{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T15:53:26Z","timestamp":1786377206337,"version":"build-2736575974"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T00:00:00Z","timestamp":1711584000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["PID2020-115019RB-I00"],"award-info":[{"award-number":["PID2020-115019RB-I00"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012619","name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red Fragilidad y Envejecimiento Saludable","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011033","name":"Agencia Estatal de Investigaci\u00f3n","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011033","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012352","name":"Universit\u00e0 degli Studi di Milano","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012352","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003407","name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Steroid Biochemistry and Molecular Biology"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.jsbmb.2024.106514","type":"journal-article","created":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T13:57:22Z","timestamp":1711634242000},"page":"106514","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Sex chromosome complement interacts with gonadal hormones in determining regional-specific neuroactive steroid levels in plasma, hippocampus, and hypothalamus. A study using the four core genotype mouse model"],"prefix":"10.1016","volume":"241","author":[{"given":"Lucia","family":"Cioffi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Grassi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Diviccaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donatella","family":"Caruso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Pinto-Benito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria-Angeles","family":"Arevalo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis Miguel","family":"Garcia-Segura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto Cosimo","family":"Melcangi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Giatti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jsbmb.2024.106514_bib1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.neubiorev.2015.09.023","article-title":"Levels and actions of neuroactive steroids in the nervous system under physiological and pathological conditions: sex-specific features","volume":"67","author":"Melcangi","year":"2016","journal-title":"Neurosci. Biobehav Rev."},{"key":"10.1016\/j.jsbmb.2024.106514_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.pneurobio.2018.06.007","article-title":"Neuroactive steroids, neurosteroidogenesis and sex","volume":"176","author":"Giatti","year":"2019","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.jsbmb.2024.106514_bib3","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1111\/j.1365-2826.2010.02064.x","article-title":"Effects of short- and long-term gonadectomy on neuroactive steroid levels in the central and peripheral nervous system of male and female rats","volume":"22","author":"Caruso","year":"2010","journal-title":"J. Neuroendocr."},{"key":"10.1016\/j.jsbmb.2024.106514_bib4","doi-asserted-by":"crossref","DOI":"10.1111\/jne.12736","article-title":"Sex differences in the brain expression of steroidogenic molecules under basal conditions and after gonadectomy","author":"Giatti","year":"2019","journal-title":"J. Neuroendocrinol:e12736"},{"key":"10.1016\/j.jsbmb.2024.106514_bib5","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.mce.2015.07.027","article-title":"Sex chromosome complement determines sex differences in aromatase expression and regulation in the stria terminalis and anterior amygdala of the developing mouse brain","volume":"414","author":"Cisternas","year":"2015","journal-title":"Mol. Cell Endocrinol."},{"key":"10.1016\/j.jsbmb.2024.106514_bib6","article-title":"Hormonal and genetic factors interact to control aromatase expression in the developing brain","author":"Cisternas","year":"2017","journal-title":"J. Neuroendocr."},{"issue":"1","key":"10.1016\/j.jsbmb.2024.106514_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.yfrne.2008.11.001","article-title":"What does the \"four core genotypes\" mouse model tell us about sex differences in the brain and other tissues?","volume":"30","author":"Arnold","year":"2009","journal-title":"Front. Neuroendocr."},{"issue":"3","key":"10.1016\/j.jsbmb.2024.106514_bib8","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1242\/dev.109.3.635","article-title":"XY female mice resulting from a heritable mutation in the primary testis-determining gene, Tdy","volume":"109","author":"Lovell-Badge","year":"1990","journal-title":"Development"},{"issue":"4","key":"10.1016\/j.jsbmb.2024.106514_bib9","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1093\/hmg\/7.4.715","article-title":"Mouse homologues of the human AZF candidate gene RBM are expressed in spermatogonia and spermatids, and map to a Y chromosome deletion interval associated with a high incidence of sperm abnormalities","volume":"7","author":"Mahadevaiah","year":"1998","journal-title":"Hum. Mol. Genet"},{"key":"10.1016\/j.jsbmb.2024.106514_bib10","doi-asserted-by":"crossref","first-page":"537","DOI":"10.3389\/fendo.2020.00537","article-title":"G protein-coupled estrogen receptor immunoreactivity fluctuates during the estrous cycle and show sex differences in the Amygdala and Dorsal Hippocampus","volume":"11","author":"Llorente","year":"2020","journal-title":"Front Endocrinol. (Lausanne)"},{"issue":"10","key":"10.1016\/j.jsbmb.2024.106514_bib11","doi-asserted-by":"crossref","first-page":"2278","DOI":"10.1016\/j.psyneuen.2013.04.016","article-title":"Comparison of plasma and cerebrospinal fluid levels of neuroactive steroids with their brain, spinal cord and peripheral nerve levels in male and female rats","volume":"38","author":"Caruso","year":"2013","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.jsbmb.2024.106514_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.yfrne.2019.100804","article-title":"Sex differences in steroid levels and steroidogenesis in the nervous system: physiopathological role","author":"Giatti","year":"2020","journal-title":"Front Neuroendocr."},{"key":"10.1016\/j.jsbmb.2024.106514_bib13","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.neuroscience.2011.05.054","article-title":"Neuroactive steroids in periphery and cerebrospinal fluid","volume":"191","author":"Kancheva","year":"2011","journal-title":"Neuroscience"},{"key":"10.1016\/j.jsbmb.2024.106514_bib14","doi-asserted-by":"crossref","unstructured":"Tukiainen T., Villani A.C., Yen A., Rivas M.A., Marshall J.L., Satija R., Aguirre M., Gauthier L., Fleharty M., Kirby A., Cummings B.B., Castel S.E., Karczewski K.J., Aguet F., Byrnes A., Consortium G.T., Laboratory DA, Coordinating Center -Analysis Working G, Statistical Methods groups-Analysis Working G, Enhancing Gg, Fund NIHC, Nih\/Nci, Nih\/Nhgri, Nih\/Nimh, Nih\/Nida, Biospecimen Collection Source Site N, Biospecimen Collection Source Site R, Biospecimen Core Resource V, Brain Bank Repository-University of Miami Brain Endowment B, Leidos Biomedical-Project M, Study E, Genome Browser Data I, Visualization EBI, Genome Browser Data I, Visualization-Ucsc Genomics Institute UoCSC, Lappalainen T, Regev A, Ardlie KG, Hacohen N, MacArthur DG (2017) Landscape of X chromosome inactivation across human tissues. Nature 550 (7675):244-248. doi:10.1038\/nature24265.","DOI":"10.1038\/nature24265"},{"key":"10.1016\/j.jsbmb.2024.106514_bib15","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2022.937875","article-title":"Epigenetic modifier Kdm6a\/Utx controls the specification of hypothalamic neuronal subtypes in a sex-dependent manner","volume":"10","author":"Cabrera Zapata","year":"2022","journal-title":"Front Cell Dev. Biol."},{"issue":"21-22","key":"10.1016\/j.jsbmb.2024.106514_bib16","doi-asserted-by":"crossref","first-page":"7043","DOI":"10.1007\/s00018-021-03945-0","article-title":"X-linked histone H3K27 demethylase Kdm6a regulates sexually dimorphic differentiation of hypothalamic neurons","volume":"78","author":"Cabrera Zapata","year":"2021","journal-title":"Cell Mol. Life Sci."},{"issue":"1","key":"10.1016\/j.jsbmb.2024.106514_bib17","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-46445-9","article-title":"High fat diet triggers a reduction in body fat mass in female mice deficient for Utx demethylase","volume":"9","author":"Ota","year":"2019","journal-title":"Sci. Rep."},{"issue":"3","key":"10.1016\/j.jsbmb.2024.106514_bib18","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1002\/ijc.32116","article-title":"The histone demethylase UTX\/KDM6A in cancer: Progress and puzzles","volume":"145","author":"Schulz","year":"2019","journal-title":"Int J. Cancer"},{"issue":"1","key":"10.1016\/j.jsbmb.2024.106514_bib19","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.gene.2013.07.052","article-title":"DAX1 regulatory networks unveil conserved and potentially new functions","volume":"530","author":"Martins","year":"2013","journal-title":"Gene"},{"issue":"11","key":"10.1016\/j.jsbmb.2024.106514_bib20","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1016\/j.metabol.2011.03.023","article-title":"Functional effects of DAX-1 mutations identified in patients with X-linked adrenal hypoplasia congenita","volume":"60","author":"Choi","year":"2011","journal-title":"Metabolism"},{"key":"10.1016\/j.jsbmb.2024.106514_bib21","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.compbiolchem.2017.02.009","article-title":"Comparative and evolutionary studies of mammalian arylsulfatase and sterylsulfatase genes and proteins encoded on the X-chromosome","volume":"68","author":"Holmes","year":"2017","journal-title":"Comput. Biol. Chem."},{"issue":"12","key":"10.1016\/j.jsbmb.2024.106514_bib22","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/S0168-9525(01)02446-5","article-title":"A high density of X-linked genes for general cognitive ability: a run-away process shaping human evolution?","volume":"17","author":"Zechner","year":"2001","journal-title":"Trends Genet"},{"key":"10.1016\/j.jsbmb.2024.106514_bib23","doi-asserted-by":"crossref","first-page":"63","DOI":"10.3389\/fnins.2012.00063","article-title":"Sex-specific modulation of gene expression networks in murine hypothalamus","volume":"6","author":"Mozhui","year":"2012","journal-title":"Front. Neurosci."},{"issue":"1","key":"10.1016\/j.jsbmb.2024.106514_bib24","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.brainres.2006.08.053","article-title":"High expression of the mammalian X chromosome in brain","volume":"1126","author":"Nguyen","year":"2006","journal-title":"Brain Res"},{"key":"10.1016\/j.jsbmb.2024.106514_bib25","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.brainres.2014.03.017","article-title":"Identification of sexually dimorphic genes in the neonatal mouse cortex and hippocampus","volume":"1562","author":"Armoskus","year":"2014","journal-title":"Brain Res"},{"issue":"20","key":"10.1016\/j.jsbmb.2024.106514_bib26","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232012288","article-title":"Genetics and Epigenetics of the X and Y chromosomes in the sexual differentiation of the brain","volume":"23","author":"Cabrera Zapata","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"33","key":"10.1016\/j.jsbmb.2024.106514_bib27","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2110416119","article-title":"Sex differences in the functional topography of association networks in youth","volume":"119","author":"Shanmugan","year":"2022","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"12","key":"10.1016\/j.jsbmb.2024.106514_bib28","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202201002RR","article-title":"UTX deficiency in neural stem\/progenitor cells results in impaired neural development, fetal ventriculomegaly, and postnatal death","volume":"36","author":"Koizumi","year":"2022","journal-title":"FASEB J."},{"issue":"6","key":"10.1016\/j.jsbmb.2024.106514_bib29","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1093\/gerona\/glad007","article-title":"X Chromosome Factor Kdm6a enhances cognition independent of its demethylase function in the aging XY Male Brain","volume":"78","author":"Shaw","year":"2023","journal-title":"J. Gerontol. A Biol. Sci. Med Sci."},{"issue":"23","key":"10.1016\/j.jsbmb.2024.106514_bib30","doi-asserted-by":"crossref","first-page":"11320","DOI":"10.1093\/cercor\/bhad368","article-title":"Molecular mechanisms underlying human spatial cognitive ability revealed with neurotransmitter and transcriptomic mapping","volume":"33","author":"Yang","year":"2023","journal-title":"Cereb. Cortex"},{"issue":"17","key":"10.1016\/j.jsbmb.2024.106514_bib31","doi-asserted-by":"crossref","first-page":"4521","DOI":"10.1523\/JNEUROSCI.5382-07.2008","article-title":"Sex-specific differences in expression of histone demethylases Utx and Uty in mouse brain and neurons","volume":"28","author":"Xu","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jsbmb.2024.106514_bib32","article-title":"Profiling of sexually dimorphic genes in neural cells to identify Eif2s3y, whose overexpression causes autism-like behaviors in male mice","volume":"9","author":"Zhang","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"issue":"1","key":"10.1016\/j.jsbmb.2024.106514_bib33","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-023-47977-x","article-title":"Developmental transcriptomic patterns can be altered by transgenic overexpression of Uty","volume":"13","author":"Rock","year":"2023","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.jsbmb.2024.106514_bib34","doi-asserted-by":"crossref","first-page":"2851","DOI":"10.1038\/s41467-019-10704-0","article-title":"Chromatin organization in the female mouse brain fluctuates across the oestrous cycle","volume":"10","author":"Jaric","year":"2019","journal-title":"Nat. Commun."},{"issue":"2","key":"10.1016\/j.jsbmb.2024.106514_bib35","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0212330","article-title":"Behavioural and psychiatric phenotypes in female carriers of genetic mutations associated with X-linked ichthyosis","volume":"14","author":"Cavenagh","year":"2019","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.jsbmb.2024.106514_bib36","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1002\/ajmg.a.61061","article-title":"De novo DDX3X missense variants in males appear viable and contribute to syndromic intellectual disability","volume":"179","author":"Nicola","year":"2019","journal-title":"Am. J. Med. Genet A"},{"issue":"1","key":"10.1016\/j.jsbmb.2024.106514_bib37","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/s41525-020-00162-9","article-title":"Missense variant contribution to USP9X-female syndrome","volume":"5","author":"Jolly","year":"2020","journal-title":"NPJ Genom. Med."},{"issue":"1","key":"10.1016\/j.jsbmb.2024.106514_bib38","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1186\/s12974-021-02120-3","article-title":"X chromosome escapee genes are involved in ischemic sexual dimorphism through epigenetic modification of inflammatory signals","volume":"18","author":"Qi","year":"2021","journal-title":"J. Neuroinflamm."},{"issue":"7","key":"10.1016\/j.jsbmb.2024.106514_bib39","doi-asserted-by":"crossref","DOI":"10.3390\/brainsci11070904","article-title":"The impact of X-chromosome inactivation on phenotypic expression of X-Linked neurodevelopmental disorders","volume":"11","author":"Brand","year":"2021","journal-title":"Brain Sci."},{"issue":"21","key":"10.1016\/j.jsbmb.2024.106514_bib40","doi-asserted-by":"crossref","first-page":"3913","DOI":"10.1016\/j.cell.2022.09.002","article-title":"X-linked ubiquitin-specific peptidase 11 increases tauopathy vulnerability in women","volume":"185","author":"Yan","year":"2022","journal-title":"Cell"},{"issue":"4","key":"10.1016\/j.jsbmb.2024.106514_bib41","doi-asserted-by":"crossref","DOI":"10.3390\/genes14040852","article-title":"Phenotypes and genotypes in patients with SMC1A-related developmental and epileptic encephalopathy","volume":"14","author":"Bozarth","year":"2023","journal-title":"Genes (Basel)"},{"issue":"9","key":"10.1016\/j.jsbmb.2024.106514_bib42","doi-asserted-by":"crossref","first-page":"2090","DOI":"10.1158\/2159-8290.CD-22-0869","article-title":"Sex-biased T-cell exhaustion drives differential immune responses in glioblastoma","volume":"13","author":"Lee","year":"2023","journal-title":"Cancer Discov."},{"key":"10.1016\/j.jsbmb.2024.106514_bib43","article-title":"An X chromosome transcriptome wide association study implicates ARMCX6 in Alzheimer's Disease","author":"Zhang","year":"2023","journal-title":"bioRxiv"},{"issue":"1","key":"10.1016\/j.jsbmb.2024.106514_bib44","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1186\/s12974-023-02936-1","article-title":"Inhibition of UTX\/KDM6A improves recovery of spinal cord injury by attenuating BSCB permeability and macrophage infiltration through the MLCK\/p-MLC pathway","volume":"20","author":"Xie","year":"2023","journal-title":"J. Neuroinflamm."},{"key":"10.1016\/j.jsbmb.2024.106514_bib45","article-title":"Decreased serum allopregnanolone and progesterone levels in male patients with bipolar disorder and their effects on cognitive functions","author":"Karademir","year":"2023","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"issue":"7-8","key":"10.1016\/j.jsbmb.2024.106514_bib46","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1089\/neu.2022.0111","article-title":"White matter microstructure is associated with serum neuroactive steroids and psychological functioning","volume":"40","author":"Umminger","year":"2023","journal-title":"J. Neurotrauma"},{"issue":"1","key":"10.1016\/j.jsbmb.2024.106514_bib47","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/jnc.15503","article-title":"Neurosteroids: a novel promise for the treatment of stroke and post-stroke complications","volume":"160","author":"Xu","year":"2022","journal-title":"J. Neurochem"},{"issue":"1","key":"10.1016\/j.jsbmb.2024.106514_bib48","first-page":"294","article-title":"Androgens and Parkinson's disease: a review of human studies and animal models","volume":"2","author":"Bourque","year":"2021","journal-title":"Androg. Clin. Res Ther."},{"key":"10.1016\/j.jsbmb.2024.106514_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2023.106169","article-title":"Disease stage-dependent changes in brain levels and neuroprotective effects of neuroactive steroids in Parkinson's disease","volume":"183","author":"Luchetti","year":"2023","journal-title":"Neurobiol. Dis."},{"issue":"6","key":"10.1016\/j.jsbmb.2024.106514_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2023.166757","article-title":"Downregulation of StAR driven neurosteroid biosynthesis as a distinctive feature in the brains of Alzheimer's disease patients","volume":"1869","author":"Manna","year":"2023","journal-title":"Biochim Biophys. Acta Mol. Basis Dis."}],"container-title":["The Journal of Steroid Biochemistry and Molecular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960076024000621?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960076024000621?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T01:35:00Z","timestamp":1777599300000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960076024000621"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":50,"alternative-id":["S0960076024000621"],"URL":"https:\/\/doi.org\/10.1016\/j.jsbmb.2024.106514","relation":{},"ISSN":["0960-0760"],"issn-type":[{"value":"0960-0760","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sex chromosome complement interacts with gonadal hormones in determining regional-specific neuroactive steroid levels in plasma, hippocampus, and hypothalamus. A study using the four core genotype mouse model","name":"articletitle","label":"Article Title"},{"value":"The Journal of Steroid Biochemistry and Molecular Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jsbmb.2024.106514","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"106514"}}