{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T00:05:42Z","timestamp":1758413142864,"version":"3.44.0"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofsurgicalresearch.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Research"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.jss.2023.02.011","type":"journal-article","created":{"date-parts":[[2023,3,24]],"date-time":"2023-03-24T14:08:47Z","timestamp":1679666927000},"page":"148-156","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Analysis of Preoperative Predictors of Single and Multigland Primary Hyperparathyroidism"],"prefix":"10.1016","volume":"288","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4323-0696","authenticated-orcid":false,"given":"C. Corbin","family":"Frye","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sai Anusha","family":"Sanka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janessa","family":"Sullivan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. Michael","family":"Brunt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William E.","family":"Gillanders","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.K.","family":"Pandian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taylor C.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jss.2023.02.011_bib1","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1038\/nrendo.2017.104","article-title":"Primary hyperparathyroidism","volume":"14","author":"Walker","year":"2018","journal-title":"Nat Rev Endocrinol"},{"key":"10.1016\/j.jss.2023.02.011_bib2","first-page":"595","article-title":"Serum calcium and breast cancer risk: results from a prospective cohort study of 7,847 women","volume":"18","author":"Almquist","year":"2007","journal-title":"Cancer Causes Control"},{"key":"10.1016\/j.jss.2023.02.011_bib3","doi-asserted-by":"crossref","first-page":"103","DOI":"10.2147\/CLEP.S17298","article-title":"Breast cancer associated with primary hyperparathyroidism: a nested case control study","volume":"3","author":"Norenstedt","year":"2011","journal-title":"Clin Epidemiol"},{"key":"10.1016\/j.jss.2023.02.011_bib4","doi-asserted-by":"crossref","first-page":"142","DOI":"10.21037\/gs.2019.10.21","article-title":"Primary hyperparathyroidism and hypertension","volume":"9","author":"Fisher","year":"2020","journal-title":"Gland Surg"},{"key":"10.1016\/j.jss.2023.02.011_bib5","doi-asserted-by":"crossref","first-page":"7","DOI":"10.14740\/jnr564","article-title":"The association between hyperparathyroidism and ischemic stroke subtypes","volume":"10","author":"Onder","year":"2020","journal-title":"J Neurol Res"},{"key":"10.1016\/j.jss.2023.02.011_bib6","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0002-9343(97)00270-2","article-title":"Survival after the diagnosis of hyperparathyroidism: a population-based study","volume":"104","author":"Wermers","year":"1998","journal-title":"Am J Med"},{"key":"10.1016\/j.jss.2023.02.011_bib7","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0140-6736(87)91906-4","article-title":"Survival and renal function in untreated hypercalcaemia. Population-based cohort study with 14 years of follow-up","volume":"1","author":"Palmer","year":"1987","journal-title":"Lancet"},{"key":"10.1016\/j.jss.2023.02.011_bib8","first-page":"814","article-title":"The anatomy of primary hyperparathyroidism","volume":"92","author":"Thompson","year":"1982","journal-title":"Surgery"},{"key":"10.1016\/j.jss.2023.02.011_bib9","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/S0140-6736(17)31430-7","article-title":"Hyperparathyroidism","volume":"391","author":"Bilezikian","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.jss.2023.02.011_bib10","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1097\/00000658-200211000-00001","article-title":"Unilateral versus bilateral neck exploration for primary hyperparathyroidism: a prospective randomized controlled trial","volume":"236","author":"Bergenfelz","year":"2002","journal-title":"Ann Surg"},{"key":"10.1016\/j.jss.2023.02.011_bib11","first-page":"1024","article-title":"Success of unilateral neck exploration for sporadic primary hyperparathyroidism","volume":"114","author":"Worsey","year":"1993","journal-title":"Surgery"},{"key":"10.1016\/j.jss.2023.02.011_bib12","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1002\/lio2.223","article-title":"Routine bilateral neck exploration and four-gland dissection remains unnecessary in modern parathyroid surgery","volume":"4","author":"Walsh","year":"2019","journal-title":"Laryngoscope Investig Otolaryngol"},{"key":"10.1016\/j.jss.2023.02.011_bib13","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.soc.2015.08.012","article-title":"Minimally invasive parathyroidectomy versus bilateral neck exploration for primary hyperparathyroidism","volume":"25","author":"Laird","year":"2016","journal-title":"Surg Oncol Clin N Am"},{"key":"10.1016\/j.jss.2023.02.011_bib14","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/j.amjsurg.2014.05.006","article-title":"Fewer adverse events after reoperative parathyroidectomy associated with initial minimally invasive parathyroidectomy","volume":"208","author":"Morris","year":"2014","journal-title":"Am J Surg"},{"key":"10.1016\/j.jss.2023.02.011_bib15","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1097\/00000658-200205000-00008","article-title":"Six hundred fifty-six consecutive explorations for primary hyperparathyroidism","volume":"235","author":"Udelsman","year":"2002","journal-title":"Ann Surg"},{"key":"10.1016\/j.jss.2023.02.011_bib16","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1097\/SLA.0b013e318208fed9","article-title":"The superiority of minimally invasive parathyroidectomy based on 1650 consecutive patients with primary hyperparathyroidism","volume":"253","author":"Udelsman","year":"2011","journal-title":"Ann Surg"},{"key":"10.1016\/j.jss.2023.02.011_bib17","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1007\/s00423-008-0408-1","article-title":"Focused versus conventional parathyroidectomy for primary hyperparathyroidism: a prospective, randomized, blinded trial","volume":"393","author":"Slepavicius","year":"2008","journal-title":"Langenbecks Arch Surg"},{"key":"10.1016\/j.jss.2023.02.011_bib18","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1007\/s00268-013-2434-6","article-title":"Primary hyperparathyroidism: an analysis of failure of parathyroidectomy","volume":"38","author":"Bagul","year":"2014","journal-title":"World J Surg"},{"key":"10.1016\/j.jss.2023.02.011_bib19","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1001\/archsurg.141.8.777","article-title":"Predictors of single-gland vs multigland parathyroid disease in primary hyperparathyroidism: a simple and accurate scoring model","volume":"141","author":"Kebebew","year":"2006","journal-title":"Arch Surg"},{"key":"10.1016\/j.jss.2023.02.011_bib20","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1097\/SLA.0b013e31825ffbe1","article-title":"Creation of a \u201cWisconsin index\u201d nomogram to predict the likelihood of additional hyperfunctioning parathyroid glands during parathyroidectomy","volume":"257","author":"Mazeh","year":"2013","journal-title":"Ann Surg"},{"key":"10.1016\/j.jss.2023.02.011_bib21","doi-asserted-by":"crossref","first-page":"987","DOI":"10.3174\/ajnr.A4213","article-title":"Predictors of multigland disease in primary hyperparathyroidism: a scoring system with 4D-CT imaging and biochemical markers","volume":"36","author":"Sepahdari","year":"2015","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.jss.2023.02.011_bib22","doi-asserted-by":"crossref","first-page":"4205","DOI":"10.1245\/s10434-013-3190-4","article-title":"Multigland disease and slower decline in intraoperative PTH characterize mild primary hyperparathyroidism","volume":"20","author":"Schneider","year":"2013","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.jss.2023.02.011_bib23","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1007\/s00268-011-1377-z","article-title":"A predictive model of suitability for minimally invasive parathyroid surgery in the treatment of primary hyperparathyroidism [corrected]","volume":"36","author":"Kavanagh","year":"2012","journal-title":"World J Surg"},{"key":"10.1016\/j.jss.2023.02.011_bib24","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1245\/s10434-014-4080-0","article-title":"CaPTHUS scoring model in primary hyperparathyroidism: can it eliminate the need for ioPTH testing?","volume":"22","author":"Elfenbein","year":"2015","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.jss.2023.02.011_bib25","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s00423-017-1647-9","article-title":"Predictors of multiglandular disease in primary hyperparathyroidism","volume":"403","author":"Thier","year":"2018","journal-title":"Langenbecks Arch Surg"},{"key":"10.1016\/j.jss.2023.02.011_bib26","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1016\/j.surg.2004.06.062","article-title":"Detection of multiple gland primary hyperparathyroidism in the era of minimally invasive parathyroidectomy","volume":"136","author":"Sugg","year":"2004","journal-title":"Surgery"},{"key":"10.1016\/j.jss.2023.02.011_bib27","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1007\/s00268-009-0029-z","article-title":"Significance of biochemical parameters in differentiating uniglandular from multiglandular disease and limiting use of intraoperative parathormone assay","volume":"33","author":"Thakur","year":"2009","journal-title":"World J Surg"},{"key":"10.1016\/j.jss.2023.02.011_bib28","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.surg.2019.06.043","article-title":"Normocalcemic hyperparathyroidism: a collaborative endocrine surgery quality improvement program analysis","volume":"167","author":"Pandian","year":"2020","journal-title":"Surgery"},{"key":"10.1016\/j.jss.2023.02.011_bib29","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.amjsurg.2017.10.051","article-title":"Can parathyroid hyperplasia be predicted preoperatively?","volume":"215","author":"McHenry","year":"2018","journal-title":"Am J Surg"},{"key":"10.1016\/j.jss.2023.02.011_bib30","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1177\/172460089701200304","article-title":"A controversial problem: is there a relationship between parathyroid hormone level and parathyroid size in primary hyperparathyroidism?","volume":"12","author":"Locchi","year":"1997","journal-title":"Int J Biol Markers"},{"key":"10.1016\/j.jss.2023.02.011_bib31","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/0002-9610(92)90007-E","article-title":"The relationship between adenoma weight and intact (1-84) parathyroid hormone level in primary hyperparathyroidism","volume":"163","author":"Williams","year":"1992","journal-title":"Am J Surg"},{"key":"10.1016\/j.jss.2023.02.011_bib32","first-page":"1107","article-title":"The relation of serum calcium and immunoparathormone levels to parathyroid size and weight in primary hyperparathyroidism","volume":"98","author":"Rutledge","year":"1985","journal-title":"Surgery"},{"key":"10.1016\/j.jss.2023.02.011_bib33","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/0002-9343(81)90207-2","article-title":"Abnormal calcium-regulated PTH release in normal parathyroid tissue from patients with adenoma","volume":"71","author":"Brown","year":"1981","journal-title":"Am J Med"},{"key":"10.1016\/j.jss.2023.02.011_bib34","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1056\/NEJM199507273330407","article-title":"Calcium-ion-sensing cell-surface receptors","volume":"333","author":"Brown","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jss.2023.02.011_bib35","doi-asserted-by":"crossref","first-page":"E915","DOI":"10.1152\/ajpendo.00315.2009","article-title":"The calcium-sensing receptor (CaSR) defends against hypercalcemia independently of its regulation of parathyroid hormone secretion","volume":"297","author":"Kantham","year":"2009","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.jss.2023.02.011_bib36","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1046\/j.1365-2265.2000.01081.x","article-title":"Reduced vitamin D receptor expression in parathyroid adenomas: implications for pathogenesis","volume":"53","author":"Sudhaker Rao","year":"2000","journal-title":"Clin Endocrinol"},{"key":"10.1016\/j.jss.2023.02.011_bib37","doi-asserted-by":"crossref","first-page":"2034","DOI":"10.1172\/JCI114114","article-title":"Molecular cloning and chromosomal mapping of DNA rearranged with the parathyroid hormone gene in a parathyroid adenoma","volume":"83","author":"Arnold","year":"1989","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jss.2023.02.011_bib38","first-page":"1766","article-title":"Novel chromosomal abnormalities identified by comparative genomic hybridization in parathyroid adenomas","volume":"83","author":"Palanisamy","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jss.2023.02.011_bib39","first-page":"3775","article-title":"Alternative genetic pathways in parathyroid tumorigenesis","volume":"84","author":"Farnebo","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jss.2023.02.011_bib40","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1530\/EJE-13-0085","article-title":"Simultaneous expression analysis of vitamin D receptor, calcium-sensing receptor, cyclin D1, and PTH in symptomatic primary hyperparathyroidism in Asian Indians","volume":"169","author":"Varshney","year":"2013","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.jss.2023.02.011_bib41","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.ecl.2018.07.003","article-title":"Physiology of parathyroid hormone","volume":"47","author":"Goltzman","year":"2018","journal-title":"Endocrinol Metab Clin North Am"},{"key":"10.1016\/j.jss.2023.02.011_bib42","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1038\/sj.ki.5000148","article-title":"The renal Na+\/phosphate cotransporter NaPi-IIa is internalized via the receptor-mediated endocytic route in response to parathyroid hormone","volume":"69","author":"Bacic","year":"2006","journal-title":"Kidney Int"},{"key":"10.1016\/j.jss.2023.02.011_bib43","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1007\/s00423-021-02179-9","article-title":"Predictors of adenoma size and location in primary hyperparathyroidism","volume":"406","author":"Filser","year":"2021","journal-title":"Langenbecks Arch Surg"},{"key":"10.1016\/j.jss.2023.02.011_bib44","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1186\/s12893-020-00922-5","article-title":"Correlation of perioperative biochemical variables with single adenoma weight in patients with primary hyperparathyroidism","volume":"20","author":"Papadakis","year":"2020","journal-title":"BMC Surg"},{"key":"10.1016\/j.jss.2023.02.011_bib45","article-title":"Isolated hypophosphataemia as an early marker of primary hyperparathyroidism","volume":"2021","author":"Alexander","year":"2021","journal-title":"Endocrinol Diabetes Metab Case Rep"},{"key":"10.1016\/j.jss.2023.02.011_bib46","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.surg.2016.03.038","article-title":"Normohormonal primary hyperparathyroidism is a distinct form of primary hyperparathyroidism","volume":"161","author":"Applewhite","year":"2017","journal-title":"Surgery"},{"key":"10.1016\/j.jss.2023.02.011_bib47","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1007\/s00268-018-4512-2","article-title":"Classic primary hyperparathyroidism versus normocalcemic and normohormonal variants: do they really differ?","volume":"42","author":"Kiriakopoulos","year":"2018","journal-title":"World J Surg"},{"key":"10.1016\/j.jss.2023.02.011_bib48","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1007\/s00423-019-01782-1","article-title":"Mild sporadic primary hyperparathyroidism: high rate of multiglandular disease is associated with lower surgical cure rate","volume":"404","author":"Tr\u00e9bouet","year":"2019","journal-title":"Langenbecks Arch Surg"},{"key":"10.1016\/j.jss.2023.02.011_bib49","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1093\/bmb\/ldy042","article-title":"Mild primary hyperparathyroidism-to treat or not to treat?","volume":"129","author":"Hassan-Smith","year":"2019","journal-title":"Br Med Bull"},{"key":"10.1016\/j.jss.2023.02.011_bib50","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1634\/theoncologist.2014-0084","article-title":"Mild primary hyperparathyroidism: a literature review","volume":"19","author":"Applewhite","year":"2014","journal-title":"Oncologist"},{"key":"10.1016\/j.jss.2023.02.011_bib51","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1177\/0194599820983728","article-title":"Normocalcemic and normohormonal primary hyperparathyroidism: laboratory values and end-organ effects","volume":"165","author":"Hollowoa","year":"2021","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.jss.2023.02.011_bib52","doi-asserted-by":"crossref","first-page":"861","DOI":"10.21037\/gs-20-857","article-title":"Usefulness of the Wisconsin and CaPTHUS indices for predicting multiglandular disease in patients with primary hyperparathyroidism in a southern European population","volume":"10","author":"Serradilla-Mart\u00edn","year":"2021","journal-title":"Gland Surg"}],"container-title":["Journal of Surgical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022480423000574?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022480423000574?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T15:02:16Z","timestamp":1758380536000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022480423000574"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":52,"alternative-id":["S0022480423000574"],"URL":"https:\/\/doi.org\/10.1016\/j.jss.2023.02.011","relation":{},"ISSN":["0022-4804"],"issn-type":[{"type":"print","value":"0022-4804"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Analysis of Preoperative Predictors of Single and Multigland Primary Hyperparathyroidism","name":"articletitle","label":"Article Title"},{"value":"Journal of Surgical Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jss.2023.02.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}