{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T13:06:24Z","timestamp":1769605584615,"version":"3.49.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,2,28]],"date-time":"2017-02-28T00:00:00Z","timestamp":1488240000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"University of Lagos"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Traditional and Complementary Medicine"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.jtcme.2017.02.006","type":"journal-article","created":{"date-parts":[[2017,3,31]],"date-time":"2017-03-31T03:33:22Z","timestamp":1490931202000},"page":"72-80","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Alterations of haemodynamic parameters in spontaneously hypertensive rats by A ristolochia ringens Vahl. (Aristolochiaceae)"],"prefix":"10.1016","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2353-1328","authenticated-orcid":false,"given":"Flora Ruth","family":"Aigbe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdul Sattar Zubaid","family":"Munavvar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassan","family":"Rathore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olorunfemi","family":"Eseyin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yen Pei","family":"Pei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Safia","family":"Akhtar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashfaq","family":"Chohan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Jin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jooli","family":"Khoo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samual","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed","family":"Lazhari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheryar","family":"Afzar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fiaz","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olufunmilayo Olaide","family":"Adeyemi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward","family":"Johns","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.jtcme.2017.02.006_bib1","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1161\/CIRCULATIONAHA.106.179918","article-title":"Heart disease and stroke statistics-2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee","volume":"115","author":"Rosamond","year":"2007","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.jtcme.2017.02.006_bib2","first-page":"S3","article-title":"High blood pressure and end-organ damage","volume":"14","author":"Cutler","year":"1996","journal-title":"J\u00a0Hypertens"},{"key":"10.1016\/j.jtcme.2017.02.006_bib3","series-title":"Oxford Textbook of Medicine","article-title":"Essential hypertension-definition, epidemiology and pathophysiology","author":"Williams","year":"2010"},{"issue":"3","key":"10.1016\/j.jtcme.2017.02.006_bib4","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1161\/01.CIR.101.3.329","article-title":"Essential hypertension. Part I: definition and etiology","volume":"101","author":"Carretero","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.jtcme.2017.02.006_bib5","doi-asserted-by":"crossref","first-page":"167","DOI":"10.2174\/1567269053202651","article-title":"New physiological targets within the kidney for antihypertensive therapy","volume":"2","author":"Evans","year":"2005","journal-title":"Drug Dev Rev Online"},{"issue":"3","key":"10.1016\/j.jtcme.2017.02.006_bib6","doi-asserted-by":"crossref","first-page":"S27","DOI":"10.1016\/S1098-3597(09)60016-8","article-title":"The management and treatment of hypertension","volume":"9","author":"Germino","year":"2009","journal-title":"Clin Cornerstone"},{"key":"10.1016\/j.jtcme.2017.02.006_bib7","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1039\/b401950d","article-title":"Terpenoids of Aristolochia and their biological activities","volume":"21","author":"Wu","year":"2004","journal-title":"Nat Prod Rep"},{"key":"10.1016\/j.jtcme.2017.02.006_bib8","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S2225-4110(16)30111-0","article-title":"Chemical constituents and pharmacology of the Aristolochia (m\u0103d\u014du ling) species","volume":"2","author":"Kuo","year":"2012","journal-title":"J\u00a0Tradit Complement Med"},{"key":"10.1016\/j.jtcme.2017.02.006_bib9","series-title":"Textbook of Medicinal Plants from Nigeria","author":"Odugbemi","year":"2008"},{"issue":"1","key":"10.1016\/j.jtcme.2017.02.006_bib10","first-page":"29","article-title":"The anti-diarrhoeal activity of the aqueous root extract of Aristolochia ringens Vahl. (Aristolochiaceae)","volume":"22","author":"Adeyemi","year":"2012","journal-title":"Nig Q J Hosp Med"},{"issue":"6","key":"10.1016\/j.jtcme.2017.02.006_bib11","first-page":"1885","article-title":"The aqueous root extract of Aristolochia ringens (Vahl.) Aristolochiaceae inhibits chemically-induced inflammation in rodents","volume":"27","author":"Aigbe","year":"2014","journal-title":"Pak J Pharm Sci"},{"key":"10.1016\/j.jtcme.2017.02.006_bib12","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.jtcme.2014.05.001","article-title":"Anticancer activity of Aristolochia ringens (Vahl.) [Aristolochiaceae]","volume":"5","author":"Akindele","year":"2015","journal-title":"J\u00a0Tradit Complement Med"},{"issue":"9","key":"10.1016\/j.jtcme.2017.02.006_bib13","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1093\/chromsci\/47.9.817","article-title":"Determination of the volatile and semi-volatile secondary metabolites, and aristolochic acids in Aristolochia ringens Vahl","volume":"47","author":"Stashenko","year":"2009","journal-title":"J\u00a0Chromatogr Sci"},{"key":"10.1016\/j.jtcme.2017.02.006_bib14","first-page":"855","article-title":"Chemical constituents and pharmacology of Aristolochia species","volume":"vol. 32","author":"Wu","year":"2005"},{"key":"10.1016\/j.jtcme.2017.02.006_bib15","doi-asserted-by":"crossref","first-page":"2387","DOI":"10.1016\/j.nimb.2008.03.016","article-title":"Accelerator-based analytical technique in the study of some anti-diabetic medicinal plants of Nigeria","volume":"266","author":"Olabanji","year":"2008","journal-title":"Nucl Instr Meth Phys Res"},{"key":"10.1016\/j.jtcme.2017.02.006_bib16","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1472-8206.2008.00565.x","article-title":"Antihypertensive effects of crude extracts from leaves of Echinodorus grandiflorus","volume":"22","author":"Lessa","year":"2008","journal-title":"Fundam Clin Pharmacol"},{"issue":"7","key":"10.1016\/j.jtcme.2017.02.006_bib17","doi-asserted-by":"crossref","first-page":"470","DOI":"10.3109\/10641963.2010.549273","article-title":"Blood pressure lowering effect of the extract of aerial parts of Capparis aphylla is mediated through endothelium-dependent and independent mechanisms","volume":"33","author":"Shah","year":"2011","journal-title":"Clin Exp Hypertens"},{"key":"10.1016\/j.jtcme.2017.02.006_bib18","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.foodchem.2006.07.038","article-title":"Total phenols, ascorbic acid, b-carotene and lycopene in Portuguese wild edible mushrooms and their antioxidant activities","volume":"103","author":"Barros","year":"2007","journal-title":"Food Chem"},{"key":"10.1016\/j.jtcme.2017.02.006_bib19","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/S0378-8741(00)00184-7","article-title":"Experimental diuretic effects of Rosmarinus officinalis and Centaurium erythraea","volume":"71","author":"Haloui","year":"2000","journal-title":"J\u00a0Ethnopharmacol"},{"key":"10.1016\/j.jtcme.2017.02.006_bib20","first-page":"400","article-title":"Isolation, antihypertensive activity and structure activity relationship of flavonoids from three medicinal plants","volume":"44B","author":"Ahmed","year":"2005","journal-title":"Indian J Chem"},{"issue":"1","key":"10.1016\/j.jtcme.2017.02.006_bib21","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s10616-013-9661-4","article-title":"Impact of tannic acid on blood pressure, oxidative stress and urinary parameters in L-NNA-induced hypertensive rats","volume":"67","author":"Turgut","year":"2015","journal-title":"Cytotechnology"},{"key":"10.1016\/j.jtcme.2017.02.006_bib22","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1186\/1472-6882-12-221","article-title":"Antioxidant activity, total phenolic and total flavonoid contents of whole plant extracts Torilis leptophylla L","volume":"12","author":"Saeed","year":"2012","journal-title":"BMC Complement Altern Med"},{"key":"10.1016\/j.jtcme.2017.02.006_bib23","doi-asserted-by":"crossref","first-page":"307","DOI":"10.5264\/eiyogakuzashi.44.307","article-title":"Studies on product of browning reaction prepared from glucose amine","volume":"44","author":"Oyatzu","year":"1986","journal-title":"Jpn J Nutr"},{"key":"10.1016\/j.jtcme.2017.02.006_bib24","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1038\/1811199a0","article-title":"Antioxidant determinations by the use of a stable free radical","volume":"26","author":"Blois","year":"1958","journal-title":"Nature"},{"key":"10.1016\/j.jtcme.2017.02.006_bib25","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.3390\/molecules17021797","article-title":"Phenolic compounds and antioxidant activities of Liriope muscari","volume":"17","author":"Li","year":"2012","journal-title":"Molecules"},{"issue":"4","key":"10.1016\/j.jtcme.2017.02.006_bib26","doi-asserted-by":"crossref","first-page":"275","DOI":"10.17221\/132\/2010-CJFS","article-title":"Antimicrobial and antioxidant properties of phenolic acids alkyl esters","volume":"28","author":"Merkl","year":"2010","journal-title":"Czech J Food Sci"},{"issue":"4","key":"10.1016\/j.jtcme.2017.02.006_bib27","doi-asserted-by":"crossref","first-page":"R1071","DOI":"10.1152\/ajpregu.90925.2008","article-title":"Quercetin increases brain and muscle mitochondrial biogenesis and exercise tolerance","volume":"296","author":"Davis","year":"2009","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.jtcme.2017.02.006_bib28","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/sj.bjp.0704064","article-title":"Antihypertensive effects of the flavonoid quercetin in spontaneously hypertensive rats","volume":"133","author":"Duarte","year":"2001","journal-title":"Br J Pharmacol"}],"container-title":["Journal of Traditional and Complementary Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2225411017300226?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2225411017300226?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,2]],"date-time":"2018-09-02T23:26:44Z","timestamp":1535930804000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2225411017300226"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["S2225411017300226"],"URL":"https:\/\/doi.org\/10.1016\/j.jtcme.2017.02.006","relation":{},"ISSN":["2225-4110"],"issn-type":[{"value":"2225-4110","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Alterations of haemodynamic parameters in spontaneously hypertensive rats by Aristolochia ringens Vahl. (Aristolochiaceae)","name":"articletitle","label":"Article Title"},{"value":"Journal of Traditional and Complementary Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtcme.2017.02.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Center for Food and Biomolecules, National Taiwan University. Production and hosting by Elsevier Taiwan LLC.","name":"copyright","label":"Copyright"}]}}