{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T13:07:40Z","timestamp":1778850460610,"version":"3.51.4"},"reference-count":66,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:00:00Z","timestamp":1760140800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1194141"],"award-info":[{"award-number":["APP1194141"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1042465"],"award-info":[{"award-number":["APP1042465"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1041760"],"award-info":[{"award-number":["APP1041760"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1156511"],"award-info":[{"award-number":["APP1156511"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Sport and Health Science"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.jshs.2025.101095","type":"journal-article","created":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T16:38:17Z","timestamp":1760546297000},"page":"101095","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Influence of diet-induced obesity and voluntary exercise training on cardiac lipids and mitochondrial function in mice"],"prefix":"10.1016","volume":"15","author":[{"given":"Nimna","family":"Perera","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minh","family":"Deo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Surafel","family":"Tegegne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yow Keat","family":"Tham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalie A.","family":"Mellett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anida","family":"Velagic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex M.","family":"Parker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver K.","family":"Fuller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren V.","family":"Terry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Casey L.","family":"Egan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter J.","family":"Meikle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca H.","family":"Ritchie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark A.","family":"Febbraio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miles J.","family":"De Blasio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jshs.2025.101095_bib0001","article-title":"Psychological impact of obesity: A comprehensive analysis of health-related quality of life and weight-related symptoms","volume":"45","author":"Jaison","year":"2024","journal-title":"Obes Med"},{"key":"10.1016\/j.jshs.2025.101095_bib0002","doi-asserted-by":"crossref","first-page":"e984","DOI":"10.1161\/CIR.0000000000000973","article-title":"Obesity and cardiovascular disease: A scientific statement from the American Heart Association","volume":"143","author":"Powell-Wiley","year":"2021","journal-title":"Circulation"},{"key":"10.1016\/j.jshs.2025.101095_bib0003","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1016\/j.jacc.2022.11.005","article-title":"The global burden of cardiovascular diseases and risk: A compass for further health","volume":"80","author":"Vaduganathan","year":"2022","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jshs.2025.101095_bib0004","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1152\/physrev.00030.2020","article-title":"Obesity cardiomyopathy: Evidence, mechanisms, and therapeutic implications","volume":"101","author":"Ren","year":"2021","journal-title":"Physiol Rev"},{"key":"10.1016\/j.jshs.2025.101095_bib0005","doi-asserted-by":"crossref","first-page":"61","DOI":"10.3164\/jcbn.22-73","article-title":"High-fat diet causes mitochondrial damage and downregulation of mitofusin-2 and optic atrophy-1 in multiple organs","volume":"73","author":"Zheng","year":"2023","journal-title":"J Clin Biochem Nutr"},{"key":"10.1016\/j.jshs.2025.101095_bib0006","doi-asserted-by":"crossref","unstructured":"Chen D, Li X, Zhang LT, Zhu M, Gao L. A high-fat diet impairs mitochondrial biogenesis, mitochondrial dynamics, and the respiratory chain complex in rat myocardial tissues. J Cell Biochem;119:9602. doi: 10.1002\/jcb.27068.","DOI":"10.1002\/jcb.27068"},{"key":"10.1016\/j.jshs.2025.101095_bib0007","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1161\/CIRCRESAHA.119.315252","article-title":"Increased Drp1 acetylation by lipid overload induces cardiomyocyte death and heart dysfunction","volume":"126","author":"Hu","year":"2020","journal-title":"Circ Res"},{"key":"10.1016\/j.jshs.2025.101095_bib0008","doi-asserted-by":"crossref","first-page":"e2","DOI":"10.1161\/01.CIR.0000048890.59383.8D","article-title":"Cardiology patient pages. Exercise and cardiovascular health","volume":"107","author":"Myers","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.jshs.2025.101095_bib0009","first-page":"97","article-title":"The athlete\u2019s heart vs. the failing heart: Can signaling explain the two distinct outcomes?","volume":"26","author":"Weeks","year":"2011","journal-title":"Physiology (Bethesda)"},{"key":"10.1016\/j.jshs.2025.101095_bib0010","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.cmet.2007.09.001","article-title":"A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy","volume":"6","author":"O\u2019Neill","year":"2007","journal-title":"Cell Metab"},{"key":"10.1016\/j.jshs.2025.101095_bib0011","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.2337\/db07-0481","article-title":"Mitochondrial energetics in the heart in obesity-related diabetes: Direct evidence for increased uncoupled respiration and activation of uncoupling proteins","volume":"56","author":"Boudina","year":"2007","journal-title":"Diabetes"},{"key":"10.1016\/j.jshs.2025.101095_bib0012","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1093\/cvr\/cvu065","article-title":"Sex differences in exercise-induced physiological myocardial hypertrophy are modulated by oestrogen receptor beta","volume":"102","author":"Dworatzek","year":"2014","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.jshs.2025.101095_bib0013","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s00424-017-2076-x","article-title":"Resistance exercise improves cardiac function and mitochondrial efficiency in diabetic rat hearts","volume":"470","author":"Ko","year":"2018","journal-title":"Pflugers Archi"},{"key":"10.1016\/j.jshs.2025.101095_bib0014","doi-asserted-by":"crossref","first-page":"3450","DOI":"10.1128\/MCB.00426-14","article-title":"Insulin receptor substrates are essential for the bioenergetic and hypertrophic response of the heart to exercise training","volume":"34","author":"Riehle","year":"2014","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.jshs.2025.101095_bib0015","doi-asserted-by":"crossref","first-page":"H246","DOI":"10.1152\/ajpheart.00734.2006","article-title":"Restoration of CREB function is linked to completion and stabilization of adaptive cardiac hypertrophy in response to exercise","volume":"293","author":"Watson","year":"2007","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.jshs.2025.101095_bib0016","doi-asserted-by":"crossref","first-page":"222","DOI":"10.3390\/biom11020222","article-title":"The role of cardiolipin as a scaffold mitochondrial phospholipid in autophagosome formation: In vitro evidence","volume":"11","author":"Manganelli","year":"2021","journal-title":"Biomolecules"},{"key":"10.1016\/j.jshs.2025.101095_bib0017","doi-asserted-by":"crossref","first-page":"90","DOI":"10.3389\/fcell.2017.00090","article-title":"Role of cardiolipin in mitochondrial signaling pathways","volume":"5","author":"Dudek","year":"2017","journal-title":"Front Cell Dev Biol"},{"key":"10.1016\/j.jshs.2025.101095_bib0018","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.bbalip.2016.08.001","article-title":"Known unknowns of cardiolipin signaling: The best is yet to come","volume":"1862","author":"Maguire","year":"2017","journal-title":"Biochim Biophys Acta Mol Cell Biol Lipids"},{"key":"10.1016\/j.jshs.2025.101095_bib0019","first-page":"1638","article-title":"Cardiolipin alterations during obesity: Exploring therapeutic opportunities","volume":"11","author":"Prola","year":"2022","journal-title":"Biology (Basel)"},{"key":"10.1016\/j.jshs.2025.101095_bib0020","doi-asserted-by":"crossref","first-page":"134","DOI":"10.4330\/wjc.v9.i2.134","article-title":"Aerobic vs. anaerobic exercise training effects on the cardiovascular system","volume":"9","author":"Patel","year":"2017","journal-title":"World J Cardiol"},{"key":"10.1016\/j.jshs.2025.101095_bib0021","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/s10863-006-9052-z","article-title":"Cytochrome c oxidase subunit IV is essential for assembly and respiratory function of the enzyme complex","volume":"38","author":"Li","year":"2006","journal-title":"J Bioenerg Biomembr"},{"key":"10.1016\/j.jshs.2025.101095_bib0022","doi-asserted-by":"crossref","first-page":"C1129","DOI":"10.1152\/ajpcell.00233.2006","article-title":"Assembly of mitochondrial cytochrome c-oxidase, a complicated and highly regulated cellular process","volume":"291","author":"Fontanesi","year":"2006","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1016\/j.jshs.2025.101095_bib0023","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.cmet.2010.07.003","article-title":"Cardiolipin remodeling by ALCAT1 links oxidative stress and mitochondrial dysfunction to obesity","volume":"12","author":"Li","year":"2010","journal-title":"Cell Metab"},{"key":"10.1016\/j.jshs.2025.101095_bib0024","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1194\/jlr.M017939","article-title":"Perilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondria","volume":"52","author":"Wang","year":"2011","journal-title":"J Lipid Res"},{"key":"10.1016\/j.jshs.2025.101095_bib0025","doi-asserted-by":"crossref","first-page":"12355","DOI":"10.1073\/pnas.1934654100","article-title":"Phosphoinositide 3-kinase(p110\u03b1) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy","volume":"100","author":"McMullen","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jshs.2025.101095_bib0026","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2021.774681","article-title":"Cardiac effects of treadmill running at different intensities in a rat model","volume":"12","author":"Yan","year":"2021","journal-title":"Front Physiol"},{"key":"10.1016\/j.jshs.2025.101095_bib0027","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1016\/j.cmet.2017.04.025","article-title":"Molecular mechanisms underlying cardiac adaptation to exercise","volume":"25","author":"Vega","year":"2017","journal-title":"Cell Metab"},{"key":"10.1016\/j.jshs.2025.101095_bib0028","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/s12576-021-00818-w","article-title":"Cardioprotective responses to aerobic exercise-induced physiological hypertrophy in zebrafish heart","volume":"71","author":"Chen","year":"2021","journal-title":"J Physiolog Sci"},{"key":"10.1016\/j.jshs.2025.101095_bib0029","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1016\/j.cell.2010.11.036","article-title":"C\/EBP\u03b2 controls exercise-induced cardiac growth and protects against pathological cardiac remodeling","volume":"143","author":"Bostr\u00f6m","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.jshs.2025.101095_bib0030","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1194\/jlr.M600551-JLR200","article-title":"Loss of cardiac tetralinoleoyl cardiolipin in human and experimental heart failure","volume":"48","author":"Sparagna","year":"2007","journal-title":"J Lipid Res"},{"key":"10.1016\/j.jshs.2025.101095_bib0031","doi-asserted-by":"crossref","first-page":"557","DOI":"10.3803\/EnM.2015.30.4.557","article-title":"Diastolic dysfunction induced by a high-fat diet is associated with mitochondrial abnormality and adenosine triphosphate levels in rats","volume":"30","author":"Kang","year":"2015","journal-title":"Endocrinol Metab (Seoul)"},{"key":"10.1016\/j.jshs.2025.101095_bib0032","doi-asserted-by":"crossref","first-page":"728","DOI":"10.3390\/cells8070728","article-title":"Role of cardiolipin in mitochondrial function and dynamics in health and disease: Molecular and pharmacological aspects","volume":"8","author":"Paradies","year":"2019","journal-title":"Cells"},{"key":"10.1016\/j.jshs.2025.101095_bib0033","doi-asserted-by":"crossref","first-page":"C33","DOI":"10.1152\/ajpcell.00243.2006","article-title":"Role of cardiolipin alterations in mitochondrial dysfunction and disease","volume":"292","author":"Chicco","year":"2007","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1016\/j.jshs.2025.101095_bib0034","doi-asserted-by":"crossref","first-page":"eabd6322","DOI":"10.1126\/sciadv.abd6322","article-title":"Cardiolipin content controls mitochondrial coupling and energetic efficiency in muscle","volume":"7","author":"Prola","year":"2021","journal-title":"Sci Adv"},{"key":"10.1016\/j.jshs.2025.101095_bib0035","doi-asserted-by":"crossref","first-page":"16684","DOI":"10.1021\/bi051908a","article-title":"Shotgun lipidomics identifies cardiolipin depletion in diabetic myocardium linking altered substrate utilization with mitochondrial dysfunction","volume":"44","author":"Han","year":"2005","journal-title":"Biochemistry"},{"key":"10.1016\/j.jshs.2025.101095_bib0036","doi-asserted-by":"crossref","first-page":"6417","DOI":"10.1021\/bi7004015","article-title":"Alterations in myocardial cardiolipin content and composition occur at the very earliest stages of diabetes: A shotgun lipidomics study","volume":"46","author":"Han","year":"2007","journal-title":"Biochemistry"},{"key":"10.1016\/j.jshs.2025.101095_bib0037","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.jnutbio.2017.04.004","article-title":"Murine diet-induced obesity remodels cardiac and liver mitochondrial phospholipid acyl chains with differential effects on respiratory enzyme activity","volume":"45","author":"Sullivan","year":"2017","journal-title":"J Nutr Biochem"},{"key":"10.1016\/j.jshs.2025.101095_bib0038","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1097\/FJC.0b013e31819b5461","article-title":"Cardiolipin remodeling in the heart","volume":"53","author":"Sparagna","year":"2009","journal-title":"J Cardiovascu Pharmacol"},{"key":"10.1016\/j.jshs.2025.101095_bib0039","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1161\/01.RES.0000109416.56608.64","article-title":"Decrease in mitochondrial complex I activity in ischemic\/reperfused rat heart","volume":"94","author":"Paradies","year":"2004","journal-title":"Circ Res"},{"key":"10.1016\/j.jshs.2025.101095_bib0040","doi-asserted-by":"crossref","first-page":"H210","DOI":"10.1152\/ajpheart.00098.2010","article-title":"Tafazzin knockdown causes hypertrophy of neonatal ventricular myocytes","volume":"299","author":"He","year":"2010","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.jshs.2025.101095_bib0041","first-page":"H1","article-title":"Altered phospholipid metabolism in pressure-overload hypertrophied hearts","volume":"250","author":"Reibel","year":"1986","journal-title":"Am J Physiol"},{"key":"10.1016\/j.jshs.2025.101095_bib0042","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1007\/s00125-021-05430-6","article-title":"Exercise training improves mitochondrial respiration and is associated with an altered intramuscular phospholipid signature in women with obesity","volume":"64","author":"Mendham","year":"2021","journal-title":"Diabetologia"},{"key":"10.1016\/j.jshs.2025.101095_bib0043","doi-asserted-by":"crossref","first-page":"2142","DOI":"10.2337\/db07-0141","article-title":"Effects of physical activity and weight loss on skeletal muscle mitochondria and relationship with glucose control in type 2 diabetes","volume":"56","author":"Toledo","year":"2007","journal-title":"Diabetes"},{"key":"10.1016\/j.jshs.2025.101095_bib0044","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1093\/gerona\/61.6.534","article-title":"Effects of exercise on mitochondrial content and function in aging human skeletal muscle","volume":"61","author":"Menshikova","year":"2006","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.jshs.2025.101095_bib0045","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1161\/CIRCULATIONAHA.113.008476","article-title":"Myocardial contractile dysfunction is associated with impaired mitochondrial function and dynamics in type 2 diabetic but not in obese patients","volume":"130","author":"Montaigne","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.jshs.2025.101095_bib0046","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1093\/cvr\/cvv183","article-title":"Mitochondrial complex I defect and increased fatty acid oxidation enhance protein lysine acetylation in the diabetic heart","volume":"107","author":"Vazquez","year":"2015","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.jshs.2025.101095_bib0047","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.semcdb.2017.07.039","article-title":"Mitochondrial dynamics: The dynamin superfamily and execution by collusion","volume":"76","author":"Ramachandran","year":"2018","journal-title":"Semin Cell Dev Biol"},{"key":"10.1016\/j.jshs.2025.101095_bib0048","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1038\/s41419-021-03502-4","article-title":"High glucose induces Drp1-mediated mitochondrial fission via the Orai1 calcium channel to participate in diabetic cardiomyocyte hypertrophy","volume":"12","author":"Wu","year":"2021","journal-title":"Cell Death Dis"},{"key":"10.1016\/j.jshs.2025.101095_bib0049","doi-asserted-by":"crossref","first-page":"3687","DOI":"10.7150\/thno.33684","article-title":"Targeting mitochondrial dynamics by regulating Mfn2 for therapeutic intervention in diabetic cardiomyopathy","volume":"9","author":"Hu","year":"2019","journal-title":"Theranostics"},{"key":"10.1016\/j.jshs.2025.101095_bib0050","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1159\/000374021","article-title":"Exercise prevents cardiac injury and improves mitochondrial biogenesis in advanced diabetic cardiomyopathy with PGC-1\u03b1 and Akt activation","volume":"35","author":"Wang","year":"2015","journal-title":"Cell Physiol Biochem"},{"key":"10.1016\/j.jshs.2025.101095_bib0051","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.yjmcc.2016.01.023","article-title":"Moderate intensity exercise prevents diabetic cardiomyopathy associated contractile dysfunction through restoration of mitochondrial function and connexin 43 levels in db\/db mice","volume":"92","author":"Veeranki","year":"2016","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.jshs.2025.101095_bib0052","doi-asserted-by":"crossref","first-page":"6275","DOI":"10.3390\/ijms21176275","article-title":"Pathophysiology of type 2 diabetes mellitus","volume":"21","author":"Galicia-Garcia","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jshs.2025.101095_bib0053","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1186\/s12944-017-0473-y","article-title":"Perilipins: A diversity of intracellular lipid droplet proteins","volume":"16","author":"Itabe","year":"2017","journal-title":"Lipids Health Dis"},{"key":"10.1016\/j.jshs.2025.101095_bib0054","doi-asserted-by":"crossref","DOI":"10.1016\/j.jlr.2022.100172","article-title":"Lipid droplet-mitochondria coupling via perilipin 5 augments respiratory capacity but is dispensable for FA oxidation","volume":"63","author":"Kien","year":"2022","journal-title":"J Lipid Res"},{"key":"10.1016\/j.jshs.2025.101095_bib0055","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s00418-011-0888-x","article-title":"The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria","volume":"137","author":"Bosma","year":"2012","journal-title":"Histochem Cell Biol"},{"key":"10.1016\/j.jshs.2025.101095_bib0056","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1161\/CIRCULATIONAHA.121.053575","article-title":"Altered cardiac energetics and mitochondrial dysfunction in hypertrophic cardiomyopathy","volume":"144","author":"Ranjbarvaziri","year":"2021","journal-title":"Circulation"},{"key":"10.1016\/j.jshs.2025.101095_bib0057","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1161\/CIRCRESAHA.117.311307","article-title":"Mitochondrial reactive oxygen species in lipotoxic hearts induce post-translational modifications of AKAP121, DRP1, and OPA1 that promote mitochondrial fission","volume":"122","author":"Tsushima","year":"2018","journal-title":"Circ Res"},{"key":"10.1016\/j.jshs.2025.101095_bib0058","doi-asserted-by":"crossref","first-page":"2844","DOI":"10.1161\/CIRCULATIONAHA.111.060889","article-title":"Ventricular assist device implantation corrects myocardial lipotoxicity, reverses insulin resistance, and normalizes cardiac metabolism in patients with advanced heart failure","volume":"125","author":"Chokshi","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.jshs.2025.101095_bib0059","doi-asserted-by":"crossref","first-page":"3443","DOI":"10.1172\/JCI40905","article-title":"PPAR\u03b3-induced cardiolipotoxicity in mice is ameliorated by PPAR\u03b1 deficiency despite increases in fatty acid oxidation","volume":"120","author":"Son","year":"2010","journal-title":"J Clin Invest"},{"issue":"Suppl. 1","key":"10.1016\/j.jshs.2025.101095_bib0060","doi-asserted-by":"crossref","first-page":"S22","DOI":"10.5213\/inj.1938038.019","article-title":"Effects of acute exercise on mitochondrial function, dynamics, and mitophagy in rat cardiac and skeletal muscles","volume":"23","author":"Yoo","year":"2019","journal-title":"Int Neurourol J"},{"key":"10.1016\/j.jshs.2025.101095_bib0061","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/s00424-020-02357-6","article-title":"Effects of aging and exercise training on mitochondrial function and apoptosis in the rat heart","volume":"472","author":"No","year":"2020","journal-title":"Pflugers Arch"},{"key":"10.1016\/j.jshs.2025.101095_bib0062","doi-asserted-by":"crossref","first-page":"E519","DOI":"10.1152\/ajpendo.00617.2013","article-title":"Exercise training boosts eNOS-dependent mitochondrial biogenesis in mouse heart: Role in adaptation of glucose metabolism","volume":"306","author":"Vettor","year":"2014","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.jshs.2025.101095_bib0063","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1007\/s00395-011-0213-9","article-title":"Mitochondrial biogenesis and PGC-1\u03b1 deacetylation by chronic treadmill exercise: Differential response in cardiac and skeletal muscle","volume":"106","author":"Li","year":"2011","journal-title":"Basic Res Cardiol"},{"key":"10.1016\/j.jshs.2025.101095_bib0064","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1007\/s13105-019-00705-4","article-title":"One year of exercise training promotes distinct adaptations in right and left ventricle of female Sprague-Dawley rats","volume":"75","author":"Nogueira-Ferreira","year":"2019","journal-title":"J Physiol Biochem"},{"key":"10.1016\/j.jshs.2025.101095_bib0065","doi-asserted-by":"crossref","first-page":"H1100","DOI":"10.1152\/ajpheart.00697.2019","article-title":"Guidelines for animal exercise and training protocols for cardiovascular studies","volume":"318","author":"Poole","year":"2020","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.jshs.2025.101095_bib0066","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.ynstr.2016.09.002","article-title":"Forced treadmill exercise can induce stress and increase neuronal damage in a mouse model of global cerebral ischemia","volume":"5","author":"Svensson","year":"2016","journal-title":"Neurobiol Stress"}],"container-title":["Journal of Sport and Health Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2095254625000778?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2095254625000778?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T12:15:27Z","timestamp":1778847327000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2095254625000778"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":66,"alternative-id":["S2095254625000778"],"URL":"https:\/\/doi.org\/10.1016\/j.jshs.2025.101095","relation":{},"ISSN":["2095-2546"],"issn-type":[{"value":"2095-2546","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Influence of diet-induced obesity and voluntary exercise training on cardiac lipids and mitochondrial function in mice","name":"articletitle","label":"Article Title"},{"value":"Journal of Sport and Health Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jshs.2025.101095","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier B.V. on behalf of Shanghai University of Sport.","name":"copyright","label":"Copyright"}],"article-number":"101095"}}