{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T01:09:21Z","timestamp":1792372161586,"version":"4.4.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Transplantation and Cellular Therapy"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.jtct.2024.04.019","type":"journal-article","created":{"date-parts":[[2024,4,30]],"date-time":"2024-04-30T17:07:03Z","timestamp":1714496823000},"page":"685.e1-685.e12","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Impact of Early Cytomegalovirus Reactivation After Allogeneic Hematopoietic Stem Cell Transplantation on Relapse in Patients With Myelodysplastic Syndrome: A Nationwide Retrospective Study From Adult Myelodysplastic Syndrome Working Group of the JSTCT"],"prefix":"10.1016","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6203-9435","authenticated-orcid":false,"given":"Tatsuya","family":"Konishi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kensuke","family":"Matsuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1438-3623","authenticated-orcid":false,"given":"Hidehiro","family":"Itonaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8661-3179","authenticated-orcid":false,"given":"Noriko","family":"Doki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuya","family":"Nishida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken-ichi","family":"Matsuoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3976-5230","authenticated-orcid":false,"given":"Takashi","family":"Ikeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4866-9307","authenticated-orcid":false,"given":"Yoshinobu","family":"Kanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Fukuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6704-3633","authenticated-orcid":false,"given":"Junya","family":"Kanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirohisa","family":"Nakamae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0945-0513","authenticated-orcid":false,"given":"Kazunori","family":"Imada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasunori","family":"Ueda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0393-4066","authenticated-orcid":false,"given":"Tatsuo","family":"Ichinohe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4404-2870","authenticated-orcid":false,"given":"Yoshiko","family":"Atsuta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken","family":"Ishiyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"23","key":"10.1016\/j.jtct.2024.04.019_bib0001","doi-asserted-by":"crossref","first-page":"5711","DOI":"10.1182\/blood-2008-10-143560","article-title":"How we treat cytomegalovirus in hematopoietic cell transplant recipients","volume":"113","author":"Boeckh","year":"2009","journal-title":"Blood"},{"issue":"19","key":"10.1016\/j.jtct.2024.04.019_bib0002","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1182\/blood.2019000956","article-title":"How I treat CMV reactivation after allogeneic hematopoietic stem cell transplantation","volume":"135","author":"Einsele","year":"2020","journal-title":"Blood"},{"issue":"8","key":"10.1016\/j.jtct.2024.04.019_bib0003","doi-asserted-by":"crossref","first-page":"e260","DOI":"10.1016\/S1473-3099(19)30107-0","article-title":"Guidelines for the management of cytomegalovirus infection in patients with haematological malignancies and after stem cell transplantation from the 2017 European Conference on Infections in Leukaemia (ECIL 7)","volume":"19","author":"Ljungman","year":"2019","journal-title":"Lancet Infect Dis"},{"issue":"3","key":"10.1016\/j.jtct.2024.04.019_bib0004","doi-asserted-by":"crossref","first-page":"e119","DOI":"10.1016\/S2352-3026(15)00289-6","article-title":"Cytomegalovirus viral load and mortality after haemopoietic stem cell transplantation in the era of pre-emptive therapy: a retrospective cohort study","volume":"3","author":"Green","year":"2016","journal-title":"Lancet Haematol"},{"issue":"20","key":"10.1016\/j.jtct.2024.04.019_bib0005","doi-asserted-by":"crossref","first-page":"2427","DOI":"10.1182\/blood-2015-11-679639","article-title":"Early cytomegalovirus reactivation remains associated with increased transplant-related mortality in the current era: a CIBMTR analysis","volume":"127","author":"Teira","year":"2016","journal-title":"Blood"},{"issue":"3","key":"10.1016\/j.jtct.2024.04.019_bib0006","doi-asserted-by":"crossref","first-page":"e620","DOI":"10.1093\/cid\/ciaa1871","article-title":"Effect of cytomegalovirus reactivation with or without acute graft-versus-host disease on the risk of nonrelapse mortality","volume":"73","author":"Akahoshi","year":"2021","journal-title":"Clin Infect Dis"},{"issue":"12","key":"10.1016\/j.jtct.2024.04.019_bib0007","doi-asserted-by":"crossref","first-page":"3029","DOI":"10.1007\/s00277-021-04660-3","volume":"100","author":"Kimura","year":"2021","journal-title":"Ann Hematol"},{"issue":"8","key":"10.1016\/j.jtct.2024.04.019_bib0008","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1093\/cid\/ciz490","article-title":"A mortality analysis of letermovir prophylaxis for cytomegalovirus (CMV) in CMV-seropositive recipients of allogeneic hematopoietic cell transplantation","volume":"70","author":"Ljungman","year":"2020","journal-title":"Clin Infect Dis"},{"issue":"25","key":"10.1016\/j.jtct.2024.04.019_bib0009","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.1056\/NEJMoa1706640","article-title":"Letermovir prophylaxis for cytomegalovirus in hematopoietic-cell transplantation","volume":"377","author":"Marty","year":"2017","journal-title":"N Engl J Med"},{"issue":"11","key":"10.1016\/j.jtct.2024.04.019_bib0010","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1016\/j.bbmt.2017.07.025","article-title":"Cytomegalovirus reactivation is associated with increased risk of late-onset invasive fungal disease after allogeneic hematopoietic stem cell transplantation: a multicenter study in the current era of viral load monitoring","volume":"23","author":"Yong","year":"2017","journal-title":"Biol Blood Marrow Transplant"},{"issue":"5","key":"10.1016\/j.jtct.2024.04.019_bib0011","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1182\/blood-2010-08-304121","article-title":"Early human cytomegalovirus replication after transplantation is associated with a decreased relapse risk: evidence for a putative virus-versus-leukemia effect in acute myeloid leukemia patients","volume":"118","author":"Elmaagacli","year":"2011","journal-title":"Blood"},{"issue":"7","key":"10.1016\/j.jtct.2024.04.019_bib0012","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1182\/blood-2013-02-487074","article-title":"CMV reactivation after allogeneic HCT and relapse risk: evidence for early protection in acute myeloid leukemia","volume":"122","author":"Green","year":"2013","journal-title":"Blood"},{"issue":"11","key":"10.1016\/j.jtct.2024.04.019_bib0013","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.1016\/j.bbmt.2015.07.019","volume":"21","author":"Takenaka","year":"2015","journal-title":"Biol Blood Marrow Transplant"},{"issue":"11","key":"10.1016\/j.jtct.2024.04.019_bib0014","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1038\/s41409-018-0172-y","article-title":"Early human cytomegalovirus reactivation is associated with lower incidence of relapse of myeloproliferative disorders after allogeneic hematopoietic stem cell transplantation","volume":"53","author":"Peric","year":"2018","journal-title":"Bone Marrow Transpl"},{"issue":"1","key":"10.1016\/j.jtct.2024.04.019_bib0015","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1182\/bloodadvances.2021005509","article-title":"Impact of CMV reactivation on relapse of acute myeloid leukemia after HCT is dependent on disease stage and ATG","volume":"6","author":"Turki","year":"2022","journal-title":"Blood Adv"},{"issue":"12","key":"10.1016\/j.jtct.2024.04.019_bib0016","doi-asserted-by":"crossref","first-page":"2699","DOI":"10.1182\/bloodadvances.2022009376","article-title":"CMV reactivation after allogeneic HCT is associated with a reduced risk of relapse in acute lymphoblastic leukemia","volume":"7","author":"Akahoshi","year":"2023","journal-title":"Blood Adv"},{"issue":"10","key":"10.1016\/j.jtct.2024.04.019_bib0017","doi-asserted-by":"crossref","first-page":"2070","DOI":"10.1016\/j.bbmt.2019.06.008","article-title":"Early cytomegalovirus reactivation and expansion of CD56(bright)CD16(dim\/-)DNAM1(+) natural killer cells are associated with antileukemia effect after haploidentical stem cell transplantation in acute leukemia","volume":"25","author":"Jang","year":"2019","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.jtct.2024.04.019_bib0018","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.732826","article-title":"CMV infection and CMV-specific immune reconstitution following haploidentical stem cell transplantation: an update","volume":"12","author":"Luo","year":"2021","journal-title":"Front Immunol"},{"issue":"5","key":"10.1016\/j.jtct.2024.04.019_bib0019","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1038\/s41409-022-01603-y","article-title":"Adaptive NK cells undergo a dynamic modulation in response to human cytomegalovirus and recruit T cells in in vitro migration assays","volume":"57","author":"Bas\u00edlio-Queir\u00f3s","year":"2022","journal-title":"Bone Marrow Transpl"},{"issue":"1","key":"10.1016\/j.jtct.2024.04.019_bib0020","doi-asserted-by":"crossref","first-page":"2603","DOI":"10.1038\/s41467-022-29943-9","article-title":"Immunoprofiling reveals cell subsets associated with the trajectory of cytomegalovirus reactivation post stem cell transplantation","volume":"13","author":"Stern","year":"2022","journal-title":"Nat Commun"},{"issue":"1","key":"10.1016\/j.jtct.2024.04.019_bib0021","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s12185-015-1894-x","article-title":"Introduction of Transplant Registry Unified Management Program 2 (TRUMP2): scripts for TRUMP data analyses, part I (variables other than HLA-related data)","volume":"103","author":"Atsuta","year":"2016","journal-title":"Int J Hematol"},{"issue":"1","key":"10.1016\/j.jtct.2024.04.019_bib0022","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s12185-015-1907-9","article-title":"Scripts for TRUMP data analyses. Part II (HLA-related data): statistical analyses specific for hematopoietic stem cell transplantation","volume":"103","author":"Kanda","year":"2016","journal-title":"Int J Hematol"},{"issue":"6","key":"10.1016\/j.jtct.2024.04.019_bib0023","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1182\/blood.V89.6.2079","article-title":"International scoring system for evaluating prognosis in myelodysplastic syndromes","volume":"89","author":"Greenberg","year":"1997","journal-title":"Blood"},{"issue":"8","key":"10.1016\/j.jtct.2024.04.019_bib0024","doi-asserted-by":"crossref","first-page":"2912","DOI":"10.1182\/blood-2005-05-2004","article-title":"Hematopoietic cell transplantation (HCT)-specific comorbidity index: a new tool for risk assessment before allogeneic HCT","volume":"106","author":"Sorror","year":"2005","journal-title":"Blood"},{"issue":"3","key":"10.1016\/j.jtct.2024.04.019_bib0025","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.bbmt.2008.12.497","article-title":"Reduced-intensity conditioning regimen workshop: defining the dose spectrum. Report of a workshop convened by the Center for International Blood and Marrow Transplant Research","volume":"15","author":"Giralt","year":"2009","journal-title":"Biol Blood Marrow Transplant"},{"issue":"3","key":"10.1016\/j.jtct.2024.04.019_bib0026","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.bbmt.2014.12.001","article-title":"National Institutes of Health Consensus Development Project on criteria for clinical trials in chronic graft-versus-host disease: I. The 2014 Diagnosis and Staging Working Group report","volume":"21","author":"Jagasia","year":"2015","journal-title":"Biol Blood Marrow Transplant"},{"issue":"3","key":"10.1016\/j.jtct.2024.04.019_bib0027","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/bmt.2012.244","article-title":"Investigation of the freely available easy-to-use software 'EZR' for medical statistics","volume":"48","author":"Kanda","year":"2013","journal-title":"Bone Marrow Transpl"},{"issue":"3","key":"10.1016\/j.jtct.2024.04.019_bib0028","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1086\/338624","article-title":"High risk of death due to bacterial and fungal infection among cytomegalovirus (CMV)-seronegative recipients of stem cell transplants from seropositive donors: evidence for indirect effects of primary CMV infection","volume":"185","author":"Nichols","year":"2002","journal-title":"J Infect Dis"},{"issue":"9","key":"10.1016\/j.jtct.2024.04.019_bib0029","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/j.bbmt.2010.03.020","article-title":"Evidence for a bidirectional relationship between cytomegalovirus replication and acute graft-versus-host disease","volume":"16","author":"Cantoni","year":"2010","journal-title":"Biol Blood Marrow Transplant"},{"issue":"17","key":"10.1016\/j.jtct.2024.04.019_bib0030","doi-asserted-by":"crossref","first-page":"eaax9856","DOI":"10.1126\/sciadv.aax9856","article-title":"Linking indirect effects of cytomegalovirus in transplantation to modulation of monocyte innate immune function","volume":"6","author":"Sen","year":"2020","journal-title":"Sci Adv"},{"issue":"6","key":"10.1016\/j.jtct.2024.04.019_bib0031","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1182\/bloodadvances.2019000814","article-title":"Heterogeneous impact of cytomegalovirus reactivation on nonrelapse mortality in hematopoietic stem cell transplantation","volume":"4","author":"Kaito","year":"2020","journal-title":"Blood Adv"},{"issue":"3","key":"10.1016\/j.jtct.2024.04.019_bib0032","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1111\/ajt.15642","article-title":"Optimizing anti-T-lymphocyte globulin dosing to improve long-term outcome after unrelated hematopoietic cell transplantation for hematologic malignancies","volume":"20","author":"Turki","year":"2020","journal-title":"Am J Transplant"},{"issue":"25","key":"10.1016\/j.jtct.2024.04.019_bib0033","doi-asserted-by":"crossref","first-page":"3835","DOI":"10.1182\/blood-2015-03-631853","article-title":"CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCR\u03b2 repertoire","volume":"125","author":"Suessmuth","year":"2015","journal-title":"Blood"},{"issue":"26","key":"10.1016\/j.jtct.2024.04.019_bib0034","doi-asserted-by":"crossref","first-page":"2874","DOI":"10.1182\/blood.2020009492","article-title":"CMV exposure drives long-term CD57+ CD4 memory T-cell inflation following allogeneic stem cell transplant","volume":"138","author":"Yeh","year":"2021","journal-title":"Blood"},{"issue":"6","key":"10.1016\/j.jtct.2024.04.019_bib0035","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1038\/leu.2012.374","article-title":"\u03b3\u03b4T cells elicited by CMV reactivation after allo-SCT cross-recognize CMV and leukemia","volume":"27","author":"Scheper","year":"2013","journal-title":"Leukemia"},{"issue":"7","key":"10.1016\/j.jtct.2024.04.019_bib0036","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1038\/sj.bmt.1703513","article-title":"Monitoring of cytomegalovirus reactivation after allogeneic stem cell transplantation: comparison of an antigenemia assay and quantitative real-time polymerase chain reaction","volume":"29","author":"Yakushiji","year":"2002","journal-title":"Bone Marrow Transplant"}],"container-title":["Transplantation and Cellular Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666636724003725?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666636724003725?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T11:16:49Z","timestamp":1751368609000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666636724003725"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":36,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["S2666636724003725"],"URL":"https:\/\/doi.org\/10.1016\/j.jtct.2024.04.019","relation":{},"ISSN":["2666-6367"],"issn-type":[{"value":"2666-6367","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of Early Cytomegalovirus Reactivation After Allogeneic Hematopoietic Stem Cell Transplantation on Relapse in Patients With Myelodysplastic Syndrome: A Nationwide Retrospective Study From Adult Myelodysplastic Syndrome Working Group of the JSTCT","name":"articletitle","label":"Article Title"},{"value":"Transplantation and Cellular Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtct.2024.04.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The American Society for Transplantation and Cellular Therapy. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}