{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T14:22:03Z","timestamp":1793110923588,"version":"4.5.0"},"reference-count":101,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","theclinics.com","clinicalkey.fr","clinicalkey.com.au","sleep.theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Sleep Medicine Clinics"],"published-print":{"date-parts":[[2018,3]]},"DOI":"10.1016\/j.jsmc.2017.09.003","type":"journal-article","created":{"date-parts":[[2017,11,10]],"date-time":"2017-11-10T18:32:34Z","timestamp":1510338754000},"page":"21-37","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Apnea in Older Adults"],"prefix":"10.1016","volume":"13","author":[{"given":"Susmita","family":"Chowdhuri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pragnesh","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Safwan","family":"Badr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jsmc.2017.09.003_bib1","unstructured":"The World Health Organization. World report on ageing and health. 2015. Available at: http:\/\/www.who.int\/ageing\/en\/. Accessed January 30, 2017."},{"issue":"4","key":"10.1016\/j.jsmc.2017.09.003_bib2","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1093\/geronj\/36.4.420","article-title":"Respiration during sleep in the aged human","volume":"36","author":"Carskadon","year":"1981","journal-title":"J\u00a0Gerontol"},{"issue":"6","key":"10.1016\/j.jsmc.2017.09.003_bib3","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1093\/sleep\/14.6.486","article-title":"Sleep-disordered breathing in community-dwelling elderly","volume":"14","author":"Ancoli-Israel","year":"1991","journal-title":"Sleep"},{"issue":"6","key":"10.1016\/j.jsmc.2017.09.003_bib4","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1093\/sleep\/13.6.502","article-title":"Comparison of sleep-disordered breathing among healthy elderly in the seventh, eighth, and ninth decades of life","volume":"13","author":"Hoch","year":"1990","journal-title":"Sleep"},{"issue":"1","key":"10.1016\/j.jsmc.2017.09.003_bib5","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1164\/ajrccm.157.1.9706079","article-title":"Effects of age on sleep apnea in men: I. Prevalence and severity","volume":"157","author":"Bixler","year":"1998","journal-title":"Am J Respir Crit Care Med"},{"issue":"3 Pt 1","key":"10.1016\/j.jsmc.2017.09.003_bib6","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1164\/ajrccm.163.3.2005065","article-title":"Obstructive sleep apnea-hypopnea and related clinical features in a population-based sample of subjects aged 30 to 70 yr","volume":"163","author":"Duran","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"10.1016\/j.jsmc.2017.09.003_bib7","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1164\/ajrccm.163.3.9911064","article-title":"Prevalence of sleep-disordered breathing in women: effects of gender","volume":"163","author":"Bixler","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"issue":"9","key":"10.1016\/j.jsmc.2017.09.003_bib8","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1111\/j.1532-5415.2007.01290.x","article-title":"Prevalence and correlates of sleep-disordered breathing in older men: osteoporotic fractures in men sleep study","volume":"55","author":"Mehra","year":"2007","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"17","key":"10.1016\/j.jsmc.2017.09.003_bib9","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1056\/NEJM199304293281704","article-title":"The occurrence of sleep-disordered breathing among middle-aged adults","volume":"328","author":"Young","year":"1993","journal-title":"N\u00a0Engl J Med"},{"issue":"2","key":"10.1016\/j.jsmc.2017.09.003_bib10","doi-asserted-by":"crossref","first-page":"e2293","DOI":"10.1097\/MD.0000000000002293","article-title":"Increased risk of Parkinson's disease in patients with obstructive sleep apnea: a population-based, propensity score-matched, longitudinal follow-up study","volume":"95","author":"Yeh","year":"2016","journal-title":"Medicine (Baltimore)"},{"issue":"6","key":"10.1016\/j.jsmc.2017.09.003_bib11","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1093\/sleep\/26.6.703","article-title":"Predictors of longitudinal change in sleep-disordered breathing in a nonclinic population","volume":"26","author":"Redline","year":"2003","journal-title":"Sleep"},{"issue":"8","key":"10.1016\/j.jsmc.2017.09.003_bib12","first-page":"1071","article-title":"Sleep disordered breathing and mortality: eighteen-year follow-up of the Wisconsin sleep cohort","volume":"31","author":"Young","year":"2008","journal-title":"Sleep"},{"issue":"7","key":"10.1016\/j.jsmc.2017.09.003_bib13","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1093\/gerona\/63.7.715","article-title":"Prevalence of sleep disturbances in a cohort of older drivers","volume":"63","author":"Fragoso","year":"2008","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.jsmc.2017.09.003_bib14","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.2147\/COPD.S67779","article-title":"The prevalence of obstructive sleep apnea-hypopnea syndrome-related symptoms and their relation to airflow limitation in an elderly population receiving home care","volume":"9","author":"Kleisiaris","year":"2014","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"issue":"1","key":"10.1016\/j.jsmc.2017.09.003_bib15","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1007\/s11325-012-0700-8","article-title":"Limits of the Epworth sleepiness scale in older adults","volume":"17","author":"Onen","year":"2013","journal-title":"Sleep Breath"},{"issue":"10","key":"10.1016\/j.jsmc.2017.09.003_bib16","doi-asserted-by":"crossref","first-page":"2001","DOI":"10.1111\/jgs.13660","article-title":"Underperception of naps in older adults referred for a sleep assessment: an insomnia trait and a cognitive problem?","volume":"63","author":"Nguyen-Michel","year":"2015","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"11","key":"10.1016\/j.jsmc.2017.09.003_bib17","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.5664\/jcsm.3162","article-title":"Prevalence and symptoms of occult sleep disordered breathing among older veterans with insomnia","volume":"9","author":"Fung","year":"2013","journal-title":"J\u00a0Clin Sleep Med"},{"issue":"8","key":"10.1016\/j.jsmc.2017.09.003_bib18","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1001\/archinte.162.8.893","article-title":"Predictors of sleep-disordered breathing in community-dwelling adults: the sleep heart health study","volume":"162","author":"Young","year":"2002","journal-title":"Arch Intern Med"},{"issue":"4","key":"10.1016\/j.jsmc.2017.09.003_bib19","doi-asserted-by":"crossref","first-page":"501","DOI":"10.5665\/sleep.2532","article-title":"Relation of central fat mass to obstructive sleep apnea in the elderly","volume":"36","author":"Degache","year":"2013","journal-title":"Sleep"},{"key":"10.1016\/j.jsmc.2017.09.003_bib20","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/s40064-016-1672-0","article-title":"Assessing the risk of obstructive sleep apnoea-hypopnoea syndrome in elderly home care patients with chronic multimorbidity: a cross-sectional screening study","volume":"5","author":"Kleisiaris","year":"2016","journal-title":"Springerplus"},{"issue":"3","key":"10.1016\/j.jsmc.2017.09.003_bib21","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1093\/sleep\/4.3.283","article-title":"Comparisons of home sleep recordings and polysomnograms in older adults with sleep disorders","volume":"4","author":"Ancoli-Israel","year":"1981","journal-title":"Sleep"},{"issue":"11","key":"10.1016\/j.jsmc.2017.09.003_bib22","first-page":"1491","article-title":"In-home, self-assembled sleep studies are useful in diagnosing sleep apnea in the elderly","volume":"35","author":"Morales","year":"2012","journal-title":"Sleep"},{"issue":"3","key":"10.1016\/j.jsmc.2017.09.003_bib23","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1152\/jappl.1988.64.3.1257","article-title":"Spectral analysis of ventilation in elderly subjects awake and asleep","volume":"64","author":"Pack","year":"1988","journal-title":"J\u00a0Appl Physiol (1985)"},{"issue":"3","key":"10.1016\/j.jsmc.2017.09.003_bib24","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1152\/jappl.1992.72.3.985","article-title":"Correlation between oscillations in ventilation and frequency content of the electroencephalogram","volume":"72","author":"Pack","year":"1992","journal-title":"J\u00a0Appl Physiol (1985)"},{"key":"10.1016\/j.jsmc.2017.09.003_bib25","article-title":"Aging is associated with Increased Propensity for Central Apnea during NREM Sleep","author":"Chowdhuri","year":"2017","journal-title":"J Appl Physiol (1985)"},{"issue":"Pt\u00a01","key":"10.1016\/j.jsmc.2017.09.003_bib26","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1113\/jphysiol.2006.126409","article-title":"Chemical control stability in the elderly","volume":"581","author":"Wellman","year":"2007","journal-title":"J\u00a0Physiol"},{"issue":"5","key":"10.1016\/j.jsmc.2017.09.003_bib27","doi-asserted-by":"crossref","first-page":"2209","DOI":"10.1152\/jappl.1993.75.5.2209","article-title":"Ventilatory sensitivity to CO2 in hyperoxia and hypoxia in older aged humans","volume":"75","author":"Poulin","year":"1993","journal-title":"J\u00a0Appl Physiol (1985)"},{"issue":"2","key":"10.1016\/j.jsmc.2017.09.003_bib28","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1093\/geronj\/42.2.202","article-title":"Aging effects on the interaction of hypercapnia and hypoxia as ventilatory stimuli","volume":"42","author":"Chapman","year":"1987","journal-title":"J\u00a0Gerontol"},{"issue":"3","key":"10.1016\/j.jsmc.2017.09.003_bib29","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1183\/09031936.03.00039002","article-title":"Ageing does not influence the sleep-related decrease in the hypercapnic ventilatory response","volume":"21","author":"Browne","year":"2003","journal-title":"Eur Respir J"},{"issue":"10","key":"10.1016\/j.jsmc.2017.09.003_bib30","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1152\/japplphysiol.00030.2015","article-title":"Effect of age on long-term facilitation and chemosensitivity during NREM sleep","volume":"119","author":"Chowdhuri","year":"2015","journal-title":"J\u00a0Appl Physiol (1985)"},{"issue":"6","key":"10.1016\/j.jsmc.2017.09.003_bib31","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1093\/cercor\/bhq224","article-title":"Alterations in cerebral metabolic rate and blood supply across the adult lifespan","volume":"21","author":"Lu","year":"2011","journal-title":"Cereb Cortex"},{"issue":"3","key":"10.1016\/j.jsmc.2017.09.003_bib32","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1080\/10739680701641421","article-title":"Age-related alterations in reactivity of cerebral arterioles: role of oxidative stress","volume":"15","author":"Mayhan","year":"2008","journal-title":"Microcirculation"},{"issue":"6","key":"10.1016\/j.jsmc.2017.09.003_bib33","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/S0301-0082(99)00009-X","article-title":"Respiratory network function in the isolated brainstem-spinal cord of newborn rats","volume":"59","author":"Ballanyi","year":"1999","journal-title":"Prog Neurobiol"},{"issue":"9","key":"10.1016\/j.jsmc.2017.09.003_bib34","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1183\/09031936.97.10092087","article-title":"The effect of age, sex, obesity and posture on upper airway size","volume":"10","author":"Martin","year":"1997","journal-title":"Eur Respir J"},{"issue":"72","key":"10.1016\/j.jsmc.2017.09.003_bib35","first-page":"e79","article-title":"Aging influences on pharyngeal anatomy and physiology: the predisposition to pharyngeal collapse","volume":"119(1)","author":"Malhotra","year":"2006","journal-title":"Am J Med"},{"issue":"6","key":"10.1016\/j.jsmc.2017.09.003_bib36","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.1378\/chest.06-2653","article-title":"The influence of aging on pharyngeal collapsibility during sleep","volume":"131","author":"Eikermann","year":"2007","journal-title":"Chest"},{"issue":"4 Pt 1","key":"10.1016\/j.jsmc.2017.09.003_bib37","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1164\/ajrccm\/145.4_Pt_1.846","article-title":"Fast-computed tomography evaluation of age-related changes in upper airway structure and function in normal men","volume":"145","author":"Burger","year":"1992","journal-title":"Am Rev Respir Dis"},{"issue":"Suppl 1","key":"10.1016\/j.jsmc.2017.09.003_bib38","first-page":"14","article-title":"Age-related response of the genioglossus muscle EMG-activity to hypoxia in humans","volume":"54","author":"Klawe","year":"2003","journal-title":"J\u00a0Physiol Pharmacol"},{"issue":"7","key":"10.1016\/j.jsmc.2017.09.003_bib39","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.5665\/sleep.3844","article-title":"Obstructive sleep apnea in older adults is a distinctly different physiological phenotype","volume":"37","author":"Edwards","year":"2014","journal-title":"Sleep"},{"issue":"11","key":"10.1016\/j.jsmc.2017.09.003_bib40","doi-asserted-by":"crossref","first-page":"2050","DOI":"10.2337\/dc15-0137","article-title":"Sleep disturbances and glucose metabolism in older adults: the cardiovascular health study","volume":"38","author":"Strand","year":"2015","journal-title":"Diabetes Care"},{"issue":"6","key":"10.1016\/j.jsmc.2017.09.003_bib41","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1016\/j.mehy.2005.10.033","article-title":"Ischemic preconditioning as a possible explanation for the age decline relative mortality in sleep apnea","volume":"66","author":"Lavie","year":"2006","journal-title":"Med Hypotheses"},{"issue":"5","key":"10.1016\/j.jsmc.2017.09.003_bib42","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1161\/01.CIR.0000154540.62381.CF","article-title":"Age-dependent associations between sleep-disordered breathing and hypertension importance of discriminating between systolic\/diastolic hypertension and isolated systolic hypertension in the sleep heart health study","volume":"111","author":"Haas","year":"2005","journal-title":"Circulation"},{"issue":"7","key":"10.1016\/j.jsmc.2017.09.003_bib43","first-page":"1009","article-title":"The cardiovascular response to arousal from sleep decreases with age in healthy adults","volume":"31","author":"Goff","year":"2008","journal-title":"Sleep"},{"issue":"9","key":"10.1016\/j.jsmc.2017.09.003_bib44","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/j.sleep.2013.05.002","article-title":"Association between severe obstructive sleep apnea and incident arterial hypertension in the older people population","volume":"14","author":"Guillot","year":"2013","journal-title":"Sleep Med"},{"issue":"4","key":"10.1016\/j.jsmc.2017.09.003_bib45","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1161\/HYPERTENSIONAHA.111.174409","article-title":"Decreased slow wave sleep increases risk of developing hypertension in elderly men","volume":"58","author":"Fung","year":"2011","journal-title":"Hypertension"},{"issue":"14","key":"10.1016\/j.jsmc.2017.09.003_bib46","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1001\/jama.283.14.1829","article-title":"Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study","volume":"283","author":"Nieto","year":"2000","journal-title":"JAMA"},{"issue":"19","key":"10.1016\/j.jsmc.2017.09.003_bib47","doi-asserted-by":"crossref","first-page":"2034","DOI":"10.1056\/NEJMoa043104","article-title":"Obstructive sleep apnea as a risk factor for stroke and death","volume":"353","author":"Yaggi","year":"2005","journal-title":"N\u00a0Engl J Med"},{"issue":"8","key":"10.1016\/j.jsmc.2017.09.003_bib48","doi-asserted-by":"crossref","first-page":"e1000132","DOI":"10.1371\/journal.pmed.1000132","article-title":"Sleep-disordered breathing and mortality: a prospective cohort study","volume":"6","author":"Punjabi","year":"2009","journal-title":"PLoS Med"},{"issue":"4","key":"10.1016\/j.jsmc.2017.09.003_bib49","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1161\/CIRCULATIONAHA.109.901801","article-title":"Prospective study of obstructive sleep apnea and incident coronary heart disease and heart failure: the sleep heart health study","volume":"122","author":"Gottlieb","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.jsmc.2017.09.003_bib50","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s12882-016-0229-3","article-title":"Sleep disordered breathing and cardiovascular risk in older patients initiating dialysis in the United States: a retrospective observational study using Medicare data","volume":"17","author":"Tuohy","year":"2016","journal-title":"BMC Nephrol"},{"issue":"3","key":"10.1016\/j.jsmc.2017.09.003_bib51","doi-asserted-by":"crossref","first-page":"523","DOI":"10.5665\/sleep.5518","article-title":"Association between obstructive sleep apnea and left ventricular structure by age and gender: the multi-ethnic study of atherosclerosis","volume":"39","author":"Javaheri","year":"2016","journal-title":"Sleep"},{"issue":"4","key":"10.1016\/j.jsmc.2017.09.003_bib52","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1378\/chest.124.4.1400","article-title":"The relationship between congestive heart failure, sleep apnea, and mortality in older men","volume":"124","author":"Ancoli-Israel","year":"2003","journal-title":"Chest"},{"issue":"9","key":"10.1016\/j.jsmc.2017.09.003_bib53","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1164\/rccm.201203-0448OC","article-title":"Cardiovascular mortality in obstructive sleep apnea in the elderly: role of long-term continuous positive airway pressure treatment: a prospective observational study","volume":"186","author":"Mart\u00ednez-Garc\u00eda","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"issue":"4","key":"10.1016\/j.jsmc.2017.09.003_bib54","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1093\/sleep\/34.4.435","article-title":"Sleep disordered breathing with excessive daytime sleepiness is a risk factor for mortality in older adults","volume":"34","author":"Gooneratne","year":"2011","journal-title":"Sleep"},{"issue":"5","key":"10.1016\/j.jsmc.2017.09.003_bib55","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1164\/rccm.201503-0536OC","article-title":"Sleep-disordered breathing and incident heart failure in older men","volume":"193","author":"Javaheri","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"issue":"12","key":"10.1016\/j.jsmc.2017.09.003_bib56","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1001\/archinternmed.2009.138","article-title":"Nocturnal arrhythmias across a spectrum of obstructive and central sleep-disordered breathing in older men: outcomes of sleep disorders in older men (MrOS sleep) study","volume":"169","author":"Mehra","year":"2009","journal-title":"Arch Intern Med"},{"issue":"7","key":"10.1016\/j.jsmc.2017.09.003_bib57","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1164\/rccm.201508-1523OC","article-title":"Central sleep-disordered breathing predicts incident atrial fibrillation in older men","volume":"193","author":"May","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"10.1016\/j.jsmc.2017.09.003_bib58","first-page":"531","article-title":"Sleep disordered breathing and risk of stroke in older community-dwelling men","volume":"39","author":"Stone","year":"2015","journal-title":"Sleep"},{"issue":"9","key":"10.1016\/j.jsmc.2017.09.003_bib59","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.1161\/01.STR.0000236560.15735.0f","article-title":"Severe sleep apnea and risk of ischemic stroke in the elderly","volume":"37","author":"Munoz","year":"2006","journal-title":"Stroke"},{"issue":"6","key":"10.1016\/j.jsmc.2017.09.003_bib60","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1001\/jama.2011.1115","article-title":"Sleep-disordered breathing, hypoxia, and risk of mild cognitive impairment and dementia in older women","volume":"306","author":"Yaffe","year":"2011","journal-title":"JAMA"},{"key":"10.1016\/j.jsmc.2017.09.003_bib61","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.sleep.2016.02.008","article-title":"A\u00a0review of neurocognitive function and obstructive sleep apnea with or without daytime sleepiness","volume":"23","author":"Zhou","year":"2016","journal-title":"Sleep Med"},{"issue":"1","key":"10.1016\/j.jsmc.2017.09.003_bib62","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s11325-007-0133-y","article-title":"Comparison of cognitive performance among different age groups in patients with obstructive sleep apnea","volume":"12","author":"Alchanatis","year":"2008","journal-title":"Sleep Breath"},{"issue":"1","key":"10.1016\/j.jsmc.2017.09.003_bib63","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0022-3999(02)00548-2","article-title":"Neuropsychological changes and treatment compliance in older adults with sleep apnea","volume":"54","author":"Aloia","year":"2003","journal-title":"J\u00a0Psychosom Res"},{"issue":"4","key":"10.1016\/j.jsmc.2017.09.003_bib64","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1093\/sleep\/33.4.515","article-title":"Cognitive function and sleep related breathing disorders in a healthy elderly population: the SYNAPSE study","volume":"33","author":"Sforza","year":"2010","journal-title":"Sleep"},{"issue":"3","key":"10.1016\/j.jsmc.2017.09.003_bib65","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/jgs.13321","article-title":"Associations between sleep-disordered breathing, nocturnal hypoxemia, and subsequent cognitive decline in older community-dwelling men: the osteoporotic fractures in men sleep study","volume":"63","author":"Blackwell","year":"2015","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"2","key":"10.1016\/j.jsmc.2017.09.003_bib66","doi-asserted-by":"crossref","first-page":"179","DOI":"10.5665\/sleep.4392","article-title":"Sleep breathing disorders and cognitive function in the elderly: an 8-year follow-up study. the proof-synapse cohort","volume":"38","author":"Martin","year":"2015","journal-title":"Sleep"},{"key":"10.1016\/j.jsmc.2017.09.003_bib67","doi-asserted-by":"crossref","first-page":"e99","DOI":"10.1016\/j.rehab.2016.07.221","article-title":"Sleep breathing disorders and cognitive decline in healthy elderly followed for eight years: the PROOF cohort","volume":"59S","author":"Martin","year":"2016","journal-title":"Ann Phys Rehabil Med"},{"issue":"1","key":"10.1016\/j.jsmc.2017.09.003_bib68","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/j.1532-5415.2007.01506.x","article-title":"Sleep-disordered breathing and cognition in older women","volume":"56","author":"Spira","year":"2008","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"6","key":"10.1016\/j.jsmc.2017.09.003_bib69","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1111\/j.1532-5415.2012.03961.x","article-title":"Effects of sleep apnea syndrome on delayed memory and executive function in elderly adults","volume":"60","author":"Ju","year":"2012","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"4","key":"10.1016\/j.jsmc.2017.09.003_bib70","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1111\/ggi.12768","article-title":"Factors associated with the severity of obstructive sleep apnea in older adults","volume":"17","author":"Hongyo","year":"2017","journal-title":"Geriatr Gerontol Int"},{"issue":"4","key":"10.1016\/j.jsmc.2017.09.003_bib71","doi-asserted-by":"crossref","first-page":"785","DOI":"10.5665\/sleep.5628","article-title":"Sleep disordered breathing and white matter hyperintensities in community-dwelling elders","volume":"39","author":"Rostanski","year":"2016","journal-title":"Sleep"},{"issue":"11","key":"10.1016\/j.jsmc.2017.09.003_bib72","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1164\/rccm.201606-1271OC","article-title":"Gray matter hypertrophy and thickening with obstructive sleep apnea in middle-aged and older adults","volume":"195","author":"Baril","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"10.1016\/j.jsmc.2017.09.003_bib73","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1007\/s12640-013-9379-2","article-title":"Death by a thousand cuts in Alzheimer's disease: hypoxia\u2013the prodrome","volume":"24","author":"Daulatzai","year":"2013","journal-title":"Neurotox Res"},{"issue":"4","key":"10.1016\/j.jsmc.2017.09.003_bib74","doi-asserted-by":"crossref","first-page":"915","DOI":"10.5665\/sleep.5654","article-title":"Sleep disturbances and depression in the multi-ethnic study of atherosclerosis","volume":"39","author":"Alc\u00e1ntara","year":"2015","journal-title":"Sleep"},{"issue":"2","key":"10.1016\/j.jsmc.2017.09.003_bib75","doi-asserted-by":"crossref","first-page":"e32585","DOI":"10.17795\/nmsjournal32585","article-title":"The association between obstructive sleep apnea and depression in older adults","volume":"5","author":"Farajzadeh","year":"2016","journal-title":"Nurs Midwifery Stud"},{"issue":"1","key":"10.1016\/j.jsmc.2017.09.003_bib76","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s11325-014-1006-9","article-title":"Sleep disordered breathing, hypoxia and inflammation: associations with sickness behaviour in community dwelling elderly with and without cardiovascular disease","volume":"19","author":"Johansson","year":"2015","journal-title":"Sleep Breath"},{"issue":"2","key":"10.1016\/j.jsmc.2017.09.003_bib77","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S1389-9457(01)00128-9","article-title":"Personality, anxiety and mood traits in patients with sleep-related breathing disorders: effect of reduced daytime alertness","volume":"3","author":"Sforza","year":"2002","journal-title":"Sleep Med"},{"key":"10.1016\/j.jsmc.2017.09.003_bib78","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.sleep.2015.11.007","article-title":"Mood disorders in healthy elderly with obstructive sleep apnea: a gender effect","volume":"19","author":"Sforza","year":"2016","journal-title":"Sleep Med"},{"issue":"1","key":"10.1016\/j.jsmc.2017.09.003_bib79","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.cger.2014.08.023","article-title":"Obstructive sleep apnea and type 2 diabetes in older adults","volume":"31","author":"Moon","year":"2015","journal-title":"Clin Geriatr Med"},{"issue":"11","key":"10.1016\/j.jsmc.2017.09.003_bib80","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.1111\/jgs.13108","article-title":"Sleep-disordered breathing and functional decline in older women","volume":"62","author":"Spira","year":"2014","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"3","key":"10.1016\/j.jsmc.2017.09.003_bib81","doi-asserted-by":"crossref","first-page":"e349","DOI":"10.1016\/j.archger.2012.02.006","article-title":"Prevalence and predictors of healthcare utilization among older people (60+): focusing on ADL dependency and risk of depression","volume":"54","author":"Sandberg","year":"2012","journal-title":"Arch Gerontol Geriatr"},{"issue":"2","key":"10.1016\/j.jsmc.2017.09.003_bib82","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1111\/j.1532-5415.2007.01544.x","article-title":"The effect of obstructive sleep apnea on morbidity and health care utilization of middle-aged and older adults","volume":"56","author":"Tarasiuk","year":"2008","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"2","key":"10.1016\/j.jsmc.2017.09.003_bib83","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1007\/BF02895774","article-title":"Sleep apnea and health-related quality of life in African-American elderly","volume":"22","author":"Stepnowsky","year":"2000","journal-title":"Ann Behav Med"},{"issue":"1","key":"10.1016\/j.jsmc.2017.09.003_bib84","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.sleep.2007.11.009","article-title":"Obstructive sleep apnea has little impact on quality of life in the elderly","volume":"10","author":"Mart\u00ednez-Garc\u00eda","year":"2009","journal-title":"Sleep Med"},{"issue":"7","key":"10.1016\/j.jsmc.2017.09.003_bib85","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1016\/j.rmed.2005.10.019","article-title":"The determinants of therapeutic levels of continuous positive airway pressure in elderly sleep apnea patients","volume":"100","author":"Kostikas","year":"2006","journal-title":"Respir Med"},{"issue":"2","key":"10.1016\/j.jsmc.2017.09.003_bib86","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1097\/01.JGP.0000192484.12684.cd","article-title":"Adherence to continuous positive airway pressure treatment in patients with Alzheimer disease and obstructive sleep apnea","volume":"14","author":"Ayalon","year":"2006","journal-title":"Am J Geriatr Psychiatry"},{"issue":"5","key":"10.1016\/j.jsmc.2017.09.003_bib87","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1111\/j.1532-5415.2006.00694.x","article-title":"Continuous positive airway pressure reduces subjective daytime sleepiness in patients with mild to moderate Alzheimer's disease with sleep disordered breathing","volume":"54","author":"Chong","year":"2006","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"3","key":"10.1016\/j.jsmc.2017.09.003_bib88","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S1389-9457(00)00063-0","article-title":"The age and other factors in the evaluation of compliance with nasal continuous positive airway pressure for obstructive sleep apnea syndrome. A Cox's proportional hazard analysis","volume":"2","author":"Pelletier-Fleury","year":"2001","journal-title":"Sleep Med"},{"issue":"9","key":"10.1016\/j.jsmc.2017.09.003_bib89","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1046\/j.1532-5415.2001.49238.x","article-title":"Compliance with CPAP therapy in older men with obstructive sleep apnea","volume":"49","author":"Russo-Magno","year":"2001","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"1","key":"10.1016\/j.jsmc.2017.09.003_bib90","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1055\/s-2001-12789","article-title":"Improving compliance with nasal CPAP and vigilance in older adults with OSAHS","volume":"5","author":"Aloia","year":"2001","journal-title":"Sleep Breath"},{"issue":"9464","key":"10.1016\/j.jsmc.2017.09.003_bib91","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1016\/S0140-6736(05)74229-X","article-title":"Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study","volume":"365","author":"Marin","year":"2005","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.jsmc.2017.09.003_bib92","doi-asserted-by":"crossref","first-page":"115","DOI":"10.7326\/0003-4819-156-2-201201170-00006","article-title":"Cardiovascular mortality in women with obstructive sleep apnea with or without continuous positive airway pressure treatment: a cohort study","volume":"156","author":"Campos-Rodriguez","year":"2012","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jsmc.2017.09.003_bib93","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.sleep.2015.10.015","article-title":"Continuous positive airway pressure and survival of very elderly persons with moderate to severe obstructive sleep apnea","volume":"19","author":"L\u00f3pez-Padilla","year":"2016","journal-title":"Sleep Med"},{"issue":"10","key":"10.1016\/j.jsmc.2017.09.003_bib94","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1016\/S2213-2600(14)70172-9","article-title":"Continuous positive airway pressure in older people with obstructive sleep apnoea syndrome (PREDICT): a 12-month, multicentre, randomised trial","volume":"2","author":"McMillan","year":"2014","journal-title":"Lancet Respir Med"},{"issue":"11","key":"10.1016\/j.jsmc.2017.09.003_bib95","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1016\/j.clinthera.2016.09.008","article-title":"Perceived effectiveness, self-efficacy, and social support for oral appliance therapy among older veterans with obstructive sleep apnea","volume":"38","author":"Carballo","year":"2016","journal-title":"Clin Ther"},{"issue":"2","key":"10.1016\/j.jsmc.2017.09.003_bib96","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1093\/gerona\/gln011","article-title":"Sleep-disordered breathing and 24-hour blood pressure pattern among older adults","volume":"64","author":"Endeshaw","year":"2009","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"issue":"6","key":"10.1016\/j.jsmc.2017.09.003_bib97","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1093\/sleep\/18.6.433","article-title":"Four-year follow-up of mortality and sleep-related respiratory disturbance in non-demented seniors","volume":"18","author":"Mant","year":"1995","journal-title":"Sleep"},{"issue":"1","key":"10.1016\/j.jsmc.2017.09.003_bib98","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1164\/rccm.200808-1341OC","article-title":"Continuous positive airway pressure treatment reduces mortality in patients with ischemic stroke and obstructive sleep apnea: a 5-year follow-up study","volume":"180","author":"Martinez-Garcia","year":"2009","journal-title":"Am J Respir Crit Care Med"},{"issue":"4","key":"10.1016\/j.jsmc.2017.09.003_bib99","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1093\/ageing\/afs019","article-title":"Clinical characteristics and mortality risk in relation to obstructive and central sleep apnoea in community-dwelling elderly individuals: a 7-year follow-up","volume":"41","author":"Johansson","year":"2012","journal-title":"Age Ageing"},{"issue":"5","key":"10.1016\/j.jsmc.2017.09.003_bib100","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.ahj.2014.12.024","article-title":"Impact of obstructive sleep apnea and continuous positive airway pressure therapy on outcomes in patients with atrial fibrillation-results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF)","volume":"169","author":"Holmqvist","year":"2015","journal-title":"Am Heart J"},{"issue":"7","key":"10.1016\/j.jsmc.2017.09.003_bib101","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.5665\/sleep.2802","article-title":"Sleep fragmentation and the risk of incident Alzheimer's disease and cognitive decline in older persons","volume":"36","author":"Lim","year":"2013","journal-title":"Sleep"}],"container-title":["Sleep Medicine Clinics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1556407X17301042?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1556407X17301042?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,10,21]],"date-time":"2020-10-21T16:36:20Z","timestamp":1603298180000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1556407X17301042"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":101,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["S1556407X17301042"],"URL":"https:\/\/doi.org\/10.1016\/j.jsmc.2017.09.003","relation":{},"ISSN":["1556-407X"],"issn-type":[{"value":"1556-407X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Apnea in Older Adults","name":"articletitle","label":"Article Title"},{"value":"Sleep Medicine Clinics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jsmc.2017.09.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}