{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T11:09:26Z","timestamp":1779361766257,"version":"3.51.4"},"reference-count":155,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Steroid Biochemistry and Molecular Biology"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.jsbmb.2025.106868","type":"journal-article","created":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T03:59:59Z","timestamp":1758772799000},"page":"106868","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Potential contribution of oxysterols and cholestanol in the vascular inflammatory process occurring in patients with Behcet\u2019s disease"],"prefix":"10.1016","volume":"255","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8492-9604","authenticated-orcid":false,"given":"Meriam","family":"Messedi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wassim","family":"Guidara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Samadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatma","family":"Makni-Ayadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00e9rard","family":"Lizard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jsbmb.2025.106868_bib1","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/S0140-6736(23)02629-6","article-title":"Behcet's syndrome","volume":"403","author":"Emmi","year":"2024","journal-title":"Lancet"},{"key":"10.1016\/j.jsbmb.2025.106868_bib2","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1080\/1744666X.2024.2388693","article-title":"Beh\u00e7et disease: epidemiology, classification criteria and treatment modalities","volume":"20","author":"Fazaa","year":"2024","journal-title":"Expert Rev. Clin. Immunol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib3","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1038\/nrrheum.2018.3","article-title":"Beh\u00e7et syndrome: a contemporary view","volume":"14","author":"Yazici","year":"2018","journal-title":"Nat. Rev. Rheuma"},{"key":"10.1016\/j.jsbmb.2025.106868_bib4","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1080\/1744666X.2016.1205486","article-title":"Behcet's disease: epidemiology, clinical manifestations, and diagnosis","volume":"13","author":"Davatchi","year":"2017","journal-title":"Expert Rev. Clin. Immunol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib5","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1056\/NEJM199910213411707","article-title":"Behcet's disease","volume":"341","author":"Sakane","year":"1999","journal-title":"N. Engl. J. Med"},{"key":"10.1016\/j.jsbmb.2025.106868_bib6","author":"Behcet","year":"1937","journal-title":"Uber rezidiverende aphthose durch ein virus verursachte Geschwure am Mund, am Auge und an den Genitalien"},{"key":"10.1016\/j.jsbmb.2025.106868_bib7","unstructured":"Hippocrates, De morbis popularibus, in: C.D. Adams (Ed.)."},{"key":"10.1016\/j.jsbmb.2025.106868_bib8","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/s41584-022-00880-7","article-title":"Vascular Beh\u00e7et syndrome: from pathogenesis to treatment","volume":"19","author":"Bettiol","year":"2023","journal-title":"Nat. Rev. Rheuma"},{"key":"10.1016\/j.jsbmb.2025.106868_bib9","doi-asserted-by":"crossref","first-page":"493","DOI":"10.3349\/ymj.2023.0578","article-title":"Cardiovascular manifestations in Beh\u00e7et's disease","volume":"65","author":"Kim","year":"2024","journal-title":"Yonsei Med. J."},{"key":"10.1016\/j.jsbmb.2025.106868_bib10","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1007\/s10067-021-06027-5","article-title":"Mortality associated with Beh\u00e7et's disease in France assessed by multiple-cause-of-death analysis","volume":"41","author":"David","year":"2022","journal-title":"Clin. Rheuma"},{"key":"10.1016\/j.jsbmb.2025.106868_bib11","first-page":"1964","article-title":"Clinical characteristics and predictors for cardiovascular system involvement in patients with behcet's disease","volume":"41","author":"Deng","year":"2023","journal-title":"Clin. Exp. Rheuma"},{"key":"10.1016\/j.jsbmb.2025.106868_bib12","first-page":"1497","article-title":"Ischaemic heart disease in behcet's syndrome: a systematic review and meta-analysis","volume":"40","author":"Yang","year":"2022","journal-title":"Clin. Exp. Rheuma"},{"key":"10.1016\/j.jsbmb.2025.106868_bib13","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.arcmed.2011.08.006","article-title":"Intima-media thickness of carotid artery in patients with behcet's disease","volume":"42","author":"Messedi","year":"2011","journal-title":"Arch. Med. Res."},{"key":"10.1016\/j.jsbmb.2025.106868_bib14","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1038\/s41572-019-0106-z","volume":"5","author":"Libby","year":"2019","journal-title":"Atheroscler. Nat. Rev. Dis. Prim."},{"key":"10.1016\/j.jsbmb.2025.106868_bib15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0021-9150(98)00196-8","article-title":"Oxysterols and atherosclerosis","volume":"142","author":"Brown","year":"1999","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jsbmb.2025.106868_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.jlr.2021.100165","article-title":"Cholesterol metabolism: from lipidomics to immunology","volume":"63","author":"Griffiths","year":"2022","journal-title":"J. Lipid Res"},{"key":"10.1016\/j.jsbmb.2025.106868_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2022.102882","article-title":"Sex-specific analysis in Beh\u00e7et's disease reveals higher genetic risk in Male patients","volume":"132","author":"Jo","year":"2022","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.jsbmb.2025.106868_bib18","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/978-3-030-92616-8_12","article-title":"The immunogenetics of behcet's disease","volume":"1367","author":"Y\u0131lmaz","year":"2022","journal-title":"Adv. Exp. Med Biol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib19","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1002\/art.41637","article-title":"Genetic association of a Gain-of-Function IFNGR1 polymorphism and the intergenic region LNCAROD\/DKK1 with Beh\u00e7et's disease","volume":"73","author":"Ortiz Fern\u00e1ndez","year":"2021","journal-title":"Arthritis Rheuma"},{"key":"10.1016\/j.jsbmb.2025.106868_bib20","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.3389\/fimmu.2019.01067","article-title":"Beh\u00e7et's disease: an overview of etiopathogenesis","volume":"10","author":"Leccese","year":"2019","journal-title":"Front Immunol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib21","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1007\/s00393-015-0036-4","article-title":"Association of cytokine gene polymorphisms (IL\u20116, IL\u201112B, IL\u201118) with behcet's disease: a meta-analysis","volume":"75","author":"Xu","year":"2016","journal-title":"Z. Rheuma"},{"key":"10.1016\/j.jsbmb.2025.106868_bib22","doi-asserted-by":"crossref","first-page":"665","DOI":"10.3389\/fimmu.2019.00665","article-title":"Immunopathogenesis of behcet's disease","volume":"10","author":"Tong","year":"2019","journal-title":"Front Immunol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib23","doi-asserted-by":"crossref","DOI":"10.3390\/ijms242216382","article-title":"Beh\u00e7et's disease: a comprehensive review on the role of HLA-B*51, antigen presentation, and inflammatory cascade","volume":"24","author":"Khoshbakht","year":"2023","journal-title":"Int J. Mol. Sci."},{"key":"10.1016\/j.jsbmb.2025.106868_bib24","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/0-306-48382-3_50","article-title":"Immunophenotype and Th1\/Th2 cytokines in patients with Adamantiades-Behcet's disease","volume":"528","author":"Psarra","year":"2003","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib25","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.jaci.2011.05.029","article-title":"Critical role of IL-21 in modulating TH17 and regulatory t cells in behcet disease","volume":"128","author":"Geri","year":"2011","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib26","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1111\/cei.12939","article-title":"Circulating NK cells and their subsets in Beh\u00e7et's disease","volume":"188","author":"Hasan","year":"2017","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib27","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s42358-023-00328-w","article-title":"The roles of immune cells in Beh\u00e7et\u2019s disease","volume":"63","author":"Hu","year":"2023","journal-title":"Adv. Rheumatol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib28","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/j.jhep.2020.05.004","article-title":"Glycolytic activation of monocytes regulates the accumulation and function of neutrophils in human hepatocellular carcinoma","volume":"73","author":"Peng","year":"2020","journal-title":"J. Hepatol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib29","article-title":"Neutrophil extracellular traps promote aberrant macrophages activation in Beh\u00e7et's disease","volume":"11","author":"Li","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib30","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.3389\/fimmu.2019.01085","article-title":"Beh\u00e7et's syndrome as a model of Thrombo-Inflammation: the role of neutrophils","volume":"10","author":"Emmi","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib31","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/s43556-024-00214-x","article-title":"Post-translational modifications of fibrinogen: implications for clotting, fibrin structure and degradation","volume":"5","author":"Nencini","year":"2024","journal-title":"Mol. Biomed."},{"key":"10.1016\/j.jsbmb.2025.106868_bib32","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1111\/cei.13243","article-title":"Behcet's syndrome as a tool to dissect the mechanisms of thrombo-inflammation: clinical and pathogenetic aspects","volume":"195","author":"Becatti","year":"2019","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib33","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1007\/s11239-022-02637-1","article-title":"Arterial and venous involvement in behcet's syndrome: a narrative review","volume":"54","author":"Toledo-Samaniego","year":"2022","journal-title":"J. Thromb. Thrombolysis"},{"key":"10.1016\/j.jsbmb.2025.106868_bib34","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/978-3-031-43883-7_11","article-title":"Oxysterols in vascular cells and role in atherosclerosis","volume":"1440","author":"Luquain-Costaz","year":"2024","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib35","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.freeradbiomed.2023.08.008","article-title":"When nitrosative stress hits the endoplasmic reticulum: possible implications in oxLDL\/oxysterols-induced endothelial dysfunction","volume":"208","author":"Nasoni","year":"2023","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.jsbmb.2025.106868_bib36","doi-asserted-by":"crossref","first-page":"223","DOI":"10.31083\/j.fbl2906223","article-title":"Endothelial cell dysfunction: onset, progression, and consequences","volume":"29","author":"Naderi-Meshkin","year":"2024","journal-title":"Front. Biosci. (Landmark Ed."},{"key":"10.1016\/j.jsbmb.2025.106868_bib37","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.785220","article-title":"Roles of macrophages in atherogenesis","volume":"12","author":"Farahi","year":"2021","journal-title":"Front. Pharm."},{"key":"10.1016\/j.jsbmb.2025.106868_bib38","doi-asserted-by":"crossref","first-page":"303","DOI":"10.2174\/1567205014666170505101426","article-title":"Lipid biomarkers in alzheimer's disease","volume":"15","author":"Zarrouk","year":"2018","journal-title":"Curr. Alzheimer Res."},{"key":"10.1016\/j.jsbmb.2025.106868_bib39","doi-asserted-by":"crossref","first-page":"R40","DOI":"10.1530\/REM-22-0005","article-title":"Sources of 7-ketocholesterol, metabolism and inactivation strategies: food and biomedical applications","volume":"2022","author":"Ghzaiel","year":"2022","journal-title":"Redox Exp. Med."},{"key":"10.1016\/j.jsbmb.2025.106868_bib40","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.plipres.2016.09.002","article-title":"Oxysterols: from cholesterol metabolites to key mediators","volume":"64","author":"Mutemberezi","year":"2016","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.jsbmb.2025.106868_bib41","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.mam.2009.02.005","article-title":"Oxysterols: sources, cellular storage and metabolism, and new insights into their roles in cholesterol homeostasis","volume":"30","author":"Brown","year":"2009","journal-title":"Mol. Asp. Med."},{"key":"10.1016\/j.jsbmb.2025.106868_bib42","doi-asserted-by":"crossref","DOI":"10.3390\/cells10092301","article-title":"Impact of oxysterols on cell death, proliferation, and differentiation induction: current status","volume":"10","author":"de Freitas","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.jsbmb.2025.106868_bib43","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.3389\/fnut.2022.853460","article-title":"Oxysterols as reliable markers of quality and safety in cholesterol containing food ingredients and products","volume":"9","author":"Canzoneri","year":"2022","journal-title":"Front. Nutr."},{"key":"10.1016\/j.jsbmb.2025.106868_bib44","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.freeradbiomed.2019.04.020","article-title":"Metabolism of Non-Enzymatically derived oxysterols: clues from sterol metabolic disorders","volume":"144","author":"Griffiths","year":"2019","journal-title":"Free Radic. Biol. Med"},{"key":"10.1016\/j.jsbmb.2025.106868_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.jlr.2023.100486","article-title":"25-Hydroxycholesterol in health and diseases","volume":"65","author":"Nguyen","year":"2024","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.jsbmb.2025.106868_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2019.101380","article-title":"7-Ketocholesterol in disease and aging","volume":"29","author":"Anderson","year":"2020","journal-title":"Redox Biol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib47","doi-asserted-by":"crossref","first-page":"110","DOI":"10.2174\/0929867327666200316142659","article-title":"A comprehensive review on oxysterols and related diseases","volume":"28","author":"Samadi","year":"2021","journal-title":"Curr. Med Chem."},{"key":"10.1016\/j.jsbmb.2025.106868_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.jsbmb.2019.105426","article-title":"Localisation of oxysterols at the sub-cellular level and in biological fluids","volume":"193","author":"Dias","year":"2019","journal-title":"J. Steroid Biochem Mol. Biol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib49","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1007\/978-3-031-43883-7_16","article-title":"Oxysterols as biomarkers of aging and disease","volume":"1440","author":"Dias","year":"2024","journal-title":"Adv. Exp. Med Biol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib50","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/978-3-031-43883-7_1","article-title":"The structure of oxysterols determines their behavior at phase boundaries: implications for model membranes and Structure-Activity relationships","volume":"1440","author":"Wn\u0119trzak","year":"2024","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib51","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/j.it.2024.09.013","article-title":"Cholesterol sensing and metabolic adaptation in tissue immunity","volume":"45","author":"Dang","year":"2024","journal-title":"Trends Immunol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib52","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/978-3-031-43883-7_12","article-title":"Implication of oxysterols and phytosterols in aging and human diseases","volume":"1440","author":"Vigne","year":"2024","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib53","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/978-3-031-43883-7_13","article-title":"Sterols in inflammatory diseases: implications and clinical utility","volume":"1440","author":"Yalcinkaya","year":"2024","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib54","doi-asserted-by":"crossref","DOI":"10.3390\/molecules30132883","article-title":"Oxysterol-Induced inflammation in human diseases: strategies for treatment with natural compounds and synthetic molecules","volume":"30","author":"Brahmi","year":"2025","journal-title":"Molecules"},{"key":"10.1016\/j.jsbmb.2025.106868_bib55","doi-asserted-by":"crossref","DOI":"10.3390\/cells10082078","article-title":"Multiple targets for oxysterols in their regulation of the immune system","volume":"10","author":"Reinmuth","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.jsbmb.2025.106868_bib56","doi-asserted-by":"crossref","first-page":"202","DOI":"10.2174\/1570159X20666220327215245","article-title":"Role of oxysterols in the activation of the NLRP3 inflammasome as a potential pharmacological approach in alzheimer's disease","volume":"21","author":"Martins","year":"2023","journal-title":"Curr. Neuropharmacol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib57","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.redox.2017.07.014","article-title":"Endothelial cells, endoplasmic reticulum stress and oxysterols","volume":"13","author":"Luchetti","year":"2017","journal-title":"Redox Biol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib58","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.arr.2014.09.006","article-title":"Involvement of oxysterols in age-related diseases and ageing processes","volume":"18","author":"Zarrouk","year":"2014","journal-title":"Ageing Res Rev."},{"key":"10.1016\/j.jsbmb.2025.106868_bib59","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.mam.2009.02.006","article-title":"Cytotoxic effects of oxysterols associated with human diseases: induction of cell death (apoptosis and\/or oncosis), oxidative and inflammatory activities, and phospholipidosis","volume":"30","author":"Vejux","year":"2009","journal-title":"Mol. Asp. Med."},{"key":"10.1016\/j.jsbmb.2025.106868_bib60","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.biochi.2019.09.020","article-title":"Phospholipid packing defects and oxysterols in atherosclerosis: dietary prevention and the French paradox","volume":"167","author":"Brown","year":"2019","journal-title":"Biochimie"},{"key":"10.1016\/j.jsbmb.2025.106868_bib61","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.arcmed.2011.05.001","article-title":"Atherogenic lipid profile in behcet's disease: evidence of alteration of HDL subclasses","volume":"42","author":"Messedi","year":"2011","journal-title":"Arch. Med. Res"},{"key":"10.1016\/j.jsbmb.2025.106868_bib62","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1111\/j.1346-8138.2007.00278.x","article-title":"Oxidative stress in patients with behcet's disease: I correlation with severity and clinical parameters","volume":"34","author":"Najim","year":"2007","journal-title":"J. Dermatol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib63","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.ejim.2008.08.001","article-title":"Oxidative stress: correlation with Beh\u00e7et's disease duration, activity and severity","volume":"19","author":"Harzallah","year":"2008","journal-title":"Eur. J. Intern Med."},{"key":"10.1016\/j.jsbmb.2025.106868_bib64","doi-asserted-by":"crossref","first-page":"217","DOI":"10.3109\/15569527.2011.554480","article-title":"Oxidative stress impairs endothelial nitric oxide levels in Beh\u00e7ets' disease","volume":"30","author":"Onur","year":"2011","journal-title":"Cutan. Ocul. Toxicol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib65","doi-asserted-by":"crossref","first-page":"13520","DOI":"10.1073\/pnas.1002922107","article-title":"Identification and pharmacological characterization of cholesterol-5,6-epoxide hydrolase as a target for tamoxifen and AEBS ligands","volume":"107","author":"de Medina","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jsbmb.2025.106868_bib66","doi-asserted-by":"crossref","DOI":"10.1155\/2011\/471947","article-title":"Contribution of cholesterol and oxysterols in the physiopathology of cataract: implication for the development of pharmacological treatments","volume":"2011","author":"Vejux","year":"2011","journal-title":"J. Ophthalmol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib67","doi-asserted-by":"crossref","DOI":"10.1016\/j.jsbmb.2022.106122","article-title":"Selected plasma oxysterols as a potential multi-marker biosignature panel for behcet's disease","volume":"221","author":"Messedi","year":"2022","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib68","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1194\/jlr.P048603","article-title":"On the formation of 7-ketocholesterol from 7-dehydrocholesterol in patients with CTX and SLO","volume":"55","author":"Bj\u00f6rkhem","year":"2014","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.jsbmb.2025.106868_bib69","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.freeradbiomed.2019.04.020","article-title":"Metabolism of non-enzymatically derived oxysterols: clues from sterol metabolic disorders","volume":"144","author":"Griffiths","year":"2019","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.jsbmb.2025.106868_bib70","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2019.113648","article-title":"G. Lizard, 7-Ketocholesterol and 7\u03b2-hydroxycholesterol: in vitro and animal models used to characterize their activities and to identify molecules preventing their toxicity","volume":"173","author":"Vejux","year":"2020","journal-title":"Biochem. Pharm."},{"key":"10.1016\/j.jsbmb.2025.106868_bib71","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.bcp.2013.02.002","article-title":"11\u03b2-Hydroxysteroid dehydrogenase type 1 contributes to the balance between 7-keto- and 7-hydroxy-oxysterols in vivo","volume":"86","author":"Miti\u0107","year":"2013","journal-title":"Biochem. Pharm."},{"key":"10.1016\/j.jsbmb.2025.106868_bib72","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1196\/annals.1367.012","article-title":"Tissue production of cortisol by 11beta-hydroxysteroid dehydrogenase type 1 and metabolic disease","volume":"1083","author":"Walker","year":"2006","journal-title":"Ann. N. Y Acad. Sci."},{"key":"10.1016\/j.jsbmb.2025.106868_bib73","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1007\/s00125-014-3228-6","article-title":"Tissue-specific dysregulation of cortisol regeneration by 11\u03b2HSD1 in obesity: has it promised too much?","volume":"57","author":"Stomby","year":"2014","journal-title":"Diabetologia"},{"key":"10.1016\/j.jsbmb.2025.106868_bib74","doi-asserted-by":"crossref","first-page":"3115","DOI":"10.1111\/bph.15173","article-title":"Oxiapoptophagy: a type of cell death induced by some oxysterols","volume":"178","author":"Nury","year":"2021","journal-title":"Br. J. Pharm."},{"key":"10.1016\/j.jsbmb.2025.106868_bib75","doi-asserted-by":"crossref","DOI":"10.3390\/cells11081251","article-title":"Effects of oxysterols on immune cells and related diseases","volume":"11","author":"de Freitas","year":"2022","journal-title":"Cells"},{"key":"10.1016\/j.jsbmb.2025.106868_bib76","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/0039-128X(90)90109-O","article-title":"Simultaneous quantification of several cholesterol autoxidation and monohydroxylation products by isotope-dilution mass spectrometry","volume":"55","author":"Breuer","year":"1990","journal-title":"Steroids"},{"key":"10.1016\/j.jsbmb.2025.106868_bib77","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/j.coph.2012.07.007","article-title":"Cholesterol epoxide hydrolase and cancer","volume":"12","author":"Silvente-Poirot","year":"2012","journal-title":"Curr. Opin. Pharm."},{"key":"10.1016\/j.jsbmb.2025.106868_bib78","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1152\/physrev.2000.80.1.361","article-title":"Jr., oxysterols: modulators of cholesterol metabolism and other processes","volume":"80","author":"Schroepfer","year":"2000","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.jsbmb.2025.106868_bib79","doi-asserted-by":"crossref","first-page":"18415","DOI":"10.1074\/jbc.M313615200","article-title":"Rapid hepatic metabolism of 7-Ketocholesterol by 11\u03b2-Hydroxysteroid dehydrogenase type 1: species-specific differences between the rat, human, and hamster enzyme","volume":"279","author":"Schweizer","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jsbmb.2025.106868_bib80","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.mce.2008.10.030","article-title":"Expression profiles of human 11beta-hydroxysteroid dehydrogenases type 1 and type 2 in inflammatory bowel diseases","volume":"301","author":"Stegk","year":"2009","journal-title":"Mol. Cell Endocrinol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib81","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1210\/jc.2008-1534","article-title":"Expression of 11beta-hydroxysteroid dehydrogenase type 1 in human fetal lung and regulation of its expression by interleukin-1beta and cortisol","volume":"94","author":"Yang","year":"2009","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.jsbmb.2025.106868_bib82","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/0021-9150(87)90111-0","article-title":"Action of cholestane-3 beta,5 alpha,6 beta-triol on rats with particular reference to the aorta","volume":"63","author":"Matthias","year":"1987","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jsbmb.2025.106868_bib83","doi-asserted-by":"crossref","DOI":"10.3390\/md22040174","article-title":"Cholestane-3\u03b2,5\u03b1,6\u03b2-triol induces multiple cell death in A549 cells via ER stress and autophagy activation","volume":"22","author":"Chen","year":"2024","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.jsbmb.2025.106868_bib84","doi-asserted-by":"crossref","first-page":"933","DOI":"10.33594\/000000186","article-title":"7-Keto-Cholesterol and Cholestan-3beta, 5alpha, 6beta-Triol induce eryptosis through distinct pathways leading to NADPH oxidase and nitric oxide synthase activation","volume":"53","author":"Attanzio","year":"2019","journal-title":"Cell Physiol. Biochem"},{"key":"10.1016\/j.jsbmb.2025.106868_bib85","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/0021-9150(87)90205-X","article-title":"Cholestan-3 beta,5 alpha,6 beta-triol decreases barrier function of cultured endothelial cell monolayers","volume":"68","author":"Hennig","year":"1987","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jsbmb.2025.106868_bib86","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1016\/j.cellbi.2007.02.009","article-title":"Endothelial cell and macrophage regulation of vascular smooth muscle cell calcification modulated by cholestane-3beta, 5alpha, 6beta-triol","volume":"31","author":"Liu","year":"2007","journal-title":"Cell Biol. Int."},{"key":"10.1016\/j.jsbmb.2025.106868_bib87","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s10565-005-0141-2","article-title":"Comparison of the cytotoxic, pro-oxidant and pro-inflammatory characteristics of different oxysterols","volume":"21","author":"Lemaire-Ewing","year":"2005","journal-title":"Cell Biol. Toxicol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib88","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1186\/s12974-024-03233-1","article-title":"25-hydroxycholesterol promotes brain cytokine production and leukocyte infiltration in a mouse model of lipopolysaccharide-induced neuroinflammation","volume":"21","author":"Romero","year":"2024","journal-title":"J. Neuroinflamm."},{"key":"10.1016\/j.jsbmb.2025.106868_bib89","doi-asserted-by":"crossref","DOI":"10.1016\/j.jlr.2023.100486","article-title":"25-Hydroxycholesterol in health and diseases","volume":"65","author":"Nguyen","year":"2024","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.jsbmb.2025.106868_bib90","doi-asserted-by":"crossref","DOI":"10.1242\/dmm.052145","article-title":"The role of 25-hydroxycholesterol in the pathophysiology of brain vessel dysfunction associated with infection and cholesterol dysregulation","volume":"18","author":"Tapia","year":"2025","journal-title":"Dis. Model Mech."},{"key":"10.1016\/j.jsbmb.2025.106868_bib91","doi-asserted-by":"crossref","first-page":"8893305","DOI":"10.1155\/2020\/8893305","article-title":"Multiple roles of 25-Hydroxycholesterol in lipid metabolism, antivirus process, inflammatory response, and cell survival","volume":"2020","author":"Cao","year":"2020","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.jsbmb.2025.106868_bib92","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.steroids.2015.02.022","article-title":"Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-\u03b3 in primary macrophages requires endogenous 25-hydroxycholesterol synthesis","volume":"99","author":"Lu","year":"2015","journal-title":"Steroids"},{"key":"10.1016\/j.jsbmb.2025.106868_bib93","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1016\/j.cell.2017.09.029","article-title":"Oxysterol restraint of cholesterol synthesis prevents AIM2 inflammasome activation","volume":"171","author":"Dang","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.jsbmb.2025.106868_bib94","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1684\/ecn.2018.0411","article-title":"Increased IL-1beta levels are associated with an imbalance of \"oxidant\/antioxidant\" status during behcet's disease","volume":"29","author":"Chekaoui","year":"2018","journal-title":"Eur. Cytokine Netw."},{"key":"10.1016\/j.jsbmb.2025.106868_bib95","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/s12950-015-0086-z","article-title":"Increased expression of the NLRP3 inflammasome components in patients with behcet's disease","volume":"12","author":"Kim","year":"2015","journal-title":"J. Inflamm. (Lond.)"},{"key":"10.1016\/j.jsbmb.2025.106868_bib96","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1093\/cvr\/cvac189","article-title":"Cholesterol accumulation in macrophages drives NETosis in atherosclerotic plaques via IL-1\u03b2 secretion","volume":"119","author":"Yalcinkaya","year":"2023","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.jsbmb.2025.106868_bib97","article-title":"Inflammatory mediators of endothelial dysfunction","volume":"13","author":"Dri","year":"2023","journal-title":"Life (Basel)"},{"key":"10.1016\/j.jsbmb.2025.106868_bib98","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1161\/CIRCRESAHA.117.312333","article-title":"Lysosomal cholesterol hydrolysis couples efferocytosis to Anti-Inflammatory oxysterol production","volume":"122","author":"Viaud","year":"2018","journal-title":"Circ. Res."},{"key":"10.1016\/j.jsbmb.2025.106868_bib99","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/sj.cdd.4400792","article-title":"Ceramide generation occurring during 7\u03b2-hydroxycholesterol- and 7-ketocholesterol-induced apoptosis is caspase independent and is not required to trigger cell death","volume":"8","author":"Miguet","year":"2001","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.jsbmb.2025.106868_bib100","first-page":"316","article-title":"Flow cytometry and spectral imaging multiphoton microscopy analysis of CD36 expression with quantum dots 605 of untreated and 7-ketocholesterol-treated human monocytic cells","volume":"28","author":"Kahn","year":"2006","journal-title":"Anal. Quant. Cytol. Histol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib101","doi-asserted-by":"crossref","first-page":"107","DOI":"10.4196\/kjpp.2024.28.2.107","article-title":"The role of 27-hydroxycholesterol in meta-inflammation","volume":"28","author":"Son","year":"2024","journal-title":"Korean J. Physiol. Pharm."},{"key":"10.1016\/j.jsbmb.2025.106868_bib102","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.redox.2012.12.001","article-title":"Oxysterols in the pathogenesis of major chronic diseases","volume":"1","author":"Poli","year":"2013","journal-title":"Redox Biol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib103","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbior.2021.100837","article-title":"Pathophysiological role of 27-hydroxycholesterol in human diseases","volume":"83","author":"Kim","year":"2022","journal-title":"Adv. Biol. Regul."},{"key":"10.1016\/j.jsbmb.2025.106868_bib104","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/S0021-9150(00)00473-1","article-title":"A potential role for sterol 27-hydroxylase in atherogenesis","volume":"154","author":"Shanahan","year":"2001","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jsbmb.2025.106868_bib105","doi-asserted-by":"crossref","first-page":"4101","DOI":"10.1038\/s41467-023-39586-z","article-title":"Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in Male mice","volume":"14","author":"Yu","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jsbmb.2025.106868_bib106","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.cmet.2014.05.013","article-title":"The cholesterol metabolite 27-hydroxycholesterol promotes atherosclerosis via proinflammatory processes mediated by estrogen receptor alpha","volume":"20","author":"Umetani","year":"2014","journal-title":"Cell Metab."},{"key":"10.1016\/j.jsbmb.2025.106868_bib107","doi-asserted-by":"crossref","DOI":"10.1210\/endocr\/bqab095","article-title":"The cholesterol metabolite 27HC increases secretion of extracellular vesicles which promote breast cancer progression","volume":"162","author":"Baek","year":"2021","journal-title":"Endocrinology"},{"key":"10.1016\/j.jsbmb.2025.106868_bib108","doi-asserted-by":"crossref","first-page":"4101","DOI":"10.1038\/s41467-023-39586-z","article-title":"Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in Male mice","volume":"14","author":"Yu","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jsbmb.2025.106868_bib109","doi-asserted-by":"crossref","first-page":"206","DOI":"10.3390\/biomedicines8070206","article-title":"NADPH oxidases and their role in atherosclerosis","volume":"8","author":"Poznyak","year":"2020","journal-title":"Biomedicines"},{"key":"10.1016\/j.jsbmb.2025.106868_bib110","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2019.01085","article-title":"Beh\u00e7et's syndrome as a model of Thrombo-Inflammation: the role of neutrophils","volume":"10","author":"Emmi","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib111","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.bbrc.2013.07.046","article-title":"Oxysterols induce transition of monocytic cells to phenotypically mature dendritic cell-like cells","volume":"438","author":"Son","year":"2013","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jsbmb.2025.106868_bib112","doi-asserted-by":"crossref","first-page":"3114","DOI":"10.1172\/JCI61758","article-title":"Dynamic t cell-APC interactions sustain chronic inflammation in atherosclerosis","volume":"122","author":"Koltsova","year":"2012","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.jsbmb.2025.106868_bib113","doi-asserted-by":"crossref","first-page":"2819","DOI":"10.1093\/rheumatology\/kead703","article-title":"Shelterin dysfunction promotes CD4+ t cell senescence in behcet's disease","volume":"63","author":"Shi","year":"2024","journal-title":"Rheumatol. (Oxf.)"},{"key":"10.1016\/j.jsbmb.2025.106868_bib114","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.jsbmb.2017.04.015","article-title":"27-Hydroxycholesterol upregulates the production of heat shock protein 60 of monocytic cells","volume":"172","author":"Kim","year":"2017","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib115","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/j.1365-2133.2006.07536.x","article-title":"Halim, the role of heat shock protein 60, vascular endothelial growth factor and antiphospholipid antibodies in behcet disease","volume":"156","author":"Shaker","year":"2007","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib116","doi-asserted-by":"crossref","first-page":"243","DOI":"10.3892\/br.2016.693","article-title":"Heat-shock protein 60 of porphyromonas gingivalis May induce dysfunction of human umbilical endothelial cells via regulation of endothelial-nitric oxide synthase and vascular endothelial-cadherin","volume":"5","author":"Wu","year":"2016","journal-title":"Biomed. Rep."},{"key":"10.1016\/j.jsbmb.2025.106868_bib117","doi-asserted-by":"crossref","first-page":"73","DOI":"10.3389\/fmolb.2020.00073","article-title":"Heat shock protein 60 in cardiovascular physiology and diseases","volume":"7","author":"Duan","year":"2020","journal-title":"Front. Mol. Biosci."},{"key":"10.1016\/j.jsbmb.2025.106868_bib118","doi-asserted-by":"crossref","first-page":"15352","DOI":"10.1038\/srep15352","article-title":"Heat shock protein 60 stimulates the migration of vascular smooth muscle cells via Toll-like receptor 4 and ERK MAPK activation","volume":"5","author":"Zhao","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jsbmb.2025.106868_bib119","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.neuro.2017.02.001","article-title":"27-Hydroxycholesterol regulates cholesterol synthesis and transport in C6 glioma cells","volume":"59","author":"An","year":"2017","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.jsbmb.2025.106868_bib120","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2021.114621","article-title":"Our evolving understanding of how 27-hydroxycholesterol influences cancer","volume":"196","author":"Ma","year":"2022","journal-title":"Biochem. Pharm."},{"key":"10.1016\/j.jsbmb.2025.106868_bib121","doi-asserted-by":"crossref","first-page":"111","DOI":"10.4196\/kjpp.2021.25.2.111","article-title":"27-Hydroxycholesterol induces macrophage gene expression via LXR-dependent and -independent mechanisms","volume":"25","author":"Kim","year":"2021","journal-title":"Korean J. Physiol. Pharm."},{"key":"10.1016\/j.jsbmb.2025.106868_bib122","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.atherosclerosis.2009.04.001","article-title":"LXR-activating oxysterols induce the expression of inflammatory markers in endothelial cells through LXR-independent mechanisms","volume":"207","author":"Morello","year":"2009","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jsbmb.2025.106868_bib123","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbior.2021.100837","article-title":"Pathophysiological role of 27-hydroxycholesterol in human diseases","volume":"83","author":"Kim","year":"2022","journal-title":"Adv. Biol. Regul."},{"key":"10.1016\/j.jsbmb.2025.106868_bib124","doi-asserted-by":"crossref","DOI":"10.1016\/j.plipres.2024.101304","article-title":"How active cholesterol coordinates cell cholesterol homeostasis: test of a hypothesis","volume":"96","author":"Lange","year":"2024","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.jsbmb.2025.106868_bib125","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/j.tem.2024.11.004","article-title":"Intracellular endothelial cell metabolism in vascular function and dysfunction","volume":"36","author":"Citrin","year":"2025","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.jsbmb.2025.106868_bib126","doi-asserted-by":"crossref","first-page":"e22","DOI":"10.1161\/ATVBAHA.119.312582","article-title":"Metabolic regulators of vascular inflammation","volume":"40","author":"Fairman","year":"2020","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib127","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2022.102733","article-title":"Hydroxylation site-specific and production-dependent effects of endogenous oxysterols on cholesterol homeostasis: implications for SREBP-2 and LXR","volume":"299","author":"Saito","year":"2023","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jsbmb.2025.106868_bib128","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1111\/jocd.15647","article-title":"Evaluation of pro-atherogenic lipid profile and high atherohenic indexes in patients with behcet's disease: a case-control study","volume":"22","author":"Acar","year":"2023","journal-title":"J. Cosmet. Dermatol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib129","doi-asserted-by":"crossref","DOI":"10.1016\/j.jsbmb.2022.106123","article-title":"Plasma oxysterols in drug-free patients with schizophrenia","volume":"221","author":"Guidara","year":"2022","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib130","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.cbi.2008.12.003","article-title":"Cholestane-3beta,5alpha,6beta-triol-induced reactive oxygen species production promotes mitochondrial dysfunction in isolated mice liver mitochondria","volume":"179","author":"Liu","year":"2009","journal-title":"Chem. Biol. Inter."},{"key":"10.1016\/j.jsbmb.2025.106868_bib131","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.redox.2018.05.010","article-title":"The role of autophagy in survival response induced by 27-hydroxycholesterol in human promonocytic cells","volume":"17","author":"Vurusaner","year":"2018","journal-title":"Redox Biol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib132","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.biochi.2012.02.029","article-title":"Five decades with oxysterols","volume":"95","author":"Bj\u00f6rkhem","year":"2013","journal-title":"Biochimie"},{"key":"10.1016\/j.jsbmb.2025.106868_bib133","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/S0168-8278(96)80165-6","article-title":"The metabolism of cholestanol in primary biliary cirrhosis","volume":"24","author":"Gylling","year":"1996","journal-title":"J. Hepatol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib134","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1159\/000201318","article-title":"Serum cholesterol, cholesterol precursors and plant sterols in different inflammatory bowel diseases","volume":"57","author":"Hakala","year":"1996","journal-title":"Digestion"},{"key":"10.1016\/j.jsbmb.2025.106868_bib135","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.3945\/ajcn.114.088781","article-title":"Serum plant sterols, cholestanol, and cholesterol precursors associate with histological liver injury in pediatric onset intestinal failure","volume":"100","author":"Mutanen","year":"2014","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.jsbmb.2025.106868_bib136","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1002\/hep.1840150519","article-title":"Serum and hepatic cholestanol, squalene and noncholesterol sterols in man: a study on liver transplantation","volume":"15","author":"Nikkil\u00e4","year":"1992","journal-title":"Hepatology"},{"key":"10.1016\/j.jsbmb.2025.106868_bib137","doi-asserted-by":"crossref","DOI":"10.1016\/j.disamonth.2023.101674","article-title":"Gastrointestinal Beh\u00e7et's disease: manifestations, diagnosis, and management","volume":"70","author":"Manuelyan","year":"2024","journal-title":"Dis. Mon."},{"key":"10.1016\/j.jsbmb.2025.106868_bib138","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1194\/jlr.M700027-JLR200","article-title":"On the mechanism of cerebral accumulation of cholestanol in patients with cerebrotendinous xanthomatosis","volume":"48","author":"Panzenboeck","year":"2007","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.jsbmb.2025.106868_bib139","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1089\/10966200360716634","article-title":"Cholestanol metabolism, molecular pathology, and nutritional implications","volume":"6","author":"Seyama","year":"2003","journal-title":"J. Med. Food"},{"key":"10.1016\/j.jsbmb.2025.106868_bib140","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24076426","article-title":"The role of cytokines in cholesterol accumulation in cells and atherosclerosis progression","volume":"24","author":"Markin","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jsbmb.2025.106868_bib141","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1093\/oxfordjournals.jbchem.a124061","article-title":"Gallstone formation in cholestanol-fed mice","volume":"113","author":"Kim","year":"1993","journal-title":"J. Biochem."},{"key":"10.1016\/j.jsbmb.2025.106868_bib142","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1161\/01.RES.69.1.216","article-title":"Excess membrane cholesterol alters calcium movements, cytosolic calcium levels, and membrane fluidity in arterial smooth muscle cells","volume":"69","author":"Gleason","year":"1991","journal-title":"Circ. Res."},{"key":"10.1016\/j.jsbmb.2025.106868_bib143","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.ajpath.2019.11.004","article-title":"Endothelial cell calcium signaling during barrier function and inflammation","volume":"190","author":"Dalal","year":"2020","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib144","doi-asserted-by":"crossref","first-page":"2217","DOI":"10.3390\/cimb44050150","article-title":"Calcium-permeable channels and endothelial dysfunction in acute lung injury","volume":"44","author":"Hao","year":"2022","journal-title":"Curr. Issues Mol. Biol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib145","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.ajpath.2019.11.004","article-title":"Endothelial cell calcium signaling during barrier function and inflammation","volume":"190","author":"Dalal","year":"2020","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib146","doi-asserted-by":"crossref","first-page":"3140","DOI":"10.1111\/bph.15311","article-title":"The oxysterol receptor GPR183 in inflammatory bowel diseases","volume":"178","author":"Misselwitz","year":"2021","journal-title":"Br. J. Pharm."},{"key":"10.1016\/j.jsbmb.2025.106868_bib147","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.biochi.2018.04.014","article-title":"EBI2 - sensor for dihydroxycholesterol gradients in neuroinflammation","volume":"153","author":"Kurschus","year":"2018","journal-title":"Biochimie"},{"key":"10.1016\/j.jsbmb.2025.106868_bib148","doi-asserted-by":"crossref","first-page":"29","DOI":"10.5152\/eurasianjmed.2022.22300","article-title":"Vitamin d in behcet's disease, a brief review of the literature","volume":"54","author":"Melikoglu","year":"2022","journal-title":"Eurasia J. Med"},{"key":"10.1016\/j.jsbmb.2025.106868_bib149","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s12876-021-01609-8","article-title":"Incidence and risk factors of micronutrient deficiency in patients with IBD and intestinal Beh\u00e7et's disease: folate, vitamin B12, 25-OH-vitamin D, and ferritin","volume":"21","author":"Park","year":"2021","journal-title":"BMC Gastroenterol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib150","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajo.2013.10.010","article-title":"Polymorphisms in genetics of vitamin d metabolism confer susceptibility to ocular Beh\u00e7et disease in a Chinese han population","volume":"157","author":"Fang","year":"2014","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib151","series-title":"Seattle Copyright \u00a9 1993-2025, University of Washington, Seattle. GeneReviews is a registered trademark of the University of Washington, Seattle. All rights reserved","article-title":"Smith-Lemli-Opitz syndrome","author":"Nowaczyk","year":"1993"},{"key":"10.1016\/j.jsbmb.2025.106868_bib152","first-page":"251","article-title":"Vitamin d and miRNA-155 in Beh\u00e7et\u2019s disease: possible association with the disease and disease activity","volume":"12","author":"Mohamed Mekawy","year":"2023","journal-title":"Rep. Biochem. Mol. Biol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib153","doi-asserted-by":"crossref","DOI":"10.1016\/j.jsbmb.2021.105996","article-title":"European network for oxysterol research (ENOR): 10 th anniversary","volume":"214","author":"Lizard","year":"2021","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.jsbmb.2025.106868_bib154","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2022.101615","article-title":"Oxysterols are potential physiological regulators of ageing","volume":"77","author":"de Medina","year":"2022","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.jsbmb.2025.106868_bib155","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/j.biochi.2012.08.007","article-title":"11\u03b2-Hydroxysteroid dehydrogenase type 1 contributes to the regulation of 7-oxysterol levels in the arterial wall through the inter-conversion of 7-ketocholesterol and 7\u03b2-hydroxycholesterol","volume":"95","author":"Miti\u0107","year":"2013","journal-title":"Biochimie"}],"container-title":["The Journal of Steroid Biochemistry and Molecular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960076025001967?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960076025001967?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T15:57:05Z","timestamp":1769702225000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960076025001967"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":155,"alternative-id":["S0960076025001967"],"URL":"https:\/\/doi.org\/10.1016\/j.jsbmb.2025.106868","relation":{},"ISSN":["0960-0760"],"issn-type":[{"value":"0960-0760","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Potential contribution of oxysterols and cholestanol in the vascular inflammatory process occurring in patients with Behcet\u2019s disease","name":"articletitle","label":"Article Title"},{"value":"The Journal of Steroid Biochemistry and Molecular Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jsbmb.2025.106868","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"106868"}}