{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T05:51:06Z","timestamp":1791179466595,"version":"4.1.0"},"reference-count":23,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2009,11,1]],"date-time":"2009-11-01T00:00:00Z","timestamp":1257033600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Research"],"published-print":{"date-parts":[[2009,11]]},"DOI":"10.1016\/j.jss.2008.10.019","type":"journal-article","created":{"date-parts":[[2008,11,22]],"date-time":"2008-11-22T04:34:11Z","timestamp":1227328451000},"page":"e107-e116","source":"Crossref","is-referenced-by-count":5,"title":["Protective Effect of Adeno-Mediated Human Bcl-xL Gene Transfer to the Mouse Liver in a Partial Ischemia\/Reperfusion Model"],"prefix":"10.1016","volume":"157","author":[{"given":"Kazuo","family":"Honda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taiji","family":"Tohyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Kotegawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoh","family":"Kojima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumiki","family":"Kushihata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jota","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuaki","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jss.2008.10.019_bib1","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1016\/j.gastro.2003.05.005","article-title":"Recent insights on the mechanisms of liver preconditioning","volume":"125","author":"Carini","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jss.2008.10.019_bib2","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/S0039-6060(05)80367-8","article-title":"Protective effect of heat shock pretreatment with heat shock protein induction before hepatic warm ischemic injury caused by Pringle's maneuver","volume":"118","author":"Saad","year":"1995","journal-title":"Surgery"},{"key":"10.1016\/j.jss.2008.10.019_bib3","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1002\/hep.510310221","article-title":"Impact of hyperthermic preconditioning on postischemic hepatic microcirculatory disturbances in an isolated perfusion model of the rat liver","volume":"31","author":"Terajima","year":"2000","journal-title":"Hepatology"},{"issue":"71","key":"10.1016\/j.jss.2008.10.019_bib4","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1097\/00007890-200104150-00007","article-title":"Protective effect of heat preconditioning of rat liver graft resulting in improved transplant survival","volume":"15","author":"Matsumoto","year":"2001","journal-title":"Transplantation"},{"key":"10.1016\/j.jss.2008.10.019_bib5","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1007\/s10620-005-2945-6","article-title":"Downregulation of cytokine release by heat preconditioning of livers used for transplantation in rats","volume":"50","author":"Watanabe","year":"2005","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.jss.2008.10.019_bib6","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1097\/00000658-199908000-00008","article-title":"Reduction of ischemia-reperfusion injury of the liver by in vivo adenovirus-mediated gene transfer of the antiapoptotic Bcl-2 gene","volume":"230","author":"Bilbao","year":"1999","journal-title":"Ann Surg"},{"issue":"67","key":"10.1016\/j.jss.2008.10.019_bib7","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1097\/00007890-199903270-00001","article-title":"Genetic modification of liver grafts with an adenoviral vector encoding the Bcl-2 gene improves organ preservation","volume":"27","author":"Bilbao","year":"1999","journal-title":"Transplantation"},{"key":"10.1016\/j.jss.2008.10.019_bib8","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1006\/jsre.2001.6313","article-title":"Adenovirus mediated gene transfer of antiapoptotic protein in hepatic ischemia-reperfusion injury: the paradoxical effect of Bcl-2 expression in the reperfused liver","volume":"103","author":"Oshiro","year":"2002","journal-title":"J Surg Res"},{"key":"10.1016\/j.jss.2008.10.019_bib9","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1159\/000049686","article-title":"Expression of Bcl-2 family reduces apoptotic hepatocytes after excessive hepatectomy","volume":"33","author":"Kamimukai","year":"2001","journal-title":"Eur Surg Res"},{"key":"10.1016\/j.jss.2008.10.019_bib10","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1053\/jhep.2001.25387","article-title":"Expression and role of Bcl-xL in human hepatocellular carcinomas","volume":"34","author":"Takehara","year":"2001","journal-title":"Hepatology"},{"key":"10.1016\/j.jss.2008.10.019_bib11","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/j.surg.2003.11.015","article-title":"Prognostic significance of Bcl-xL in human hepatocellular carcinoma","volume":"135","author":"Watanabe","year":"2004","journal-title":"Surgery"},{"issue":"80","key":"10.1016\/j.jss.2008.10.019_bib12","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1097\/01.tp.0000178293.65311.8b","article-title":"Adenoviral bcl-2 transfer improves survival and early graft function after ischemia and reperfusion in rat liver transplantation","volume":"27","author":"Rentsh","year":"2005","journal-title":"Transplantation"},{"key":"10.1016\/j.jss.2008.10.019_bib13","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.jss.2005.11.586","article-title":"Expression of anti-apoptotic protein, Bcl-2, in liver regeneration after a partial hepatectomy","volume":"134","author":"Takushi","year":"2006","journal-title":"J Sug Res"},{"key":"10.1016\/j.jss.2008.10.019_bib14","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1038\/sj.gt.3301211","article-title":"Adeno-associated virus vector-mediated bcl-2 gene transfer into post-ischemic gerbil braion in vivo: Prospects for gene therapy of ischemia-induced neuronal death","volume":"7","author":"Simazaki","year":"2000","journal-title":"Gene Ther"},{"key":"10.1016\/j.jss.2008.10.019_bib15","article-title":"Viral gene transfer of the antiapoptotic factor Bcl-2 protects against chronic postischemic heart failure","volume":"24","author":"Chatterjee","year":"2002","journal-title":"Circulation"},{"issue":"79","key":"10.1016\/j.jss.2008.10.019_bib16","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1097\/01.TP.0000153368.08861.15","article-title":"Overexpression of human Bcl-2 in syngenic rat donor lungs preserves posttransplant function and reduces intragraft caspase activity and interleukin-1beta production","volume":"15","author":"Cooke","year":"2005","journal-title":"Transplantation"},{"key":"10.1016\/j.jss.2008.10.019_bib17","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1111\/j.1600-6143.2005.00826.x","article-title":"Adenovirus-mediated bcl-2 gene transfer inhibits renal ischemia\/reperfusion induced tubular oxidative stress and apoptosis","volume":"5","author":"Chiang-Ting","year":"2005","journal-title":"Am J Transplant"},{"issue":"93","key":"10.1016\/j.jss.2008.10.019_bib18","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1002\/jcb.20221","article-title":"Cytoprotection by bcl-2 gene transfer against ischemic liver injuries together with repressed lipid peroxidation and increased ascorbic acid in livers and serum","volume":"15","author":"Yanada","year":"2004","journal-title":"J Cell Biochem"},{"key":"10.1016\/j.jss.2008.10.019_bib19","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1089\/hum.2005.16.627","article-title":"Hemagglutinating virus of Japan-artificial viral envelope liposome-mediated cotransfer of bag-1 and bcl-2 genes protects hepatic cells against ischemic injury through BAG-1-assisted preferential enhancement of bcl-2 protein expression","volume":"16","author":"Yanada","year":"2005","journal-title":"Hum Gene Ther"},{"issue":"311","key":"10.1016\/j.jss.2008.10.019_bib20","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.bbrc.2003.09.160","article-title":"Bcl-xL gene transfer protects the heart against ischemia\/reperfusion injury","volume":"7","author":"Huang","year":"2003","journal-title":"Biochem Bioph Res Co"},{"issue":"112","key":"10.1016\/j.jss.2008.10.019_bib21","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1161\/CIRCULATIONAHA.105.535740","article-title":"Bcl-xL gene transfer inhibits Bax translocation and prolongs cardiac preservation time in rats","volume":"5","author":"Huang","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.jss.2008.10.019_bib22","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1097\/01.tp.0000287334.38933.e3","article-title":"Bcl-xL augmentation potentially reduces ischemia\/reperfusion induced proximal and distal tubular apoptosis and autophagy","volume":"84","author":"Chien","year":"2007","journal-title":"Transplantation"},{"key":"10.1016\/j.jss.2008.10.019_bib23","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1053\/j.gastro.2004.07.019","article-title":"Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses","volume":"127","author":"Takehara","year":"2004","journal-title":"Gastroenterology"}],"container-title":["Journal of Surgical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022480408006719?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022480408006719?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,24]],"date-time":"2018-12-24T01:28:47Z","timestamp":1545614927000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022480408006719"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,11]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,11]]}},"alternative-id":["S0022480408006719"],"URL":"https:\/\/doi.org\/10.1016\/j.jss.2008.10.019","relation":{},"ISSN":["0022-4804"],"issn-type":[{"value":"0022-4804","type":"print"}],"subject":[],"published":{"date-parts":[[2009,11]]}}}