{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T22:23:01Z","timestamp":1789424581045,"version":"build-2803163510"},"reference-count":28,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2004,5,1]],"date-time":"2004-05-01T00:00:00Z","timestamp":1083369600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Research"],"published-print":{"date-parts":[[2004,5]]},"DOI":"10.1016\/j.jss.2003.12.006","type":"journal-article","created":{"date-parts":[[2004,4,15]],"date-time":"2004-04-15T05:36:43Z","timestamp":1082007403000},"page":"32-37","source":"Crossref","is-referenced-by-count":29,"title":["Relative contribution of endogenous opioids to myocardial ischemic tolerance1"],"prefix":"10.1016","volume":"118","author":[{"given":"Matthew A","family":"Romano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth M","family":"Seymour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer A","family":"Berry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert A","family":"McNish","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven F","family":"Bolling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jss.2003.12.006_BIB1","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1111\/j.1471-4159.1989.tb08561.x","article-title":"Presynaptic kappa-opioid receptors on noradrenergic nerve terminals couple to G proteins and interact with the alpha 2-adrenoceptors","volume":"53","author":"Allgaier","year":"1989","journal-title":"J. Neurochem"},{"key":"10.1016\/j.jss.2003.12.006_BIB2","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/0014-2999(84)90565-X","article-title":"Inhibition of the cardiac response to sympathetic nerve stimulation by opioid peptides and its potentiation by morphine and methadone","volume":"102","author":"Ledda","year":"1984","journal-title":"Eur. J. Pharmacol"},{"key":"10.1016\/j.jss.2003.12.006_BIB3","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/0014-2999(85)90013-5","article-title":"Sensitivity to dynorphin-(1\u201313) of the presynaptic inhibitory opiate receptors of the guinea-pig heart","volume":"117","author":"Ledda","year":"1985","journal-title":"Eur. J. Pharmacol"},{"issue":"2","key":"10.1016\/j.jss.2003.12.006_BIB4","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0163-7258(00)00106-6","article-title":"Opioids and cardioprotection","volume":"89","author":"Schultz","year":"2001","journal-title":"Pharmacol. Ther"},{"key":"10.1016\/j.jss.2003.12.006_BIB5","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1139\/o92-090","article-title":"Increased preproenkephalin A gene expression in the rat heart after induction of a myocardial infarction","volume":"70","author":"Paradis","year":"1992","journal-title":"Biochem. Cell. Biol"},{"issue":"Suppl","key":"10.1016\/j.jss.2003.12.006_BIB6","first-page":"II357","article-title":"Opiate drugs and delta-receptor-mediated myocardial protection","volume":"100","author":"Benedict","year":"1999","journal-title":"Circulation"},{"issue":"3","key":"10.1016\/j.jss.2003.12.006_BIB7","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1067\/mtc.2001.116203","article-title":"Opioids confer myocardial tolerance to ischemia","volume":"122","author":"Bolling","year":"2001","journal-title":"J. Thorac. Cardiovasc. Surg"},{"key":"10.1016\/j.jss.2003.12.006_BIB8","article-title":"Differential Effects of Opioid Peptides on Myocardial IschemicTolerance","author":"Romano","year":"2003","journal-title":"J. Surg. Res"},{"key":"10.1016\/j.jss.2003.12.006_BIB9","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1161\/01.CIR.97.13.1282","article-title":"Ischemic preconditioning in the intact rat heart is mediated by delta1- but not mu- or kappa-opioid receptors","volume":"97","author":"Schultz","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.jss.2003.12.006_BIB10","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1067\/mtc.2001.116950","article-title":"Myocardial protection by ischemic preconditioning and delta-opioid receptor activation in the isolated working rat heart","volume":"122","author":"Karck","year":"2001","journal-title":"J. Thorac. Cardiovasc. Surg"},{"key":"10.1016\/j.jss.2003.12.006_BIB11","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1006\/jmcc.1997.0454","article-title":"Ischemic preconditioning and morphine-induced cardioprotection involve the delta (delta)-opioid receptor in the intact rat heart","volume":"29","author":"Schultz","year":"1997","journal-title":"J. Mol. Cell. Cardiol"},{"key":"10.1016\/j.jss.2003.12.006_BIB12","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1161\/01.RES.84.12.1388","article-title":"Cardioprotection of preconditioning by metabolic inhibition in the rat ventricular myocyte. Involvement of kappa-opioid receptor","volume":"84","author":"Wu","year":"1999","journal-title":"Circ. Res"},{"key":"10.1016\/j.jss.2003.12.006_BIB13","doi-asserted-by":"crossref","first-page":"H1953","DOI":"10.1152\/ajpheart.01045.2001","article-title":"Role of delta-opioid receptor agonists on infarct size reduction in swine","volume":"282","author":"Sigg","year":"2002","journal-title":"Am. J. Physiol. Heart Circ. Physiol"},{"key":"10.1016\/j.jss.2003.12.006_BIB14","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1016\/S0735-1097(99)00095-9","article-title":"Effects of naloxone on myocardial ischemic preconditioning in humans","volume":"33","author":"Tomai","year":"1999","journal-title":"J. Am. Coll. Cardiol"},{"key":"10.1016\/j.jss.2003.12.006_BIB15","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1007\/s003950050136","article-title":"Naloxone blockade of myocardial ischemic preconditioning does not require central nervous system participation","volume":"94","author":"Chien","year":"1999","journal-title":"Basic Res. Cardiol"},{"key":"10.1016\/j.jss.2003.12.006_BIB16","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1023\/A:1006856124501","article-title":"Opioid receptor contributes to ischemic preconditioning through protein kinase C activation in rabbits","volume":"186","author":"Miki","year":"1998","journal-title":"Mol. Cell. Biochem"},{"key":"10.1016\/j.jss.2003.12.006_BIB17","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1006\/jmcc.1996.0182","article-title":"Naloxone blockade of myocardial ischemic preconditioning is stereoselective","volume":"28","author":"Chien","year":"1996","journal-title":"J. Mol. Cell. Cardiol"},{"key":"10.1016\/j.jss.2003.12.006_BIB18","first-page":"H2157","article-title":"Evidence for involvement of opioid receptors in ischemic preconditioning in rat hearts","volume":"268","author":"Schultz","year":"1995","journal-title":"Am. J. Physiol"},{"key":"10.1016\/j.jss.2003.12.006_BIB19","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1161\/01.CIR.97.13.1282","article-title":"Ischemic preconditioning in the intact rat heart is mediated by delta1- but not mu- or kappa-opioid receptors","volume":"97","author":"Schultz","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.jss.2003.12.006_BIB20","first-page":"H912","article-title":"Comparison of cardiovascular effects of mu- and delta-opioid receptor antagonists in dogs with congestive heart failure","volume":"267","author":"Imai","year":"1994","journal-title":"Am. J. Physiol"},{"key":"10.1016\/j.jss.2003.12.006_BIB21","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/0735-1097(94)90520-7","article-title":"Short-term effects of naloxone on hemodynamics and baroreflex function in conscious dogs with pacing-induced congestive heart failure","volume":"23","author":"Himura","year":"1994","journal-title":"J. Am. Coll. Cardiol"},{"key":"10.1016\/j.jss.2003.12.006_BIB22","doi-asserted-by":"crossref","first-page":"H1989","DOI":"10.1152\/ajpheart.2000.279.4.H1989","article-title":"Cardiac synthesis, processing, and coronary release of enkephalin-related peptides","volume":"279","author":"Younes","year":"2000","journal-title":"Am. J. Physiol. Heart Circ. Physiol"},{"key":"10.1016\/j.jss.2003.12.006_BIB23","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1007\/BF00501214","article-title":"The sympathetic axons innervating the sinus node of the rabbit possess presynaptic opioid kappa- but not mu- or delta-receptors","volume":"329","author":"Starke","year":"1985","journal-title":"Naunyn Schmiedebergs Arch. Pharmacol"},{"key":"10.1016\/j.jss.2003.12.006_BIB24","first-page":"H153","article-title":"Dynorphin, naloxone, and overflow of norepinephrine during cardiac nerve stimulation in dogs","volume":"263","author":"Gu","year":"1992","journal-title":"Am. J. Physiol. 1992"},{"key":"10.1016\/j.jss.2003.12.006_BIB25","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1016\/S0003-4975(01)03084-3","article-title":"Opioid preconditioning","volume":"72","author":"Sigg","year":"2001","journal-title":"Ann. Thorac. Surg"},{"key":"10.1016\/j.jss.2003.12.006_BIB26","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1093\/oxfordjournals.bja.a013404","article-title":"Fentanyl protects the heart against ischaemic injury via opioid receptors, adenosine A1 receptors and KATP channel linked mechanisms in rats","volume":"84","author":"Kato","year":"2000","journal-title":"Br. J. Anaesth"},{"key":"10.1016\/j.jss.2003.12.006_BIB27","doi-asserted-by":"crossref","first-page":"2296","DOI":"10.1016\/S0735-1097(00)01011-1","article-title":"Delta opioid receptor stimulation mimics ischemic preconditioning in human heart muscle","volume":"36","author":"Bell","year":"2000","journal-title":"J. Am. Coll. Cardiol"},{"key":"10.1016\/j.jss.2003.12.006_BIB28","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/0024-3205(91)90470-V","article-title":"Heterogeneity of immunoreactive dynorphin B-like material in human, rat, rabbit and guinea-pig heart","volume":"48","author":"Spampinato","year":"1991","journal-title":"Life Sci"}],"container-title":["Journal of Surgical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022480403007650?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022480403007650?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,13]],"date-time":"2019-02-13T20:26:09Z","timestamp":1550089569000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022480403007650"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,5]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,5]]}},"alternative-id":["S0022480403007650"],"URL":"https:\/\/doi.org\/10.1016\/j.jss.2003.12.006","relation":{},"ISSN":["0022-4804"],"issn-type":[{"value":"0022-4804","type":"print"}],"subject":[],"published":{"date-parts":[[2004,5]]}}}