{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:10:33Z","timestamp":1790665833408,"version":"4.1.0"},"reference-count":84,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","theclinics.com","clinicalkey.com.au","clinicalkey.fr","sleep.theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Sleep Medicine Clinics"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1016\/j.jsmc.2016.05.005","type":"journal-article","created":{"date-parts":[[2016,6,22]],"date-time":"2016-06-22T18:24:16Z","timestamp":1466619856000},"page":"353-363","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"title":["Residual Daytime Sleepiness in Obstructive Sleep Apnea After Continuous Positive Airway Pressure Optimization"],"prefix":"10.1016","volume":"11","author":[{"given":"Julia L.","family":"Chapman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasmina","family":"Serinel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathaniel S.","family":"Marshall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald R.","family":"Grunstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.jsmc.2016.05.005_bib1","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1111\/jsr.12039","article-title":"Residual sleepiness in sleep apnea patients treated by continuous positive airway pressure","volume":"22","author":"Gasa","year":"2013","journal-title":"J\u00a0Sleep Res"},{"issue":"3","key":"10.1016\/j.jsmc.2016.05.005_bib2","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1183\/09031936.00124708","article-title":"Predictors of residual sleepiness in adequately treated obstructive sleep apnoea patients","volume":"34","author":"Koutsourelakis","year":"2009","journal-title":"Eur Respir J"},{"issue":"5","key":"10.1016\/j.jsmc.2016.05.005_bib3","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1183\/09031936.00016808","article-title":"Prevalence of residual excessive sleepiness in CPAP-treated sleep apnoea patients: the French multicentre study","volume":"33","author":"Pepin","year":"2009","journal-title":"Eur Respir J"},{"issue":"2","key":"10.1016\/j.jsmc.2016.05.005_bib4","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1164\/ajrccm.159.2.9804051","article-title":"Relation of sleepiness to respiratory disturbance index: the Sleep Heart Health Study","volume":"159","author":"Gottlieb","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"10.1016\/j.jsmc.2016.05.005_bib5","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1164\/ajrccm.151.5.7735600","article-title":"Snoring and sleep apnea. A population study in Australian men","volume":"151","author":"Bearpark","year":"1995","journal-title":"Am J Respir Crit Care Med"},{"issue":"17","key":"10.1016\/j.jsmc.2016.05.005_bib6","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1056\/NEJM199304293281704","article-title":"The occurrence of sleep-disordered breathing among middle-aged adults","volume":"328","author":"Young","year":"1993","journal-title":"N\u00a0Engl J Med"},{"issue":"4","key":"10.1016\/j.jsmc.2016.05.005_bib7","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/S2213-2600(15)00043-0","article-title":"Prevalence of sleep-disordered breathing in the general population: the HypnoLaus study","volume":"3","author":"Heinzer","year":"2015","journal-title":"Lancet Respir Med"},{"issue":"1","key":"10.1016\/j.jsmc.2016.05.005_bib8","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1111\/j.1445-5994.2007.01395.x","article-title":"Sleep health New South Wales: chronic sleep restriction and daytime sleepiness","volume":"38","author":"Bartlett","year":"2008","journal-title":"Intern Med J"},{"issue":"2","key":"10.1016\/j.jsmc.2016.05.005_bib9","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1093\/sleep\/28.2.249","article-title":"The Epworth Sleepiness Scale: influence of age, ethnicity, and socioeconomic deprivation. Epworth Sleepiness scores of adults in New Zealand","volume":"28","author":"Gander","year":"2005","journal-title":"Sleep"},{"issue":"2","key":"10.1016\/j.jsmc.2016.05.005_bib10","doi-asserted-by":"crossref","first-page":"e5","DOI":"10.1016\/S2213-2600(16)00006-0","article-title":"Prevalence of sleep apnoea syndrome in the middle to old age general population","volume":"4","author":"Heinzer","year":"2016","journal-title":"Lancet Respir Med"},{"issue":"5","key":"10.1016\/j.jsmc.2016.05.005_bib11","doi-asserted-by":"crossref","first-page":"605","DOI":"10.5665\/sleep.1812","article-title":"Daytime sleepiness in obesity: mechanisms beyond obstructive sleep apnea - a review","volume":"35","author":"Panossian","year":"2012","journal-title":"Sleep"},{"issue":"5","key":"10.1016\/j.jsmc.2016.05.005_bib12","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1136\/thx.2005.050583","article-title":"Continuous positive airway pressure reduces daytime sleepiness in mild to moderate obstructive sleep apnoea: a meta-analysis","volume":"61","author":"Marshall","year":"2006","journal-title":"Thorax"},{"issue":"1","key":"10.1016\/j.jsmc.2016.05.005_bib13","article-title":"Continuous positive airways pressure for obstructive sleep apnoea in adults","author":"Giles","year":"2009","journal-title":"Cochrane Database Syst Rev"},{"issue":"2","key":"10.1016\/j.jsmc.2016.05.005_bib14","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1093\/sleep\/27.2.194","article-title":"Long-term intermittent hypoxia in mice: protracted hypersomnolence with oxidative injury to sleep-wake brain regions","volume":"27","author":"Veasey","year":"2004","journal-title":"Sleep"},{"issue":"1","key":"10.1016\/j.jsmc.2016.05.005_bib15","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1183\/09031936.00040410","article-title":"Residual sleepiness in obstructive sleep apnoea: phenotype and related symptoms","volume":"38","author":"Vernet","year":"2011","journal-title":"Eur Respir J"},{"issue":"3","key":"10.1016\/j.jsmc.2016.05.005_bib16","doi-asserted-by":"crossref","first-page":"246","DOI":"10.5664\/JCSM.1062","article-title":"Driving simulator performance remains impaired in patients with severe OSA after CPAP treatment","volume":"7","author":"Vakulin","year":"2011","journal-title":"J\u00a0Clin Sleep Med"},{"issue":"1","key":"10.1016\/j.jsmc.2016.05.005_bib17","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0022-3999(02)00542-1","article-title":"Distinguishing between excessive daytime sleepiness and fatigue: toward improved detection and treatment","volume":"54","author":"Pigeon","year":"2003","journal-title":"J\u00a0Psychosom Res"},{"issue":"1","key":"10.1016\/j.jsmc.2016.05.005_bib18","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1183\/09031936.00009506","article-title":"Daytime sleepiness and polysomnographic variables in sleep apnoea patients","volume":"30","author":"Mediano","year":"2007","journal-title":"Eur Respir J"},{"issue":"12","key":"10.1016\/j.jsmc.2016.05.005_bib19","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1164\/rccm.200411-1564OC","article-title":"Inducible nitric oxide synthase in long-term intermittent hypoxia: hypersomnolence and brain injury","volume":"171","author":"Zhan","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"issue":"10","key":"10.1016\/j.jsmc.2016.05.005_bib20","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1164\/rccm.201005-0693OC","article-title":"Obstructive sleep apnea: brain structural changes and neurocognitive function before and after treatment","volume":"183","author":"Canessa","year":"2011","journal-title":"Am J Respir Crit Care Med"},{"issue":"6","key":"10.1016\/j.jsmc.2016.05.005_bib21","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1093\/sleep\/14.6.540","article-title":"A\u00a0new method for measuring daytime sleepiness: the Epworth Sleepiness Scale","volume":"14","author":"Johns","year":"1991","journal-title":"Sleep"},{"issue":"10","key":"10.1016\/j.jsmc.2016.05.005_bib22","first-page":"835","article-title":"An instrument to measure functional status outcomes for disorders of excessive sleepiness","volume":"20","author":"Weaver","year":"1997","journal-title":"Sleep"},{"issue":"6","key":"10.1016\/j.jsmc.2016.05.005_bib23","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/0013-4694(82)90142-0","article-title":"Maintenance of wakefulness test: a polysomnographic technique for evaluating treatment efficacy in patients with excessive somnolence","volume":"53","author":"Mitler","year":"1982","journal-title":"Electroencephalogr Clin Neurophysiol"},{"issue":"4","key":"10.1016\/j.jsmc.2016.05.005_bib24","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1093\/sleep\/9.4.519","article-title":"Guidelines for the Multiple Sleep Latency Test (MSLT): a standard measure of sleepiness","volume":"9","author":"Carskadon","year":"1987","journal-title":"Sleep"},{"issue":"8","key":"10.1016\/j.jsmc.2016.05.005_bib25","first-page":"620","article-title":"Value of the Multiple Sleep Latency Test (MSLT) for the diagnosis of narcolepsy","volume":"20","author":"Aldrich","year":"1997","journal-title":"Sleep"},{"issue":"2","key":"10.1016\/j.jsmc.2016.05.005_bib26","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/S0031-9384(96)80048-5","article-title":"Can normal subjects be motivated to fall asleep faster?","volume":"60","author":"Harrison","year":"1996","journal-title":"Physiol Behav"},{"issue":"4","key":"10.1016\/j.jsmc.2016.05.005_bib27","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1378\/chest.101.4.898","article-title":"Maintenance of wakefulness test and multiple sleep latency test; measurement of different abilities in patients with sleep disorders","volume":"101","author":"Sangal","year":"1992","journal-title":"Chest"},{"issue":"3","key":"10.1016\/j.jsmc.2016.05.005_bib28","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.smrv.2007.02.005","article-title":"Persistent sleepiness in CPAP treated obstructive sleep apnea patients: evaluation and treatment","volume":"11","author":"Santamaria","year":"2007","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.jsmc.2016.05.005_bib29","series-title":"Principles and practice of sleep medicine","first-page":"1125","article-title":"Positive airway pressure treatment for obstructive sleep apnea","author":"Freedman","year":"2017"},{"issue":"4","key":"10.1016\/j.jsmc.2016.05.005_bib30","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1183\/09031936.04.00133703","article-title":"Bench testing of auto-adjusting positive airway pressure devices","volume":"24","author":"Abdenbi","year":"2004","journal-title":"Eur Respir J"},{"issue":"6","key":"10.1016\/j.jsmc.2016.05.005_bib31","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1183\/09031936.00093811","article-title":"Residual sleep-disordered breathing during autotitrating continuous positive airway pressure therapy","volume":"39","author":"Denotti","year":"2012","journal-title":"Eur Respir J"},{"issue":"3","key":"10.1016\/j.jsmc.2016.05.005_bib32","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1378\/chest.07-2602","article-title":"Determination of therapeutic continuous positive airway pressure for obstructive sleep apnea using automatic titration: promises not fulfilled","volume":"133","author":"Rodenstein","year":"2008","journal-title":"Chest"},{"issue":"3","key":"10.1016\/j.jsmc.2016.05.005_bib33","doi-asserted-by":"crossref","first-page":"263","DOI":"10.5664\/jcsm.27497","article-title":"Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults","volume":"5","author":"Epstein","year":"2009","journal-title":"J\u00a0Clin Sleep Med"},{"issue":"1\u20132","key":"10.1016\/j.jsmc.2016.05.005_bib34","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.jns.2015.10.017","article-title":"Sleep hygiene and its association with daytime sleepiness, depressive symptoms, and quality of life in patients with mild\u00a0obstructive sleep apnea","volume":"359","author":"Lee","year":"2015","journal-title":"J\u00a0Neurol Sci"},{"issue":"1","key":"10.1016\/j.jsmc.2016.05.005_bib35","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.sleh.2014.12.010","article-title":"National Sleep Foundation sleep time duration recommendations: methodology and results summary","volume":"1","author":"Hirshkowitz","year":"2013","journal-title":"Sleep Health"},{"issue":"1","key":"10.1016\/j.jsmc.2016.05.005_bib36","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S0022-3999(02)00443-9","article-title":"Prevalence of restless legs syndrome and periodic limb movement disorder in the general population","volume":"53","author":"Ohayon","year":"2002","journal-title":"J\u00a0Psychosom Res"},{"issue":"11","key":"10.1016\/j.jsmc.2016.05.005_bib37","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1001\/archinte.165.11.1286","article-title":"Restless legs syndrome prevalence and impact: rest general population study","volume":"165","author":"Allen","year":"2005","journal-title":"Arch Intern Med"},{"issue":"8","key":"10.1016\/j.jsmc.2016.05.005_bib38","doi-asserted-by":"crossref","first-page":"4510","DOI":"10.1210\/jc.2005-0035","article-title":"Excessive daytime sleepiness in a general population sample: the role of sleep apnea, age, obesity, diabetes, and depression","volume":"90","author":"Bixler","year":"2005","journal-title":"J\u00a0Clin Endocrinol Metab"},{"issue":"3","key":"10.1016\/j.jsmc.2016.05.005_bib39","doi-asserted-by":"crossref","first-page":"212","DOI":"10.4088\/JCP.v62n0314a","article-title":"The clinical features of bipolar depression: a comparison with matched major depressive disorder patients","volume":"62","author":"Mitchell","year":"2001","journal-title":"J\u00a0Clin Psychiatry"},{"issue":"5","key":"10.1016\/j.jsmc.2016.05.005_bib40","first-page":"469","article-title":"Pathophysiology of seasonal affective disorder: a review","volume":"25","author":"Lam","year":"2000","journal-title":"J\u00a0Psychiatry Neurosci"},{"issue":"6","key":"10.1016\/j.jsmc.2016.05.005_bib41","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.smrv.2009.04.001","article-title":"Obstructive sleep apnea and depression","volume":"13","author":"Harris","year":"2009","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.jsmc.2016.05.005_bib42","series-title":"GABA and\u00a0sleep: molecular, functional and clinical aspects","first-page":"121","article-title":"Sleep and its modulation by substances\u00a0that affect GABAA receptor function","author":"Steiger","year":"2010"},{"issue":"24","key":"10.1016\/j.jsmc.2016.05.005_bib43","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.2165\/00003495-200363240-00003","article-title":"Excessive daytime sleepiness and sleep disturbances in patients with neurological diseases: epidemiology and management","volume":"63","author":"Happe","year":"2003","journal-title":"Drugs"},{"issue":"3","key":"10.1016\/j.jsmc.2016.05.005_bib44","doi-asserted-by":"crossref","first-page":"351","DOI":"10.5665\/sleep.4488","article-title":"Natural history of excessive daytime sleepiness: role of obesity, weight loss, depression, and sleep propensity","volume":"38","author":"Fernandez-Mendoza","year":"2015","journal-title":"Sleep"},{"key":"10.1016\/j.jsmc.2016.05.005_bib45","doi-asserted-by":"crossref","first-page":"a801","DOI":"10.1136\/bmj.a801","article-title":"Management of hypothyroidism in adults","volume":"337","author":"Vaidya","year":"2008","journal-title":"BMJ"},{"issue":"3","key":"10.1016\/j.jsmc.2016.05.005_bib46","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1210\/jcem.85.3.6484","article-title":"Sleep apnea and daytime sleepiness and fatigue: relation to visceral obesity, insulin resistance, and hypercytokinemia","volume":"85","author":"Vgontzas","year":"2000","journal-title":"J\u00a0Clin Endocrinol Metab"},{"issue":"5","key":"10.1016\/j.jsmc.2016.05.005_bib47","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1210\/jcem.82.5.3950","article-title":"Elevation of plasma cytokines in disorders of excessive daytime sleepiness: role of sleep disturbance and obesity","volume":"82","author":"Vgontzas","year":"1997","journal-title":"J\u00a0Clin Endocrinol Metab"},{"issue":"10","key":"10.1016\/j.jsmc.2016.05.005_bib48","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1136\/thoraxjnl-2012-201622","article-title":"The effect of continuous positive airway pressure usage on sleepiness in obstructive sleep apnoea: real effects or expectation of benefit?","volume":"67","author":"Crawford","year":"2012","journal-title":"Thorax"},{"issue":"2","key":"10.1016\/j.jsmc.2016.05.005_bib49","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.smrv.2013.03.002","article-title":"Integrating psychology and medicine in CPAP adherence \u2013 new concepts?","volume":"18","author":"Crawford","year":"2014","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.jsmc.2016.05.005_bib50","series-title":"Viral infections of humans: epidemiology and control","first-page":"867","article-title":"Epstein-Barr virus (EBV): infectious mononucleosis and other non-malignant EBV-associated diseases","author":"Macsween","year":"2014"},{"issue":"2","key":"10.1016\/j.jsmc.2016.05.005_bib51","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.ecl.2007.03.002","article-title":"Androgens, obesity, and sleep-disordered breathing in men","volume":"36","author":"Liu","year":"2007","journal-title":"Endocrinol Metab Clin North Am"},{"issue":"6","key":"10.1016\/j.jsmc.2016.05.005_bib52","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1093\/sleep\/31.6.824","article-title":"Two randomized placebo-controlled trials to evaluate the efficacy and tolerability of mirtazapine for the treatment of obstructive sleep apnea","volume":"31","author":"Marshall","year":"2008","journal-title":"Sleep"},{"key":"10.1016\/j.jsmc.2016.05.005_bib53","series-title":"Nuvigil (armodafinil) medication guide","year":"2013"},{"key":"10.1016\/j.jsmc.2016.05.005_bib54","series-title":"Provigil (modafinil) medication guide","year":"2015"},{"issue":"9","key":"10.1016\/j.jsmc.2016.05.005_bib55","doi-asserted-by":"crossref","first-page":"613","DOI":"10.2165\/11315280-000000000-00000","article-title":"Armodafinil and modafinil have substantially different pharmacokinetic profiles despite having the same terminal half-lives: analysis of data from three randomized, single-dose, pharmacokinetic studies","volume":"29","author":"Darwish","year":"2009","journal-title":"Clin Drug Investig"},{"issue":"10","key":"10.1016\/j.jsmc.2016.05.005_bib56","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1016\/j.biopsych.2010.08.026","article-title":"A\u00a0positron emission tomography study examining the dopaminergic activity of armodafinil in adults using [11C]altropane and [11C]raclopride","volume":"68","author":"Spencer","year":"2010","journal-title":"Biol Psychiatry"},{"issue":"2","key":"10.1016\/j.jsmc.2016.05.005_bib57","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1124\/jpet.106.106583","article-title":"Modafinil occupies dopamine and norepinephrine transporters in\u00a0vivo and modulates the transporters and trace amine activity in\u00a0vitro","volume":"319","author":"Madras","year":"2006","journal-title":"J\u00a0Pharmacol Exp Ther"},{"issue":"6","key":"10.1016\/j.jsmc.2016.05.005_bib58","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/j.bcp.2009.10.004","article-title":"Good night and good luck: norepinephrine in sleep pharmacology","volume":"79","author":"Mitchell","year":"2010","journal-title":"Biochem Pharmacol"},{"issue":"7063","key":"10.1016\/j.jsmc.2016.05.005_bib59","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1038\/nature04284","article-title":"Hypothalamic regulation of sleep and circadian rhythms","volume":"437","author":"Saper","year":"2005","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.jsmc.2016.05.005_bib60","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1124\/pr.112.007054","article-title":"Psychostimulants and cognition: a continuum of behavioral and cognitive activation","volume":"66","author":"Wood","year":"2014","journal-title":"Pharmacol Rev"},{"issue":"10","key":"10.1016\/j.jsmc.2016.05.005_bib61","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.5664\/jcsm.5096","article-title":"Effect of wakefulness-promoting agents on sleepiness in patients with sleep apnea treated with CPAP: a meta-analysis","volume":"11","author":"Sukhal","year":"2015","journal-title":"J\u00a0Clin Sleep Med"},{"key":"10.1016\/j.jsmc.2016.05.005_bib62","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.01509-2015","article-title":"Modafinil\/armodafinil in obstructive sleep apnoea: a systematic review and meta-analysis","author":"Chapman","year":"2016","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jsmc.2016.05.005_bib63","unstructured":"Commonwealth of Australia Therapeutic Goods Administration; public Australian register of therapeutic goods summary for modafinil Australia. 2011. Available\u00a0at: https:\/\/www.ebs.tga.gov.au\/servlet\/xmlmillr6?dbid=ebs\/PublicHTML\/pdfStore.nsf&docid=82350&agid=(PrintDetailsPublic)&actionid=1. Accessed February 25, 2016."},{"key":"10.1016\/j.jsmc.2016.05.005_bib64","unstructured":"Cephalon Inc. Approved by the US Food and Drug Administration Medication Guide - Provigil (modafinil) tablets. USA: 2010. Available at: http:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2010\/020717s030s034s036MedGuide.pdf. Accessed February 25, 2016."},{"key":"10.1016\/j.jsmc.2016.05.005_bib65","unstructured":"European Medicines Agency. Questions and answers on the review of medicines containing modafinil. London (United Kingdom): 2010. Available at:\u00a0http:\/\/www.ema.europa.eu\/ema\/index.jsp?curl=pages\/medicines\/human\/referrals\/Modafinil\/human_referral_000236.jsp. Accessed February 22, 2016."},{"key":"10.1016\/j.jsmc.2016.05.005_bib66","unstructured":"Australian Register of Therapeutic Goods ID 226561-NUVIGIL armodafinil 50 mg. 2016. Available at: https:\/\/www.tga.gov.au\/artg\/artg-id-226561. Accessed February 22, 2016."},{"issue":"2","key":"10.1016\/j.jsmc.2016.05.005_bib67","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1164\/rccm.2209006","article-title":"Pro: modafinil has a role in management of sleep apnea","volume":"167","author":"Black","year":"2003","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"10.1016\/j.jsmc.2016.05.005_bib68","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1164\/rccm.2209008","article-title":"Con: modafinil has no role in management of sleep apnea","volume":"167","author":"Pollak","year":"2003","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"10.1016\/j.jsmc.2016.05.005_bib69","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1164\/rccm.2211007","article-title":"Should a pharmaceutical be approved for the broad indication of excessive sleepiness?","volume":"167","author":"Pack","year":"2003","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jsmc.2016.05.005_bib70","unstructured":"European Medicines Agency. Assessment report for modafinil containing medicinal products. London (United Kingdom): 2011. Available at: http:\/\/www.ema.europa.eu\/ema\/index.jsp?curl=pages\/medicines\/human\/referrals\/Modafinil\/human_referral_000236.jsp. Accessed February 22, 2016."},{"issue":"12","key":"10.1016\/j.jsmc.2016.05.005_bib71","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1093\/sleep\/30.12.1705","article-title":"Practice parameters for the treatment of narcolepsy and other hypersomnias of central origin","volume":"30","author":"Morgenthaler","year":"2007","journal-title":"Sleep"},{"key":"10.1016\/j.jsmc.2016.05.005_bib72","series-title":"Phentermine hydrochloride and topiramate extended-release medication guide","year":"2014"},{"issue":"11","key":"10.1016\/j.jsmc.2016.05.005_bib73","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.5665\/sleep.2204","article-title":"A\u00a0randomized, double-blind, placebo-controlled study of an oral, extended-release formulation of phentermine\/topiramate for the treatment of obstructive sleep apnea in obese adults","volume":"35","author":"Winslow","year":"2012","journal-title":"Sleep"},{"issue":"3","key":"10.1016\/j.jsmc.2016.05.005_bib74","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1046\/j.1365-2869.2000.00209.x","article-title":"Does caffeine confound relationships among adrenergic tone, blood pressure and sleep apnoea?","volume":"9","author":"Bardwell","year":"2000","journal-title":"J\u00a0Sleep Res"},{"issue":"3","key":"10.1016\/j.jsmc.2016.05.005_bib75","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1378\/chest.11-2894","article-title":"Sleep-disordered breathing and caffeine consumption: results of a community-based study","volume":"142","author":"Aurora","year":"2012","journal-title":"Chest"},{"issue":"3","key":"10.1016\/j.jsmc.2016.05.005_bib76","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/s11325-007-0153-7","article-title":"Caffeine intake is independently associated with neuropsychological performance in patients with obstructive sleep apnea","volume":"12","author":"Norman","year":"2008","journal-title":"Sleep Breath"},{"issue":"3","key":"10.1016\/j.jsmc.2016.05.005_bib77","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1007\/s002130100916","article-title":"Maintaining alertness and performance during sleep deprivation: modafinil versus caffeine","volume":"159","author":"Wesensten","year":"2002","journal-title":"Psychopharmacology"},{"issue":"6","key":"10.1016\/j.jsmc.2016.05.005_bib78","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.3945\/ajcn.110.004044","article-title":"Habitual coffee consumption and risk of hypertension: a systematic review and meta-analysis of prospective observational studies","volume":"93","author":"Zhang","year":"2011","journal-title":"Am J Clin Nutr"},{"issue":"5","key":"10.1016\/j.jsmc.2016.05.005_bib79","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1097\/01.hjh.0000166828.94699.1d","article-title":"Blood\u00a0pressure response to chronic intake of coffee and caffeine: a meta-analysis of randomized controlled trials","volume":"23","author":"Noordzij","year":"2005","journal-title":"J\u00a0Hypertens"},{"issue":"5","key":"10.1016\/j.jsmc.2016.05.005_bib80","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1038\/sj.clpt.6100102","article-title":"A\u00a0genetic variation in the adenosine A2A receptor gene (ADORA2A) contributes to individual sensitivity to caffeine effects on sleep","volume":"81","author":"R\u00e9tey","year":"2007","journal-title":"Clin Pharmacol Ther"},{"issue":"9","key":"10.1016\/j.jsmc.2016.05.005_bib81","doi-asserted-by":"crossref","first-page":"4409","DOI":"10.1210\/jc.2003-031929","article-title":"Marked decrease in sleepiness in patients with sleep apnea by etanercept, a tumor necrosis factor-alpha antagonist","volume":"89","author":"Vgontzas","year":"2004","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.jsmc.2016.05.005_bib82","series-title":"Enbrel (etanercept) prescribing information","year":"2013"},{"issue":"11","key":"10.1016\/j.jsmc.2016.05.005_bib83","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1016\/S1474-4422(13)70225-4","article-title":"Pitolisant versus placebo or modafinil in patients with narcolepsy: a double-blind, randomised trial","volume":"12","author":"Dauvilliers","year":"2013","journal-title":"Lancet Neurol"},{"issue":"16","key":"10.1016\/j.jsmc.2016.05.005_bib84","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1007\/s40265-013-0127-y","article-title":"Current and emerging options for the drug treatment of narcolepsy","volume":"73","author":"De la Herran-Arita","year":"2013","journal-title":"Drugs"}],"container-title":["Sleep Medicine Clinics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1556407X16300406?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1556407X16300406?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T20:12:08Z","timestamp":1718655128000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1556407X16300406"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9]]},"references-count":84,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["S1556407X16300406"],"URL":"https:\/\/doi.org\/10.1016\/j.jsmc.2016.05.005","relation":{},"ISSN":["1556-407X"],"issn-type":[{"value":"1556-407X","type":"print"}],"subject":[],"published":{"date-parts":[[2016,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Residual Daytime Sleepiness in Obstructive Sleep Apnea After Continuous Positive Airway Pressure Optimization","name":"articletitle","label":"Article Title"},{"value":"Sleep Medicine Clinics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jsmc.2016.05.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}