{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T15:23:41Z","timestamp":1768836221024,"version":"3.49.0"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["UL1 TR002014"],"award-info":[{"award-number":["UL1 TR002014"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofsurgicalresearch.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Research"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.jss.2021.06.016","type":"journal-article","created":{"date-parts":[[2021,7,10]],"date-time":"2021-07-10T11:23:56Z","timestamp":1625916236000},"page":"527-535","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["CD163L1+CXCL10+ Macrophages are Enriched Within Colonic Lamina Propria of Diverticulitis Patients"],"prefix":"10.1016","volume":"267","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2688-8680","authenticated-orcid":false,"given":"Kathleen M.","family":"Schieffer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4804-7436","authenticated-orcid":false,"given":"Scott M.","family":"Emrich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1211-3040","authenticated-orcid":false,"given":"Gregory S.","family":"Yochum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walter A.","family":"Koltun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jss.2021.06.016_bib0001","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1080\/17474124.2018.1481746","article-title":"Pathophysiology of diverticular disease","volume":"12","author":"Schieffer","year":"2018","journal-title":"Expert Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.jss.2021.06.016_bib0002","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1055\/s-2004-832695","article-title":"Etiology and pathophysiology of diverticular disease","volume":"17","author":"Hobson","year":"2004","journal-title":"Clin Colon Rectal Surg"},{"key":"10.1016\/j.jss.2021.06.016_bib0003","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1053\/j.gastro.2009.01.015","article-title":"Burden of digestive diseases in the United States part II: lower gastrointestinal diseases","volume":"136","author":"Everhart","year":"2009","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jss.2021.06.016_bib0004","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1053\/j.gastro.2018.12.033","article-title":"Epidemiology, Pathophysiology, and Treatment of Diverticulitis","volume":"156","author":"Strate","year":"2019","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jss.2021.06.016_bib0005","doi-asserted-by":"crossref","first-page":"3110","DOI":"10.1111\/j.1572-0241.1999.01501.x","article-title":"Diagnosis and management of diverticular disease of the colon in adults. Ad Hoc Practice Parameters Committee of the American College of Gastroenterology","volume":"94","author":"Stollman","year":"1999","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.jss.2021.06.016_bib0006","doi-asserted-by":"crossref","first-page":"4013","DOI":"10.3748\/wjg.v16.i32.4013","article-title":"Health related quality of life after surgery for colonic diverticular disease","volume":"16","author":"Angriman","year":"2010","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.jss.2021.06.016_bib0007","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1053\/j.gastro.2011.02.012","article-title":"Interactions between the host innate immune system and microbes in inflammatory bowel disease","volume":"140","author":"Abraham","year":"2011","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jss.2021.06.016_bib0008","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1146\/annurev.immunol.17.1.593","article-title":"Mechanisms of phagocytosis in macrophages","volume":"17","author":"Aderem","year":"1999","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.jss.2021.06.016_bib0009","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/mi.2010.66","article-title":"Intestinal macrophages and response to microbial encroachment","volume":"4","author":"Smith","year":"2011","journal-title":"Mucosal Immunol"},{"key":"10.1016\/j.jss.2021.06.016_bib0010","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1615\/CritRevImmunol.v32.i6.10","article-title":"M1, M2 Macrophages: Oracles of Health and Disease","volume":"32","author":"Mills","year":"2012","journal-title":"Crit Rev Immunol"},{"key":"10.1016\/j.jss.2021.06.016_bib0011","doi-asserted-by":"crossref","first-page":"2399","DOI":"10.4049\/jimmunol.1103150","article-title":"CD163-L1 is an endocytic macrophage protein strongly regulated by mediators in the inflammatory response","volume":"188","author":"Moeller","year":"2012","journal-title":"J Immunol"},{"key":"10.1016\/j.jss.2021.06.016_bib0012","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1189\/jlb.3HI1114-531R","article-title":"CD163L1 and CLEC5A discriminate subsets of human resident and inflammatory macrophages in vivo","volume":"98","author":"Gonzalez-Dominguez","year":"2015","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.jss.2021.06.016_bib0013","doi-asserted-by":"crossref","first-page":"491","DOI":"10.3389\/fimmu.2014.00491","article-title":"Macrophage cytokines: involvement in immunity and infectious diseases","volume":"5","author":"Arango Duque","year":"2014","journal-title":"Front Immunol"},{"key":"10.1016\/j.jss.2021.06.016_bib0014","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/icb.2010.158","article-title":"CXCR3 ligands: redundant, collaborative and antagonistic functions","volume":"89","author":"Groom","year":"2011","journal-title":"Immunol Cell Biol"},{"key":"10.1016\/j.jss.2021.06.016_bib0015","doi-asserted-by":"crossref","first-page":"583","DOI":"10.3892\/ol.2011.300","article-title":"The emerging role of CXCL10 in cancer (Review)","volume":"2","author":"Liu","year":"2011","journal-title":"Oncol Lett"},{"key":"10.1016\/j.jss.2021.06.016_bib0016","first-page":"121","article-title":"CXCL10\/IP-10 in infectious diseases pathogenesis and potential therapeutic implications","volume":"22","author":"Liu","year":"2011","journal-title":"Cytokine Growth Factor Rev"},{"key":"10.1016\/j.jss.2021.06.016_bib0017","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1007\/s00423-011-0797-4","article-title":"Association of steroid use with complicated sigmoid diverticulitis: potential role of activated CD68+\/CD163+ macrophages","volume":"396","author":"von Rahden","year":"2011","journal-title":"Langenbecks Arch Surg"},{"key":"10.1016\/j.jss.2021.06.016_bib0018","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1136\/gutjnl-2016-312377","article-title":"Gut microbiota, metabolome and immune signatures in patients with uncomplicated diverticular disease","volume":"66","author":"Barbara","year":"2017","journal-title":"Gut"},{"key":"10.1016\/j.jss.2021.06.016_bib0019","doi-asserted-by":"crossref","first-page":"G277","DOI":"10.1152\/ajpgi.00136.2017","article-title":"RNA-seq implicates deregulation of the immune system in the pathogenesis of diverticulitis","volume":"313","author":"Schieffer","year":"2017","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.jss.2021.06.016_bib0020","doi-asserted-by":"crossref","first-page":"8467","DOI":"10.1038\/s41598-017-06787-8","article-title":"The Microbial ecosystem distinguishes chronically diseased tissue from adjacent tissue in the sigmoid colon of chronic, recurrent diverticulitis patients","volume":"7","author":"Schieffer","year":"2017","journal-title":"Sci Rep."},{"key":"10.1016\/j.jss.2021.06.016_bib0021","doi-asserted-by":"crossref","first-page":"5735","DOI":"10.1093\/nar\/gkq363","article-title":"Identification of {beta}-catenin binding regions in colon cancer cells using ChIP-Seq","volume":"38","author":"Bottomly","year":"2010","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jss.2021.06.016_bib0022","series-title":"ggplot2- Elegant Graphics for Data Analysis","author":"H","year":"2009"},{"key":"10.1016\/j.jss.2021.06.016_bib0023","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1038\/s41385-018-0126-0","article-title":"Two distinct colonic CD14(+) subsets characterized by single-cell RNA profiling in Crohn's disease","volume":"12","author":"Chapuy","year":"2019","journal-title":"Mucosal Immunol"},{"key":"10.1016\/j.jss.2021.06.016_bib0024","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/7420127","article-title":"Serum Cytokine Profiles in Children with Crohn's Disease","volume":"2016","author":"Vasilyeva","year":"2016","journal-title":"Mediators Inflamm"}],"container-title":["Journal of Surgical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022480421003851?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022480421003851?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T14:58:39Z","timestamp":1758380319000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022480421003851"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":24,"alternative-id":["S0022480421003851"],"URL":"https:\/\/doi.org\/10.1016\/j.jss.2021.06.016","relation":{},"ISSN":["0022-4804"],"issn-type":[{"value":"0022-4804","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"CD163L1+CXCL10+ Macrophages are Enriched Within Colonic Lamina Propria of Diverticulitis Patients","name":"articletitle","label":"Article Title"},{"value":"Journal of Surgical Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jss.2021.06.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}