{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T10:50:31Z","timestamp":1794567031522,"version":"4.9.1"},"reference-count":53,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,18]],"date-time":"2022-08-18T00:00:00Z","timestamp":1660780800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["jscai.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Society for Cardiovascular Angiography &amp; Interventions"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1016\/j.jscai.2022.100452","type":"journal-article","created":{"date-parts":[[2022,9,16]],"date-time":"2022-09-16T18:30:06Z","timestamp":1663353006000},"page":"100452","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"title":["Transcatheter Pulmonary Valve Replacement: A Review of Current Valve Technologies"],"prefix":"10.1016","volume":"1","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3298-4556","authenticated-orcid":false,"given":"Neil D.","family":"Patel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel S.","family":"Levi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John P.","family":"Cheatham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0964-0659","authenticated-orcid":false,"given":"Shakeel A.","family":"Qureshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shabana","family":"Shahanavaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evan M.","family":"Zahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9239","key":"10.1016\/j.jscai.2022.100452_bib1","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1016\/S0140-6736(00)02844-0","article-title":"Percutaneous replacement of pulmonary valve in a right-ventricle to pulmonary-artery prosthetic conduit with valve dysfunction","volume":"356","author":"Bonhoeffer","year":"2000","journal-title":"Lancet"},{"issue":"18","key":"10.1016\/j.jscai.2022.100452_bib2","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1016\/j.jacc.2009.06.034","article-title":"Implantation of the melody transcatheter pulmonary valve in patients with a dysfunctional right ventricular outflow tract conduit early results from the U.S. clinical trial","volume":"54","author":"Zahn","year":"2009","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"16","key":"10.1016\/j.jscai.2022.100452_bib3","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1016\/j.jcin.2018.05.051","article-title":"Safety and feasibility of melody transcatheter pulmonary valve replacement in the native right ventricular outflow tract: a multicenter pediatric heart network scholar study","volume":"11","author":"Martin","year":"2018","journal-title":"JACC Cardiovasc Interv"},{"issue":"5","key":"10.1016\/j.jscai.2022.100452_bib4","first-page":"816","article-title":"The Medtronic Melody\u00ae transcatheter pulmonary valve implanted at 24-mm diameter \u2013 it works","volume":"82","author":"Cheatham","year":"2013","journal-title":"Catheter Cardiovasc Interv"},{"issue":"2","key":"10.1016\/j.jscai.2022.100452_bib5","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1161\/CIRCINTERVENTIONS.113.000881","article-title":"Feasibility and short-term outcomes of percutaneous transcatheter pulmonary valve replacement in small (<30 kg) children with dysfunctional right ventricular outflow tract conduits","volume":"7","author":"Berman","year":"2014","journal-title":"Circ Cardiovasc Interv"},{"issue":"4","key":"10.1016\/j.jscai.2022.100452_bib6","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1007\/s00246-017-1574-0","article-title":"Preprocedural risk assessment prior to PPVI with CMR and cardiac CT","volume":"38","author":"Malone","year":"2017","journal-title":"Pediatr Cardiol"},{"issue":"9","key":"10.1016\/j.jscai.2022.100452_bib7","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/j.jcin.2022.02.047","article-title":"Cardiac magnetic resonance to predict coronary artery compression in transcatheter pulmonary valve implantation into conduits","volume":"15","author":"Romans","year":"2022","journal-title":"JACC Cardiovasc Interv"},{"issue":"5","key":"10.1016\/j.jscai.2022.100452_bib8","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1161\/CIRCINTERVENTIONS.113.000202","article-title":"Risk of coronary artery compression among patients referred for transcatheter pulmonary valve implantation: a multicenter experience","volume":"6","author":"Morray","year":"2013","journal-title":"Circ Cardiovasc Interv"},{"issue":"2","key":"10.1016\/j.jscai.2022.100452_bib9","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1111\/joic.12270","article-title":"Aortic root distortion and aortic insufficiency during balloon angioplasty of the right ventricular outflow tract prior to transcatheter pulmonary valve replacement","volume":"29","author":"Torres","year":"2016","journal-title":"J\u00a0Interv Cardiol"},{"issue":"12","key":"10.1016\/j.jscai.2022.100452_bib10","first-page":"E954","article-title":"Expanded use of the one-step technique for simultaneous landing zone stenting and placement of the melody transcatheter pulmonary valve","volume":"33","author":"Guyon","year":"2021","journal-title":"J\u00a0Invasive Cardiol"},{"issue":"1","key":"10.1016\/j.jscai.2022.100452_bib11","first-page":"64","article-title":"A\u00a0new one-step procedure for pulmonary valve implantation of the melody valve: simultaneous prestenting and valve implantation","volume":"91","author":"Boudjemline","year":"2018","journal-title":"Catheter Cardiovasc Interv"},{"issue":"4","key":"10.1016\/j.jscai.2022.100452_bib12","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1093\/ejcts\/ezaa410","article-title":"Procedural technique for hybrid pulmonary valve replacement in infants and small children","volume":"59","author":"Breatnach","year":"2021","journal-title":"Eur J Cardiothorac Surg"},{"issue":"5","key":"10.1016\/j.jscai.2022.100452_bib13","doi-asserted-by":"crossref","first-page":"e99","DOI":"10.1016\/j.athoracsur.2015.02.124","article-title":"Hybrid approach for off-pump pulmonary valve replacement in patients with a dilated right ventricular outflow tract","volume":"100","author":"Porras","year":"2015","journal-title":"Ann Thorac Surg"},{"issue":"2","key":"10.1016\/j.jscai.2022.100452_bib14","doi-asserted-by":"crossref","first-page":"e145","DOI":"10.1016\/j.jtcvs.2014.04.046","article-title":"A\u00a0novel hybrid technique for transcatheter pulmonary valve implantation within a dilated native right ventricular outflow tract","volume":"148","author":"Travelli","year":"2014","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"issue":"8","key":"10.1016\/j.jscai.2022.100452_bib15","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.118.006453","article-title":"Intentional fracture of bioprosthetic valve frames in patients undergoing valve-in-valve transcatheter pulmonary valve replacement","volume":"11","author":"Shahanavaz","year":"2018","journal-title":"Circ Cardiovasc Interv"},{"issue":"1","key":"10.1016\/j.jscai.2022.100452_bib16","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.121.010852","article-title":"Long-term outcomes after melody transcatheter pulmonary valve replacement in the US investigational device exemption trial","volume":"15","author":"Jones","year":"2022","journal-title":"Circ Cardiovasc Interv"},{"issue":"3","key":"10.1016\/j.jscai.2022.100452_bib17","first-page":"534","article-title":"Prestenting for prevention of melody valve stent fractures: a systematic review and meta-analysis","volume":"87","author":"Cardoso","year":"2016","journal-title":"Catheter Cardiovasc Interv"},{"issue":"7","key":"10.1016\/j.jscai.2022.100452_bib18","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.119.008963","article-title":"Munich comparative study: prospective long-term outcome of the transcatheter melody valve versus surgical pulmonary bioprosthesis with up to 12 years of follow-up","volume":"13","author":"Georgiev","year":"2020","journal-title":"Circ Cardiovasc Interv"},{"issue":"13","key":"10.1016\/j.jscai.2022.100452_bib19","article-title":"Infective endocarditis after melody valve implantation in the pulmonary position: a systematic review","volume":"7","author":"Abdelghani","year":"2018","journal-title":"J\u00a0Am Heart Assoc"},{"issue":"10","key":"10.1016\/j.jscai.2022.100452_bib20","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1136\/heartjnl-2014-306761","article-title":"Infective endocarditis of a transcatheter pulmonary valve in comparison with surgical implants","volume":"101","author":"van Dijck","year":"2015","journal-title":"Heart"},{"issue":"27","key":"10.1016\/j.jscai.2022.100452_bib21","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1093\/eurheartj\/ehz201","article-title":"Acute and midterm outcomes of the post-approval MELODY registry: a multicentre registry of transcatheter pulmonary valve implantation","volume":"40","author":"Nordmeyer","year":"2019","journal-title":"Eur Heart J"},{"issue":"4","key":"10.1016\/j.jscai.2022.100452_bib22","first-page":"625","article-title":"Risk factors for infective endocarditis following transcatheter pulmonary valve replacement in patients with congenital heart disease","volume":"94","author":"Sadeghi","year":"2019","journal-title":"Catheter Cardiovasc Interv"},{"issue":"16","key":"10.1016\/j.jscai.2022.100452_bib23","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1016\/j.jcin.2019.03.037","article-title":"A\u00a0low residual pressure gradient yields excellent long-term outcome after percutaneous pulmonary valve implantation","volume":"12","author":"Georgiev","year":"2019","journal-title":"JACC Cardiovasc Interv"},{"issue":"1","key":"10.1016\/j.jscai.2022.100452_bib24","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.jacc.2021.10.031","article-title":"Reintervention and survival after transcatheter pulmonary valve replacement","volume":"79","author":"McElhinney","year":"2022","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"6","key":"10.1016\/j.jscai.2022.100452_bib25","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.jacc.2021.05.044","article-title":"Multicenter study of endocarditis after transcatheter pulmonary valve replacement","volume":"78","author":"McElhinney","year":"2021","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"4","key":"10.1016\/j.jscai.2022.100452_bib26","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1007\/s00246-021-02801-z","article-title":"Selective valve removal for melody valve endocarditis: practice variations in a multicenter experience","volume":"43","author":"Davtyan","year":"2022","journal-title":"Pediatr Cardiol"},{"issue":"5","key":"10.1016\/j.jscai.2022.100452_bib27","first-page":"659","article-title":"Percutaneous replacement of pulmonary valve using the Edwards-Cribier percutaneous heart valve: first report in a human patient","volume":"67","author":"Garay","year":"2006","journal-title":"Catheter Cardiovasc Interv"},{"issue":"3","key":"10.1016\/j.jscai.2022.100452_bib28","first-page":"455","article-title":"Initial results from the off-label use of the Sapien S3 valve for percutaneous transcatheter pulmonary valve replacement: a multi-institutional experience","volume":"93","author":"Sinha","year":"2019","journal-title":"Catheter Cardiovasc Interv"},{"issue":"2","key":"10.1016\/j.jscai.2022.100452_bib29","first-page":"324","article-title":"SAPIEN valve for percutaneous transcatheter pulmonary valve replacement without \u201cpre-stenting\u201d: a multi-institutional experience","volume":"93","author":"Morgan","year":"2019","journal-title":"Catheter Cardiovasc Interv"},{"issue":"24","key":"10.1016\/j.jscai.2022.100452_bib32","doi-asserted-by":"crossref","first-page":"2847","DOI":"10.1016\/j.jacc.2020.10.041","article-title":"Transcatheter pulmonary valve replacement with the Sapien prosthesis","volume":"76","author":"Shahanavaz","year":"2020","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"6","key":"10.1016\/j.jscai.2022.100452_bib30","first-page":"1287","article-title":"Sapien S3 valve deployment in the pulmonary position using the gore DrySeal sheath to protect the tricuspid valve","volume":"96","author":"Stapleton","year":"2020","journal-title":"Catheter Cardiovasc Interv"},{"issue":"3","key":"10.1016\/j.jscai.2022.100452_bib31","first-page":"409","article-title":"Use of 65 cm large caliber Dryseal sheaths to facilitate delivery of the Edwards SAPIEN valve to dysfunctional right ventricular outflow tracts","volume":"94","author":"Kenny","year":"2019","journal-title":"Catheter Cardiovasc Interv"},{"issue":"19","key":"10.1016\/j.jscai.2022.100452_bib33","doi-asserted-by":"crossref","first-page":"1920","DOI":"10.1016\/j.jcin.2018.06.001","article-title":"3-year outcomes of the Edwards SAPIEN transcatheter heart valve for conduit failure in the pulmonary position from the COMPASSION multicenter clinical trial","volume":"11","author":"Kenny","year":"2018","journal-title":"JACC Cardiovasc Interv"},{"issue":"5","key":"10.1016\/j.jscai.2022.100452_bib34","first-page":"925","article-title":"Early leaflet thrombosis complicating transcatheter implantation of a Sapien 3 valve in a native right ventricular outflow tract","volume":"92","author":"Riahi","year":"2018","journal-title":"Catheter Cardiovasc Interv"},{"issue":"7","key":"10.1016\/j.jscai.2022.100452_bib35","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1007\/s00246-021-02652-8","article-title":"Aspirin use and transcatheter pulmonary valve replacement, the need for consistency","volume":"42","author":"Shibbani","year":"2021","journal-title":"Pediatr Cardiol"},{"issue":"10","key":"10.1016\/j.jscai.2022.100452_bib36","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1016\/j.jcmg.2021.04.023","article-title":"Hypoattenuated leaflet thickening after transcatheter pulmonary valve replacement with the SAPIEN 3 valve","volume":"14","author":"Hammadah","year":"2021","journal-title":"JACC Cardiovasc Imaging"},{"issue":"8","key":"10.1016\/j.jscai.2022.100452_bib37","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1016\/j.amjcard.2017.07.034","article-title":"Patient selection process for the harmony transcatheter pulmonary valve early feasibility study","volume":"120","author":"Gillespie","year":"2017","journal-title":"Am J Cardiol"},{"issue":"7","key":"10.1016\/j.jscai.2022.100452_bib38","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/j.jcin.2021.01.046","article-title":"5-year outcomes from the harmony native outflow tract early feasibility study","volume":"14","author":"Gillespie","year":"2021","journal-title":"JACC Cardiovasc Interv"},{"issue":"8","key":"10.1016\/j.jscai.2022.100452_bib39","first-page":"1903","article-title":"Midterm outcomes from the harmony transcatheter pulmonary valve pivotal trial and continued access study","volume":"42","author":"Gillespie","year":"2021","journal-title":"Pediatr Cardiol"},{"issue":"3","key":"10.1016\/j.jscai.2022.100452_bib40","first-page":"100326","article-title":"O-6 | One-year outcomes in an expanded cohort of harmony transcatheter pulmonary valve recipients","volume":"1","author":"Levi","year":"2022","journal-title":"J\u00a0Soc Cardiovasc Angiogr Interv"},{"issue":"5","key":"10.1016\/j.jscai.2022.100452_bib41","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1093\/eurheartj\/ehz610","article-title":"Critical isthmus of ventricular tachycardia covered by transcatheter pulmonary valve in a patient with tetralogy of Fallot","volume":"41","author":"Combes","year":"2020","journal-title":"Eur Heart J"},{"issue":"6","key":"10.1016\/j.jscai.2022.100452_bib42","first-page":"1125","article-title":"First human implant of the Alterra Adaptive Prestent TM: a new self-expanding device designed to remodel the right ventricular outflow tract","volume":"91","author":"Zahn","year":"2018","journal-title":"Catheter Cardiovasc Interv"},{"issue":"21","key":"10.1016\/j.jscai.2022.100452_bib43","doi-asserted-by":"crossref","first-page":"2510","DOI":"10.1016\/j.jcin.2020.06.039","article-title":"Alterra adaptive Prestent and SAPIEN 3 THV for congenital pulmonic valve dysfunction: an early feasibility study","volume":"13","author":"Shahanavaz","year":"2020","journal-title":"JACC Cardiovasc Interv"},{"issue":"8","key":"10.1016\/j.jscai.2022.100452_bib44","first-page":"1910","article-title":"Transcatheter pulmonary valve implantation with the Alterra adaptive Prestent and SAPIEN 3 transcatheter heart valve: one-year outcomes of the ALTERRA pivotal trial","volume":"42","author":"Zahn","year":"2021","journal-title":"Pediatr Cardiol"},{"issue":"19","key":"10.1016\/j.jscai.2022.100452_bib45","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1016\/j.jcin.2019.07.036","article-title":"First-in-man implantation of Med-zenith PT-Valve in right ventricular outflow tract for pulmonary regurgitation","volume":"12","author":"Shang","year":"2019","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jscai.2022.100452_bib46","doi-asserted-by":"crossref","first-page":"887886","DOI":"10.3389\/fcvm.2022.887886","article-title":"The clinical trial outcomes of Med-zenith PT-Valve in the treatment of patients with severe pulmonary regurgitation","volume":"9","author":"Shang","year":"2022","journal-title":"Front Cardiovasc Med"},{"issue":"6","key":"10.1016\/j.jscai.2022.100452_bib47","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.118.006494","article-title":"Successful feasibility human trial of a new self-expandable percutaneous pulmonary valve (Pulsta valve) implantation using knitted nitinol wire backbone and trileaflet \u03b1-Gal-free porcine pericardial valve in the native right ventricular outflow tract","volume":"11","author":"Kim","year":"2018","journal-title":"Circ Cardiovasc Interv"},{"issue":"5","key":"10.1016\/j.jscai.2022.100452_bib48","first-page":"E724","article-title":"Mid-term outcomes of the Pulsta transcatheter pulmonary valve for the native right ventricular outflow tract","volume":"98","author":"Lee","year":"2021","journal-title":"Catheter Cardiovasc Interv"},{"issue":"5","key":"10.1016\/j.jscai.2022.100452_bib49","first-page":"923","article-title":"Bilateral branch pulmonary artery Pulsta valve implantation for treatment of large right ventricular outflow tract in a high-risk patient","volume":"98","author":"Kim","year":"2021","journal-title":"Catheter Cardiovasc Interv"},{"issue":"2","key":"10.1016\/j.jscai.2022.100452_bib50","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1007\/s12471-016-0932-5","article-title":"Early experience with the Venus p-valve for percutaneous pulmonary valve implantation in native outflow tract","volume":"25","author":"Garay","year":"2017","journal-title":"Neth Heart J"},{"issue":"7","key":"10.1016\/j.jscai.2022.100452_bib51","first-page":"1131","article-title":"Early clinical experience with a novel self-expanding percutaneous stent-valve in the native right ventricular outflow tract","volume":"84","author":"Cao","year":"2014","journal-title":"Catheter Cardiovasc Interv"},{"issue":"13","key":"10.1016\/j.jscai.2022.100452_bib52","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.4244\/EIJ-D-18-00299","article-title":"Medium-term results of percutaneous pulmonary valve implantation using the Venus P-valve: international experience","volume":"14","author":"Morgan","year":"2019","journal-title":"EuroIntervention"},{"issue":"4","key":"10.1016\/j.jscai.2022.100452_bib53","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1017\/S1047951115001067","article-title":"Percutaneous pulmonary valve implantation with the Venus P-valve: clinical experience and early results","volume":"26","author":"Promphan","year":"2016","journal-title":"Cardiol Young"}],"container-title":["Journal of the Society for Cardiovascular Angiography &amp; Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772930322004501?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772930322004501?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T00:30:47Z","timestamp":1762648247000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2772930322004501"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":53,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["S2772930322004501"],"URL":"https:\/\/doi.org\/10.1016\/j.jscai.2022.100452","relation":{},"ISSN":["2772-9303"],"issn-type":[{"value":"2772-9303","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transcatheter Pulmonary Valve Replacement: A Review of Current Valve Technologies","name":"articletitle","label":"Article Title"},{"value":"Journal of the Society for Cardiovascular Angiography & Interventions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jscai.2022.100452","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Author(s). Published by Elsevier Inc. on behalf of the Society for Cardiovascular Angiography and Interventions Foundation.","name":"copyright","label":"Copyright"}],"article-number":"100452"}}