{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T21:39:08Z","timestamp":1775597948300,"version":"3.50.1"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofsurgicalresearch.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Research"],"published-print":{"date-parts":[[2020,1]]},"DOI":"10.1016\/j.jss.2019.07.092","type":"journal-article","created":{"date-parts":[[2019,8,22]],"date-time":"2019-08-22T05:58:47Z","timestamp":1566453527000},"page":"467-474","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Effect of Hydrogen Sulfide on the Mitogen-Activated Protein Kinase Signaling Pathway in Cultured Skin Macrophages of Burned Rats"],"prefix":"10.1016","volume":"245","author":[{"given":"Yi","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong-Jin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xian-Zhen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xing-Long","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jss.2019.07.092_bib1","first-page":"62","article-title":"Advancement in the research of the role of macrophages in wound healing","volume":"29","author":"Xue","year":"2013","journal-title":"Zhonghua Shao Shang Za Zhi"},{"key":"10.1016\/j.jss.2019.07.092_bib2","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.ijsu.2015.08.016","article-title":"Inhibition of reactive oxygen species downregulates the MAPK pathway in rat spinal cord after limb ischemia reperfusion injury","volume":"22","author":"Choi","year":"2015","journal-title":"Int J Surg"},{"key":"10.1016\/j.jss.2019.07.092_bib3","doi-asserted-by":"crossref","first-page":"2435","DOI":"10.1128\/MCB.19.4.2435","article-title":"Mitogen-activated protein kinases: specific messages from ubiquitous messengers","volume":"19","author":"Schaeffer","year":"1999","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.jss.2019.07.092_bib4","doi-asserted-by":"crossref","first-page":"e0149486","DOI":"10.1371\/journal.pone.0149486","article-title":"SB203580 modulates p38 MAPK signaling and dengue virus-induced liver injury by reducing MAPKAPK2, HSP27, and ATF2 phosphorylation","volume":"11","author":"Sreekanth","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.jss.2019.07.092_bib5","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1093\/cvr\/cvw037","article-title":"Additive cardioprotection by pharmacological postconditioning with hydrogen sulfide and nitric oxide donors in mouse heart: S-sulfhydration vs S-nitrosylation","volume":"110","author":"Sun","year":"2016","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.jss.2019.07.092_bib6","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1042\/CS20150521","article-title":"Cystathionine \u03b2-synthase-derived hydrogen sulfide is involved in human malignant hyperthermia","volume":"130","author":"Vellecco","year":"2016","journal-title":"Clin Sci"},{"key":"10.1016\/j.jss.2019.07.092_bib7","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.niox.2015.09.007","article-title":"Endogenously produced hydrogen sulfide is involved in porcine oocyte maturation in\u00a0vitro","volume":"51","author":"Nevoral","year":"2015","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.jss.2019.07.092_bib8","first-page":"54","article-title":"Influence of hydrogen sulfide on important organs in rat with severe burn","volume":"27","author":"Li","year":"2011","journal-title":"Zhonghua Shao Shang Za Zhi"},{"key":"10.1016\/j.jss.2019.07.092_bib9","first-page":"408","article-title":"Effects of hydrogen sulfide on the secretion of cytokines in macrophages of deep partial-thickness burn wound in rats","volume":"32","author":"Li","year":"2016","journal-title":"Zhonghua Shao Shang Za Zhi"},{"key":"10.1016\/j.jss.2019.07.092_bib10","first-page":"254","article-title":"Effect of hydrogen sulfide on hydrogen sulfide\/cyst thioether - lyase system in burn wound macrophages","volume":"11","author":"Li","year":"2016","journal-title":"Zhonghua Sunshang Yu Xiufu Zazhi"},{"key":"10.1016\/j.jss.2019.07.092_bib11","first-page":"460841","article-title":"Development of animal model for studying deep second-degree thermal burns","volume":"2012","author":"Tavares Pereira Ddos","year":"2012","journal-title":"J Biomed Biotechnol"},{"key":"10.1016\/j.jss.2019.07.092_bib12","doi-asserted-by":"crossref","first-page":"9878109","DOI":"10.1155\/2017\/9878109","article-title":"Design and testing of an experimental steam-induced burn model in rats","volume":"2017","author":"Porumb","year":"2017","journal-title":"Biomed Res Int"},{"key":"10.1016\/j.jss.2019.07.092_bib13","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/S0039-6109(02)00200-1","article-title":"Inflammatory mediators in wound healing","volume":"83","author":"Henry","year":"2003","journal-title":"Surg Clin North Am"},{"key":"10.1016\/j.jss.2019.07.092_bib14","first-page":"329","article-title":"The role of macrophages in the repair of trauma","volume":"38","author":"Wang","year":"2016","journal-title":"Chin J Cel Biol"},{"key":"10.1016\/j.jss.2019.07.092_bib15","first-page":"CR26","article-title":"Soluble cytokine receptors sTNFR I and sTNFR II, receptor antagonist IL-1ra, and anti-inflammatory cytokines IL-10 and IL-13 in the pathogenesis of systemic inflammatory response syndrome in the course of burns in children","volume":"15","author":"Sikora","year":"2009","journal-title":"Med Sci Monit"},{"key":"10.1016\/j.jss.2019.07.092_bib16","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/nrm1104","article-title":"Phagocyte sabotage: disruption of macrophage signaling by bacterial pathogens","volume":"4","author":"Rosenberger","year":"2003","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1016\/j.jss.2019.07.092_bib17","first-page":"643","article-title":"Skin wound healing modulation by macrophages","volume":"3","author":"Mathieu","year":"2010","journal-title":"Int J Clin Exp Pathol"},{"key":"10.1016\/j.jss.2019.07.092_bib18","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1007\/s005950170150","article-title":"The importance of peripheral blood leukocytes and macrophage infiltration on bronchial wall wound healing in rats treated preoperatively with anticancer agents","volume":"31","author":"Shirafuji","year":"2001","journal-title":"Surg Today"},{"key":"10.1016\/j.jss.2019.07.092_bib19","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1126\/science.270.5240.1326","article-title":"Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis","volume":"270","author":"Xia","year":"1995","journal-title":"Science"},{"key":"10.1016\/j.jss.2019.07.092_bib20","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1002\/jnr.10168","article-title":"Involvement of caspase-3 and p38 mitogen-activated protein kinase in cobalt chloride-induced apoptosis in PC12 cell","volume":"67","author":"Zou","year":"2002","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.jss.2019.07.092_bib21","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s11010-011-1137-2","article-title":"Inhibition of ROS-activated ERK1\/2 pathway contributes to the protection of H2S against chemical hypoxia-induced injury in H9C2 cells","volume":"363","author":"Dong","year":"2012","journal-title":"Mol Cell Biochem"},{"key":"10.1016\/j.jss.2019.07.092_bib22","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1111\/bph.12562","article-title":"H2 S modulates duodenal motility in male rats via activating TRPV1 and K ATP, channels","volume":"171","author":"Lu","year":"2014","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.jss.2019.07.092_bib23","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1126\/scisignal.268re2","article-title":"Signaling by gasotransmitters","volume":"2","author":"Mustafa","year":"2009","journal-title":"Sci Signal"},{"key":"10.1016\/j.jss.2019.07.092_bib24","first-page":"95","article-title":"Burn injury: review of pathophysiology and therapeutic modalities in major burns","volume":"30","author":"Kaddoura","year":"2017","journal-title":"Ann Burns Fire Disasters"},{"key":"10.1016\/j.jss.2019.07.092_bib25","first-page":"969618","article-title":"Surgical approaches to create murine models of human wound healing","volume":"2011","author":"Wong","year":"2011","journal-title":"J Biomed Biotechnol"}],"container-title":["Journal of Surgical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022480419305839?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022480419305839?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T14:48:59Z","timestamp":1758379739000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022480419305839"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":25,"alternative-id":["S0022480419305839"],"URL":"https:\/\/doi.org\/10.1016\/j.jss.2019.07.092","relation":{},"ISSN":["0022-4804"],"issn-type":[{"value":"0022-4804","type":"print"}],"subject":[],"published":{"date-parts":[[2020,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of Hydrogen Sulfide on the Mitogen-Activated Protein Kinase Signaling Pathway in Cultured Skin Macrophages of Burned Rats","name":"articletitle","label":"Article Title"},{"value":"Journal of Surgical Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jss.2019.07.092","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}