{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T12:06:16Z","timestamp":1791893176657,"version":"4.3.4"},"reference-count":19,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["KL2 TR003108"],"award-info":[{"award-number":["KL2 TR003108"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 GM 111324"],"award-info":[{"award-number":["R01 GM 111324"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["TL1 TR003109"],"award-info":[{"award-number":["TL1 TR003109"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["UL1 TR003107"],"award-info":[{"award-number":["UL1 TR003107"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofsurgicalresearch.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Research"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1016\/j.jss.2023.04.019","type":"journal-article","created":{"date-parts":[[2023,6,6]],"date-time":"2023-06-06T13:21:37Z","timestamp":1686057697000},"page":"209-214","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Weight-Based Dosing for Venous Thromboembolism Prophylaxis in Spinal Trauma Patients Appears Safe"],"prefix":"10.1016","volume":"290","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2216-7592","authenticated-orcid":false,"given":"Thomas","family":"Heye","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarendeep","family":"Thind","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison","family":"Jenkins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Reif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna K.","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Sexton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle","family":"Kalkwarf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avi","family":"Bhavaraju","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jss.2023.04.019_bib1","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.thromres.2017.10.016","article-title":"Optimal timing of starting thromboprophylaxis for patients with acute spinal cord injury: a survey of Canadian spine surgeons","volume":"160","author":"Siavash","year":"2017","journal-title":"Thromb Res"},{"key":"10.1016\/j.jss.2023.04.019_bib2","doi-asserted-by":"crossref","first-page":"S276","DOI":"10.21037\/cdt.2017.09.01","article-title":"Deep vein thrombosis: pathogenesis, diagnosis, and medical management","volume":"7","author":"Stone","year":"2017","journal-title":"Cardiovasc Diagn Ther"},{"key":"10.1016\/j.jss.2023.04.019_bib3","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1053\/j.jfas.2021.03.010","article-title":"Thromboprophylaxis and bleeding complications in orthopedic and trauma patients: a systemic Review","volume":"60","author":"Villareal","year":"2021","journal-title":"J Foot Ankle Surg"},{"key":"10.1016\/j.jss.2023.04.019_bib4","doi-asserted-by":"crossref","first-page":"E39","DOI":"10.1093\/neuros\/nyy367","article-title":"Congress of neurological surgeons systematic review and evidence-based guidelines on the evaluation and treatment of patients with thoracolumbar spine trauma: prophylaxis and treatment of thromboembolic events","volume":"84","author":"Raksin","year":"2019","journal-title":"Neurosurgery"},{"key":"10.1016\/j.jss.2023.04.019_bib6","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1097\/BRS.0000000000003664","article-title":"Lower mortality and morbidity with low-molecular-weight heparin for venous thromboembolism prophylaxis in spine trauma","volume":"45","author":"Neifert","year":"2020","journal-title":"Spine"},{"key":"10.1016\/j.jss.2023.04.019_bib7","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1056\/NEJM199609053351003","article-title":"A comparison of low-dose heparin with low-molecular-weight heparin as prophylaxis against venous thromboembolism after major trauma","volume":"335","author":"Geerts","year":"1996","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jss.2023.04.019_bib8","series-title":"Venous Thromboembolism Prophylaxis Guidelines for Trauma & Emergency General surgery. Trauma and critical care services manual","author":"Kalkwarf","year":"2019"},{"key":"10.1016\/j.jss.2023.04.019_bib9","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1146\/annurev.publhealth.23.100901.140546","article-title":"The importance of the normality assumption in large public health data sets","volume":"23","author":"Lumley","year":"2002","journal-title":"Annu Rev Publ Health"},{"key":"10.1016\/j.jss.2023.04.019_bib10","doi-asserted-by":"crossref","first-page":"E1","DOI":"10.1530\/EJE-19-0922","article-title":"Who is afraid of non-normal data? Choosing between parametric and non-parametric tests","volume":"182","author":"le Cessie","year":"2020","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.jss.2023.04.019_bib11","doi-asserted-by":"crossref","first-page":"489","DOI":"10.5435\/JAAOS-D-17-00561","article-title":"Venous thromboembolism prophylaxis in spine surgery","volume":"26","author":"Kepler","year":"2018","journal-title":"J Am Acad Orthop Surg"},{"key":"10.1016\/j.jss.2023.04.019_bib12","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1097\/TA.0000000000002830","article-title":"Updated guidelines to reduce venous thromboembolism in trauma patients: a western trauma association critical decisions algorithm","volume":"89","author":"Ley","year":"2020","journal-title":"J Trauma Acute Care Surg"},{"key":"10.1016\/j.jss.2023.04.019_bib13","doi-asserted-by":"crossref","first-page":"e000643","DOI":"10.1136\/tsaco-2020-000643","article-title":"Venous thromboembolism prophylaxis in the trauma intensive care unit: an American association for the surgery of trauma critical care committee clinical consensus document","volume":"6","author":"Rappold","year":"2021","journal-title":"Trauma Surg acute Care open"},{"key":"10.1016\/j.jss.2023.04.019_bib14","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1097\/BRS.0000000000000754","article-title":"Early pharmacological venous thromboembolism prophylaxis is safe after operative fixation of traumatic spine fractures","volume":"40","author":"Kim","year":"2015","journal-title":"Spine"},{"key":"10.1016\/j.jss.2023.04.019_bib15","doi-asserted-by":"crossref","first-page":"407","DOI":"10.14245\/ns.1938420.210","article-title":"Venous thromboembolism chemoprophylaxis within 24 hours of surgery for spinal cord injury: is it safe and effective?","volume":"17","author":"Ahlquist","year":"2020","journal-title":"Neurospine"},{"key":"10.1016\/j.jss.2023.04.019_bib16","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1097\/TA.0b013e3182788fa7","article-title":"Dose adjusting enoxaparin is necessary to achieve adequate venous thromboembolism prophylaxis in trauma patients","volume":"74","author":"Costantini","year":"2013","journal-title":"J Trauma acute Care Surg"},{"key":"10.1016\/j.jss.2023.04.019_bib17","first-page":"874","article-title":"Standard prophylactic enoxaparin dosing leads to inadequate anti-Xa levels and increased deep venous thrombosis rates in critically ill trauma and surgical patients","volume":"68","author":"Malinoski","year":"2010","journal-title":"J Trauma"},{"key":"10.1016\/j.jss.2023.04.019_bib18","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s00068-019-01215-0","article-title":"Weight-based enoxaparin with anti-factor xa assay-based dose adjustment for venous thromboembolic event prophylaxis in adult trauma patients results in improved prophylactic range targeting","volume":"47","author":"Rodier","year":"2021","journal-title":"Eur J Trauma Emerg Surg"},{"key":"10.1016\/j.jss.2023.04.019_bib19","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/j.amjsurg.2013.07.020","article-title":"Weight-based enoxaparin dosing for venous thromboembolism prophylaxis in the obese trauma patient","volume":"206","author":"Bickford","year":"2013","journal-title":"Am J Surg"},{"key":"10.1016\/j.jss.2023.04.019_bib21","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1097\/00005373-200207000-00032","article-title":"Practice management guidelines for the prevention of venous thromboembolism in trauma patients: the EAST practice management guidelines work group","volume":"53","author":"Rogers","year":"2002","journal-title":"J Trauma"}],"updated-by":[{"DOI":"10.1016\/j.jss.2025.04.016","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000}}],"container-title":["Journal of Surgical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022480423001920?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022480423001920?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T15:03:27Z","timestamp":1758380607000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022480423001920"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":19,"alternative-id":["S0022480423001920"],"URL":"https:\/\/doi.org\/10.1016\/j.jss.2023.04.019","relation":{},"ISSN":["0022-4804"],"issn-type":[{"value":"0022-4804","type":"print"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Weight-Based Dosing for Venous Thromboembolism Prophylaxis in Spinal Trauma Patients Appears Safe","name":"articletitle","label":"Article Title"},{"value":"Journal of Surgical Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jss.2023.04.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}