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In comparison, less is known about the relationship between hypersexuality and sexual arousal at the state level. Also, previous research has revealed a relationship between hypersexuality and negative mood. However, the possibility that sexual response might not be as negatively impacted by negative mood in hypersexual individuals has, as yet, not been tested.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Aim<\/jats:title>\n                  <jats:p>The purpose of this study was to investigate sexual responsivity and the effects of negative mood on sexual arousal in hypersexual men who have sex with men (MSM).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A total of 211 MSM were assigned to a hypersexuality (N = 81) or a control (N = 130) group using an interview patterned with a semi-structured Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders format. Participants filled out questionnaires and were shown neutral, sexual, and anxiety- and sadness-inducing films.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Outcomes<\/jats:title>\n                  <jats:p>Changes in penile circumference and self-reported sexual arousal were the primary outcomes analyzed in this study.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Controlling for age and HIV status, no differences were found in genital response between hypersexual and non-hypersexual men. Also, the 2 groups did not differ in subjective sexual arousal. Moreover, no effects of negative mood were found. Time series clustering analyses revealed 3 groups\u2014low responders and slow and fast high responders. Sexual excitation, but not sexual compulsivity or pornography use, predicted cluster membership.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Clinical Translation<\/jats:title>\n                  <jats:p>Hypersexual MSM may benefit more from an exploration of motivational and behavioral, as compared to psychophysiological, mechanisms underlying possible links between (negative) mood and sexual behavior.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Strengths &amp; Limitations<\/jats:title>\n                  <jats:p>Strengths of the study include its sample size, making it one of the larger psychophysiological sex studies; the use of clinical interviews for group assignment; the inclusion of genital response measures; and the application of time series clustering to examine differences among participants. Limitations include possible sample heterogeneity and the reliance on researcher-selected stimuli.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Given the lack of any effects of negative mood on sexual response in hypersexual MSM, future studies could explore in more depth possible motivational and behavioral effects, including, for example, the impact of negative mood on the tendency to seek out sex as a form of distraction or for validation or emotional support.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1016\/j.jsxm.2020.05.005","type":"journal-article","created":{"date-parts":[[2020,7,9]],"date-time":"2020-07-09T01:42:12Z","timestamp":1594258932000},"page":"1751-1760","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Sexual Responsivity and the Effects of Negative Mood on Sexual Arousal in Hypersexual Men Who Have Sex with Men (MSM)"],"prefix":"10.1093","volume":"17","author":[{"given":"Erick","family":"Janssen","sequence":"first","affiliation":[{"name":"Institute for Family and Sexuality Studies , Leuven , Belgium"},{"name":"Department of Neurosciences , Leuven , Belgium"},{"name":"University of Leuven , Leuven , Belgium"},{"name":"Kinsey Institute , , IN , USA"},{"name":"Indiana University , , IN , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Prause","sequence":"additional","affiliation":[{"name":"Liberos , Los Angeles, CA , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Swinburne Romine","sequence":"additional","affiliation":[{"name":"The Schiefelbusch Institute for Life Span Studies , Lawrence, KS , USA"},{"name":"University of Kansas , Lawrence, KS , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Raymond","sequence":"additional","affiliation":[{"name":"Department of Psychiatry , Madison, WI , USA"},{"name":"University of Wisconsin , Madison, WI , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"Angus","family":"MacDonald","sequence":"additional","affiliation":[{"name":"Department of Psychology , Minneapolis, MN , USA"},{"name":"University of Minnesota , Minneapolis, MN , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eli","family":"Coleman","sequence":"additional","affiliation":[{"name":"Department of Family Medicine and Community Health , Minneapolis, MN , USA"},{"name":"University of Minnesota , Minneapolis, MN , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael H.","family":"Miner","sequence":"additional","affiliation":[{"name":"Department of Family Medicine and Community Health , Minneapolis, MN , USA"},{"name":"University of Minnesota , Minneapolis, MN , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,7,8]]},"reference":[{"key":"2023011111131913100_bib1","article-title":"International classification of diseases for mortality and morbidity statistics (11th Revision)","author":"World Health Organization"},{"key":"2023011111131913100_bib2","article-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association","year":"2013","edition":"Fifth Edition"},{"key":"2023011111131913100_bib3","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1007\/s10508-014-0326-y","article-title":"What happened to hypersexual disorder","volume":"43","author":"Kafka","year":"2014","journal-title":"Arch Sex Behav"},{"key":"2023011111131913100_bib4","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1080\/00224490409552230","article-title":"Sexual addiction, sexual compulsivity, sexual impulsivity, or what? 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