{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T15:44:20Z","timestamp":1784735060274,"version":"3.55.0"},"reference-count":79,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","sleep.theclinics.com","clinicalkey.jp","theclinics.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Sleep Medicine Clinics"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.jsmc.2024.02.003","type":"journal-article","created":{"date-parts":[[2024,3,7]],"date-time":"2024-03-07T20:43:00Z","timestamp":1709844180000},"page":"229-237","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Hypoxic and Autonomic Mechanisms from Sleep-Disordered Breathing Leading to Cardiopulmonary Dysfunction"],"prefix":"10.1016","volume":"19","author":[{"given":"Avantika","family":"Nathani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Attaway","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reena","family":"Mehra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.jsmc.2024.02.003_bib2","article-title":"The economic burden of comorbid obstructive sleep apnea among patients with chronic obstructive pulmonary disease","volume":"26","author":"Hong","year":"2020","journal-title":"J\u00a0Manag Care Spec Pharm"},{"key":"10.1016\/j.jsmc.2024.02.003_bib3","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.767982","article-title":"Risk for cardiovascular disease and one-year mortality in patients with chronic obstructive pulmonary disease and obstructive sleep apnea syndrome overlap syndrome","volume":"12","author":"Tang","year":"2021","journal-title":"Front Pharmacol"},{"issue":"1","key":"10.1016\/j.jsmc.2024.02.003_bib4","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/eci.12011","article-title":"Comorbidities and survival in obstructive sleep apnoea beyond the age of 50","volume":"43","author":"Marrone","year":"2013","journal-title":"Eur J Clin Invest"},{"issue":"1","key":"10.1016\/j.jsmc.2024.02.003_bib5","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1378\/chest.14-0500","article-title":"Intermittent hypoxemia and OSA: implications for comorbidities","volume":"147","author":"Dewan","year":"2015","journal-title":"Chest"},{"issue":"21","key":"10.1016\/j.jsmc.2024.02.003_bib6","doi-asserted-by":"crossref","first-page":"2462","DOI":"10.1161\/01.CIR.0000018948.95175.03","article-title":"Elevated C-reactive protein in patients with obstructive sleep apnea","volume":"105","author":"Shamsuzzaman","year":"2002","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.jsmc.2024.02.003_bib7","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1080\/07853890.2022.2081873","article-title":"The causal relationships between obstructive sleep apnea and elevated CRP and TNF-\u03b1 protein levels","volume":"54","author":"Yi","year":"2022","journal-title":"Ann Med"},{"issue":"5","key":"10.1016\/j.jsmc.2024.02.003_bib8","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1536\/ihj.46.801","article-title":"Elevated C-reactive protein levels and increased cardiovascular risk in patients with obstructive sleep apnea syndrome","volume":"46","author":"Kokturk","year":"2005","journal-title":"Int Heart J"},{"issue":"7","key":"10.1016\/j.jsmc.2024.02.003_bib9","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1164\/rccm.200601-066OC","article-title":"Predictors of elevated nuclear factor-kappaB-dependent genes in obstructive sleep apnea syndrome","volume":"174","author":"Ryan","year":"2006","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"10.1016\/j.jsmc.2024.02.003_bib10","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1378\/chest.126.5.1473","article-title":"Elevated production of tumor necrosis factor-alpha by monocytes in patients with obstructive sleep apnea syndrome","volume":"126","author":"Minoguchi","year":"2004","journal-title":"Chest"},{"issue":"1","key":"10.1016\/j.jsmc.2024.02.003_bib11","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1186\/s12890-020-01253-0","article-title":"Association between tumor necrosis factor alpha and obstructive sleep apnea in adults: a meta-analysis update","volume":"20","author":"Cao","year":"2020","journal-title":"BMC Pulm Med"},{"issue":"Suppl 56","key":"10.1016\/j.jsmc.2024.02.003_bib12","article-title":"Plasma levels of TNF in obstructive sleep apnea syndrome (OSA) before and after surgical intervention","volume":"40","author":"Reyad","year":"2012","journal-title":"Eur Respir J"},{"issue":"2","key":"10.1016\/j.jsmc.2024.02.003_bib13","doi-asserted-by":"crossref","first-page":"10650","DOI":"10.1080\/21655979.2021.2001203","article-title":"Interleukin-8 concentrations in obstructive sleep apnea syndrome: a systematic review and meta-analysis","volume":"12","author":"Li","year":"2021","journal-title":"Bioengineered"},{"issue":"1","key":"10.1016\/j.jsmc.2024.02.003_bib14","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/s13223-019-0338-1","article-title":"Enhanced interleukin-8 production in mononuclear cells in severe pediatric obstructive sleep apnea","volume":"15","author":"Ke","year":"2019","journal-title":"Allergy Asthma Clin Immunol"},{"issue":"6","key":"10.1016\/j.jsmc.2024.02.003_bib15","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1164\/rccm.201001-0020OC","article-title":"Sleep-disordered breathing and prothrombotic biomarkers: cross-sectional results of the Cleveland Family Study","volume":"182","author":"Mehra","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"10.1016\/j.jsmc.2024.02.003_bib16","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1055\/s-0034-1390023","article-title":"Obstructive sleep apnea: role of intermittent hypoxia and inflammation","volume":"35","author":"May","year":"2014","journal-title":"Semin Respir Crit Care Med"},{"issue":"10","key":"10.1016\/j.jsmc.2024.02.003_bib17","doi-asserted-by":"crossref","first-page":"5042","DOI":"10.1172\/JCI137560","article-title":"Hypoxia-inducible factors and obstructive sleep apnea","volume":"130","author":"Prabhakar","year":"2020","journal-title":"J\u00a0Clin Invest"},{"issue":"Pt 1","key":"10.1016\/j.jsmc.2024.02.003_bib18","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1113\/jphysiol.2006.112524","article-title":"Chronic intermittent hypoxia induces hypoxia-evoked catecholamine efflux in adult rat adrenal medulla via oxidative stress","volume":"575","author":"Kumar","year":"2006","journal-title":"J\u00a0Physiol"},{"issue":"4","key":"10.1016\/j.jsmc.2024.02.003_bib19","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/S0272-5231(21)00402-0","article-title":"Sleep in chronic obstructive lung disease","volume":"6","author":"Flenley","year":"1985","journal-title":"Clin Chest Med"},{"key":"10.1016\/j.jsmc.2024.02.003_bib20","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.smrv.2016.02.007","article-title":"Current evidence on prevalence and clinical outcomes of co-morbid obstructive sleep apnea and chronic obstructive pulmonary disease: a systematic review","volume":"32","author":"Shawon","year":"2017","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.jsmc.2024.02.003_bib21","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.sleep.2023.10.011","article-title":"Mortality in obstructive sleep apnea syndrome (OSAS) and overlap syndrome (OS): the role of nocturnal hypoxemia and CPAP compliance","volume":"112","author":"Tondo","year":"2023","journal-title":"Sleep Med"},{"issue":"1","key":"10.1016\/j.jsmc.2024.02.003_bib22","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s12890-021-01780-4","article-title":"Predictors and outcomes of obstructive sleep apnea in patients with chronic obstructive pulmonary disease in China","volume":"22","author":"Zhang","year":"2022","journal-title":"BMC Pulm Med"},{"issue":"2","key":"10.1016\/j.jsmc.2024.02.003_bib23","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1136\/thx.2007.088930","article-title":"Isolated nocturnal desaturation in COPD: prevalence and impact on quality of life and sleep","volume":"64","author":"Lewis","year":"2009","journal-title":"Thorax"},{"issue":"1","key":"10.1016\/j.jsmc.2024.02.003_bib24","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1186\/s12931-021-01868-9","article-title":"Characteristics of the nocturnal desaturation waveform pattern of SpO2 in COPD patients: an observational study","volume":"22","author":"Yoshizaki","year":"2021","journal-title":"Respir Res"},{"issue":"9","key":"10.1016\/j.jsmc.2024.02.003_bib25","first-page":"1257","article-title":"Ventilatory responses to hypercapnia during wakefulness and sleep in obese adolescents with and without obstructive sleep apnea syndrome","volume":"35","author":"Yuan","year":"2012","journal-title":"Sleep"},{"issue":"3","key":"10.1016\/j.jsmc.2024.02.003_bib26","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1164\/rccm.200912-1869OC","article-title":"Outcomes in patients with chronic obstructive pulmonary disease and obstructive sleep apnea","volume":"182","author":"Marin","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"10.1016\/j.jsmc.2024.02.003_bib27","doi-asserted-by":"crossref","first-page":"9085","DOI":"10.1038\/s41598-023-34956-5","article-title":"Association between smoking and obstructive sleep apnea based on the STOP-Bang index","volume":"13","author":"Jang","year":"2023","journal-title":"Sci Rep"},{"issue":"3","key":"10.1016\/j.jsmc.2024.02.003_bib28","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1093\/ntr\/ntac126","article-title":"Association between smoking behavior and obstructive sleep apnea: a systematic review and meta-analysis","volume":"25","author":"Zeng","year":"2023","journal-title":"Nicotine Tob Res"},{"issue":"2","key":"10.1016\/j.jsmc.2024.02.003_bib29","doi-asserted-by":"crossref","first-page":"293","DOI":"10.3390\/jpm12020293","article-title":"Smoking obstructive sleep apnea: arguments for a distinctive phenotype and a personalized intervention","volume":"12","author":"O\u021belea","year":"2022","journal-title":"J\u00a0Personalized Med"},{"issue":"3","key":"10.1016\/j.jsmc.2024.02.003_bib30","first-page":"525","article-title":"Long-term cardiopulmonary sequelae in patients with sleep apnea and chronic lung disease","volume":"135","author":"Fletcher","year":"1987","journal-title":"Am Rev Respir Dis"},{"issue":"3","key":"10.1016\/j.jsmc.2024.02.003_bib31","first-page":"148","article-title":"Pulmonary haemodynamics in patients with OSAS or an overlap syndrome","volume":"61","author":"Hawry\u0142kiewicz","year":"2004","journal-title":"Monaldi Arch Chest Dis Arch Monaldi Mal Torace"},{"issue":"1","key":"10.1016\/j.jsmc.2024.02.003_bib32","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1164\/ajrccm.151.1.7812577","article-title":"Association of chronic obstructive pulmonary disease and sleep apnea syndrome","volume":"151","author":"Chaouat","year":"1995","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"10.1016\/j.jsmc.2024.02.003_bib33","first-page":"129","article-title":"Risk of new-onset atrial fibrillation in elderly patients with the overlap syndrome: a retrospective cohort study","volume":"10","author":"Ganga","year":"2013","journal-title":"J\u00a0Geriatr Cardiol JGC"},{"key":"10.1016\/j.jsmc.2024.02.003_bib34","doi-asserted-by":"crossref","first-page":"665","DOI":"10.2147\/COPD.S148735","article-title":"Obstructive sleep apnea, COPD, the overlap syndrome, and mortality: results from the 2005-2008 National Health and Nutrition Examination Survey","volume":"13","author":"Du","year":"2018","journal-title":"Int J Chronic Obstr Pulm Dis"},{"issue":"4","key":"10.1016\/j.jsmc.2024.02.003_bib35","doi-asserted-by":"crossref","first-page":"e74","DOI":"10.1164\/rccm.202006-2382ST","article-title":"Long-Term Noninvasive Ventilation in Chronic Stable Hypercapnic Chronic Obstructive Pulmonary Disease. An Official American Thoracic Society Clinical Practice Guideline","volume":"202","author":"Macrea","year":"2020","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jsmc.2024.02.003_bib36","series-title":"C66. \u201cWALK this way\u201d - update on exercise tests and pulmonary rehabilitation. American thoracic society international conference abstracts","first-page":"A5745","article-title":"A\u00a0screening tool to predict obstructive sleep apnea in patients with chronic obstructive pulmonary disease: a pilot study of the UCSD COPD-OSA questionnaire","author":"Soler","year":"2016"},{"issue":"9","key":"10.1016\/j.jsmc.2024.02.003_bib37","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1096\/fba.2021-00024","article-title":"A\u00a0review of therapies for the overlap syndrome of obstructive sleep apnea and chronic obstructive pulmonary disease","volume":"3","author":"Suri","year":"2021","journal-title":"FASEB BioAdvances"},{"issue":"5","key":"10.1016\/j.jsmc.2024.02.003_bib38","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1378\/chest.07-1527","article-title":"Nocturnal noninvasive ventilation","volume":"133","author":"Ozsancak","year":"2008","journal-title":"Chest"},{"issue":"2","key":"10.1016\/j.jsmc.2024.02.003_bib39","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1164\/rccm.202109-2035OC","article-title":"Impact of positive airway pressure therapy adherence on outcomes in patients with obstructive sleep apnea and chronic obstructive pulmonary disease","volume":"206","author":"Sterling","year":"2022","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jsmc.2024.02.003_bib40","doi-asserted-by":"crossref","first-page":"F1000","DOI":"10.12688\/f1000research.18811.1","article-title":"The 6th world symposium on pulmonary hypertension: what\u2019s old is new","volume":"8","author":"Condon","year":"2019","journal-title":"F1000Research"},{"issue":"2","key":"10.1016\/j.jsmc.2024.02.003_bib41","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1378\/chest.109.2.380","article-title":"Pulmonary hemodynamics in the obstructive sleep apnea syndrome. results in 220 consecutive patients","volume":"109","author":"Chaouat","year":"1996","journal-title":"Chest"},{"issue":"5","key":"10.1016\/j.jsmc.2024.02.003_bib42","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.pcad.2008.06.001","article-title":"Obstructive sleep apnea and pulmonary hypertension","volume":"51","author":"Sajkov","year":"2009","journal-title":"Prog Cardiovasc Dis"},{"issue":"2","key":"10.1016\/j.jsmc.2024.02.003_bib43","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1378\/chest.120.2.369","article-title":"The obesity-hypoventilation syndrome revisited: a prospective study of 34 consecutive cases","volume":"120","author":"Kessler","year":"2001","journal-title":"Chest"},{"issue":"1","key":"10.1016\/j.jsmc.2024.02.003_bib44","doi-asserted-by":"crossref","first-page":"2002258","DOI":"10.1183\/13993003.02258-2020","article-title":"Sleep-related breathing disorders and pulmonary hypertension","volume":"57","author":"Adir","year":"2021","journal-title":"Eur Respir J"},{"issue":"3","key":"10.1016\/j.jsmc.2024.02.003_bib45","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1053\/smrv.2001.0185","article-title":"Pulmonary haemodynamics in obstructive sleep apnoea","volume":"6","author":"Marrone","year":"2002","journal-title":"Sleep Med Rev"},{"issue":"1","key":"10.1016\/j.jsmc.2024.02.003_bib46","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.chest.2016.09.001","article-title":"Hypoxic pulmonary vasoconstriction","volume":"151","author":"Dunham-Snary","year":"2017","journal-title":"Chest"},{"issue":"5","key":"10.1016\/j.jsmc.2024.02.003_bib47","doi-asserted-by":"crossref","first-page":"R1014","DOI":"10.1152\/ajpregu.00124.2004","article-title":"Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology","volume":"287","author":"Li","year":"2004","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"2","key":"10.1016\/j.jsmc.2024.02.003_bib48","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.sleep.2012.10.020","article-title":"Chronic intermittent hypoxia down-regulates endothelial nitric oxide synthase expression by an NF-\u03baB-dependent mechanism","volume":"14","author":"Wang","year":"2013","journal-title":"Sleep Med"},{"issue":"3","key":"10.1016\/j.jsmc.2024.02.003_bib49","doi-asserted-by":"crossref","first-page":"e58078","DOI":"10.1371\/journal.pone.0058078","article-title":"Effects of cyclic intermittent hypoxia on ET-1 responsiveness and endothelial dysfunction of pulmonary arteries in rats","volume":"8","author":"Wang","year":"2013","journal-title":"PloS One"},{"issue":"8","key":"10.1016\/j.jsmc.2024.02.003_bib50","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.5664\/jcsm.8468","article-title":"Pulmonary artery hemodynamics are associated with duration of nocturnal desaturation but not apnea-hypopnea index","volume":"16","author":"Samhouri","year":"2020","journal-title":"J\u00a0Clin Sleep Med"},{"issue":"2","key":"10.1016\/j.jsmc.2024.02.003_bib51","doi-asserted-by":"crossref","first-page":"213","DOI":"10.5664\/jcsm.10286","article-title":"Implication of prolonged nocturnal hypoxemia and obstructive sleep apnea for pulmonary hemodynamics in patients being evaluated for pulmonary hypertension: a retrospective study","volume":"19","author":"Huang","year":"2023","journal-title":"J\u00a0Clin Sleep Med"},{"issue":"Supplement_1","key":"10.1016\/j.jsmc.2024.02.003_bib52","doi-asserted-by":"crossref","first-page":"A367","DOI":"10.1093\/sleep\/zsad077.0834","article-title":"0834 Association of sleep disordered breathing and hemodynamics of world symposium on pulmonary hypertension groups in PVDOMICS cohort","volume":"46","author":"Musco","year":"2023","journal-title":"Sleep"},{"issue":"21","key":"10.1016\/j.jsmc.2024.02.003_bib53","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1016\/j.jacc.2023.09.806","article-title":"Sleep-related hypoxia, right ventricular dysfunction, and survival in patients with group 1 pulmonary arterial hypertension","volume":"82","author":"Lowery","year":"2023","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"38","key":"10.1016\/j.jsmc.2024.02.003_bib54","doi-asserted-by":"crossref","first-page":"3618","DOI":"10.1093\/eurheartj\/ehac237","article-title":"2022 ESC\/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension","volume":"43","author":"Humbert","year":"2022","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jsmc.2024.02.003_bib55","doi-asserted-by":"crossref","first-page":"107339","DOI":"10.1016\/j.rmed.2023.107339","article-title":"STOP-Bang for OSA screening in patients with pulmonary hypertension","volume":"217","author":"Fox","year":"2023","journal-title":"Respir Med"},{"issue":"11","key":"10.1016\/j.jsmc.2024.02.003_bib56","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1136\/thorax.55.11.934","article-title":"Pulmonary arterial hypertension in patients with sleep apnoea syndrome","volume":"55","author":"Bady","year":"2000","journal-title":"Thorax"},{"issue":"3","key":"10.1016\/j.jsmc.2024.02.003_bib57","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/s00408-003-1017-y","article-title":"Pulmonary hemodynamics in obstructive sleep apnea: frequency and causes of pulmonary hypertension","volume":"181","author":"Hetzel","year":"2003","journal-title":"Lung"},{"issue":"5","key":"10.1016\/j.jsmc.2024.02.003_bib58","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1111\/resp.12314","article-title":"Continuous positive airway pressure is associated with a decrease in pulmonary artery pressure in patients with obstructive sleep apnoea: a meta-analysis","volume":"19","author":"Sun","year":"2014","journal-title":"Respirol Carlton Vic"},{"issue":"5","key":"10.1016\/j.jsmc.2024.02.003_bib59","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1007\/s10741-016-9548-5","article-title":"Effect of continuous positive airway pressure treatment on pulmonary artery pressure in patients with isolated obstructive sleep apnea: a meta-analysis","volume":"21","author":"Imran","year":"2016","journal-title":"Heart Fail Rev"},{"issue":"2","key":"10.1016\/j.jsmc.2024.02.003_bib60","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1164\/ajrccm.165.2.2010092","article-title":"Continuous positive airway pressure treatment improves pulmonary hemodynamics in patients with obstructive sleep apnea","volume":"165","author":"Sajkov","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"10.1016\/j.jsmc.2024.02.003_bib61","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1164\/ajrccm.163.1.2001008","article-title":"Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study","volume":"163","author":"Shahar","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"10.1016\/j.jsmc.2024.02.003_bib62","doi-asserted-by":"crossref","first-page":"e56","DOI":"10.1161\/CIR.0000000000000988","article-title":"Obstructive sleep apnea and cardiovascular disease: a scientific statement from the american heart association","volume":"144","author":"Yeghiazarians","year":"2021","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.jsmc.2024.02.003_bib63","doi-asserted-by":"crossref","first-page":"e022141","DOI":"10.1161\/JAHA.121.022141","article-title":"Association between arousals during sleep and hypertension among patients with obstructive sleep apnea","volume":"11","author":"Ren","year":"2022","journal-title":"J\u00a0Am Heart Assoc"},{"issue":"2","key":"10.1016\/j.jsmc.2024.02.003_bib64","first-page":"164","article-title":"OSA and atherosclerosis","volume":"4","author":"Lui","year":"2012","journal-title":"J\u00a0Thorac Dis"},{"issue":"7","key":"10.1016\/j.jsmc.2024.02.003_bib65","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1164\/ajrccm.165.7.2104126","article-title":"Increased adhesion molecules expression and production of reactive oxygen species in leukocytes of sleep apnea patients","volume":"165","author":"Dyugovskaya","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jsmc.2024.02.003_bib66","doi-asserted-by":"crossref","first-page":"888644","DOI":"10.3389\/fimmu.2022.888644","article-title":"Causal analysis between altered levels of interleukins and obstructive sleep apnea","volume":"13","author":"Yi","year":"2022","journal-title":"Front Immunol"},{"issue":"6","key":"10.1016\/j.jsmc.2024.02.003_bib67","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1038\/hr.2011.39","article-title":"Oxidative stress and endothelial dysfunction in hypertension","volume":"34","author":"Schulz","year":"2011","journal-title":"Hypertens Res"},{"issue":"9","key":"10.1016\/j.jsmc.2024.02.003_bib68","first-page":"1207","article-title":"Heavy snoring as a cause of carotid artery atherosclerosis","volume":"31","author":"Lee","year":"2008","journal-title":"Sleep"},{"issue":"6","key":"10.1016\/j.jsmc.2024.02.003_bib70","doi-asserted-by":"crossref","first-page":"751","DOI":"10.5665\/SLEEP.1042","article-title":"Tissue vibration induces carotid artery endothelial dysfunction: a mechanism linking snoring and carotid atherosclerosis?","volume":"34","author":"Cho","year":"2011","journal-title":"Sleep"},{"issue":"4","key":"10.1016\/j.jsmc.2024.02.003_bib71","first-page":"230","article-title":"Obstructive sleep apnea, intermittent hypoxemia and prothrombotic biomarkers","volume":"13","author":"Deokar","year":"2020","journal-title":"Sleep Sci"},{"issue":"9","key":"10.1016\/j.jsmc.2024.02.003_bib72","doi-asserted-by":"crossref","first-page":"NP412","DOI":"10.1177\/0145561320965208","article-title":"Prothrombotic factors in obstructive sleep apnea: a systematic review with meta-analysis","volume":"101","author":"Qiu","year":"2022","journal-title":"Ear Nose Throat J"},{"issue":"4","key":"10.1016\/j.jsmc.2024.02.003_bib73","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1007\/s11325-020-02021-4","article-title":"Increased platelet activation in Sleep Apnea subjects with intermittent hypoxemia","volume":"24","author":"Krieger","year":"2020","journal-title":"Sleep Breath Schlaf Atm"},{"issue":"2","key":"10.1016\/j.jsmc.2024.02.003_bib74","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.jacc.2010.08.627","article-title":"Obstructive sleep apnea and heart failure: pathophysiologic and therapeutic implications","volume":"57","author":"Kasai","year":"2011","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"4","key":"10.1016\/j.jsmc.2024.02.003_bib75","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/s11897-006-0020-z","article-title":"The link between obstructive sleep apnea and heart failure: underappreciated opportunity for treatment","volume":"3","author":"Naughton","year":"2006","journal-title":"Curr Heart Fail Rep"},{"issue":"10","key":"10.1016\/j.jsmc.2024.02.003_bib76","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1056\/NEJMoa1606599","article-title":"CPAP for prevention of cardiovascular events in obstructive sleep apnea","volume":"375","author":"McEvoy","year":"2016","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jsmc.2024.02.003_bib77","author":"Tan"},{"issue":"22","key":"10.1016\/j.jsmc.2024.02.003_bib78","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1001\/jama.2013.281250","article-title":"Effect of CPAP on blood pressure in patients with obstructive sleep apnea and resistant hypertension: the HIPARCO randomized clinical trial","volume":"310","author":"Mart\u00ednez-Garc\u00eda","year":"2013","journal-title":"JAMA"},{"issue":"21","key":"10.1016\/j.jsmc.2024.02.003_bib80","doi-asserted-by":"crossref","first-page":"2280","DOI":"10.1001\/jama.2015.16303","article-title":"CPAP vs mandibular advancement devices and blood pressure in patients with obstructive sleep apnea: a systematic review and meta-analysis","volume":"314","author":"Bratton","year":"2015","journal-title":"JAMA"},{"issue":"6","key":"10.1016\/j.jsmc.2024.02.003_bib81","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1111\/resp.12573","article-title":"Effect of CPAP therapy on endothelial function in obstructive sleep apnoea: a systematic review and meta-analysis","volume":"20","author":"Schwarz","year":"2015","journal-title":"Respirol Carlton Vic"},{"issue":"1","key":"10.1016\/j.jsmc.2024.02.003_bib82","first-page":"89","article-title":"CPAP effects on atherosclerotic plaques in patients with sleep-disordered breathing and coronary artery disease: the ENTERPRISE trial","volume":"73","author":"Dohi","year":"2019","journal-title":"J\u00a0Cardiol"}],"container-title":["Sleep Medicine Clinics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1556407X24000134?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1556407X24000134?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,4,29]],"date-time":"2024-04-29T15:10:29Z","timestamp":1714403429000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1556407X24000134"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":79,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["S1556407X24000134"],"URL":"https:\/\/doi.org\/10.1016\/j.jsmc.2024.02.003","relation":{},"ISSN":["1556-407X"],"issn-type":[{"value":"1556-407X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hypoxic and Autonomic Mechanisms from Sleep-Disordered Breathing Leading to Cardiopulmonary Dysfunction","name":"articletitle","label":"Article Title"},{"value":"Sleep Medicine Clinics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jsmc.2024.02.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}