{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T20:37:50Z","timestamp":1761597470547},"reference-count":18,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2014,5,1]],"date-time":"2014-05-01T00:00:00Z","timestamp":1398902400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Research"],"published-print":{"date-parts":[[2014,5]]},"DOI":"10.1016\/j.jss.2013.11.1085","type":"journal-article","created":{"date-parts":[[2013,11,21]],"date-time":"2013-11-21T17:19:01Z","timestamp":1385054341000},"page":"309-315","source":"Crossref","is-referenced-by-count":3,"title":["Impact of single immunosuppressive drug withdrawal on lymphocyte immunoreactivity"],"prefix":"10.1016","volume":"188","author":[{"given":"Meenakshi","family":"Verma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Awdishu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Lane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bayda","family":"Bahur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wint","family":"Lwin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Halvor","family":"McGee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Steiner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"Finn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Perkins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jss.2013.11.1085_bib1","doi-asserted-by":"crossref","first-page":"481","DOI":"10.2215\/CJN.04800908","article-title":"Calcineurin inhibitor nephrotoxicity","volume":"4","author":"Naesens","year":"2009","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.jss.2013.11.1085_bib2","doi-asserted-by":"crossref","first-page":"430","DOI":"10.2215\/CJN.05840710","article-title":"Switching from calcineurin inhibitor-based regimens to a belatacept-based regimen in renal transplant recipients: a randomized phase II study","volume":"6","author":"Rostaing","year":"2011","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.jss.2013.11.1085_bib3","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1097\/FTD.0b013e318237e33c","article-title":"Pharmacodynamic monitoring of cyclosporin a reveals risk of opportunistic infections and malignancies in renal transplant recipients 65 years and older","volume":"33","author":"Sommerer","year":"2011","journal-title":"Ther Drug Monit"},{"key":"10.1016\/j.jss.2013.11.1085_bib4","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1097\/00007890-199502000-00006","article-title":"Incidence, determinants, and consequences of subclinical noncompliance with immunosuppressive therapy in renal transplant recipients","volume":"59","author":"De Geest","year":"1995","journal-title":"Transplantation"},{"key":"10.1016\/j.jss.2013.11.1085_bib5","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1111\/j.1600-6143.2011.03840.x","article-title":"Understanding the causes of kidney transplant failure: the dominant role of antibody-mediated rejection and nonadherence","volume":"12","author":"Sellares","year":"2012","journal-title":"Am J Transplant"},{"key":"10.1016\/j.jss.2013.11.1085_bib6","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1111\/j.1399-3046.2010.01409.x","article-title":"Variability in tacrolimus blood levels increases the risk of late rejection and graft loss after solid organ transplantation in older children","volume":"14","author":"Pollock-Barziv","year":"2010","journal-title":"Pediatr transplant"},{"key":"10.1016\/j.jss.2013.11.1085_bib7","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.healun.2007.05.004","article-title":"Interleukin-17 and airway inflammation: a longitudinal airway biopsy study after lung transplantation","volume":"26","author":"Snell","year":"2007","journal-title":"J Heart Lung Transpl"},{"key":"10.1016\/j.jss.2013.11.1085_bib8","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.immuni.2006.06.002","article-title":"Th17: an effector CD4 T cell lineage with regulatory T cell ties","volume":"24","author":"Weaver","year":"2006","journal-title":"Immunity"},{"key":"10.1016\/j.jss.2013.11.1085_bib9","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1365-2249.2009.04037.x","article-title":"Translational mini-review series on Th17 cells: function and regulation of human T helper 17 cells in health and disease","volume":"159","author":"Crome","year":"2010","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.jss.2013.11.1085_bib10","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/j.1432-2277.2004.00032.x","article-title":"Rapamycin rescue therapy in patients after kidney transplantation: first clinical experience","volume":"18","author":"Weber","year":"2005","journal-title":"Transpl Int"},{"key":"10.1016\/j.jss.2013.11.1085_bib11","doi-asserted-by":"crossref","first-page":"2715","DOI":"10.1056\/NEJMra033540","article-title":"Immunosuppressive drugs for kidney transplantation","volume":"351","author":"Halloran","year":"2004","journal-title":"The New Engl j med"},{"key":"10.1016\/j.jss.2013.11.1085_bib12","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/S0140-6736(98)07493-5","article-title":"Immunosuppressive strategies in transplantation","volume":"353","author":"Denton","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.jss.2013.11.1085_bib13","doi-asserted-by":"crossref","first-page":"4138","DOI":"10.1016\/j.transproceed.2009.08.065","article-title":"Renal function outcomes in kidney transplant recipients after conversion to everolimus-based immunosuppression regimen with CNI reduction or elimination","volume":"41","author":"Cataneo-Davila","year":"2009","journal-title":"Transpl Proc"},{"key":"10.1016\/j.jss.2013.11.1085_bib14","first-page":"548","article-title":"Transplantation: Does switching to a CNI-free regimen reduce cancer risk?","volume":"7","author":"Ireland","year":"2011","journal-title":"Nat Rev Nephrol"},{"key":"10.1016\/j.jss.2013.11.1085_bib15","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.2215\/CJN.07241009","article-title":"Optimizing medication adherence: an ongoing opportunity to improve outcomes after kidney transplantation","volume":"5","author":"Prendergast","year":"2010","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.jss.2013.11.1085_bib16","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/S0041-1345(98)01627-3","article-title":"Odds probabilities of compliance and noncompliance in patients with a functioning renal transplant: a multicenter study","volume":"31","author":"Greenstein","year":"1999","journal-title":"Transpl Proc"},{"key":"10.1016\/j.jss.2013.11.1085_bib17","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1373\/clinchem.2003.024950","article-title":"Sensitivity of whole-blood T lymphocytes in individual patients to tacrolimus (FK\u00a0506):\u00a0impact of interleukin-2 mRNA expression as surrogate measure of immunosuppressive effect","volume":"50","author":"Hartel","year":"2004","journal-title":"Clin chem"},{"key":"10.1016\/j.jss.2013.11.1085_bib18","doi-asserted-by":"crossref","first-page":"3327","DOI":"10.1016\/j.transproceed.2006.10.181","article-title":"Paradoxical response to tacrolimus assessed by interleukin-2 gene expression","volume":"38","author":"El-Safa","year":"2006","journal-title":"Transplant proc"}],"container-title":["Journal of Surgical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022480413021239?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022480413021239?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,3]],"date-time":"2019-08-03T19:08:38Z","timestamp":1564859318000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022480413021239"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,5]]}},"alternative-id":["S0022480413021239"],"URL":"https:\/\/doi.org\/10.1016\/j.jss.2013.11.1085","relation":{},"ISSN":["0022-4804"],"issn-type":[{"value":"0022-4804","type":"print"}],"subject":[],"published":{"date-parts":[[2014,5]]}}}