{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T00:59:24Z","timestamp":1792976364562,"version":"4.5.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jshoulderelbow.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Shoulder and Elbow Surgery"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.jse.2026.05.006","type":"journal-article","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T16:16:47Z","timestamp":1779380207000},"page":"2746-2755","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Statin therapy is not associated with inferior postoperative outcomes after arthroscopic rotator cuff repair: a systematic review and meta-analysis"],"prefix":"10.1016","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-0181-6939","authenticated-orcid":false,"given":"Areeb","family":"Ahmad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maazen","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7508-9818","authenticated-orcid":false,"given":"Kassem","family":"Ghayyad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olamide","family":"Oshikoya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5457-4910","authenticated-orcid":false,"given":"Daniel","family":"Goltz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2277-5080","authenticated-orcid":false,"given":"G. Russell","family":"Huffman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jse.2026.05.006_bib1","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1016\/j.jse.2021.05.014","article-title":"Does statin-treated hyperlipidemia affect rotator cuff healing or muscle fatty infiltration after rotator cuff repair?","volume":"30","author":"Amit","year":"2021","journal-title":"J Shoulder Elbow Surg"},{"key":"10.1016\/j.jse.2026.05.006_bib2","first-page":"457","article-title":"Statins: bitter enemies of tendons or not? A systematic review of clinical evidence","volume":"29","author":"Anzillotti","year":"2025","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"10.1016\/j.jse.2026.05.006_bib3","doi-asserted-by":"crossref","first-page":"2948","DOI":"10.1177\/0363546517717686","article-title":"Perioperative serum lipid status and statin use affect the revision surgery rate after Arthroscopic Rotator Cuff Repair","volume":"45","author":"Cancienne","year":"2017","journal-title":"Am J Sports Med"},{"key":"10.1016\/j.jse.2026.05.006_bib4","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/j.jse.2018.10.013","article-title":"Establishing clinically significant outcome after arthroscopic rotator cuff repair","volume":"28","author":"Cvetanovich","year":"2019","journal-title":"J Shoulder Elbow Surg"},{"key":"10.1016\/j.jse.2026.05.006_bib5","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1519\/JSC.0000000000002946","article-title":"Effect sizes for paired data should use the change Score variability rather than the pre-test variability","volume":"35","author":"Dankel","year":"2021","journal-title":"J Strength Cond Res"},{"key":"10.1016\/j.jse.2026.05.006_bib6","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.jse.2014.06.048","article-title":"Simvastatin reduces fibrosis and protects against muscle weakness after massive rotator cuff tear","volume":"24","author":"Davis","year":"2015","journal-title":"J Shoulder Elbow Surg"},{"key":"10.1016\/j.jse.2026.05.006_bib7","doi-asserted-by":"crossref","first-page":"2107","DOI":"10.1016\/j.jse.2024.12.031","article-title":"Predicting rotator cuff retear after arthroscopic repair: a lipoprotein-based model","volume":"34","author":"Ding","year":"2025","journal-title":"J Shoulder Elbow Surg"},{"key":"10.1016\/j.jse.2026.05.006_bib8","doi-asserted-by":"crossref","first-page":"2869","DOI":"10.1177\/0363546514545856","article-title":"Statins enhance rotator cuff healing by stimulating the COX2\/PGE2\/EP4 pathway: an in vivo and in vitro study","volume":"42","author":"Dolkart","year":"2014","journal-title":"Am J Sports Med"},{"key":"10.1016\/j.jse.2026.05.006_bib9","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-53238-7","article-title":"Statin treatment increases the clinical risk of tendinopathy through matrix metalloproteinase release - a cohort study design combined with an experimental study","volume":"9","author":"Eliasson","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.jse.2026.05.006_bib10","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0172797","article-title":"Simvastatin and atorvastatin reduce the mechanical properties of tendon constructs in vitro and introduce catabolic changes in the gene expression pattern","volume":"12","author":"Eliasson","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.jse.2026.05.006_bib11","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1177\/0363546520914632","article-title":"Predictive modeling to determine functional outcomes after Arthroscopic Rotator Cuff Repair","volume":"48","author":"Frangiamore","year":"2020","journal-title":"Am J Sports Med"},{"key":"10.1016\/j.jse.2026.05.006_bib12","doi-asserted-by":"crossref","first-page":"2086","DOI":"10.1016\/j.jse.2017.05.009","article-title":"Hyperlipidemia increases the risk of retear after arthroscopic rotator cuff repair","volume":"26","author":"Garcia","year":"2017","journal-title":"J Shoulder Elbow Surg"},{"key":"10.1016\/j.jse.2026.05.006_bib13","doi-asserted-by":"crossref","first-page":"1988","DOI":"10.1177\/03635465231175476","article-title":"Relationship of missed statin therapy and 10-Year atherosclerotic cardiovascular disease risk Score to retear rate after Arthroscopic Rotator Cuff Repair","volume":"51","author":"Lee","year":"2023","journal-title":"Am J Sports Med"},{"key":"10.1016\/j.jse.2026.05.006_bib14","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000100","article-title":"The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration","volume":"6","author":"Liberati","year":"2009","journal-title":"PLoS Med"},{"key":"10.1016\/j.jse.2026.05.006_bib15","doi-asserted-by":"crossref","first-page":"778","DOI":"10.2106\/JBJS.M.00583","article-title":"Factors affecting rotator cuff healing","volume":"96","author":"Mall","year":"2014","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.jse.2026.05.006_bib16","doi-asserted-by":"crossref","first-page":"3447","DOI":"10.1177\/0363546520962512","article-title":"Time required to achieve clinically significant outcomes after Arthroscopic Rotator Cuff Repair","volume":"48","author":"Manderle","year":"2020","journal-title":"Am J Sports Med"},{"key":"10.1016\/j.jse.2026.05.006_bib17","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1177\/0363546514529644","article-title":"Rotator cuff repair: published evidence on factors associated with repair integrity and clinical outcome","volume":"43","author":"McElvany","year":"2015","journal-title":"Am J Sports Med"},{"key":"10.1016\/j.jse.2026.05.006_bib18","doi-asserted-by":"crossref","DOI":"10.1177\/23259671241305089","article-title":"Association of antihypertensive and Statin medication usage with postoperative stiffness after Arthroscopic Rotator Cuff Repair: a retrospective cohort Study","volume":"13","author":"Perez","year":"2025","journal-title":"Orthop J Sports Med"},{"key":"10.1016\/j.jse.2026.05.006_bib19","doi-asserted-by":"crossref","first-page":"1824","DOI":"10.1016\/j.jse.2018.06.019","article-title":"A prospective evaluation of predictors of pain after arthroscopic rotator cuff repair: psychosocial factors have a stronger association than structural factors","volume":"27","author":"Ravindra","year":"2018","journal-title":"J Shoulder Elbow Surg"},{"key":"10.1016\/j.jse.2026.05.006_bib20","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1007\/s10654-010-9491-z","article-title":"Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses","volume":"25","author":"Stang","year":"2010","journal-title":"Eur J Epidemiol"},{"key":"10.1016\/j.jse.2026.05.006_bib21","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1016\/j.jse.2019.11.018","article-title":"Minimal clinically important differences in the American Shoulder and Elbow Surgeons, Simple Shoulder Test, and visual analog scale pain scores after arthroscopic rotator cuff repair","volume":"29","author":"Tashjian","year":"2020","journal-title":"J Shoulder Elbow Surg"},{"key":"10.1016\/j.jse.2026.05.006_bib22","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1186\/1471-2288-14-135","article-title":"Estimating the sample mean and standard deviation from the sample size, median, range and\/or interquartile range","volume":"14","author":"Wan","year":"2014","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.jse.2026.05.006_bib23","doi-asserted-by":"crossref","first-page":"2179","DOI":"10.1016\/j.arthro.2024.11.066","article-title":"Statin use not linked to Rotator Cuff Retear after Arthroscopic Rotator Cuff Repair","volume":"41","author":"Yamakado","year":"2025","journal-title":"Arthroscopy"},{"key":"10.1016\/j.jse.2026.05.006_bib24","doi-asserted-by":"crossref","first-page":"873","DOI":"10.4055\/cios23131","article-title":"Current research on the influence of Statin treatment on Rotator Cuff healing","volume":"15","author":"Yoon","year":"2023","journal-title":"Clin Orthop Surg"},{"key":"10.1016\/j.jse.2026.05.006_bib25","doi-asserted-by":"crossref","first-page":"2518","DOI":"10.1177\/0363546520937266","article-title":"Dyslipidemia with perioperative Statin usage is not associated with poorer 24-Month functional outcomes after Arthroscopic Rotator Cuff surgery","volume":"48","author":"Zeng","year":"2020","journal-title":"Am J Sports Med"}],"container-title":["Journal of Shoulder and Elbow Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1058274626003009?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1058274626003009?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T23:25:12Z","timestamp":1791588312000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1058274626003009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":25,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["S1058274626003009"],"URL":"https:\/\/doi.org\/10.1016\/j.jse.2026.05.006","relation":{},"ISSN":["1058-2746"],"issn-type":[{"value":"1058-2746","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Statin therapy is not associated with inferior postoperative outcomes after arthroscopic rotator cuff repair: a systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Journal of Shoulder and Elbow Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jse.2026.05.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc. on behalf of Journal of Shoulder and Elbow Surgery Board of Trustees.","name":"copyright","label":"Copyright"}]}}