{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T22:27:52Z","timestamp":1791498472077,"version":"4.3.4"},"reference-count":36,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Transplantation and Cellular Therapy"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.jtct.2024.06.015","type":"journal-article","created":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T20:53:07Z","timestamp":1718311987000},"page":"903.e1-903.e9","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Impact of Graft-Versus-Host Disease on Relapse and Nonrelapse Mortality Following Posttransplant Cyclophosphamide-Based Transplantation"],"prefix":"10.1016","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2061-8126","authenticated-orcid":false,"given":"Scott R.","family":"Solomon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lizamarie","family":"Bachier-Rodriguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asad","family":"Bashey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2707-8927","authenticated-orcid":false,"given":"Xu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katelin C.","family":"Jackson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. Kent","family":"Holland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence E.","family":"Morris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melhem M.","family":"Solh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.jtct.2024.06.015_bib0001","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1038\/sj.bmt.1701510","article-title":"A randomised, prospective comparison of allogeneic bone marrow and peripheral blood progenitor cell transplantation in the treatment of haematological malignancies","volume":"22","author":"Vigorito","year":"1998","journal-title":"Bone Marrow Transplantat"},{"issue":"3","key":"10.1016\/j.jtct.2024.06.015_bib0002","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1200\/JCO.2000.18.3.537","article-title":"Randomized trial of bone marrow versus lenograstim-primed blood cell allogeneic transplantation in patients with early-stage leukemia: a report from the Societe Francaise de Greffe de Moelle","volume":"18","author":"Blaise","year":"2000","journal-title":"J Clin Oncol"},{"issue":"9","key":"10.1016\/j.jtct.2024.06.015_bib0003","doi-asserted-by":"crossref","first-page":"3128","DOI":"10.1182\/blood.V100.9.3128","article-title":"Chronic graft-versus-host disease after allogeneic blood stem cell transplantation: long-term results of a randomized study","volume":"100","author":"Mohty","year":"2002","journal-title":"Blood"},{"issue":"25","key":"10.1016\/j.jtct.2024.06.015_bib0004","doi-asserted-by":"crossref","first-page":"2338","DOI":"10.1056\/NEJMoa2215943","article-title":"Post-transplantation cyclophosphamide-based graft-versus-host disease prophylaxis","volume":"388","author":"Bola\u00f1os-Meade","year":"2023","journal-title":"N Engl J Med"},{"issue":"25","key":"10.1016\/j.jtct.2024.06.015_bib0005","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1056\/NEJM198106183042507","article-title":"Antileukemic effect of chronic graft-versus-host disease","volume":"304","author":"Weiden","year":"1981","journal-title":"N Engl J Med"},{"issue":"6","key":"10.1016\/j.jtct.2024.06.015_bib0006","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1182\/blood.V73.6.1720.1720","article-title":"Influence of acute and chronic graft-versus-host disease on relapse and survival after bone marrow transplantation from HLA-identical siblings as treatment of acute and chronic leukemia","volume":"73","author":"Sullivan","year":"1989","journal-title":"Blood"},{"issue":"3","key":"10.1016\/j.jtct.2024.06.015_bib0007","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1182\/blood.V75.3.555.555","article-title":"Graft-versus-leukemia reactions after bone marrow transplantation","volume":"75","author":"Horowitz","year":"1990","journal-title":"Blood"},{"issue":"1-2","key":"10.1016\/j.jtct.2024.06.015_bib0008","doi-asserted-by":"crossref","first-page":"71","DOI":"10.3109\/10428199609045715","article-title":"The highest leukaemia-free survival after allogeneic bone marrow transplantation is seen in patients with grade I acute graft-versus-host disease. Acute and Chronic Leukaemia Working Parties of the European Group for Blood and Marrow Transplantation (EBMT)","volume":"24","author":"Ringd\u00e9n","year":"1996","journal-title":"Leuk Lymphoma"},{"issue":"6","key":"10.1016\/j.jtct.2024.06.015_bib0009","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1080\/146532400539369","article-title":"An analysis of the effect of chronic GvHD on relapse and survival following allogeneic PBSC transplantation","volume":"2","author":"Miflin","year":"2000","journal-title":"Cytotherapy"},{"issue":"11","key":"10.1016\/j.jtct.2024.06.015_bib0010","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1016\/j.bbmt.2012.06.014","article-title":"Graft-versus-host disease induced graft-versus-leukemia effect: greater impact on relapse and disease-free survival after reduced intensity conditioning","volume":"18","author":"Weisdorf","year":"2012","journal-title":"Biol Blood Marrow Transplantat"},{"issue":"1","key":"10.1016\/j.jtct.2024.06.015_bib0011","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1038\/s41409-018-0221-6","article-title":"Impact of graft-versus-host disease on relapse and survival after allogeneic stem cell transplantation for pediatric leukemia","volume":"54","author":"Kato","year":"2019","journal-title":"Bone Marrow Transplant"},{"issue":"10","key":"10.1016\/j.jtct.2024.06.015_bib0012","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1200\/JCO.2012.44.3523","article-title":"T-cell-replete HLA-haploidentical hematopoietic transplantation for hematologic malignancies using post-transplantation cyclophosphamide results in outcomes equivalent to those of contemporaneous HLA-matched related and unrelated donor transplantation","volume":"31","author":"Bashey","year":"2013","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jtct.2024.06.015_bib0013","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/8868142","article-title":"A phase II trial of melphalan based reduced-intensity conditioning for transplantation of T-replete HLA-haploidentical peripheral blood stem cells with posttransplant cyclophosphamide in patients with hematologic malignancies","volume":"2021","author":"Solh","year":"2021","journal-title":"Adv Hematol"},{"issue":"12","key":"10.1016\/j.jtct.2024.06.015_bib0014","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.1016\/j.bbmt.2012.06.019","volume":"18","author":"Solomon","year":"2012","journal-title":"Biol Blood Marrow Transplant"},{"issue":"7","key":"10.1016\/j.jtct.2024.06.015_bib0015","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1016\/j.bbmt.2015.03.003","article-title":"Total body irradiation-based myeloablative haploidentical stem cell transplantation is a safe and effective alternative to unrelated donor transplantation in patients without matched sibling donors","volume":"21","author":"Solomon","year":"2015","journal-title":"Biol Blood Marrow Transplant"},{"issue":"6","key":"10.1016\/j.jtct.2024.06.015_bib0016","first-page":"825","article-title":"1994 consensus conference on acute GVHD grading","volume":"15","author":"Przepiorka","year":"1995","journal-title":"Bone Marrow Transplant"},{"issue":"12","key":"10.1016\/j.jtct.2024.06.015_bib0017","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/j.bbmt.2005.09.004","article-title":"National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: I. Diagnosis and staging working group report","volume":"11","author":"Filipovich","year":"2005","journal-title":"Biol Blood Marrow Transplant"},{"issue":"3","key":"10.1016\/j.jtct.2024.06.015_bib0018","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.bbmt.2014.12.001","article-title":"National Institutes of Health Consensus Development project on criteria for clinical trials in chronic graft-versus-host disease: I. The 2014 Diagnosis and Staging Working Group report","volume":"21","author":"Jagasia","year":"2015","journal-title":"Biol Blood Marrow Transplantat"},{"issue":"11","key":"10.1016\/j.jtct.2024.06.015_bib0019","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1038\/sj.bmt.1703271","article-title":"Statistical methods for the analysis and presentation of the results of bone marrow transplants. Part 2: regression modeling","volume":"28","author":"Klein","year":"2001","journal-title":"Bone Marrow Transplant"},{"issue":"7","key":"10.1016\/j.jtct.2024.06.015_bib0020","doi-asserted-by":"crossref","first-page":"1980","DOI":"10.1182\/blood.V83.7.1980.1980","article-title":"Effect of T-cell depletion as graft-versus-host disease prophylaxis on engraftment, relapse, and disease-free survival in unrelated marrow transplantation for chronic myelogenous leukemia","volume":"83","author":"Drobyski","year":"1994","journal-title":"Blood"},{"issue":"9487","key":"10.1016\/j.jtct.2024.06.015_bib0021","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/S0140-6736(05)66996-6","article-title":"Effect of graft-versus-host disease prophylaxis on 3-year disease-free survival in recipients of unrelated donor bone marrow (T-cell Depletion Trial): a multi-centre, randomised phase II-III trial","volume":"366","author":"Wagner","year":"2005","journal-title":"Lancet"},{"issue":"12","key":"10.1016\/j.jtct.2024.06.015_bib0022","doi-asserted-by":"crossref","first-page":"2462","DOI":"10.1038\/leu.2012.135","article-title":"Impact of graft-versus-host disease after reduced-intensity conditioning allogeneic stem cell transplantation for acute myeloid leukemia: a report from the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation","volume":"26","author":"Baron","year":"2012","journal-title":"Leukemia"},{"issue":"4","key":"10.1016\/j.jtct.2024.06.015_bib0023","doi-asserted-by":"crossref","first-page":"E368","DOI":"10.1111\/ctr.12131","article-title":"A high antithymocyte globulin dose increases the risk of relapse after reduced intensity conditioning HSCT with unrelated donors","volume":"27","author":"Remberger","year":"2013","journal-title":"Clin Transplant"},{"issue":"5","key":"10.1016\/j.jtct.2024.06.015_bib0024","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1038\/s41409-022-01620-x","article-title":"Impact of in vivo T-cell depletion in patients with myelodysplastic syndromes undergoing allogeneic hematopoietic stem cell transplant: a registry study from the Chronic Malignancies Working Party of the EBMT","volume":"57","author":"Forcade","year":"2022","journal-title":"Bone Marrow Transplant"},{"issue":"9211","key":"10.1016\/j.jtct.2024.06.015_bib0025","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/S0140-6736(00)02090-0","article-title":"Allogeneic blood and bone-marrow stem-cell transplantation in haematological malignant diseases: a randomised trial","volume":"355","author":"Powles","year":"2000","journal-title":"Lancet"},{"issue":"11","key":"10.1016\/j.jtct.2024.06.015_bib0026","doi-asserted-by":"crossref","first-page":"2675","DOI":"10.1182\/blood-2011-12-396275","article-title":"Long-term outcomes after transplantation of HLA-identical related G-CSF-mobilized peripheral blood mononuclear cells versus bone marrow","volume":"119","author":"Mielcarek","year":"2012","journal-title":"Blood"},{"issue":"2","key":"10.1016\/j.jtct.2024.06.015_bib0027","doi-asserted-by":"crossref","first-page":"256","DOI":"10.3324\/haematol.2015.135699","article-title":"Peripheral blood stem cell graft compared to bone marrow after reduced intensity conditioning regimens for acute leukemia: a report from the ALWP of the EBMT","volume":"101","author":"Savani","year":"2016","journal-title":"Haematologica"},{"issue":"26","key":"10.1016\/j.jtct.2024.06.015_bib0028","doi-asserted-by":"crossref","first-page":"3002","DOI":"10.1200\/JCO.2017.72.8428","article-title":"Mobilized peripheral blood stem cells versus unstimulated bone marrow as a graft source for T-cell-replete haploidentical donor transplantation using post-transplant cyclophosphamide","volume":"35","author":"Bashey","year":"2017","journal-title":"J Clin Oncol"},{"issue":"1","key":"10.1016\/j.jtct.2024.06.015_bib0029","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s13045-023-01515-4","article-title":"Bone marrow graft versus peripheral blood graft in haploidentical hematopoietic stem cells transplantation: a retrospective analysis in1344 patients of SFGM-TC registry","volume":"17","author":"Lacan","year":"2024","journal-title":"J Hematol Oncol"},{"issue":"1","key":"10.1016\/j.jtct.2024.06.015_bib0030","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s13045-023-01403-x","article-title":"GVHD occurrence does not reduce AML relapse following PTCy-based haploidentical transplantation: a study from the ALWP of the EBMT","volume":"16","author":"Baron","year":"2023","journal-title":"J Hematol Oncol"},{"issue":"6","key":"10.1016\/j.jtct.2024.06.015_bib0031","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtct.2023.03.001","article-title":"Effect of graft-versus-host disease on post-transplantation outcomes following single cord blood transplantation compared with haploidentical transplantation with post-transplantation cyclophosphamide for adult acute myeloid leukemia","volume":"29","author":"Konuma","year":"2023","journal-title":"Transplant Cell Ther"},{"issue":"1","key":"10.1016\/j.jtct.2024.06.015_bib0032","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1038\/s41409-023-02142-w","article-title":"Effect of graft-versus-host disease on outcomes of HLA-haploidentical peripheral blood transplantation using post-transplant cyclophophamide","volume":"59","author":"Shimomura","year":"2024","journal-title":"Bone Marrow Transplantat"},{"key":"10.1016\/j.jtct.2024.06.015_bib0033","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fimmu.2022.796349","article-title":"Post-transplantation cyclophosphamide uniquely restrains alloreactive CD4+ T-cell proliferation and differentiation after murine mhc-haploidentical hematopoietic cell transplantation","volume":"13","author":"Hadjis","year":"2022","journal-title":"Front Immunol"},{"issue":"2","key":"10.1016\/j.jtct.2024.06.015_bib0034","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.bbmt.2017.10.023","article-title":"Grade II Acute graft-versus-host disease and higher nucleated cell graft dose improve progression-free survival after HLA-haploidentical transplant with post-transplant cyclophosphamide","volume":"24","author":"McCurdy","year":"2018","journal-title":"Biol Blood Marrow Transplant"},{"issue":"4","key":"10.1016\/j.jtct.2024.06.015_bib0035","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1080\/0284186X.2020.1837947","article-title":"Grade 2 acute GVHD is a factor of good prognosis in patients receiving peripheral blood stem cells haplo-transplant with post-transplant cyclophosphamide","volume":"60","author":"Chevallier","year":"2021","journal-title":"Acta Oncol"},{"issue":"11","key":"10.1016\/j.jtct.2024.06.015_bib0036","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1038\/leu.2014.145","article-title":"Sensitivity of hematological malignancies to graft-versus-host effects: an EBMT megafile analysis","volume":"28","author":"Stern","year":"2014","journal-title":"Leukemia"}],"container-title":["Transplantation and Cellular Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S266663672400472X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S266663672400472X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T03:59:55Z","timestamp":1756699195000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S266663672400472X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":36,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["S266663672400472X"],"URL":"https:\/\/doi.org\/10.1016\/j.jtct.2024.06.015","relation":{},"ISSN":["2666-6367"],"issn-type":[{"value":"2666-6367","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of Graft-Versus-Host Disease on Relapse and Nonrelapse Mortality Following Posttransplant Cyclophosphamide-Based Transplantation","name":"articletitle","label":"Article Title"},{"value":"Transplantation and Cellular Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtct.2024.06.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The American Society for Transplantation and Cellular Therapy. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}