{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T11:01:05Z","timestamp":1788433265875,"version":"build-2803163510"},"reference-count":26,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T00:00:00Z","timestamp":1684800000000},"content-version":"vor","delay-in-days":629,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Transplantation and Cellular Therapy"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.jtct.2021.05.026","type":"journal-article","created":{"date-parts":[[2021,6,6]],"date-time":"2021-06-06T19:32:57Z","timestamp":1623007977000},"page":"769.e1-769.e8","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Infused Autograft Absolute Lymphocyte Count Predicts Superior Survival in Diffuse Large B Cell Lymphoma Patients Post-Autologous Peripheral Blood Hematopoietic Stem Cell Transplantation: A Matched Case-Control Study"],"prefix":"10.1016","volume":"27","author":[{"given":"Luis F.","family":"Porrata","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwin A.","family":"Burgstaler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey L.","family":"Winters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eapen","family":"Jacob","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Inwards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen M.","family":"Ansell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivana N.","family":"Micallef","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick B.","family":"Johnston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"Villasboas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonas","family":"Paludo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svetomir N.","family":"Markovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtct.2021.05.026_bib0001","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1182\/blood.V98.3.579","article-title":"Early lymphocyte count predicts superior survival after autologous hematopoietic stem cell transplantation in multiple myeloma or non-Hodgkin lymphoma","volume":"98","author":"Porrata","year":"2001","journal-title":"Blood"},{"key":"10.1016\/j.jtct.2021.05.026_bib0002","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/j.bbmt.2008.04.013","article-title":"Early lymphocyte recovery predicts superior survival after autologous peripheral hematopoietic stem cell transplantation in non-Hodgkin lymphoma: a prospective study","volume":"14","author":"Porrata","year":"2008","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.jtct.2021.05.026_bib0003","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.3109\/10428194.2015.1129537","article-title":"Early immune recovery after autologous transplantation in non-Hodgkin lymphoma patients; predictive factors and clinical significance","volume":"57","author":"Valtola","year":"2016","journal-title":"Leuk Lymphoma"},{"key":"10.1016\/j.jtct.2021.05.026_bib0004","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1038\/sj.bmt.1704355","article-title":"Infused peripheral blood autograft absolute lymphocyte count correlates with day 15 absolute lymphocyte count and clinical outcome after autologous peripheral hematopoietic stem cell transplantation in non-Hodgkin lymphoma","volume":"33","author":"Porrata","year":"2004","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.jtct.2021.05.026_bib0005","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1038\/sj.leu.2403341","article-title":"The dose of infused lymphocytes in the autograft directly correlates with clinical outcome and autologous peripheral blood hematopoietic stem cell transplantation in multiple myeloma","volume":"18","author":"Porrata","year":"2004","journal-title":"Leukemia"},{"key":"10.1016\/j.jtct.2021.05.026_bib0006","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.bbmt.2007.08.051","article-title":"Higher infused lymphocyte dose predicts higher lymphocyte recovery, which in turn, predicts superior overall survival following autologous hematopoietic stem cell transplantation for multiple myeloma","volume":"14","author":"Hiwase","year":"2008","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.jtct.2021.05.026_bib0007","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/j.bbmt.2016.01.024","article-title":"Immunologic autograft engineering and survival in non-Hodgkin lymphoma","volume":"22","author":"Porrata","year":"2016","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.jtct.2021.05.026_bib0008","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1093\/annonc\/mdx097","article-title":"International Working Group consensus response evaluation criteria in lymphoma (RECIL 2017)","volume":"28","author":"Younes","year":"2017","journal-title":"Ann Oncol"},{"key":"10.1016\/j.jtct.2021.05.026_bib0009","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1214\/aoap\/1177005436","article-title":"The average performance of the greedy matching algorithm","volume":"3","author":"Dyer","year":"1993","journal-title":"Ann Appl Probab"},{"key":"10.1016\/j.jtct.2021.05.026_bib0010","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1080\/01621459.1958.10501452","article-title":"Nonparametric estimation from incomplete observations","volume":"53","author":"Kaplan","year":"1958","journal-title":"J Am Stat Assoc"},{"key":"10.1016\/j.jtct.2021.05.026_bib0011","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.2517-6161.1972.tb00899.x","article-title":"Regression models and life-tables","volume":"34","author":"Cox","year":"1972","journal-title":"J R Stat Soc Series B Stat Methodol"},{"key":"10.1016\/j.jtct.2021.05.026_bib0012","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.bbmt.2014.03.007","article-title":"Lymphocyte subset recovery and outcome after autologous hematopoietic stem cell transplantation for plasma cell myeloma","volume":"20","author":"Rueff","year":"2014","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.jtct.2021.05.026_bib0013","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1080\/14653240802165665","article-title":"The role of stem cell mobilization regimen on lymphocyte collection yield in patients with multiple myeloma","volume":"10","author":"Hiwase","year":"2008","journal-title":"Cytotherapy"},{"key":"10.1016\/j.jtct.2021.05.026_bib0014","doi-asserted-by":"crossref","first-page":"315","DOI":"10.3816\/CLM.2007.n.009","article-title":"AMD3100 affects autograft lymphocyte collection and progression-free survival after autologous stem cell transplantation in non-Hodgkin lymphoma","volume":"7","author":"Holtan","year":"2007","journal-title":"Clin Lymphoma Myeloma"},{"key":"10.1016\/j.jtct.2021.05.026_bib0015","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1089\/107999099314054","article-title":"Expression of interleukin-10 in isolated CD8+ T cells and monocytes from growth factor-mobilized peripheral blood stem cell products: a mechanism of immune dysfunction","volume":"19","author":"Varney","year":"1999","journal-title":"J Interferon Cytokine Res"},{"key":"10.1016\/j.jtct.2021.05.026_bib0016","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1016\/S1567-5769(01)00062-5","article-title":"Activation-induced T-cell apoptosis by monocytes from stem cell products","volume":"1","author":"Ino","year":"2001","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.jtct.2021.05.026_bib0017","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1002\/ajh.24758","article-title":"Association between elevated pre-treatment serum cytokines and peripheral blood cellular markers of immunosuppression in patients with lymphoma","volume":"92","author":"Binder","year":"2017","journal-title":"Am J Hematol"},{"key":"10.1016\/j.jtct.2021.05.026_bib0018","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1038\/bmt.2017.225","article-title":"Infusion of autograft natural killer cell\/CD14 + HLA-DRDIM cell ratio predicts survival in lymphoma post-autologous stem cell transplantation","volume":"53","author":"Kansagra","year":"2018","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.jtct.2021.05.026_bib0019","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.leukres.2019.03.009","article-title":"Autograft immune content and survival in non-Hodgkin's lymphoma: a post hoc analysis","volume":"81","author":"Porrata","year":"2019","journal-title":"Leuk Res"},{"key":"10.1016\/j.jtct.2021.05.026_bib0020","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1080\/10428194.2020.1762879","article-title":"Autograft cellular composition and outcome in NHL patients: results of the prospective multicenter GOA study","volume":"61","author":"Turunen","year":"2020","journal-title":"Leuk Lymphoma"},{"key":"10.1016\/j.jtct.2021.05.026_bib0021","first-page":"583","article-title":"NK cell subgroups, phenotype, and functions after autologous stem cell transplantation","author":"Jacobs","year":"20156","journal-title":"Front Immunol"},{"key":"10.1016\/j.jtct.2021.05.026_bib0022","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1038\/sj.bmt.1703203","article-title":"Immunomodulation of early engrafted natural killer cells with interleukin-2 and interferon-alpha in autologous stem cell transplantation","volume":"28","author":"Porrata","year":"2001","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.jtct.2021.05.026_bib0023","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1097\/MOH.0000000000000384","article-title":"The importance of natural killer cell immunoglobulin-like receptor-mismatch in transplant outcomes","volume":"24","author":"Stringaris","year":"2017","journal-title":"Curr Opin Hematol"},{"key":"10.1016\/j.jtct.2021.05.026_bib0024","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtct.2020.10.023","article-title":"Early adaptive natural killer cell expansion is associated with decreased relapse after autologous transplantation for multiple myeloma","volume":"27","author":"Merino","year":"2021","journal-title":"Transplant Cell Ther"},{"key":"10.1016\/j.jtct.2021.05.026_bib0025","doi-asserted-by":"crossref","first-page":"e1792","DOI":"10.1038\/cddis.2015.162","article-title":"T-cell exhaustion in the tumor microenvironment","volume":"6","author":"Jiang","year":"2015","journal-title":"Cell Death Dis"},{"key":"10.1016\/j.jtct.2021.05.026_bib0026","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/5385972","article-title":"Autologous graft-versus-tumor effect: reality or fiction?","volume":"2016","author":"Porrata","year":"2016","journal-title":"Adv Hematol"}],"container-title":["Transplantation and Cellular Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666636721009453?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666636721009453?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T03:01:28Z","timestamp":1763002888000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666636721009453"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":26,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["S2666636721009453"],"URL":"https:\/\/doi.org\/10.1016\/j.jtct.2021.05.026","relation":{},"ISSN":["2666-6367"],"issn-type":[{"value":"2666-6367","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Infused Autograft Absolute Lymphocyte Count Predicts Superior Survival in Diffuse Large B Cell Lymphoma Patients Post-Autologous Peripheral Blood Hematopoietic Stem Cell Transplantation: A Matched Case-Control Study","name":"articletitle","label":"Article Title"},{"value":"Transplantation and Cellular Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtct.2021.05.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The American Society for Transplantation and Cellular Therapy. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}