{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,23]],"date-time":"2024-06-23T06:32:47Z","timestamp":1719124367065},"reference-count":57,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2010,12,1]],"date-time":"2010-12-01T00:00:00Z","timestamp":1291161600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Theoretical Biology"],"published-print":{"date-parts":[[2010,12]]},"DOI":"10.1016\/j.jtbi.2010.08.033","type":"journal-article","created":{"date-parts":[[2010,9,13]],"date-time":"2010-09-13T10:21:59Z","timestamp":1284373319000},"page":"426-436","source":"Crossref","is-referenced-by-count":13,"title":["Modeling immune complex-mediated autoimmune inflammation"],"prefix":"10.1016","volume":"267","author":[{"given":"A.","family":"Arazi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.U.","family":"Neumann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtbi.2010.08.033_bib1","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1038\/ki.1990.14","article-title":"Lupus nephritis: correlation of interstitial cells with glomerular function","volume":"37","author":"Alexopoulos","year":"1990","journal-title":"Kidney Int."},{"key":"10.1016\/j.jtbi.2010.08.033_bib2","doi-asserted-by":"crossref","first-page":"2682","DOI":"10.1002\/1529-0131(199912)42:12<2682::AID-ANR26>3.0.CO;2-6","article-title":"Patterns of disease activity in systemic lupus erythematosus","volume":"42","author":"Barr","year":"1999","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jtbi.2010.08.033_bib3","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1098\/rspb.1995.0025","article-title":"A minimal model for T-cell vaccination","volume":"259","author":"Borghans","year":"1995","journal-title":"Proc. Biol. Sci."},{"key":"10.1016\/j.jtbi.2010.08.033_bib4","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.4049\/jimmunol.161.3.1087","article-title":"T cell vaccination in experimental autoimmune encephalomyelitis: a mathematical model","volume":"161","author":"Borghans","year":"1998","journal-title":"J. Immunol."},{"key":"10.1016\/j.jtbi.2010.08.033_bib5","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1078\/0171-2985-00141","article-title":"C1q, autoimmunity and apoptosis","volume":"205","author":"Botto","year":"2002","journal-title":"Immunobiology"},{"key":"10.1016\/j.jtbi.2010.08.033_bib6","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.cam.2004.10.025","article-title":"Immunological self-tolerance: lessons from mathematical modeling","volume":"184","author":"Carneiro","year":"2005","journal-title":"J. Comput. Appl. Math."},{"key":"10.1016\/j.jtbi.2010.08.033_bib7","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1159\/000313054","article-title":"The cellular basis of immunologic memory","volume":"15","author":"Celada","year":"1971","journal-title":"Prog. Allergy"},{"key":"10.1016\/j.jtbi.2010.08.033_bib8","first-page":"439","article-title":"Definition clinical relevance of antibodies to nuclear ribonucleoprotein and other nuclear antigens in patients with cryptogenic fibrosing alveolitis","volume":"130","author":"Chapman","year":"1984","journal-title":"Am. Rev. Respir. Dis."},{"key":"10.1016\/j.jtbi.2010.08.033_bib9","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.smim.2006.12.005","article-title":"Regulation of lupus-related autoantibody production and clinical disease by Toll-like receptors","volume":"19","author":"Christensen","year":"2007","journal-title":"Semin. Immunol."},{"key":"10.1016\/j.jtbi.2010.08.033_bib10","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1126\/science.279.5353.1052","article-title":"Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis","volume":"279","author":"Clynes","year":"1998","journal-title":"Science"},{"issue":"Suppl. 1","key":"10.1016\/j.jtbi.2010.08.033_bib11","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1159\/000195495","article-title":"Study of immune complexes in bronchoalveolar lavage fluids","volume":"54","author":"Dall\u2019Aglio","year":"1988","journal-title":"Respiration"},{"key":"10.1016\/j.jtbi.2010.08.033_bib12","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1093\/rheumatology\/35.1.5","article-title":"Michael Mason Prize Essay 1995. Complement, immune complexes and systemic lupus erythematosus","volume":"35","author":"Davies","year":"1996","journal-title":"Br. J. Rheumatol."},{"key":"10.1016\/j.jtbi.2010.08.033_bib13","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/BF02458444","article-title":"Memory but no suppression in low-dimensional symmetric idiotypic networks","volume":"51","author":"De Boer","year":"1988","journal-title":"Bull. Math. Biol."},{"key":"10.1016\/j.jtbi.2010.08.033_bib14","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1007\/BF02460115","article-title":"Unreasonable implications of reasonable idiotypic network assumptions","volume":"51","author":"De Boer","year":"1989","journal-title":"Bull. Math. Biol."},{"key":"10.1016\/j.jtbi.2010.08.033_bib15","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1007\/BF02460672","article-title":"Immune network behavior I. From stationary states to limit cycle oscillations","volume":"55","author":"De Boer","year":"1993","journal-title":"Bull. Math. Biol."},{"key":"10.1016\/j.jtbi.2010.08.033_bib16","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1007\/BF02460673","article-title":"Immune network behavior II. From oscillations to chaos and stationary states","volume":"55","author":"De Boer","year":"1993","journal-title":"Bull. Math. Biol."},{"issue":"Suppl. 2","key":"10.1016\/j.jtbi.2010.08.033_bib17","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1007\/BF02215852","article-title":"B lymphocytes and humoral immune responses in rheumatoid arthritis","volume":"14","author":"De Clerck","year":"1995","journal-title":"Clin. Rheumatol."},{"key":"10.1016\/j.jtbi.2010.08.033_bib18","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1517\/14712598.8.11.1805","article-title":"Belimumab, an anti-BLyS human monoclonal antibody for potential treatment of inflammatory autoimmune diseases","volume":"8","author":"Ding","year":"2008","journal-title":"Expert Opin. Biol. Ther."},{"key":"10.1016\/j.jtbi.2010.08.033_bib19","series-title":"Simulating, Analyzing, and Animating Dynamical Systems: A Guide to XPPAUT for Researchers and Students","author":"Ermentrout","year":"2002"},{"key":"10.1016\/j.jtbi.2010.08.033_bib20","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1172\/JCI117745","article-title":"Modulation of neutrophil influx in glomerulonephritis in the rat with anti-macrophage inflammatory protein-2 (MIP-2) antibody","volume":"95","author":"Feng","year":"1995","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.jtbi.2010.08.033_bib21","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/s00285-008-0165-3","article-title":"Dynamic hematological disease: a review","volume":"58","author":"Foley","year":"2009","journal-title":"J. Math. Biol."},{"key":"10.1016\/j.jtbi.2010.08.033_bib22","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.2337\/diabetes.48.9.1677","article-title":"Onset of type 1 diabetes: a dynamical instability","volume":"48","author":"Freiesleben De Blasio","year":"1999","journal-title":"Diabetes"},{"key":"10.1016\/j.jtbi.2010.08.033_bib23","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/S1568-9972(02)00101-5","article-title":"Dosage and characterization of circulating DNA: present usage and possible applications in systemic autoimmune disorders","volume":"2","author":"Galeazzi","year":"2002","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.jtbi.2010.08.033_bib24","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.4049\/jimmunol.156.3.1151","article-title":"Blood clearance kinetics and liver uptake of mononucleosomes in mice","volume":"156","author":"Gauthier","year":"1996","journal-title":"J. Immunol."},{"key":"10.1016\/j.jtbi.2010.08.033_bib25","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1007\/s10165-005-0430-x","article-title":"Removal of dying cells and systemic lupus erythematosus","volume":"15","author":"Grossmayer","year":"2005","journal-title":"Mod. Rheumatol."},{"key":"10.1016\/j.jtbi.2010.08.033_bib26","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0022-2143(96)90114-6","article-title":"Mechanism computer simulation of immune complex formation, opsonization, and clearance","volume":"128","author":"Head","year":"1996","journal-title":"J. Lab. Clin. Med."},{"key":"10.1016\/j.jtbi.2010.08.033_bib27","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/j.1540-9740.2003.02214.x","article-title":"Polyarteritis nodosa and cutaneous polyarteritis nodosa","volume":"2","author":"Herbert","year":"2003","journal-title":"Skinmed"},{"key":"10.1016\/j.jtbi.2010.08.033_bib28","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/j.jtbi.2007.01.020","article-title":"Dynamical properties of autoimmune disease models: tolerance, flare-up, dormancy","volume":"246","author":"Iwami","year":"2007","journal-title":"J. Theor. Biol."},{"key":"10.1016\/j.jtbi.2010.08.033_bib29","first-page":"631","article-title":"Mechanism of formation of subepithelial electron-dense deposits in active in situ immune complex glomerulonephritis","volume":"136","author":"Kagami","year":"1990","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.jtbi.2010.08.033_bib30","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1038\/ki.1986.264","article-title":"Interaction of immune complexes with glomerular heparan sulfate-proteoglycans","volume":"30","author":"Kanwar","year":"1986","journal-title":"Kidney Int."},{"key":"10.1016\/j.jtbi.2010.08.033_bib31","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.jtbi.2008.09.019","article-title":"The role of low avidity T cells in the protection against type 1 diabetes: a modeling investigation","volume":"256","author":"Khadra","year":"2009","journal-title":"J. Theor. Biol."},{"key":"10.1016\/j.jtbi.2010.08.033_bib32","doi-asserted-by":"crossref","first-page":"91","DOI":"10.4049\/jimmunol.137.1.91","article-title":"Mononuclear phagocyte function in SLE. I. Bipartite Fc- and complement-dependent dysfunction","volume":"137","author":"Kimberly","year":"1986","journal-title":"J. Immunol."},{"key":"10.1016\/j.jtbi.2010.08.033_bib33","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.autrev.2006.10.003","article-title":"Autonomic paraneoplastic neurological syndromes","volume":"6","author":"Lorusso","year":"2007","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.jtbi.2010.08.033_bib34","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1007\/s10875-004-6245-2","article-title":"A peptide based on the complementarity determining region 1 of a human monoclonal autoantibody ameliorates spontaneous and induced lupus manifestations in correlation with cytokine immunomodulation","volume":"24","author":"Luger","year":"2004","journal-title":"J. Clin. Immunol."},{"key":"10.1016\/j.jtbi.2010.08.033_bib35","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1137\/060661144","article-title":"Modeling cyclic waves of circulating T-cells in autoimmune diabetes","volume":"67","author":"Mahaffy","year":"2007","journal-title":"SIAM J. Appl. Math."},{"key":"10.1016\/j.jtbi.2010.08.033_bib36","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1084\/jem.157.5.1516","article-title":"Rearrangement of immune complexes in glomeruli leads to persistence and development of electron-dense deposits","volume":"157","author":"Mannik","year":"1983","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.jtbi.2010.08.033_bib37","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1152\/japplphysiol.00514.2007","article-title":"A quantitative comparison of rates of phagocytosis and digestion of apoptotic cells by macrophages from normal (BALB\/c) and diabetes-prone (NOD) mice","volume":"104","author":"Mar\u00e9e","year":"2008","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.jtbi.2010.08.033_bib38","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1098\/rsta.2006.1769","article-title":"Modelling the onset of Type 1 diabetes: can impaired macrophage phagocytosis make the difference between health and disease? Philos","volume":"364","author":"Mar\u00e9e","year":"2006","journal-title":"Transact. A Math. Phys. Eng. Sci."},{"key":"10.1016\/j.jtbi.2010.08.033_bib39","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1093\/rheumatology\/keh693","article-title":"Sle\u2014a disease of clearance deficiency?","volume":"44","author":"Munoz","year":"2005","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.jtbi.2010.08.033_bib40","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1046\/j.1365-2249.2001.01459.x","article-title":"Immune complex processing in C1q-deficient mice","volume":"123","author":"Nash","year":"2001","journal-title":"Clin. Exp. Immunol."},{"issue":"Suppl. 1","key":"10.1016\/j.jtbi.2010.08.033_bib41","first-page":"16","article-title":"Mechanisms of pancreatic beta-cell destruction in type I diabetes","volume":"11","author":"Nerup","year":"1988","journal-title":"Diabetes Care"},{"issue":"Suppl. 5","key":"10.1016\/j.jtbi.2010.08.033_bib42","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1093\/ndt\/16.suppl_5.3","article-title":"The role of macrophages in glomerulonephritis","volume":"16","author":"Nikolic-Paterson","year":"2001","journal-title":"Nephrol. Dial. Transplant."},{"key":"10.1016\/j.jtbi.2010.08.033_bib43","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1038\/nrd1175","article-title":"Anti-TNF-alpha therapies: the next generation","volume":"2","author":"Palladino","year":"2003","journal-title":"Nat. Rev. Drug. Discov."},{"key":"10.1016\/j.jtbi.2010.08.033_bib44","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/0025-5564(80)90017-6","article-title":"Receptor clustering on a cell-surface. I. Theory of receptor cross-linking by ligands bearing 2 chemically identical functional groups","volume":"48","author":"Perelson","year":"1980","journal-title":"Math. Biosci."},{"key":"10.1016\/j.jtbi.2010.08.033_bib45","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1172\/JCI109992","article-title":"Quantitation and characterization of plasma DNA in normals and patients with systemic lupus erythematosus","volume":"66","author":"Raptis","year":"1980","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.jtbi.2010.08.033_bib46","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1146\/annurev.immunol.19.1.275","article-title":"IgG Fc receptors","volume":"19","author":"Ravetch","year":"2001","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.jtbi.2010.08.033_bib47","doi-asserted-by":"crossref","first-page":"3399","DOI":"10.1002\/art.22947","article-title":"Opsonization of late apoptotic cells by systemic lupus erythematosus autoantibodies inhibits their uptake via an Fcgamma receptor-dependent mechanism","volume":"56","author":"Reefman","year":"2007","journal-title":"Arthritis. Rheum."},{"key":"10.1016\/j.jtbi.2010.08.033_bib48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.humimm.2003.09.013","article-title":"Pathogenesis of diseases associated with antineutrophil cytoplasm autoantibodies","volume":"65","author":"Reumaux","year":"2004","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.jtbi.2010.08.033_bib49","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.jtbi.2006.02.016","article-title":"A reduced mathematical model of the acute inflammatory response: I. Derivation of model and analysis of anti-inflammation","volume":"242","author":"Reynolds","year":"2006","journal-title":"J. Theor. Biol."},{"key":"10.1016\/j.jtbi.2010.08.033_bib50","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1172\/JCI118552","article-title":"Fc gamma RIIA alleles are heritable risk factors for lupus nephritis in African Americans","volume":"97","author":"Salmon","year":"1996","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.jtbi.2010.08.033_bib51","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1191\/0961203302lu311rr","article-title":"Lowering anti-dsDNA antibodies\u2014what's new?","volume":"11","author":"Schiffer","year":"2002","journal-title":"Lupus"},{"key":"10.1016\/j.jtbi.2010.08.033_bib52","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1084\/jem.169.6.1879","article-title":"Histones have high affinity for the glomerular basement membrane. Relevance for immune complex formation in lupus nephritis","volume":"169","author":"Schmiedeke","year":"1989","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.jtbi.2010.08.033_bib53","doi-asserted-by":"crossref","first-page":"3009","DOI":"10.4049\/jimmunol.158.6.3009","article-title":"Kinetics of cytokine production in experimental systemic lupus erythematosus: involvement of T helper cell 1\/T helper cell 2-type cytokines in disease","volume":"15","author":"Segal","year":"1997","journal-title":"J. Immunol."},{"key":"10.1016\/j.jtbi.2010.08.033_bib54","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0301-4622(98)00136-7","article-title":"Multiple attractors in immunology: theory and experiment","volume":"72","author":"Segel","year":"1998","journal-title":"Biophys. Chem."},{"key":"10.1016\/j.jtbi.2010.08.033_bib55","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1136\/ard.45.5.359","article-title":"Predictive value of complement profiles and anti-dsDNA in systemic lupus erythematosus","volume":"45","author":"Swaak","year":"1986","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jtbi.2010.08.033_bib56","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1038\/icb.1994.71","article-title":"Beta 2 integrin independent neutrophil recruitment and injury in anti-GBM glomerulonephritis in rabbits","volume":"72","author":"Tipping","year":"1994","journal-title":"Immunol. Cell. Biol."},{"key":"10.1016\/j.jtbi.2010.08.033_bib57","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1038\/75963","article-title":"Lupus, DNase, and defective disposal of cellular debris","volume":"25","author":"Walport","year":"2000","journal-title":"Nat. Genet."}],"container-title":["Journal of Theoretical Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002251931000456X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002251931000456X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,6,3]],"date-time":"2023-06-03T08:04:38Z","timestamp":1685779478000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002251931000456X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,12]]},"references-count":57,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["S002251931000456X"],"URL":"https:\/\/doi.org\/10.1016\/j.jtbi.2010.08.033","relation":{},"ISSN":["0022-5193"],"issn-type":[{"value":"0022-5193","type":"print"}],"subject":[],"published":{"date-parts":[[2010,12]]}}}