{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T16:18:17Z","timestamp":1790180297810,"version":"4.1.0"},"reference-count":122,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003793","name":"Hj\u00e4rt-Lungfonden","doi-asserted-by":"publisher","award":["20230759"],"award-info":[{"award-number":["20230759"]}],"id":[{"id":"10.13039\/501100003793","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","sleep.theclinics.com","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Sleep Medicine Clinics"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.jsmc.2024.10.002","type":"journal-article","created":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T07:46:37Z","timestamp":1733816797000},"page":"103-114","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Treatable Traits-Based Pharmacologic Treatment of Sleep Apnea"],"prefix":"10.1016","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0220-5961","authenticated-orcid":false,"given":"Daniil","family":"Lisik","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2057-8558","authenticated-orcid":false,"given":"Ding","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.jsmc.2024.10.002_bib1","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/S2213-2600(19)30198-5","article-title":"Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis","volume":"7","author":"Benjafield","year":"2019","journal-title":"Lancet Respir Med"},{"issue":"2","key":"10.1016\/j.jsmc.2024.10.002_bib2","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1513\/pats.200707-114MG","article-title":"Pathophysiology of adult obstructive sleep apnea","volume":"5","author":"Eckert","year":"2008","journal-title":"Proc Am Thorac Soc"},{"key":"10.1016\/j.jsmc.2024.10.002_bib3","doi-asserted-by":"crossref","first-page":"1239016","DOI":"10.3389\/fneur.2023.1239016","article-title":"Translation of obstructive sleep apnea pathophysiology and phenotypes to personalized treatment: a narrative review","volume":"14","author":"McNicholas","year":"2023","journal-title":"Front Neurol"},{"issue":"146","key":"10.1016\/j.jsmc.2024.10.002_bib4","doi-asserted-by":"crossref","DOI":"10.1183\/16000617.0069-2017","article-title":"Personalised medicine in sleep respiratory disorders: focus on obstructive sleep apnoea diagnosis and treatment","volume":"26","author":"Bonsignore","year":"2017","journal-title":"Eur Respir Rev"},{"issue":"6","key":"10.1016\/j.jsmc.2024.10.002_bib5","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1097\/MCP.0000000000000724","article-title":"Endotypes and phenotypes in obstructive sleep apnea","volume":"26","author":"Malhotra","year":"2020","journal-title":"Curr Opin Pulm Med"},{"issue":"1","key":"10.1016\/j.jsmc.2024.10.002_bib6","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1213\/ANE.0000000000001546","article-title":"Understanding phenotypes of obstructive sleep apnea: applications in anesthesia, surgery, and perioperative medicine","volume":"124","author":"Subramani","year":"2017","journal-title":"Anesth Analg"},{"issue":"2","key":"10.1016\/j.jsmc.2024.10.002_bib7","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1055\/s-0036-1579546","article-title":"Comorbidities associated with obstructive sleep apnea: a retrospective study","volume":"20","author":"Pinto","year":"2016","journal-title":"Int Arch Otorhinolaryngol"},{"issue":"2","key":"10.1016\/j.jsmc.2024.10.002_bib8","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.ccm.2019.02.008","article-title":"Pathogenesis of obstructive sleep apnea","volume":"40","author":"Younes","year":"2019","journal-title":"Clin Chest Med"},{"issue":"11","key":"10.1016\/j.jsmc.2024.10.002_bib9","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1164\/rccm.200412-1631SO","article-title":"Pathogenesis of obstructive and central sleep apnea","volume":"172","author":"White","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"issue":"6","key":"10.1016\/j.jsmc.2024.10.002_bib10","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/S1389-9457(01)00072-7","article-title":"Quality of life in obstructive sleep apnea: a systematic review of the literature","volume":"2","author":"Moyer","year":"2001","journal-title":"Sleep Med"},{"issue":"06","key":"10.1016\/j.jsmc.2024.10.002_bib11","doi-asserted-by":"crossref","first-page":"573","DOI":"10.5664\/jcsm.27662","article-title":"Obstructive sleep apnea and risk of motor vehicle crash: systematic review and meta-analysis","volume":"05","author":"Tregear","year":"2009","journal-title":"J\u00a0Clin Sleep Med"},{"issue":"6","key":"10.1016\/j.jsmc.2024.10.002_bib12","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.jacc.2021.05.048","article-title":"Sleep disordered breathing and cardiovascular disease: JACC state-of-the-art review","volume":"78","author":"Cowie","year":"2021","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"3","key":"10.1016\/j.jsmc.2024.10.002_bib13","doi-asserted-by":"crossref","first-page":"e61","DOI":"10.1161\/STR.0000000000000453","article-title":"Impact of sleep disorders and disturbed sleep on brain health: a scientific statement from the American heart association","volume":"55","author":"Gottesman","year":"2024","journal-title":"Stroke"},{"issue":"8","key":"10.1016\/j.jsmc.2024.10.002_bib14","first-page":"1071","article-title":"Sleep disordered breathing and mortality: eighteen-year follow-up of the Wisconsin sleep cohort","volume":"31","author":"Young","year":"2008","journal-title":"Sleep"},{"issue":"5","key":"10.1016\/j.jsmc.2024.10.002_bib15","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1177\/2040622315590318","article-title":"Obstructive sleep apnoea syndrome and its management","volume":"6","author":"Spicuzza","year":"2015","journal-title":"Ther Adv Chronic Dis"},{"issue":"3","key":"10.1016\/j.jsmc.2024.10.002_bib16","doi-asserted-by":"crossref","first-page":"2000144","DOI":"10.1183\/13993003.00144-2020","article-title":"Suboptimal CPAP adherence: half a loaf is better than no bread at all","volume":"55","author":"Billings","year":"2020","journal-title":"Eur Respir J"},{"issue":"2","key":"10.1016\/j.jsmc.2024.10.002_bib17","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1513\/pats.200708-119MG","article-title":"Adherence to continuous positive airway pressure therapy: the challenge to effective treatment","volume":"5","author":"Weaver","year":"2008","journal-title":"Proc Am Thorac Soc"},{"issue":"1","key":"10.1016\/j.jsmc.2024.10.002_bib18","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/s40463-016-0156-0","article-title":"Trends in CPAP adherence over twenty years of data collection: a flattened curve","volume":"45","author":"Rotenberg","year":"2016","journal-title":"J\u00a0Otolaryngol Head Neck Surg"},{"issue":"1","key":"10.1016\/j.jsmc.2024.10.002_bib19","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1053\/smrv.2001.0197","article-title":"Improving CPAP use by patients with the sleep apnoea\/hypopnoea syndrome (SAHS)","volume":"7","author":"Engleman","year":"2003","journal-title":"Sleep Med Rev"},{"issue":"4","key":"10.1016\/j.jsmc.2024.10.002_bib20","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.jsmc.2022.07.002","article-title":"Racial differences in positive airway pressure adherence in the treatment of sleep apnea","volume":"17","author":"May","year":"2022","journal-title":"Sleep Med Clin"},{"issue":"3","key":"10.1016\/j.jsmc.2024.10.002_bib21","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1136\/thoraxjnl-2014-205361","article-title":"Effects of CPAP on body weight in patients with obstructive sleep apnoea: a meta-analysis of randomised trials","volume":"70","author":"Drager","year":"2015","journal-title":"Thorax"},{"key":"10.1016\/j.jsmc.2024.10.002_bib22","series-title":"Long-term health outcomes in obstructive sleep apnea: a systematic review of comparative studies evaluating positive airway pressure and the validity of breathing measures as surrogate outcomes","author":"Balk","year":"2022"},{"issue":"24","key":"10.1016\/j.jsmc.2024.10.002_bib23","doi-asserted-by":"crossref","first-page":"2265","DOI":"10.1056\/NEJMoa1306187","article-title":"CPAP, weight loss, or both for obstructive sleep apnea","volume":"370","author":"Chirinos","year":"2014","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jsmc.2024.10.002_bib24","doi-asserted-by":"crossref","first-page":"105015","DOI":"10.1016\/j.ebiom.2024.105015","article-title":"CPAP may promote an endothelial inflammatory milieu in sleep apnoea after coronary revascularization","volume":"101","author":"Peker","year":"2024","journal-title":"EBioMedicine"},{"issue":"Spec 2","key":"10.1016\/j.jsmc.2024.10.002_bib25","first-page":"398","article-title":"Mandibular advancement devices in obstructive sleep apnea: an updated review","volume":"15","author":"Manetta","year":"2022","journal-title":"Sleep Sci"},{"issue":"12","key":"10.1016\/j.jsmc.2024.10.002_bib26","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1037\/hea0000379","article-title":"Obstructive sleep apnea and weight loss treatment outcome among adults with metabolic syndrome","volume":"35","author":"Whited","year":"2016","journal-title":"Health Psychol"},{"key":"10.1016\/j.jsmc.2024.10.002_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.jacc.2024.06.008","article-title":"Adverse cardiovascular outcomes in patients with obstructive sleep apnea and obesity: metabolic surgery vs usual care","author":"Aminian","year":"2024","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"162","key":"10.1016\/j.jsmc.2024.10.002_bib28","doi-asserted-by":"crossref","DOI":"10.1183\/16000617.0200-2021","article-title":"European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea","volume":"30","author":"Randerath","year":"2021","journal-title":"Eur Respir Rev"},{"key":"10.1016\/j.jsmc.2024.10.002_bib29","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.sleep.2023.10.004","article-title":"Endorsement of \"European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea\" by World Sleep Society","volume":"113","author":"Jacobowitz","year":"2024","journal-title":"Sleep Med"},{"issue":"4","key":"10.1016\/j.jsmc.2024.10.002_bib30","doi-asserted-by":"crossref","first-page":"567","DOI":"10.34197\/ats-scholar.2023-0022OT","article-title":"Obstructive sleep apnea: pathophysiology and endotypes","volume":"4","author":"Sanchez-Azofra","year":"2023","journal-title":"ATS Sch"},{"issue":"4","key":"10.1016\/j.jsmc.2024.10.002_bib31","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1513\/AnnalsATS.202001-064OC","article-title":"A\u00a0novel model to estimate key obstructive sleep apnea endotypes from standard polysomnography and clinical data and their contribution to obstructive sleep apnea severity","volume":"18","author":"Dutta","year":"2021","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.jsmc.2024.10.002_bib32","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.smrv.2016.12.003","article-title":"Phenotypic approaches to obstructive sleep apnoea \u2013 new pathways for targeted therapy","volume":"37","author":"Eckert","year":"2018","journal-title":"Sleep Med Rev"},{"issue":"6","key":"10.1016\/j.jsmc.2024.10.002_bib33","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1164\/rccm.201901-0014TR","article-title":"More than the sum of the respiratory events: personalized medicine approaches for obstructive sleep apnea","volume":"200","author":"Edwards","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"issue":"4","key":"10.1016\/j.jsmc.2024.10.002_bib34","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsad019","article-title":"The scent of love is in the air(way): a potential drug target for sleep apnea?","volume":"46","author":"Osman","year":"2023","journal-title":"Sleep"},{"issue":"5","key":"10.1016\/j.jsmc.2024.10.002_bib35","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1172\/JCI115751","article-title":"Waking genioglossal electromyogram in sleep apnea patients versus normal controls (a neuromuscular compensatory mechanism)","volume":"89","author":"Mezzanotte","year":"1992","journal-title":"J\u00a0Clin Invest"},{"issue":"8","key":"10.1016\/j.jsmc.2024.10.002_bib36","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1164\/rccm.201303-0448OC","article-title":"Defining phenotypic causes of obstructive sleep apnea. Identification of novel therapeutic targets","volume":"188","author":"Eckert","year":"2013","journal-title":"Am J Respir Crit Care Med"},{"issue":"11","key":"10.1016\/j.jsmc.2024.10.002_bib37","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1164\/rccm.201404-0718OC","article-title":"Clinical predictors of the respiratory arousal threshold in patients with obstructive sleep apnea","volume":"190","author":"Edwards","year":"2014","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"10.1016\/j.jsmc.2024.10.002_bib38","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1164\/rccm.200307-1023OC","article-title":"Role of arousals in the pathogenesis of obstructive sleep apnea","volume":"169","author":"Younes","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"10.1016\/j.jsmc.2024.10.002_bib39","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1007\/s11325-022-02665-4","article-title":"Low arousal threshold: a common pathophysiological trait in patients with obstructive sleep apnea syndrome and asthma","volume":"27","author":"Antonaglia","year":"2023","journal-title":"Sleep Breath"},{"key":"10.1016\/j.jsmc.2024.10.002_bib40","doi-asserted-by":"crossref","first-page":"896","DOI":"10.3389\/fneur.2018.00896","article-title":"Inherent vs. Induced loop gain abnormalities in obstructive sleep apnea","volume":"9","author":"Deacon-Diaz","year":"2018","journal-title":"Front Neurol"},{"issue":"7","key":"10.1016\/j.jsmc.2024.10.002_bib41","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.5665\/sleep.3844","article-title":"Obstructive sleep apnea in older adults is a distinctly different physiological phenotype","volume":"37","author":"Edwards","year":"2014","journal-title":"Sleep"},{"issue":"6","key":"10.1016\/j.jsmc.2024.10.002_bib42","article-title":"Menopause is associated with obstructive sleep apnea in a population-based sample from mecklenburg-western pomerania, Germany","volume":"12","author":"Kr\u00fcger","year":"2023","journal-title":"J\u00a0Clin Med"},{"key":"10.1016\/j.jsmc.2024.10.002_bib43","first-page":"zsae185","article-title":"Sex-specific age-related worsening of pathological endotypic traits in patients with obstructive sleep apnea","author":"Hang","year":"2024","journal-title":"Sleep"},{"issue":"5","key":"10.1016\/j.jsmc.2024.10.002_bib44","doi-asserted-by":"crossref","first-page":"809","DOI":"10.5664\/jcsm.7112","article-title":"Prevalence, associated clinical features, and impact on continuous positive airway pressure use of a low respiratory arousal threshold among male United States veterans with obstructive sleep apnea","volume":"14","author":"Zinchuk","year":"2018","journal-title":"J\u00a0Clin Sleep Med"},{"issue":"3","key":"10.1016\/j.jsmc.2024.10.002_bib45","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.jsmc.2019.05.005","article-title":"Precision medicine for obstructive sleep apnea","volume":"14","author":"Light","year":"2019","journal-title":"Sleep Med Clin"},{"issue":"1","key":"10.1016\/j.jsmc.2024.10.002_bib46","doi-asserted-by":"crossref","first-page":"135","DOI":"10.5664\/jcsm.10832","article-title":"Long-term health outcomes for patients with obstructive sleep apnea: placing the Agency for Healthcare Research and Quality report in context-a multisociety commentary","volume":"20","author":"Patil","year":"2024","journal-title":"J\u00a0Clin Sleep Med"},{"issue":"12","key":"10.1016\/j.jsmc.2024.10.002_bib47","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1136\/thoraxjnl-2020-214544","article-title":"Night-to-night variability of respiratory events in obstructive sleep apnoea: a systematic review and meta-analysis","volume":"75","author":"Roeder","year":"2020","journal-title":"Thorax"},{"issue":"6","key":"10.1016\/j.jsmc.2024.10.002_bib48","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1183\/09031936.00032314","article-title":"The different clinical faces of obstructive sleep apnoea: a cluster analysis","volume":"44","author":"Ye","year":"2014","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jsmc.2024.10.002_bib49","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.smrv.2016.10.002","article-title":"Phenotypes in obstructive sleep apnea: a definition, examples and evolution of approaches","volume":"35","author":"Zinchuk","year":"2017","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.jsmc.2024.10.002_bib50","doi-asserted-by":"crossref","first-page":"101519","DOI":"10.1016\/j.smrv.2021.101519","article-title":"Bi-directional relationships between comorbid insomnia and sleep apnea (COMISA)","volume":"60","author":"Sweetman","year":"2021","journal-title":"Sleep Med Rev"},{"issue":"1","key":"10.1016\/j.jsmc.2024.10.002_bib51","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.chest.2022.08.2235","article-title":"POINT:: are OSA phenotypes clinically useful? Yes","volume":"163","author":"Edwards","year":"2023","journal-title":"Chest"},{"issue":"4","key":"10.1016\/j.jsmc.2024.10.002_bib52","article-title":"Obstructive sleep apnea and obesity: implications for public health","volume":"1","author":"Jehan","year":"2017","journal-title":"Sleep Med Disord"},{"issue":"5","key":"10.1016\/j.jsmc.2024.10.002_bib53","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1513\/AnnalsATS.202006-696FR","article-title":"Excessive daytime sleepiness in obstructive sleep apnea. Mechanisms and clinical management","volume":"18","author":"Lal","year":"2021","journal-title":"Ann Am Thorac Soc"},{"issue":"5","key":"10.1016\/j.jsmc.2024.10.002_bib54","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1136\/thoraxjnl-2017-210431","article-title":"Polysomnographic phenotypes and their cardiovascular implications in obstructive sleep apnoea","volume":"73","author":"Zinchuk","year":"2018","journal-title":"Thorax"},{"key":"10.1016\/j.jsmc.2024.10.002_bib55","doi-asserted-by":"crossref","DOI":"10.1177\/14799731241251827","article-title":"Asthma and obstructive sleep apnea: unveiling correlations and treatable traits for comprehensive care","volume":"21","author":"Pardo-Manrique","year":"2024","journal-title":"Chron Respir Dis"},{"issue":"7","key":"10.1016\/j.jsmc.2024.10.002_bib56","doi-asserted-by":"crossref","first-page":"331","DOI":"10.5694\/mja2.51464","article-title":"Treatable traits in asthma: moving beyond diagnostic labels","volume":"216","author":"McDonald","year":"2022","journal-title":"Med J Aust"},{"issue":"1","key":"10.1016\/j.jsmc.2024.10.002_bib57","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1111\/resp.14644","article-title":"Treatable traits models of care","volume":"29","author":"McDonald","year":"2024","journal-title":"Respirology"},{"issue":"12","key":"10.1016\/j.jsmc.2024.10.002_bib58","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1164\/rccm.202310-1778ED","article-title":"Pharmacologic therapy for obstructive sleep apnea: are we seeing some light at the end of the tunnel?","volume":"208","author":"Ayas","year":"2023","journal-title":"Am J Respir Crit Care Med"},{"issue":"7","key":"10.1016\/j.jsmc.2024.10.002_bib59","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1136\/thoraxjnl-2012-202646","article-title":"Multidimensional assessment and tailored interventions for COPD: respiratory utopia or common sense?","volume":"68","author":"McDonald","year":"2013","journal-title":"Thorax"},{"issue":"6","key":"10.1016\/j.jsmc.2024.10.002_bib60","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1097\/MCP.0000000000000324","article-title":"Residual excessive sleepiness in patients with obstructive sleep apnea on treatment with continuous positive airway pressure","volume":"22","author":"Dongol","year":"2016","journal-title":"Curr Opin Pulm Med"},{"issue":"3","key":"10.1016\/j.jsmc.2024.10.002_bib119","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.jsmc.2022.06.010","article-title":"Turning over a new leaf-pharmacologic therapy in obstructive sleep apnea","volume":"17","author":"Hedner","year":"2022","journal-title":"Sleep Med Clin"},{"issue":"6","key":"10.1016\/j.jsmc.2024.10.002_bib62","doi-asserted-by":"crossref","first-page":"2821","DOI":"10.1007\/s12325-021-01710-0","article-title":"Weight loss and maintenance related to the mechanism of action of glucagon-like peptide 1 receptor agonists","volume":"38","author":"Ard","year":"2021","journal-title":"Adv Ther"},{"issue":"8","key":"10.1016\/j.jsmc.2024.10.002_bib63","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1038\/ijo.2016.52","article-title":"Effect of liraglutide 3.0 mg in individuals with obesity and moderate or severe obstructive sleep apnea: the SCALE Sleep Apnea randomized clinical trial","volume":"40","author":"Blackman","year":"2016","journal-title":"Int J Obes (Lond)"},{"key":"10.1016\/j.jsmc.2024.10.002_bib64","doi-asserted-by":"crossref","DOI":"10.1056\/NEJMoa2404881","article-title":"Tirzepatide for the treatment of obstructive sleep apnea and obesity","author":"Malhotra","year":"2024","journal-title":"N\u00a0Engl J Med"},{"issue":"6","key":"10.1016\/j.jsmc.2024.10.002_bib65","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1056\/NEJMoa2301972","article-title":"Triple\u2013hormone-receptor agonist retatrutide for obesity \u2014 a phase 2 trial","volume":"389","author":"Jastreboff Ania","year":"2023","journal-title":"N\u00a0Engl J Med"},{"issue":"11","key":"10.1016\/j.jsmc.2024.10.002_bib66","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1056\/NEJMoa2032183","article-title":"Once-weekly semaglutide in adults with overweight or obesity","volume":"384","author":"Wilding","year":"2021","journal-title":"N\u00a0Engl J Med"},{"issue":"11","key":"10.1016\/j.jsmc.2024.10.002_bib67","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.5665\/sleep.2204","article-title":"A\u00a0randomized, double-blind, placebo-controlled study of an oral, extended-release formulation of phentermine\/topiramate for the treatment of obstructive sleep apnea in obese adults","volume":"35","author":"Winslow","year":"2012","journal-title":"Sleep"},{"issue":"4","key":"10.1016\/j.jsmc.2024.10.002_bib68","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1183\/09031936.00142312","article-title":"The effect of nasal tramazoline with dexamethasone in obstructive sleep apnoea patients","volume":"42","author":"Koutsourelakis","year":"2013","journal-title":"Eur Respir J"},{"issue":"10","key":"10.1016\/j.jsmc.2024.10.002_bib69","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1164\/rccm.200211-1344OC","article-title":"Reduction of sleep-disordered breathing after physostigmine","volume":"168","author":"Hedner","year":"2003","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"10.1016\/j.jsmc.2024.10.002_bib70","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.sleep.2011.09.014","article-title":"Beneficial effect of donepezil on obstructive sleep apnea: a double-blind, placebo-controlled clinical trial","volume":"13","author":"Sukys-Claudino","year":"2012","journal-title":"Sleep Med"},{"issue":"5","key":"10.1016\/j.jsmc.2024.10.002_bib71","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1183\/13993003.00823-2016","article-title":"Desipramine improves upper airway collapsibility and reduces OSA severity in patients with minimal muscle compensation","volume":"48","author":"Taranto-Montemurro","year":"2016","journal-title":"Eur Respir J"},{"issue":"12","key":"10.1016\/j.jsmc.2024.10.002_bib72","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1164\/rccm.202306-1036OC","article-title":"The combination of aroxybutynin and atomoxetine in the treatment of obstructive sleep apnea (MARIPOSA): a randomized controlled trial","volume":"208","author":"Schweitzer","year":"2023","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"10.1016\/j.jsmc.2024.10.002_bib73","doi-asserted-by":"crossref","first-page":"zsx184","DOI":"10.1093\/sleep\/zsx184","article-title":"Pharmacotherapy of apnea by cannabimimetic enhancement, the PACE clinical trial: effects of dronabinol in obstructive sleep apnea","volume":"41","author":"Carley","year":"2018","journal-title":"Sleep"},{"issue":"7","key":"10.1016\/j.jsmc.2024.10.002_bib74","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1093\/sleep\/33.7.982","article-title":"Prospective trial of efficacy and safety of ondansetron and fluoxetine in patients with obstructive sleep apnea syndrome","volume":"33","author":"Prasad","year":"2010","journal-title":"Sleep"},{"issue":"3","key":"10.1016\/j.jsmc.2024.10.002_bib75","doi-asserted-by":"crossref","first-page":"H715","DOI":"10.1152\/ajpheart.00541.2023","article-title":"A\u00a0novel TASK channel antagonist nasal spray reduces sleep apnea severity in physiological responders: a randomized, blinded, trial","volume":"326","author":"Osman","year":"2024","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"6","key":"10.1016\/j.jsmc.2024.10.002_bib76","doi-asserted-by":"crossref","first-page":"e12853","DOI":"10.1111\/jsr.12853","article-title":"The effects of zolpidem in obstructive sleep apnea \u2013 an open-label pilot study","volume":"28","author":"Carberry","year":"2019","journal-title":"J\u00a0Sleep Res"},{"issue":"11","key":"10.1016\/j.jsmc.2024.10.002_bib77","doi-asserted-by":"crossref","first-page":"1973","DOI":"10.5665\/sleep.6226","article-title":"The combination of supplemental oxygen and a hypnotic markedly improves obstructive sleep apnea in patients with a mild to moderate upper airway collapsibility","volume":"39","author":"Edwards","year":"2016","journal-title":"Sleep"},{"issue":"3","key":"10.1016\/j.jsmc.2024.10.002_bib78","doi-asserted-by":"crossref","first-page":"309","DOI":"10.5664\/jcsm.6968","article-title":"Acetazolamide reduces blood pressure and sleep-disordered breathing in patients with hypertension and obstructive sleep apnea: a randomized controlled trial","volume":"14","author":"Eskandari","year":"2018","journal-title":"J\u00a0Clin Sleep Med"},{"issue":"1","key":"10.1016\/j.jsmc.2024.10.002_bib79","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1183\/09031936.00158413","article-title":"Zonisamide reduces obstructive sleep apnoea: a randomised placebo-controlled study","volume":"44","author":"Eskandari","year":"2014","journal-title":"Eur Respir J"},{"issue":"12","key":"10.1016\/j.jsmc.2024.10.002_bib80","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1164\/rccm.202109-2043OC","article-title":"A\u00a0randomized controlled clinical trial exploring safety and tolerability of sulthiame in sleep apnea","volume":"205","author":"Hedner","year":"2022","journal-title":"Am J Respir Crit Care Med"},{"issue":"12","key":"10.1016\/j.jsmc.2024.10.002_bib120","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.5664\/jcsm.11272","article-title":"Gefapixant as a P2X3 receptor antagonist treatment for obstructive sleep apnea: a randomized controlled trial","volume":"20","author":"Robbins","year":"2024","journal-title":"J Clin Sleep Med"},{"issue":"14","key":"10.1016\/j.jsmc.2024.10.002_bib61","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1001\/jama.2020.3514","article-title":"Diagnosis and management of obstructive sleep apnea: a review","volume":"323","author":"Gottlieb","year":"2020","journal-title":"JAMA"},{"issue":"8","key":"10.1016\/j.jsmc.2024.10.002_bib81","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1080\/14656566.2024.2365329","article-title":"Tackling obstructive sleep apnea with pharmacotherapeutics: expert guidance","volume":"25","author":"Harding","year":"2024","journal-title":"Expert Opin Pharmacother"},{"issue":"6","key":"10.1016\/j.jsmc.2024.10.002_bib82","article-title":"New pharmacologic agents for obstructive sleep apnoea: what do we know and what can we expect?","volume":"28","author":"Hedner","year":"2022","journal-title":"Curr Opin Pulm Med"},{"issue":"4","key":"10.1016\/j.jsmc.2024.10.002_bib83","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1152\/japplphysiol.00587.2005","article-title":"Excess weight and sleep-disordered breathing","volume":"99","author":"Young","year":"2005","journal-title":"J\u00a0Appl Physiol (1985)"},{"issue":"1","key":"10.1016\/j.jsmc.2024.10.002_bib84","article-title":"The impact of glucagon-like peptide 1 receptor agonists on obstructive sleep apnoea: a scoping review","volume":"12","author":"Le","year":"2024","journal-title":"Pharmacy (Basel)"},{"issue":"7","key":"10.1016\/j.jsmc.2024.10.002_bib85","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S2213-2600(23)00469-1","article-title":"Continuous positive airway pressure is here to stay","volume":"12","author":"Malhotra","year":"2024","journal-title":"Lancet Respir Med"},{"issue":"8","key":"10.1016\/j.jsmc.2024.10.002_bib86","doi-asserted-by":"crossref","DOI":"10.3390\/life14080963","article-title":"Acetazolamide as an add-on therapy following barbed reposition pharyngoplasty in obstructive sleep apnea: a randomized controlled trial","volume":"14","author":"Hellemans","year":"2024","journal-title":"Life"},{"issue":"8","key":"10.1016\/j.jsmc.2024.10.002_bib87","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsab077","article-title":"The effect of non-benzodiazepine sedative hypnotics on CPAP adherence in patients with OSA: a systematic review and meta-analysis","volume":"44","author":"Wang","year":"2021","journal-title":"Sleep"},{"issue":"11","key":"10.1016\/j.jsmc.2024.10.002_bib88","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1164\/rccm.201806-1100OC","article-title":"Solriamfetol for excessive sleepiness in obstructive sleep apnea (TONES 3). A randomized controlled trial","volume":"199","author":"Schweitzer","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"10.1016\/j.jsmc.2024.10.002_bib89","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/j.chest.2023.11.017","article-title":"Long-term efficacy and safety of pitolisant for residual sleepiness due to OSA","volume":"165","author":"P\u00e9pin","year":"2024","journal-title":"Chest"},{"issue":"9","key":"10.1016\/j.jsmc.2024.10.002_bib90","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1164\/ajrccm.164.9.2103032","article-title":"Modafinil as adjunct therapy for daytime sleepiness in obstructive sleep apnea","volume":"164","author":"Pack","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"10.1016\/j.jsmc.2024.10.002_bib91","doi-asserted-by":"crossref","first-page":"32","DOI":"10.4088\/JCP.09m05536gry","article-title":"A\u00a0double-blind, placebo-controlled study of armodafinil for excessive sleepiness in patients with treated obstructive sleep apnea and comorbid depression","volume":"71","author":"Krystal","year":"2010","journal-title":"J\u00a0Clin Psychiatry"},{"key":"10.1016\/j.jsmc.2024.10.002_bib122","author":"Van Dongen","year":"2024","journal-title":"Chest"},{"key":"10.1016\/j.jsmc.2024.10.002_bib92","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.sleep.2023.05.001","article-title":"Safety and pharmacodynamics of a single infusion of danavorexton in adults with obstructive sleep apnea experiencing excessive daytime sleepiness despite adequate use of CPAP","volume":"107","author":"Bogan","year":"2023","journal-title":"Sleep Med"},{"issue":"5","key":"10.1016\/j.jsmc.2024.10.002_bib93","first-page":"756","article-title":"Obstructive sleep apnea as a cardiovascular risk factor-beyond CPAP","volume":"37","author":"Bock","year":"2021","journal-title":"Can J Cardiol"},{"issue":"7","key":"10.1016\/j.jsmc.2024.10.002_bib94","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1513\/AnnalsATS.202209-761OC","article-title":"Statins restore endothelial protection against complement activity in obstructive sleep apnea: a randomized clinical trial","volume":"20","author":"Shah","year":"2023","journal-title":"Ann Am Thorac Soc"},{"issue":"2","key":"10.1016\/j.jsmc.2024.10.002_bib95","doi-asserted-by":"crossref","first-page":"301","DOI":"10.5664\/jcsm.7638","article-title":"Treatment of adult obstructive sleep apnea with positive airway pressure: an American Academy of sleep medicine systematic review, meta-analysis, and GRADE assessment","volume":"15","author":"Patil","year":"2019","journal-title":"J\u00a0Clin Sleep Med"},{"issue":"7","key":"10.1016\/j.jsmc.2024.10.002_bib96","doi-asserted-by":"crossref","first-page":"e038856","DOI":"10.1136\/bmjopen-2020-038856","volume":"10","author":"Sprung","year":"2020","journal-title":"BMJ Open"},{"issue":"7","key":"10.1016\/j.jsmc.2024.10.002_bib97","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/S2213-2600(24)00144-9","article-title":"Re-evaluating the role of CPAP in OSA management amid obesity pharmacology advancements","volume":"12","author":"Shah","year":"2024","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.jsmc.2024.10.002_bib121","doi-asserted-by":"crossref","first-page":"102633","DOI":"10.1016\/j.eclinm.2024.102633","article-title":"Effect of timed dosing of usual antihypertensives according to patient chronotype on cardiovascular outcomes: the Chronotype sub-study cohort of the Treatment in Morning versus Evening (TIME) study","volume":"72","author":"Pigazzani","year":"2024","journal-title":"EClinicalMedicine"},{"issue":"48","key":"10.1016\/j.jsmc.2024.10.002_bib98","doi-asserted-by":"crossref","first-page":"4565","DOI":"10.1093\/eurheartj\/ehz754","article-title":"Bedtime hypertension treatment improves cardiovascular risk reduction: the Hygia Chronotherapy Trial","volume":"41","author":"Hermida","year":"2020","journal-title":"Eur Heart J"},{"issue":"6","key":"10.1016\/j.jsmc.2024.10.002_bib99","doi-asserted-by":"crossref","first-page":"e11","DOI":"10.1164\/rccm.202101-0190ST","article-title":"Research priorities for patients with heart failure and central sleep apnea. An official American thoracic society research statement","volume":"203","author":"Orr","year":"2021","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jsmc.2024.10.002_bib100","series-title":"Hypoxia: translation in progress","first-page":"275","article-title":"Central sleep apnea at high altitude","author":"Burgess","year":"2016"},{"issue":"1","key":"10.1016\/j.jsmc.2024.10.002_bib101","doi-asserted-by":"crossref","first-page":"38","DOI":"10.5664\/jcsm.27076","article-title":"The current prevalence of sleep disordered breathing in congestive heart failure patients treated with beta-blockers","volume":"4","author":"MacDonald","year":"2008","journal-title":"J\u00a0Clin Sleep Med"},{"issue":"3","key":"10.1016\/j.jsmc.2024.10.002_bib102","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsac113","article-title":"Central sleep apnea: pathophysiologic classification","volume":"46","author":"Javaheri","year":"2023","journal-title":"Sleep"},{"issue":"1","key":"10.1016\/j.jsmc.2024.10.002_bib103","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/resp.12927","article-title":"Pathogenesis of central and complex sleep apnoea","volume":"22","author":"Orr","year":"2017","journal-title":"Respirology"},{"issue":"2","key":"10.1016\/j.jsmc.2024.10.002_bib104","doi-asserted-by":"crossref","first-page":"281","DOI":"10.5665\/sleep.2390","article-title":"Acetazolamide attenuates the ventilatory response to arousal in patients with obstructive sleep apnea","volume":"36","author":"Edwards","year":"2013","journal-title":"Sleep"},{"key":"10.1016\/j.jsmc.2024.10.002_bib105","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.sleep.2023.04.010","article-title":"Acute and long-term effects of acetazolamide in presumed high loop gain sleep apnea","volume":"107","author":"Ni","year":"2023","journal-title":"Sleep Med"},{"issue":"1","key":"10.1016\/j.jsmc.2024.10.002_bib106","doi-asserted-by":"crossref","DOI":"10.1136\/bmjresp-2020-000557","article-title":"Side effects of acetazolamide: a systematic review and meta-analysis assessing overall risk and dose dependence","volume":"7","author":"Schmickl","year":"2020","journal-title":"BMJ Open Respir Res"},{"issue":"4","key":"10.1016\/j.jsmc.2024.10.002_bib107","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1164\/rccm.202104-0846LE","article-title":"Novel drug targets for central apneas in heart failure: on the road","volume":"204","author":"Borrelli","year":"2021","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"10.1016\/j.jsmc.2024.10.002_bib108","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1002\/ejhf.1854","article-title":"Benefit of buspirone on chemoreflex and central apnoeas in heart failure: a randomized controlled crossover trial","volume":"23","author":"Giannoni","year":"2021","journal-title":"Eur J Heart Fail"},{"issue":"8","key":"10.1016\/j.jsmc.2024.10.002_bib109","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1038\/jhh.2009.96","article-title":"Spironolactone reduces severity of obstructive sleep apnoea in patients with resistant hypertension: a preliminary report","volume":"24","author":"Gaddam","year":"2010","journal-title":"J\u00a0Hum Hypertens"},{"key":"10.1016\/j.jsmc.2024.10.002_bib110","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1186\/s12902-015-0074-6","article-title":"An association between liraglutide treatment and reduction in excessive daytime sleepiness in obese subjects with type 2 diabetes","volume":"15","author":"Gomez-Peralta","year":"2015","journal-title":"BMC Endocr Disord"},{"key":"10.1016\/j.jsmc.2024.10.002_bib111","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.sleep.2021.11.015","article-title":"Assessment of the effect of the dual orexin receptor antagonist daridorexant on various indices of disease severity in patients with mild to moderate obstructive sleep apnea","volume":"92","author":"Boof","year":"2022","journal-title":"Sleep Med"},{"issue":"1","key":"10.1016\/j.jsmc.2024.10.002_bib112","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1164\/rccm.202002-0321OC","article-title":"Designer receptors exclusively activated by designer drugs approach to treatment of sleep-disordered breathing","volume":"203","author":"Fleury Curado","year":"2021","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jsmc.2024.10.002_bib113","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.sleep.2023.09.006","article-title":"Perspective: systematic review and meta-analysis in obstructive sleep apnea \u2013 what is lacking?","volume":"111","author":"Lisik","year":"2023","journal-title":"Sleep Med"},{"key":"10.1016\/j.jsmc.2024.10.002_bib114","doi-asserted-by":"crossref","first-page":"101434","DOI":"10.1016\/j.smrv.2021.101434","article-title":"Methodological issues of systematic reviews and meta-analyses in the field of sleep medicine: a meta-epidemiological study","volume":"57","author":"Xu","year":"2021","journal-title":"Sleep Med Rev"},{"issue":"5","key":"10.1016\/j.jsmc.2024.10.002_bib115","doi-asserted-by":"crossref","first-page":"e2413172","DOI":"10.1001\/jamanetworkopen.2024.13172","article-title":"GLP-1 receptor agonist discontinuation among patients with obesity and\/or type 2 diabetes","volume":"7","author":"Do","year":"2024","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.jsmc.2024.10.002_bib116","doi-asserted-by":"crossref","DOI":"10.1001\/jamainternmed.2024.2525","article-title":"Semaglutide vs tirzepatide for weight loss in adults with overweight or obesity","author":"Rodriguez","year":"2024","journal-title":"JAMA Intern Med"},{"issue":"4","key":"10.1016\/j.jsmc.2024.10.002_bib117","doi-asserted-by":"crossref","first-page":"679","DOI":"10.5664\/jcsm.7070","article-title":"Medical cannabis and the treatment of obstructive sleep apnea: an American Academy of sleep medicine position statement","volume":"14","author":"Ramar","year":"2018","journal-title":"J\u00a0Clin Sleep Med"},{"issue":"3","key":"10.1016\/j.jsmc.2024.10.002_bib118","doi-asserted-by":"crossref","DOI":"10.1183\/23120541.00215-2022","article-title":"Multidisciplinary care in chronic airway diseases: the Newcastle model","volume":"8","author":"McDonald","year":"2022","journal-title":"ERJ Open Res"}],"container-title":["Sleep Medicine Clinics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1556407X2400095X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1556407X2400095X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T07:05:58Z","timestamp":1777619158000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1556407X2400095X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":122,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["S1556407X2400095X"],"URL":"https:\/\/doi.org\/10.1016\/j.jsmc.2024.10.002","relation":{},"ISSN":["1556-407X"],"issn-type":[{"value":"1556-407X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Treatable Traits-Based Pharmacologic Treatment of Sleep Apnea","name":"articletitle","label":"Article Title"},{"value":"Sleep Medicine Clinics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jsmc.2024.10.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}