{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T14:27:11Z","timestamp":1792160831289,"version":"4.4.0"},"reference-count":22,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jshoulderelbow.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Shoulder and Elbow Surgery"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.jse.2025.07.022","type":"journal-article","created":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T15:35:43Z","timestamp":1756740943000},"page":"689-696","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Preoperative testosterone replacement therapy is associated with increased rates of periprosthetic joint infection, acute kidney injury, and emergency department utilization after total shoulder arthroplasty: a propensity-score matched analysis"],"prefix":"10.1016","volume":"35","author":[{"given":"Alexander E.","family":"White","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9718-3803","authenticated-orcid":false,"given":"Argen","family":"Omurzakov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arsen M.","family":"Omurzakov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian E.","family":"Athanasian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8959-8376","authenticated-orcid":false,"given":"Christopher M.","family":"Brusalis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle E.","family":"Kew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael C.","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence V.","family":"Gulotta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel A.","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jse.2025.07.022_bib1","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1046\/j.1532-5415.2002.50462.x","article-title":"Preoperative supraphysiological testosterone in older men undergoing knee replacement surgery","volume":"50","author":"Amory","year":"2002","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.jse.2025.07.022_bib2","doi-asserted-by":"crossref","first-page":"123","DOI":"10.3390\/pathophysiology30020011","article-title":"Hormone replacement therapy does not eliminate risk factors for joint complications following total joint arthroplasty: a matched cohort study","volume":"30","author":"Collins","year":"2023","journal-title":"Pathophysiology"},{"key":"10.1016\/j.jse.2025.07.022_bib3","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/dom.14206","article-title":"Mechanisms underlying the metabolic actions of testosterone in humans: a narrative review","volume":"23","author":"Dandona","year":"2021","journal-title":"Diabetes Obes Metab"},{"key":"10.1016\/j.jse.2025.07.022_bib4","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1093\/jsxmed\/qdae138","article-title":"Association of testosterone replacement therapy with atrial fibrillation and acute kidney injury","volume":"21","author":"Greenberg","year":"2024","journal-title":"J Sex Med"},{"key":"10.1016\/j.jse.2025.07.022_bib5","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.thromres.2018.10.023","article-title":"Testosterone therapy and venous thromboembolism: a systematic review and meta-analysis","volume":"172","author":"Houghton","year":"2018","journal-title":"Thromb Res"},{"key":"10.1016\/j.jse.2025.07.022_bib6","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1056\/NEJMoa2215025","article-title":"Cardiovascular safety of testosterone-replacement therapy","volume":"389","author":"Lincoff","year":"2023","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jse.2025.07.022_bib7","doi-asserted-by":"crossref","first-page":"921","DOI":"10.21037\/tau.2016.09.08","article-title":"Impact of recent FDA ruling on testosterone replacement therapy (TRT)","volume":"5","author":"Metzger","year":"2016","journal-title":"Transl Androl Urol"},{"key":"10.1016\/j.jse.2025.07.022_bib8","doi-asserted-by":"crossref","first-page":"207","DOI":"10.4266\/acc.2024.00591","article-title":"Sex or gender differences in treatment outcomes of sepsis and septic shock","volume":"39","author":"Min","year":"2024","journal-title":"ACC"},{"key":"10.1016\/j.jse.2025.07.022_bib9","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1038\/s42003-024-06470-5","article-title":"The effect of testosterone on the gut microbiome in mice","volume":"7","author":"Moadi","year":"2024","journal-title":"Commun Biol"},{"key":"10.1016\/j.jse.2025.07.022_bib10","doi-asserted-by":"crossref","first-page":"427","DOI":"10.2147\/TCRM.S3025","article-title":"The benefits and risks of testosterone replacement therapy: a review","volume":"5","author":"Morley","year":"2009","journal-title":"TCRM"},{"key":"10.1016\/j.jse.2025.07.022_bib11","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.3390\/jcm14041341","article-title":"Testosterone replacement therapy is not associated with greater revision rates in reverse total shoulder arthroplasty","volume":"14","author":"Parmar","year":"2025","journal-title":"J Clin Med"},{"key":"10.1016\/j.jse.2025.07.022_bib12","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.2106\/JBJS.K.00861","article-title":"Prognostic factors for bacterial cultures positive for Propionibacterium acnes and other organisms in a large series of revision shoulder arthroplasties performed for stiffness, pain, or loosening","volume":"94","author":"Pottinger","year":"2012","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.jse.2025.07.022_bib14","doi-asserted-by":"crossref","DOI":"10.2106\/JBJS.OA.21.00030","article-title":"Association between serum testosterone levels and cutibacterium skin load in patients undergoing elective shoulder arthroplasty: a cohort study","volume":"6","author":"Schiffman","year":"2021","journal-title":"JBJS Open Access"},{"key":"10.1016\/j.jse.2025.07.022_bib15","doi-asserted-by":"crossref","first-page":"581","DOI":"10.5435\/JAAOS-D-22-00554","article-title":"The relationship between testosterone therapy and rotator cuff tears, repairs, and revision repairs","volume":"31","author":"Testa","year":"2023","journal-title":"J Am Acad Orthop Surg"},{"key":"10.1016\/j.jse.2025.07.022_bib16","article-title":"Cutibacterium acnes and its complex host interaction in prosthetic joint infection: current insights and future directions","volume":"17","author":"Thoraval","year":"2024","journal-title":"Res Microbiol"},{"key":"10.1016\/j.jse.2025.07.022_bib17","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1530\/EJE-08-0702","article-title":"Measures of bioavailable serum testosterone and estradiol and their relationships with muscle mass, muscle strength and bone mineral density in postmenopausal women: a cross-sectional study","volume":"160","author":"Van Geel","year":"2009","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.jse.2025.07.022_bib18","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1097\/EDE.0b013e3181577511","article-title":"Strengthening the reporting of observational studies in epidemiology (STROBE): explanation and elaboration","volume":"18","author":"Vandenbroucke","year":"2007","journal-title":"Epidemiology"},{"key":"10.1016\/j.jse.2025.07.022_bib19","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.2165\/11536910-000000000-00000","article-title":"Testosterone physiology in resistance exercise and training: the Up-Stream regulatory elements","volume":"40","author":"Vingren","year":"2010","journal-title":"Sports Med"},{"key":"10.1016\/j.jse.2025.07.022_bib20","doi-asserted-by":"crossref","first-page":"2601","DOI":"10.1016\/j.jse.2020.03.049","article-title":"The incidence of shoulder arthroplasty: rise and future projections compared with hip and knee arthroplasty","volume":"29","author":"Wagner","year":"2020","journal-title":"J Shoulder Elbow Surg"},{"key":"10.1016\/j.jse.2025.07.022_bib21","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1001\/jamainternmed.2019.5135","article-title":"Association of testosterone therapy with risk of venous thromboembolism among men with and without hypogonadism","volume":"180","author":"Walker","year":"2020","journal-title":"JAMA Intern Med"},{"key":"10.1016\/j.jse.2025.07.022_bib22","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1186\/1741-7015-11-108","article-title":"Testosterone therapy and cardiovascular events among men: a systematic review and meta-analysis of placebo-controlled randomized trials","volume":"11","author":"Xu","year":"2013","journal-title":"BMC Med"},{"key":"10.1016\/j.jse.2025.07.022_bib23","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1007\/s40266-019-00716-2","article-title":"Is testosterone replacement therapy in older men effective and safe?","volume":"36","author":"Yabluchanskiy","year":"2019","journal-title":"Drugs Aging"}],"container-title":["Journal of Shoulder and Elbow Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1058274625006226?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1058274625006226?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T21:21:13Z","timestamp":1770412873000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1058274625006226"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["S1058274625006226"],"URL":"https:\/\/doi.org\/10.1016\/j.jse.2025.07.022","relation":{},"ISSN":["1058-2746"],"issn-type":[{"value":"1058-2746","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Preoperative testosterone replacement therapy is associated with increased rates of periprosthetic joint infection, acute kidney injury, and emergency department utilization after total shoulder arthroplasty: a propensity-score matched analysis","name":"articletitle","label":"Article Title"},{"value":"Journal of Shoulder and Elbow Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jse.2025.07.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Journal of Shoulder and Elbow Surgery Board of Trustees.","name":"copyright","label":"Copyright"}]}}