{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T04:07:23Z","timestamp":1767586043859,"version":"build-2065373602"},"reference-count":19,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,6,23]],"date-time":"2019-06-23T00:00:00Z","timestamp":1561248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Traditional and Complementary Medicine"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.jtcme.2019.06.004","type":"journal-article","created":{"date-parts":[[2019,7,9]],"date-time":"2019-07-09T06:04:47Z","timestamp":1562652287000},"page":"82-89","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Lipophilic and hydrophilic leaf extracts of Portulaca oleracea (Purslane) disrupts female sex hormones in albino rats (Rattus norvegicus)"],"prefix":"10.1016","volume":"11","author":[{"given":"Victoria C.","family":"Obinna","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hope D.","family":"Kagbo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel O.","family":"Agu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.jtcme.2019.06.004_bib1","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1017\/S0890037X00043128","article-title":"Common purslane (portulaca oleracea)","volume":"11","author":"Mitich","year":"1997","journal-title":"Weed Technol"},{"key":"10.1016\/j.jtcme.2019.06.004_bib2","first-page":"1","article-title":"Portulaca oleracea L.: a review of phytochemistry and pharmacological effects","volume":"2015","author":"Zhou","year":"2015","journal-title":"BioMed Res Int"},{"issue":"11","key":"10.1016\/j.jtcme.2019.06.004_bib3","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1080\/10286020802320590","article-title":"Portulene, a new diterpene from Portulaca oleracea L","volume":"10","author":"Elkhayat","year":"2008","journal-title":"J\u00a0Asian Nat Prod Res"},{"issue":"August","key":"10.1016\/j.jtcme.2019.06.004_bib4","first-page":"1","article-title":"The useful plants of west Tropical Africa","volume":"1","author":"Burkill","year":"1985","journal-title":"Book"},{"year":"1993","series-title":"Handbook of African Medicinal Plants","author":"Iwu","key":"10.1016\/j.jtcme.2019.06.004_bib5"},{"issue":"6","key":"10.1016\/j.jtcme.2019.06.004_bib6","doi-asserted-by":"crossref","first-page":"349","DOI":"10.7897\/2230-8407.06672","article-title":"Preliminary phytochemical screening, renal and haematological effects of portulaca oleracea (whole plant) in Swiss albino mice","volume":"6","author":"Shafi","year":"2015","journal-title":"Int Res J Pharm"},{"issue":"3","key":"10.1016\/j.jtcme.2019.06.004_bib7","first-page":"213","article-title":"Evaluation of the reproductive functions of Portulaca Oleracea extracts in female albino rats","volume":"13","author":"Oyedeji","year":"2010","journal-title":"Res J Pharmacol"},{"issue":"5","key":"10.1016\/j.jtcme.2019.06.004_bib8","first-page":"86","article-title":"Evaluation of portulaca oleracea l for anti-fertility effect in female albino rats","volume":"6","author":"Nayaka","year":"2014","journal-title":"Int J Pharm Pharm Sci"},{"issue":"4","key":"10.1016\/j.jtcme.2019.06.004_bib9","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/BF01234480","article-title":"A\u00a0new approach to practical acute toxicity testing","volume":"54","author":"Lorke","year":"1983","journal-title":"Arch Toxicol"},{"year":"2008","series-title":"Part 5: Preparation, Reading and Reporting of Vaginal Smears","key":"10.1016\/j.jtcme.2019.06.004_bib10"},{"issue":"3","key":"10.1016\/j.jtcme.2019.06.004_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.9734\/JAMMR\/2017\/33455","article-title":"Endocrine effect of Beta cypermethrin on female albino rats","volume":"23","author":"Obinna","year":"2017","journal-title":"J\u00a0Adv Med Med Res"},{"issue":"2","key":"10.1016\/j.jtcme.2019.06.004_bib12","first-page":"87","article-title":"Blood sample collection in small laboratory animals","volume":"1","author":"Parasuraman","year":"2010","journal-title":"J\u00a0Pharmacol Pharmacother"},{"year":"1965","series-title":"Histopathologic Technique and Practice Histochemistry","author":"Lillie","key":"10.1016\/j.jtcme.2019.06.004_bib13"},{"key":"10.1016\/j.jtcme.2019.06.004_bib14","series-title":"Animal Physiology","first-page":"373","article-title":"Reproduction","author":"Verma","year":"2015"},{"issue":"7","key":"10.1016\/j.jtcme.2019.06.004_bib15","first-page":"686","article-title":"Reproductive Technology in farm animals: new facets and findings: a Review","volume":"10","author":"Sejian","year":"2010","journal-title":"J\u00a0Biol Sci"},{"issue":"1","key":"10.1016\/j.jtcme.2019.06.004_bib16","doi-asserted-by":"crossref","first-page":"21","DOI":"10.5455\/ajpbp.20190124101830","article-title":"Effects of lipophilic and hydrophilic leaf extracts of Portulaca oleracea Linn . ( Purslane ) on male reproductive parameters in albino rats","volume":"9","author":"Obinna","year":"2019","journal-title":"Am J Physiol Biochem Pharmacol"},{"issue":"01","key":"10.1016\/j.jtcme.2019.06.004_bib17","doi-asserted-by":"crossref","first-page":"75","DOI":"10.30574\/gscbps.2019.7.1.0042","article-title":"Haematological profile of albino rats exposed to polar leaf extracts of Portulaca","volume":"07","author":"Obinna","year":"2019","journal-title":"GSC Biol Pharm Sci"},{"issue":"9","key":"10.1016\/j.jtcme.2019.06.004_bib18","doi-asserted-by":"crossref","first-page":"3436","DOI":"10.3382\/ps\/pex161","article-title":"The effects of phytosterols on the sexual behavior and reproductive function in the Japanese quail (Coturnix coturnix japonica)","volume":"96","author":"Qasimi","year":"2017","journal-title":"Poultry Sci"},{"issue":"3","key":"10.1016\/j.jtcme.2019.06.004_bib19","first-page":"205","article-title":"Effects of Portulaca oleracea ethanolic extract on reproductive system of aging female mice","volume":"14","author":"Ahangarpour","year":"2016","journal-title":"Int J Reprod Med"}],"container-title":["Journal of Traditional and Complementary Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S222541101831040X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S222541101831040X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T06:54:18Z","timestamp":1762412058000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S222541101831040X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["S222541101831040X"],"URL":"https:\/\/doi.org\/10.1016\/j.jtcme.2019.06.004","relation":{},"ISSN":["2225-4110"],"issn-type":[{"type":"print","value":"2225-4110"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lipophilic and hydrophilic leaf extracts of Portulaca oleracea (Purslane) disrupts female sex hormones in albino rats (Rattus norvegicus)","name":"articletitle","label":"Article Title"},{"value":"Journal of Traditional and Complementary Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtcme.2019.06.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Center for Food and Biomolecules, National Taiwan University. Production and hosting by Elsevier Taiwan LLC.","name":"copyright","label":"Copyright"}]}}