{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T11:41:41Z","timestamp":1762342901358,"version":"build-2065373602"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100017610","name":"Shenzhen Science and Technology Innovation Program","doi-asserted-by":"publisher","award":["JCYJ20220818103008017"],"award-info":[{"award-number":["JCYJ20220818103008017"]}],"id":[{"id":"10.13039\/501100017610","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Steroid Biochemistry and Molecular Biology"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.jsbmb.2025.106789","type":"journal-article","created":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T11:24:06Z","timestamp":1747826646000},"page":"106789","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Tea polyphenols and EGCG induce preeclampsia-like symptoms by reducing 2-methoxyestradiol"],"prefix":"10.1016","volume":"252","author":[{"given":"Yi","family":"Duan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chen","family":"Jin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaqi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0719-1175","authenticated-orcid":false,"given":"Pan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.jsbmb.2025.106789_bib1","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1161\/CIRCRESAHA.118.313276","article-title":"Preeclampsia","volume":"124","author":"Rana","year":"2019","journal-title":"Circ. Res."},{"issue":"1","key":"10.1016\/j.jsbmb.2025.106789_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ejogrb.2013.05.005","article-title":"Global and regional estimates of preeclampsia and eclampsia: a systematic review","volume":"170","author":"Abalos","year":"2013","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"issue":"5","key":"10.1016\/j.jsbmb.2025.106789_bib3","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.tjog.2017.08.004","article-title":"Preeclampsia: a review of the pathogenesis and possible management strategies based on its pathophysiological derangements","volume":"56","author":"El-Sayed","year":"2017","journal-title":"Taiwan. J. Obstet. Gynecol."},{"issue":"2","key":"10.1016\/j.jsbmb.2025.106789_bib4","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1097\/MNH.0000000000000105","article-title":"Pathogenesis of preeclampsia","volume":"24","author":"Sircar","year":"2015","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"issue":"2, ement","key":"10.1016\/j.jsbmb.2025.106789_bib5","doi-asserted-by":"crossref","first-page":"S1102","DOI":"10.1016\/j.ajog.2020.10.047","article-title":"The prediction of preeclampsia: the way forward","volume":"226","author":"Myatt","year":"2022","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.jsbmb.2025.106789_bib6","doi-asserted-by":"crossref","first-page":"l2381","DOI":"10.1136\/bmj.l2381","article-title":"Pre-eclampsia: pathophysiology and clinical implications","volume":"366","author":"Burton","year":"2019","journal-title":"BMJ"},{"issue":"12","key":"10.1016\/j.jsbmb.2025.106789_bib7","doi-asserted-by":"crossref","first-page":"3909","DOI":"10.3390\/molecules27123909","article-title":"Green tea (camellia sinensis): a review of its phytochemistry, pharmacology, and toxicology","volume":"27","author":"Zhao","year":"2022","journal-title":"Molecules"},{"issue":"4","key":"10.1016\/j.jsbmb.2025.106789_bib8","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1021\/acs.jafc.8b06146","article-title":"Recent advances in the Understanding of the Health Benefits and Molecular Mechanisms Associated with Green Tea polyphenols","volume":"67","author":"Xing","year":"2019","journal-title":"J. Agric. Food Chem."},{"issue":"2","key":"10.1016\/j.jsbmb.2025.106789_bib9","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.aninu.2020.01.001","article-title":"Antioxidant mechanism of tea polyphenols and its impact on health benefits","volume":"6","author":"Yan","year":"2020","journal-title":"Anim. Nutr."},{"issue":"2","key":"10.1016\/j.jsbmb.2025.106789_bib10","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.ijgo.2008.12.003","article-title":"Tea consumption during pregnancy and the risk of pre-eclampsia","volume":"105","author":"Wei","year":"2009","journal-title":"Int. J. Gynecol. Obstet."},{"key":"10.1016\/j.jsbmb.2025.106789_bib11","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.preghy.2022.08.002","article-title":"The association between maternal tea consumption and the risk of pregnancy induced hypertension: a retrospective cohort study in Lanzhou, China","volume":"30","author":"Li","year":"2022","journal-title":"Pregnancy Hypertens."},{"issue":"2","key":"10.1016\/j.jsbmb.2025.106789_bib12","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.phrs.2011.02.007","article-title":"The chemistry and biotransformation of tea constituents","volume":"64","author":"Sang","year":"2011","journal-title":"Pharmacol. Res."},{"issue":"4","key":"10.1016\/j.jsbmb.2025.106789_bib13","doi-asserted-by":"crossref","first-page":"31","DOI":"10.3390\/proteomes11040031","article-title":"A proteomics-based identification of the biological networks mediating the impact of epigallocatechin-3-gallate on trophoblast cell migration and invasion, with potential implications for maternal and fetal health","volume":"11","author":"Chen","year":"2023","journal-title":"Proteomes"},{"issue":"2","key":"10.1016\/j.jsbmb.2025.106789_bib14","doi-asserted-by":"crossref","first-page":"C308","DOI":"10.1152\/ajpcell.00003.2016","article-title":"Green tea (\u2212)-epigallocatechin gallate inhibits the growth of human villous trophoblasts via the ERK, p38, AMP-activated protein kinase, and protein kinase B pathways","volume":"311","author":"Shih","year":"2016","journal-title":"Am. J. Physiol. -Cell Physiol."},{"issue":"9","key":"10.1016\/j.jsbmb.2025.106789_bib15","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1016\/S0090-9556(24)15181-1","article-title":"O-methylation of tea polyphenols catalyzed by human placental cytosolic catechol-O-methyltransferase","volume":"28","author":"Zhu","year":"2000","journal-title":"Drug Metab. Dispos."},{"issue":"5","key":"10.1016\/j.jsbmb.2025.106789_bib16","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1124\/dmd.32.5.497","article-title":"Strong inhibitory effects of common tea catechins and bioflavonoids on the O-methylation of catechol estrogens catalyzed by human liver cytosolic catechol-O-methyltransferase","volume":"32","author":"Nagai","year":"2004","journal-title":"Drug Metab. Dispos."},{"issue":"10","key":"10.1016\/j.jsbmb.2025.106789_bib17","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0007356","article-title":"Catechol-O-methyltransferase expression and 2-methoxyestradiol affect microtubule dynamics and modify steroid receptor signaling in leiomyoma cells","volume":"4","author":"Salama","year":"2009","journal-title":"PLOS One"},{"issue":"2","key":"10.1016\/j.jsbmb.2025.106789_bib18","first-page":"282","article-title":"Concentrations of 2-methoxyoestrogens in human serum measured by a heterologous immunoassay with an 125I-labelled ligand","volume":"103","author":"Berg","year":"1983","journal-title":"Acta Endocrinol."},{"issue":"1","key":"10.1016\/j.jsbmb.2025.106789_bib19","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.fertnstert.2015.09.019","article-title":"Fetal Val108\/158Met catechol-O-methyltransferase (COMT) polymorphism and placental COMT activity are associated with the development of preeclampsia","volume":"105","author":"Pertegal","year":"2016","journal-title":"Fertil. Steril."},{"issue":"1-2","key":"10.1016\/j.jsbmb.2025.106789_bib20","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.chroma.2006.07.059","article-title":"High-throughput analysis of catechins and theaflavins by high performance liquid chromatography with diode array detection","volume":"1132","author":"Neilson","year":"2006","journal-title":"J. Chromatogr. A"},{"issue":"3","key":"10.1016\/j.jsbmb.2025.106789_bib21","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1111\/birt.12285","article-title":"Does tea consumption during early pregnancy have an adverse effect on birth outcomes?","volume":"44","author":"Lu","year":"2017","journal-title":"Birth"},{"issue":"3","key":"10.1016\/j.jsbmb.2025.106789_bib22","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/j.clnu.2015.05.003","article-title":"Therapeutic effect of high-dose green tea extract on weight reduction: a randomized, double-blind, placebo-controlled clinical trial","volume":"35","author":"Chen","year":"2016","journal-title":"Clin. Nutr."},{"issue":"7198","key":"10.1016\/j.jsbmb.2025.106789_bib23","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1038\/nature06951","article-title":"Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia","volume":"453","author":"Kanasaki","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.jsbmb.2025.106789_bib24","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.toxlet.2022.12.002","article-title":"Chemical Stability and Bioactivity of tanshinone I, tanshinone IIA, cryptotanshinone and dihydrotanshinone in in vitro test systems","volume":"375","author":"Roth","year":"2023","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.jsbmb.2025.106789_bib25","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.aca.2011.10.058","article-title":"Analysis of multiplex endogenous estrogen metabolites in human urine using ultra-fast liquid chromatography-tandem mass spectrometry: a case study for breast cancer","volume":"711","author":"Huang","year":"2012","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.jsbmb.2025.106789_bib26","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.microc.2019.03.008","article-title":"Rapid quantification of human urinary estrogens and estrogen metabolites by HPLC mass spectrometry","volume":"147","author":"You","year":"2019","journal-title":"Microchem. J."},{"issue":"4","key":"10.1016\/j.jsbmb.2025.106789_bib27","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/s10456-006-9055-8","article-title":"Vascular endothelial growth factor receptor-1 (VEGFR-1\/Flt-1): a dual regulator for angiogenesis","volume":"9","author":"Shibuya","year":"2006","journal-title":"Angiogenesis"},{"issue":"1","key":"10.1016\/j.jsbmb.2025.106789_bib28","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1056\/NEJMoa1414838","article-title":"Predictive value of the sFlt-1:PlGF ratio in women with suspected preeclampsia","volume":"374","author":"Zeisler","year":"2016","journal-title":"N. Engl. J. Med."},{"issue":"14","key":"10.1016\/j.jsbmb.2025.106789_bib29","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1016\/j.jacc.2020.08.014","article-title":"Preeclampsia\u2014pathophysiology and clinical presentations: JACC state-of-the-art review","volume":"76","author":"Ives","year":"2020","journal-title":"J. Am. Coll. Cardiol."},{"issue":"10","key":"10.1016\/j.jsbmb.2025.106789_bib30","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1124\/dmd.110.033548","article-title":"O-methylation of catechol estrogens by human placental catechol-o-methyltransferase: interindividual differences in sensitivity to heat inactivation and to inhibition by dietary polyphenols","volume":"38","author":"Zhu","year":"2010","journal-title":"Drug Metab. Dispos."},{"issue":"21","key":"10.1016\/j.jsbmb.2025.106789_bib31","doi-asserted-by":"crossref","first-page":"8692","DOI":"10.1021\/jm500572b","article-title":"Medicinal chemistry of catechol O-methyltransferase (COMT) inhibitors and their therapeutic utility","volume":"57","author":"Kiss","year":"2014","journal-title":"J. Med Chem."},{"issue":"2","key":"10.1016\/j.jsbmb.2025.106789_bib32","doi-asserted-by":"crossref","first-page":"158","DOI":"10.3390\/antiox13020158","article-title":"EGCG, a Green tea compound, increases NO production and has antioxidant action in a static and shear stress in vitro model of preeclampsia","volume":"13","author":"Bertozzi-Matheus","year":"2024","journal-title":"Antioxidants"},{"key":"10.1016\/j.jsbmb.2025.106789_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.jri.2024.104263","article-title":"Epigallocatechin gallate (EGCG) alleviates inflammation and endothelial dysfunction and improves pregnancy outcomes in preeclampsia (PE)-like rats via eNOS\/Nrf2\/HO-1 pathway","volume":"164","author":"Xu","year":"2024","journal-title":"J. Reprod. Immunol."},{"issue":"2S","key":"10.1016\/j.jsbmb.2025.106789_bib34","doi-asserted-by":"crossref","first-page":"S886","DOI":"10.1016\/j.ajog.2020.09.039","article-title":"Decidualization resistance in the origin of preeclampsia","volume":"226","author":"Garrido-G\u00f3mez","year":"2022","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"7343","key":"10.1016\/j.jsbmb.2025.106789_bib35","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1038\/472298a","article-title":"Developmental biology: remarkable role for the placenta","volume":"472","author":"McKay","year":"2011","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.jsbmb.2025.106789_bib36","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.preghy.2012.01.001","article-title":"The placenta in preeclampsia","volume":"2","author":"Roberts","year":"2012","journal-title":"Pregnancy Hypertens.: Int. J. Women\u2019S. Cardiovasc. Health"},{"issue":"Spec","key":"10.1016\/j.jsbmb.2025.106789_bib37","first-page":"62","article-title":"Placental damages in preeclampsia \u2013 from ultrasound images to histopathological findings","volume":"8","author":"Predoi","year":"2015","journal-title":"J. Med Life"},{"issue":"6","key":"10.1016\/j.jsbmb.2025.106789_bib38","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1002\/jps.20594","article-title":"Pharmacokinetic studies of green tea catechins in maternal plasma and fetuses in rats","volume":"95","author":"Chu","year":"2006","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.jsbmb.2025.106789_bib39","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.redox.2013.12.022","article-title":"New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate","volume":"2","author":"Kim","year":"2014","journal-title":"Redox Biol."},{"issue":"11","key":"10.1016\/j.jsbmb.2025.106789_bib40","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.3390\/nu4111679","article-title":"Epigallocatechin gallate (EGCG) is the most effective cancer chemopreventive polyphenol in green tea","volume":"4","author":"Du","year":"2012","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.jsbmb.2025.106789_bib41","doi-asserted-by":"crossref","first-page":"39","DOI":"10.3390\/nu11010039","article-title":"Tea polyphenols in promotion of human health","volume":"11","author":"Khan","year":"2019","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.jsbmb.2025.106789_bib42","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/s41576-019-0169-4","article-title":"Mechanisms of early placental development in mouse and humans","volume":"21","author":"Hemberger","year":"2020","journal-title":"Nat. Rev. Genet."},{"issue":"2","key":"10.1016\/j.jsbmb.2025.106789_bib43","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1177\/1933719114537716","article-title":"2-Methoxyestradiol plasma levels are associated with clinical severity indices and biomarkers of preeclampsia","volume":"22","author":"Pertegal","year":"2015","journal-title":"Reprod. Sci."},{"issue":"11","key":"10.1016\/j.jsbmb.2025.106789_bib44","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1002\/pd.3954","article-title":"Low 2-methoxyestradiol levels at the first trimester of pregnancy are associated with the development of pre-eclampsia","volume":"32","author":"P\u00e9rez-Sep\u00falveda","year":"2012","journal-title":"Prenat. Diagn."},{"issue":"2","key":"10.1016\/j.jsbmb.2025.106789_bib45","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.placenta.2014.11.013","article-title":"2-Methoxyestradiol regulates VEGFR-2 and sFlt-1 expression in human placenta","volume":"36","author":"Lee","year":"2015","journal-title":"Placenta"},{"issue":"2","key":"10.1016\/j.jsbmb.2025.106789_bib46","doi-asserted-by":"crossref","first-page":"710","DOI":"10.2353\/ajpath.2010.090513","article-title":"Preeclampsia: 2-methoxyestradiol induces cytotrophoblast invasion and vascular development specifically under hypoxic conditions","volume":"176","author":"Lee","year":"2010","journal-title":"Am. J. Pathol."},{"issue":"10","key":"10.1016\/j.jsbmb.2025.106789_bib47","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1016\/j.bcp.2005.01.024","article-title":"Inhibition of human liver catechol-O-methyltransferase by tea catechins and their metabolites: structure-activity relationship and molecular-modeling studies","volume":"69","author":"Chen","year":"2005","journal-title":"Biochem Pharm."},{"issue":"5","key":"10.1016\/j.jsbmb.2025.106789_bib48","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1093\/biolre\/ioae111","article-title":"Coffee consumption during pregnancy increases the risk of preeclampsia in rats by inhibiting 2-methoxyestradiol production\u2020","volume":"111","author":"Chen","year":"2024","journal-title":"Biol. Reprod."},{"issue":"3","key":"10.1016\/j.jsbmb.2025.106789_bib49","doi-asserted-by":"crossref","first-page":"686","DOI":"10.3390\/ijms19030686","article-title":"Potential health benefits of olive oil and plant polyphenols","volume":"19","author":"Gorzynik-Debicka","year":"2018","journal-title":"Int J. Mol. Sci."},{"issue":"1-2","key":"10.1016\/j.jsbmb.2025.106789_bib50","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.jsbmb.2008.11.011","article-title":"Inhibition of human catechol-O-methyltransferase (COMT)-mediated O-methylation of catechol estrogens by major polyphenolic components present in coffee","volume":"113","author":"Zhu","year":"2009","journal-title":"J. Steroid Biochem Mol. Biol."},{"issue":"3","key":"10.1016\/j.jsbmb.2025.106789_bib51","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1016\/j.bbrc.2013.12.110","article-title":"Green tea epigallocatechin gallate binds to and inhibits respiratory complexes in swelling but not normal rat hepatic mitochondria","volume":"443","author":"Weng","year":"2014","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"4","key":"10.1016\/j.jsbmb.2025.106789_bib52","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1016\/j.bbagen.2013.10.034","article-title":"Role of AMPK-mediated adaptive responses in human cells with mitochondrial dysfunction to oxidative stress","volume":"1840","author":"Wu","year":"2014","journal-title":"Biochim. Et. Biophys. Acta (BBA) - Gen. Subj."},{"issue":"12","key":"10.1016\/j.jsbmb.2025.106789_bib53","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1017\/S0007114509991218","article-title":"Green tea (Camellia sinensis) catechins and vascular function","volume":"102","author":"Moore","year":"2009","journal-title":"Br. J. Nutr."},{"issue":"10","key":"10.1016\/j.jsbmb.2025.106789_bib54","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1002\/biot.201000214","article-title":"Metabolism of green tea catechins by the human small intestine","volume":"5","author":"Schantz","year":"2010","journal-title":"Biotechnol. J."},{"issue":"3","key":"10.1016\/j.jsbmb.2025.106789_bib55","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1136\/gutjnl-2019-319101","article-title":"Gut dysbiosis induces the development of pre-eclampsia through bacterial translocation","volume":"69","author":"Chen","year":"2020","journal-title":"Gut"}],"container-title":["The Journal of Steroid Biochemistry and Molecular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960076025001177?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960076025001177?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T11:38:01Z","timestamp":1762342681000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960076025001177"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":55,"alternative-id":["S0960076025001177"],"URL":"https:\/\/doi.org\/10.1016\/j.jsbmb.2025.106789","relation":{},"ISSN":["0960-0760"],"issn-type":[{"type":"print","value":"0960-0760"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Tea polyphenols and EGCG induce preeclampsia-like symptoms by reducing 2-methoxyestradiol","name":"articletitle","label":"Article Title"},{"value":"The Journal of Steroid Biochemistry and Molecular Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jsbmb.2025.106789","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"106789"}}