposure to maternal cigarette smoking, amygdala volume, and fat intake in adolescence","volume":"70","author":"Haghighi","year":"2013","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.jsbmb.2022.106102_bib50","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.biopsych.2013.07.024","article-title":"Prenatal glucocorticoids and maternal smoking during pregnancy independently program adult nicotine dependence in daughters: a 40-year prospective study","volume":"75","author":"Stroud","year":"2014","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jsbmb.2022.106102_bib51","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1161\/HYPERTENSIONAHA.107.106203","article-title":"Prenatal gender-related nicotine exposure increases blood pressure response to angiotensin II in adult offspring","volume":"51","author":"Xiao","year":"2008","journal-title":"Hypertension"},{"key":"10.1016\/j.jsbmb.2022.106102_bib52","doi-asserted-by":"crossref","first-page":"12972","DOI":"10.1096\/fj.201901145RR","article-title":"Nicotine exposure during pregnancy programs osteopenia in male offspring rats via \u03b14\u03b22-nAChR-p300-ACE pathway","volume":"33","author":"Xiao","year":"2019","journal-title":"FASEB J."},{"key":"10.1016\/j.jsbmb.2022.106102_bib53","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.toxlet.2019.06.010","article-title":"Prenatal nicotine exposure increases osteoarthritis susceptibility in male elderly offspring rats via low-function programming of the TGF\u03b2 signaling pathway","volume":"314","author":"Chen","year":"2019","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.jsbmb.2022.106102_bib54","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1096\/fj.201800172R","article-title":"Two intrauterine programming mechanisms of adult hypercholesterolemia induced by prenatal nicotine exposure in male offspring rats","volume":"33","author":"Zhou","year":"2019","journal-title":"FASEB J."},{"key":"10.1016\/j.jsbmb.2022.106102_bib55","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1038\/nrendo.2014.74","article-title":"Glucocorticoids and fetal programming part 2: mechanisms","volume":"10","author":"Moisiadis","year":"2014","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.jsbmb.2022.106102_bib56","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1186\/1741-7015-10-129","article-title":"Perinatal nicotine exposure induces asthma in second generation offspring","volume":"10","author":"Rehan","year":"2012","journal-title":"BMC Med."},{"key":"10.1016\/j.jsbmb.2022.106102_bib57","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1002\/jnr.23878","article-title":"Sex-dependent effects of nicotine on the developing brain","volume":"95","author":"Cross","year":"2017","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.jsbmb.2022.106102_bib58","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1080\/10408444.2021.1977237","article-title":"Sexual dimorphism in placental development and its contribution to health and diseases","volume":"51","author":"Yu","year":"2021","journal-title":"Crit. Rev. Toxicol."},{"key":"10.1016\/j.jsbmb.2022.106102_bib59","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s13293-017-0138-6","article-title":"Sex differences in rat placental development: from pre-implantation to late gestation","volume":"8","author":"Kalisch-Smith","year":"2017","journal-title":"Biol. Sex Differ."},{"key":"10.1016\/j.jsbmb.2022.106102_bib60","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1038\/jp.2011.101","article-title":"Fetal sex-related dysregulation in testosterone production and their receptor expression in the human placenta with preeclampsia","volume":"32","author":"Sathishkumar","year":"2012","journal-title":"J. Perinatol."},{"issue":"Suppl 1","key":"10.1016\/j.jsbmb.2022.106102_bib61","doi-asserted-by":"crossref","first-page":"S50","DOI":"10.1016\/j.placenta.2014.11.018","article-title":"Review: endocrine regulation of placental phenotype","volume":"36","author":"Fowden","year":"2015","journal-title":"Placenta"},{"key":"10.1016\/j.jsbmb.2022.106102_bib62","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1038\/ijo.2017.159","article-title":"Obesity during pregnancy affects sex steroid concentrations depending on fetal gender","volume":"41","author":"Maliqueo","year":"2017","journal-title":"Int. J. Obes."},{"key":"10.1016\/j.jsbmb.2022.106102_bib63","doi-asserted-by":"crossref","first-page":"36805","DOI":"10.1038\/srep36805","article-title":"Maternal high estradiol exposure is associated with elevated thyroxine and Pax8 in mouse offspring","volume":"6","author":"Lv","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jsbmb.2022.106102_bib64","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1210\/en.2017-03017","article-title":"Prenatal high estradiol exposure induces sex-specific and dietarily reversible insulin resistance through decreased hypothalamic INSR","volume":"159","author":"Wang","year":"2018","journal-title":"Endocrinology"},{"key":"10.1016\/j.jsbmb.2022.106102_bib65","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2021.105942","article-title":"Sex difference in adrenal developmental toxicity induced by dexamethasone and its intrauterine programming mechanism","volume":"174","author":"Chen","year":"2021","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.jsbmb.2022.106102_bib66","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19051308","article-title":"Insulin-like growth factor (IGF) System in liver diseases","volume":"19","author":"Adamek","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jsbmb.2022.106102_bib67","doi-asserted-by":"crossref","first-page":"96","DOI":"10.15283\/ijsc.2012.5.2.96","article-title":"Effects of growth factors on establishment and propagation of embryonic stem cells from very early stage IVF embryos and their characterization in buffalo","volume":"5","author":"Puri","year":"2012","journal-title":"Int. J. Stem Cells"},{"key":"10.1016\/j.jsbmb.2022.106102_bib68","doi-asserted-by":"crossref","first-page":"2095","DOI":"10.1002\/stem.1478","article-title":"Insulin and IGFs enhance hepatocyte differentiation from human embryonic stem cells via the PI3K\/AKT pathway","volume":"31","author":"Magner","year":"2013","journal-title":"Stem Cells"},{"key":"10.1016\/j.jsbmb.2022.106102_bib69","doi-asserted-by":"crossref","first-page":"9746","DOI":"10.1074\/jbc.RA119.008759","article-title":"A distal super enhancer mediates estrogen-dependent mouse uterine-specific gene transcription of Igf1 (insulin-like growth factor 1)","volume":"294","author":"Hewitt","year":"2019","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jsbmb.2022.106102_bib70","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.jsbmb.2011.09.004","article-title":"Molecular mechanisms involved in the regulation of neuritogenesis by estradiol: recent advances","volume":"131","author":"Arevalo","year":"2012","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.jsbmb.2022.106102_bib71","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/sj.ejhg.5201538","article-title":"Sex-specific, male-line transgenerational responses in humans","volume":"14","author":"Pembrey","year":"2006","journal-title":"Eur. J. Hum. Genet."},{"key":"10.1016\/j.jsbmb.2022.106102_bib72","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.tem.2009.12.007","article-title":"Epigenetic transgenerational actions of environmental factors in disease etiology","volume":"21","author":"Skinner","year":"2010","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.jsbmb.2022.106102_bib73","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.taap.2015.09.024","article-title":"Ancestral TCDD exposure promotes epigenetic transgenerational inheritance of imprinted gene Igf2: methylation status and DNMTs","volume":"289","author":"Ma","year":"2015","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.jsbmb.2022.106102_bib74","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.148440","article-title":"H19\/let-7 axis mediates caffeine exposure during pregnancy induced adrenal dysfunction and its multi-generation inheritance","volume":"792","author":"He","year":"2021","journal-title":"Sci. Total Environ."}],"container-title":["The Journal of Steroid Biochemistry and Molecular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S096007602200053X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S096007602200053X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T00:09:04Z","timestamp":1760746144000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S096007602200053X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":74,"alternative-id":["S096007602200053X"],"URL":"https:\/\/doi.org\/10.1016\/j.jsbmb.2022.106102","relation":{},"ISSN":["0960-0760"],"issn-type":[{"type":"print","value":"0960-0760"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sex differences and heritability of adrenal steroidogenesis in offspring rats induced by prenatal nicotine exposure","name":"articletitle","label":"Article Title"},{"value":"The Journal of Steroid Biochemistry and Molecular Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jsbmb.2022.106102","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"106102"}}