{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T19:13:24Z","timestamp":1793042004815,"version":"4.5.0"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofsurgicalresearch.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Research"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1016\/j.jss.2020.11.058","type":"journal-article","created":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T23:58:11Z","timestamp":1608681491000},"page":"506-515","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Predictors of Nonsentinel Lymph Node Metastasis in Cutaneous Melanoma: A Systematic Review and Meta-Analysis"],"prefix":"10.1016","volume":"260","author":[{"given":"Arezoo","family":"Rajaee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pooyan","family":"Sadr-Eshkevari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly M.","family":"McMasters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael E.","family":"Egger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jss.2020.11.058_bib1","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1245\/s10434-018-6513-7","article-title":"Melanoma staging: American joint committee on cancer (AJCC) 8th edition and beyond","volume":"25","author":"Gershenwald","year":"2018","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib2","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1002\/jso.20084","article-title":"Lessons learned from the sunbelt melanoma trial","volume":"86","author":"McMasters","year":"2004","journal-title":"J Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib3","first-page":"392","article-title":"Technical details of intraoperative lymphatic mapping for early stage melanoma","volume":"127","author":"Morton","year":"1992","journal-title":"JAMA Surg"},{"key":"10.1016\/j.jss.2020.11.058_bib4","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1200\/JCO.1999.17.3.976","article-title":"Multi-institutional melanoma lymphatic mapping experience: the prognostic value of sentinel lymph node status in 612 stage I or II melanoma patients","volume":"17","author":"Gershenwald","year":"1999","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib5","doi-asserted-by":"crossref","first-page":"3677","DOI":"10.1200\/JCO.2004.01.012","article-title":"Factors predictive of tumor-positive nonsentinel lymph nodes after tumor-positive sentinel lymph node dissection for melanoma","volume":"22","author":"Lee","year":"2004","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib6","doi-asserted-by":"crossref","first-page":"4464","DOI":"10.1200\/JCO.2006.06.3198","article-title":"Sentinel and nonsentinel node status in stage IB and II melanoma patients: two-step prognostic indicators of survival","volume":"24","author":"Cascinelli","year":"2006","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib7","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1056\/NEJMoa1613210","article-title":"Completion dissection or observation for sentinel-node metastasis in melanoma","volume":"376","author":"Faries","year":"2017","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jss.2020.11.058_bib8","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/S1470-2045(16)00141-8","article-title":"Complete lymph node dissection versus no dissection in patients with sentinel lymph node biopsy positive melanoma (DeCOG-SLT): a multicentre, randomised, phase 3 trial","volume":"17","author":"Leiter","year":"2016","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib9","doi-asserted-by":"crossref","first-page":"1824","DOI":"10.1056\/NEJMoa1709030","article-title":"Adjuvant nivolumab versus ipilimumab in resected stage III or IV melanoma","volume":"377","author":"Weber","year":"2017","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jss.2020.11.058_bib10","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1056\/NEJMoa1708539","article-title":"Adjuvant dabrafenib plus trametinib in stage III BRAF-mutated melanoma","volume":"377","author":"Long","year":"2017","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jss.2020.11.058_bib11","doi-asserted-by":"crossref","first-page":"e1000097","DOI":"10.1371\/journal.pmed.1000097","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"6","author":"Moher","year":"2009","journal-title":"PLoS Med"},{"key":"10.1016\/j.jss.2020.11.058_bib12","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.jclinepi.2011.05.008","article-title":"Development of the RTI item bank on risk of bias and precision of observational studies","volume":"65","author":"Viswanathan","year":"2012","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.jss.2020.11.058_bib13","doi-asserted-by":"crossref","DOI":"10.1245\/s10434-018-6647-7","article-title":"Prediction of residual nodal disease at completion dissection following positive sentinel lymph node biopsy for melanoma","author":"Sinnamon","year":"2018","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib14","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1016\/j.amjsurg.2018.01.033","article-title":"Patients with sentinel lymph node positive melanoma: who needs completion lymph node dissection?","volume":"215","author":"Schuitevoerder","year":"2018","journal-title":"Am J Surg"},{"key":"10.1016\/j.jss.2020.11.058_bib15","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1111\/1346-8138.14577","article-title":"Complete lymph node dissection or observation in melanoma patients with multiple positive sentinel lymph nodes: a single-center retrospective analysis","volume":"45","author":"Persa","year":"2018","journal-title":"J Dermatol"},{"key":"10.1016\/j.jss.2020.11.058_bib16","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1016\/j.ejso.2017.07.006","article-title":"A prediction tool incorporating the biomarker S-100B for patient selection for completion lymph node dissection in stage III melanoma","volume":"43","author":"Damude","year":"2017","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib17","first-page":"S128","article-title":"The additional value of S-100B in a risk stratifying model for the prediction of non-sentinel node positivity in melanoma patients","volume":"23","author":"Damude","year":"2016","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib18","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1007\/s10585-017-9854-x","article-title":"Is the non-sentinel lymph node compartment the next site for melanoma progression from the sentinel lymph node compartment in the regional nodal basin?","volume":"34","author":"Rios-Cantu","year":"2017","journal-title":"Clin Exp Metastasis"},{"key":"10.1016\/j.jss.2020.11.058_bib19","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1097\/DAD.0000000000000488","article-title":"Increased angiogenesis and lymphangiogenesis in metastatic sentinel lymph nodes is associated with nonsentinel lymph node involvement and distant metastasis in patients with melanoma","volume":"38","author":"Pastushenko","year":"2016","journal-title":"Am J Dermatopathol"},{"key":"10.1016\/j.jss.2020.11.058_bib20","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.amjsurg.2015.05.016","article-title":"Predictive factors for sentinel lymph nodes and non-sentinel lymph nodes metastatic involvement: a database study of 1,041 melanoma patients","volume":"211","author":"Kibrite","year":"2016","journal-title":"Am J Surg"},{"key":"10.1016\/j.jss.2020.11.058_bib21","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1177\/0194599815605494","article-title":"Completion lymph node dissection based on risk of nonsentinel metastasis in cutaneous melanoma of the head and neck","volume":"154","author":"Fritsch","year":"2016","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.jss.2020.11.058_bib22","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1097\/CMR.0000000000000202","article-title":"Metastatic area ratio can help predict nonsentinel node positivity in melanoma patients","volume":"26","author":"Bertolli","year":"2016","journal-title":"Melanoma Res"},{"key":"10.1016\/j.jss.2020.11.058_bib23","first-page":"301","article-title":"Prognostic significance of microscopic tumor burden in sentinel lymph node in patients with cutaneous melanoma","volume":"35","author":"Kim","year":"2015","journal-title":"Anticancer Res"},{"key":"10.1016\/j.jss.2020.11.058_bib24","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1200\/JCO.2013.50.7681","article-title":"Nonsentinel lymph node status in patients with cutaneous melanoma: results from a multi-institution prognostic study","volume":"32","author":"Pasquali","year":"2014","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib25","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.ejso.2013.08.022","article-title":"Accuracy of the non-sentinel node risk score (N-SNORE) in patients with cutaneous melanoma and positive sentinel lymph nodes: a retrospective study","volume":"40","author":"Feldmann","year":"2014","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib26","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1097\/CCO.0b013e32835dafb4","article-title":"Completion lymph node dissection after a positive sentinel node: no longer a must?","volume":"25","author":"van der Ploeg","year":"2013","journal-title":"Curr Opin Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib27","doi-asserted-by":"crossref","first-page":"2206","DOI":"10.1200\/JCO.2010.31.6760","article-title":"Prognosis in patients with sentinel node-positive melanoma is accurately defined by the combined Rotterdam tumor load and Dewar topography criteria","volume":"29","author":"van der Ploeg","year":"2011","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib28","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.ejso.2012.10.014","article-title":"Assessment of a new scoring system for predicting non-sentinel node positivity in sentinel node-positive melanoma patients","volume":"39","author":"Wevers","year":"2013","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib29","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1001\/jamasurg.2013.3044","article-title":"Staging of regional lymph nodes in melanoma: a case for including nonsentinel lymph node positivity in the American Joint Committee on Cancer staging system","volume":"148","author":"Leung","year":"2013","journal-title":"JAMA Surg"},{"key":"10.1016\/j.jss.2020.11.058_bib30","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/1756-9966-32-47","article-title":"SLN melanoma micrometastasis predictivity of nodal status: a long term retrospective study","volume":"32","author":"Migliano","year":"2013","journal-title":"J Exp Clin Cancer Res"},{"key":"10.1016\/j.jss.2020.11.058_bib31","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1245\/s10434-012-2652-4","article-title":"Evidence for a better nodal staging system for melanoma: the clinical relevance of metastatic disease confined to the sentinel lymph nodes","volume":"20","author":"Reintgen","year":"2013","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib32","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1111\/j.1346-8138.2011.01318.x","article-title":"Prediction of additional lymph node positivity and clinical outcome of micrometastases in sentinel lymph nodes in cutaneous melanoma: a multi-institutional study of 450 patients in Japan","volume":"39","author":"Namikawa","year":"2012","journal-title":"J Dermatol"},{"key":"10.1016\/j.jss.2020.11.058_bib33","doi-asserted-by":"crossref","first-page":"3309","DOI":"10.1245\/s10434-011-1750-z","article-title":"Inguinopelvic lymphadenectomy following positive inguinal sentinel lymph node biopsy in melanoma: true frequency of synchronous pelvic metastases","volume":"18","author":"Chu","year":"2011","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib34","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1097\/DAD.0b013e3182042893","article-title":"Identification of nodal metastases in melanoma using sox-10","volume":"33","author":"Jennings","year":"2011","journal-title":"Am J Dermatopathol"},{"key":"10.1016\/j.jss.2020.11.058_bib35","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.jaad.2010.02.047","article-title":"Analysis of predictive factors for the outcome of complete lymph node dissection in melanoma patients with metastatic sentinel lymph nodes","volume":"64","author":"Kunte","year":"2011","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jss.2020.11.058_bib36","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1111\/j.1365-2559.2011.03931.x","article-title":"No non-sentinel node involvement in melanoma patients with limited Breslow thickness and low sentinel node tumour load","volume":"59","author":"Bogenrieder","year":"2011","journal-title":"Histopathology"},{"key":"10.1016\/j.jss.2020.11.058_bib37","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.jamcollsurg.2013.12.014","article-title":"Comparison of sentinel lymph node micrometastatic tumor burden measurements in melanoma","volume":"218","author":"Egger","year":"2014","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.jss.2020.11.058_bib38","doi-asserted-by":"crossref","first-page":"S13","DOI":"10.1245\/s10434-010-1208-8","article-title":"The prognostic significance of non-sentinel lymph node metastasis in melanoma","volume":"17","author":"Brown","year":"2010","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib39","doi-asserted-by":"crossref","first-page":"423","DOI":"10.4161\/cbt.9.6.10996","article-title":"Histomorphologic parameters and CXCR4 mRNA and protein expression in sentinel node melanoma metastasis are correlated to clinical outcome","volume":"9","author":"Franco","year":"2010","journal-title":"Cancer Biol Ther"},{"key":"10.1016\/j.jss.2020.11.058_bib40","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1245\/s10434-009-0876-8","article-title":"Validation study of the s classification for melanoma patients with positive sentinel nodes: the Montreal experience","volume":"17","author":"Younan","year":"2010","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib41","doi-asserted-by":"crossref","first-page":"e500","DOI":"10.1016\/j.bjps.2009.07.043","article-title":"Evaluation of sentinel lymph nodes positive for melanoma for features predictive of non-sentinel nodal disease and patient prognosis: a 49 patient series","volume":"63","author":"Wright","year":"2010","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"10.1016\/j.jss.2020.11.058_bib42","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1002\/jso.21465","article-title":"Validation of a scoring system to predict non-sentinel lymph node metastasis in melanoma","volume":"101","author":"Cadili","year":"2010","journal-title":"J Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib43","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1245\/s10434-009-0884-8","article-title":"Influence of sentinel lymph node tumor burden on survival in melanoma","volume":"17","author":"Francischetto","year":"2010","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib44","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.jss.2008.06.012","article-title":"Prediction of nonsentinel lymph node metastasis in malignant melanoma","volume":"154","author":"Cadili","year":"2009","journal-title":"J Surg Res"},{"key":"10.1016\/j.jss.2020.11.058_bib45","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1097\/CMR.0b013e328329fe7d","article-title":"Radical dissection after positive groin sentinel biopsy in melanoma patients: rate of further positive nodes","volume":"19","author":"Santinami","year":"2009","journal-title":"Melanoma Res"},{"key":"10.1016\/j.jss.2020.11.058_bib46","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1245\/s10434-008-0187-5","article-title":"Positive nonsentinel node status predicts mortality in patients with cutaneous melanoma","volume":"16","author":"Ariyan","year":"2009","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib47","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1245\/s10434-009-0665-4","article-title":"Prognostic significance of a positive non-sentinel lymph node in melanoma","volume":"16","author":"Ghaferi","year":"2009","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib48","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1002\/jso.21066","article-title":"Sentinel lymph node micrometastasis may predict non-sentinel involvement in cutaneous melanoma patients","volume":"98","author":"Glumac","year":"2008","journal-title":"J Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib49","first-page":"64","article-title":"Microscopic tumor burden in sentinel lymph nodes predicts synchronous nonsentinel lymph node involvement in patients with melanoma","volume":"15","author":"Gershenwald","year":"2008","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib50","doi-asserted-by":"crossref","first-page":"1922","DOI":"10.1038\/sj.bjc.6604407","article-title":"The influence of sentinel lymph node tumour burden on additional lymph node involvement and disease-free survival in cutaneous melanoma - a retrospective analysis of 392 cases","volume":"98","author":"Guggenheim","year":"2008","journal-title":"Br J Cancer"},{"key":"10.1016\/j.jss.2020.11.058_bib51","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.ejso.2007.01.027","article-title":"Prediction of non-sentinel node status and outcome in sentinel node-positive melanoma patients","volume":"34","author":"Roka","year":"2008","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib52","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1245\/s10434-008-9888-z","article-title":"Criteria in sentinel lymph nodes of melanoma patients that predict involvement of nonsentinel lymph nodes","volume":"15","author":"Satzger","year":"2008","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib53","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1111\/j.1365-2133.2007.07937.x","article-title":"Sentinel lymph node biopsy in melanoma: a micromorphometric study relating to prognosis and completion lymph node dissection","volume":"157","author":"Debarbieux","year":"2007","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jss.2020.11.058_bib54","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/j.amjsurg.2006.08.062","article-title":"Size of sentinel node metastases predicts other nodal disease and survival in malignant melanoma","volume":"192","author":"Pearlman","year":"2006","journal-title":"Am J Surg"},{"key":"10.1016\/j.jss.2020.11.058_bib55","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1245\/s10434-006-9241-3","article-title":"Histological features of melanoma sentinel lymph node metastases associated with status of the completion lymphadenectomy and rate of subsequent relapse","volume":"14","author":"Govindarajan","year":"2007","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib56","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1001\/archsurg.139.4.400","article-title":"Is completion lymphadenectomy after a positive sentinel lymph node biopsy for cutaneous melanoma always necessary?","volume":"139","author":"Elias","year":"2004","journal-title":"Arch Surg"},{"key":"10.1016\/j.jss.2020.11.058_bib57","doi-asserted-by":"crossref","first-page":"162S","DOI":"10.1245\/ASO.2004.12.920","article-title":"Sentinel lymphonodectomy and S-classification: a successful strategy for better prediction and improvement of outcome of melanoma","volume":"11","author":"Starz","year":"2004","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib58","doi-asserted-by":"crossref","first-page":"3345","DOI":"10.1200\/JCO.2004.12.177","article-title":"The microanatomic location of metastatic melanoma in sentinel lymph nodes predicts nonsentinel lymph node involvement","volume":"22","author":"Dewar","year":"2004","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib59","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1002\/1097-0142(20000715)89:2<453::AID-CNCR34>3.0.CO;2-V","article-title":"Predicting sentinel and residual lymph node basin disease after sentinel lymph node biopsy for melanoma","volume":"89","author":"Wagner","year":"2000","journal-title":"Cancer"},{"key":"10.1016\/j.jss.2020.11.058_bib60","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1007\/s10434-000-0469-z","article-title":"Sentinel lymph node biopsy in cutaneous melanoma: the WHO Melanoma Program experience","volume":"7","author":"Cascinelli","year":"2000","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib61","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1067\/msy.2001.115830","article-title":"Factors that predict the presence of sentinel lymph node metastasis in patients with melanoma","volume":"130","author":"McMasters","year":"2001","journal-title":"Surgery"},{"key":"10.1016\/j.jss.2020.11.058_bib62","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1245\/s10434-013-3464-x","article-title":"Age as a predictor of sentinel node metastasis among patients with localized melanoma: an inverse correlation of melanoma mortality and incidence of sentinel node metastasis among young and old patients","volume":"21","author":"Balch","year":"2014","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib63","doi-asserted-by":"crossref","first-page":"2120","DOI":"10.1245\/s10434-015-4538-8","article-title":"Older age is associated with a higher incidence of melanoma death but a lower incidence of sentinel lymph node metastasis in the SEER databases (2003-2011)","volume":"22","author":"Cavanaugh-Hussey","year":"2015","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib64","doi-asserted-by":"crossref","first-page":"4296","DOI":"10.1200\/JCO.2007.15.4179","article-title":"Microscopic tumor burden in sentinel lymph nodes predicts synchronous nonsentinel lymph node involvement in patients with melanoma","volume":"26","author":"Gershenwald","year":"2008","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib65","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1245\/s10434-017-6143-5","article-title":"Prediction of non-sentinel node status in patients with melanoma and positive sentinel node biopsy: an Italian melanoma intergroup (IMI) study","volume":"25","author":"Rossi","year":"2018","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.jss.2020.11.058_bib66","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1111\/bjd.12688","article-title":"Blood microvessel density, lymphatic microvessel density and lymphatic invasion in predicting melanoma metastases: systematic review and meta-analysis","volume":"170","author":"Pastushenko","year":"2014","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jss.2020.11.058_bib67","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.ejca.2013.08.023","article-title":"The prognostic significance of sentinel node tumour burden in melanoma patients: an international, multicenter study of 1539 sentinel node-positive melanoma patients","volume":"50","author":"van der Ploeg","year":"2014","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.jss.2020.11.058_bib68","doi-asserted-by":"crossref","first-page":"6011","DOI":"10.1200\/JCO.2008.19.5420","article-title":"The Rotterdam criteria for sentinel node tumor load: the simplest prognostic factor?","volume":"26","author":"van Akkooi","year":"2008","journal-title":"J Clin Oncol"}],"container-title":["Journal of Surgical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022480420308052?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022480420308052?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T14:54:00Z","timestamp":1758380040000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022480420308052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":68,"alternative-id":["S0022480420308052"],"URL":"https:\/\/doi.org\/10.1016\/j.jss.2020.11.058","relation":{},"ISSN":["0022-4804"],"issn-type":[{"value":"0022-4804","type":"print"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Predictors of Nonsentinel Lymph Node Metastasis in Cutaneous Melanoma: A Systematic Review and Meta-Analysis","name":"articletitle","label":"Article Title"},{"value":"Journal of Surgical Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jss.2020.11.058","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}