{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T08:40:55Z","timestamp":1792658455298,"version":"4.5.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,7,6]],"date-time":"2016-07-06T00:00:00Z","timestamp":1467763200000},"content-version":"vor","delay-in-days":4204,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100008732","name":"Uehara Memorial Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008732","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["KO8 HL04484"],"award-info":[{"award-number":["KO8 HL04484"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HL60900"],"award-info":[{"award-number":["HL60900"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jtcvsonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Thoracic and Cardiovascular Surgery"],"published-print":{"date-parts":[[2005,1]]},"DOI":"10.1016\/j.jtcvs.2004.04.014","type":"journal-article","created":{"date-parts":[[2004,12,28]],"date-time":"2004-12-28T18:59:44Z","timestamp":1104260384000},"page":"129-137","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Influence of ischemic injury on vein graft remodeling: Role of cyclic adenosine monophosphate second messenger pathway in enhanced vein graft preservation"],"prefix":"10.25013","volume":"129","author":[{"given":"Taichi","family":"Sakaguchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomohiro","family":"Asai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dmitri","family":"Belov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morihito","family":"Okada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Pinsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann Marie","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshifumi","family":"Naka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtcvs.2004.04.014_BIB1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S1078-5884(05)80218-7","article-title":"Pathophysiology of vein graft failure","volume":"9","author":"Davies","year":"1995","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB2","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1161\/01.CIR.97.9.916","article-title":"Aortocoronary saphenous vein graft disease","volume":"97","author":"Motwani","year":"1998","journal-title":"Circulation"},{"issue":"suppl 1","key":"10.1016\/j.jtcvs.2004.04.014_BIB3","doi-asserted-by":"crossref","first-page":"S55","DOI":"10.1016\/S0167-5273(97)00214-3","article-title":"Towards the prevention of vein graft failure","volume":"62","author":"Mehta","year":"1997","journal-title":"Int J Cardiol"},{"issue":"suppl","key":"10.1016\/j.jtcvs.2004.04.014_BIB4","doi-asserted-by":"crossref","first-page":"S2245","DOI":"10.1016\/S0003-4975(01)03272-6","article-title":"The coronary artery bypass conduit","volume":"72","author":"Thatte","year":"2001","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB5","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1006\/excr.1994.1171","article-title":"Hypoxia stimulates human endothelial cells to release smooth muscle cell mitogens","volume":"213","author":"Michiels","year":"1994","journal-title":"Exp Cell Res"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB6","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1016\/S0003-4975(02)03425-2","article-title":"Improved patency in vein grafts harvested with surrounding tissue","volume":"73","author":"Souza","year":"2002","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB7","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/S0022-5223(03)00075-8","article-title":"Activation of mitogen-activated protein kinases during preparation of vein grafts and modulation by a synthetic inhibitor","volume":"126","author":"Bizekis","year":"2003","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB8","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0003-4975(03)00433-8","article-title":"Pressure distention stimulates the expression of endothelial adhesion molecules in the human saphenous vein graft","volume":"76","author":"Chello","year":"2003","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB9","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1006\/scel.1995.0038","article-title":"Hypoxia and modification of the endothelium","volume":"6","author":"Pinsky","year":"1995","journal-title":"Semin Cell Biol"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0167-4889(00)00041-0","article-title":"Endothelial cell responses to hypoxia","volume":"1497","author":"Michiels","year":"2000","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB11","doi-asserted-by":"crossref","first-page":"C546","DOI":"10.1152\/ajpcell.1992.262.3.C546","article-title":"Hypoxia-induced increased permeability of endothelial monolayers occurs through lowering of cellular cAMP levels","volume":"262","author":"Ogawa","year":"1992","journal-title":"Am J Physiol"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB12","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1161\/01.RES.79.4.773","article-title":"cAMP-mediated vascular protection in an orthotopic rat lung transplant model. Insights into the mechanism of action of prostaglandin E1 to improve lung preservation","volume":"79","author":"Naka","year":"1996","journal-title":"Circ Res"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB13","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0022-5223(99)70152-2","article-title":"Superior protection in orthotopic rat lung transplantation with cyclic adenosine monophosphate and nitroglycerin-containing preservation solution","volume":"118","author":"Kayano","year":"1999","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB14","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0022-4804(02)00038-0","article-title":"Cyclic AMP inhibits production of interleukin-6 and migration in human vascular smooth muscle cells","volume":"109","author":"Newman","year":"2003","journal-title":"J Surg Res"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB15","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1161\/01.RES.84.8.883","article-title":"Plasminogen is not required for neointima formation in a mouse model of vein graft stenosis","volume":"84","author":"Shi","year":"1999","journal-title":"Circ Res"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB16","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1161\/01.RES.86.9.982","article-title":"cAMP pulse during preservation inhibits the late development of cardiac isograft and allograft vasculopathy","volume":"86","author":"Wang","year":"2000","journal-title":"Circ Res"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB17","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1161\/01.RES.86.4.434","article-title":"Reduced neointima hyperplasia of vein bypass grafts in intercellular adhesion molecule-1-deficient mice","volume":"86","author":"Zou","year":"2000","journal-title":"Circ Res"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB18","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1161\/01.ATV.20.2.343","article-title":"Mouse model of transplant arteriosclerosis","volume":"20","author":"Dietrich","year":"2000","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB19","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1006\/jsre.1996.0380","article-title":"Influence of perioperative catheter injury on the long-term vein graft function and morphology","volume":"66","author":"Davies","year":"1996","journal-title":"J Surg Res"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB20","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/S1078-5884(98)80030-0","article-title":"Local effects of nitric oxide supplementation and suppression in the development of intimal hyperplasia in experimental vein grafts","volume":"15","author":"Fulton","year":"1998","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB21","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/S0039-6060(97)90184-7","article-title":"Short-term preservation of autogenous vein grafts","volume":"121","author":"Cavallari","year":"1997","journal-title":"Surgery"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB22","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/S0003-4975(02)04705-7","article-title":"Multi-photon microscopic evaluation of saphenous vein endothelium and its preservation with a new solution, GALA","volume":"75","author":"Tatte","year":"2003","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB23","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1172\/JCI119461","article-title":"Circumferential deformation and shear stress induce differential responses in saphenous vein endothelium exposed to arterial flow","volume":"99","author":"Golledge","year":"1997","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB24","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1161\/01.CIR.99.8.1047","article-title":"Arterial flow conditions downregulate thrombomodulin on saphenous vein endothelium","volume":"99","author":"Gosling","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB25","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0021-9150(98)00183-X","article-title":"Nitric oxide, prostacyclin and cyclic nucleotide formation in externally stented porcine vein grafts","volume":"141","author":"Jeremy","year":"1998","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB26","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/S0735-1097(00)00679-3","article-title":"8-chloro-cAMP inhibits smooth muscle cell proliferation in vitro and neointima formation induced by balloon injury in vivo","volume":"36","author":"Indolfi","year":"2000","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB27","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1161\/01.RES.88.3.319","article-title":"Membrane-bound protein kinase A inhibits smooth muscle cell proliferation in vitro and in vivo by amplifying cAMP-protein kinase A signals","volume":"88","author":"Indolfi","year":"2001","journal-title":"Circ Res"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB28","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/S0898-6568(99)00020-0","article-title":"Crosstalk between protein kinase A and growth factor receptor signaling pathways in arterial smooth muscle","volume":"11","author":"Bornfeldt","year":"1999","journal-title":"Cell Signal"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB29","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/S1078-5884(97)80054-8","article-title":"The influence of surgical preparation on cyclic nucleotide synthesis in an organ culture of human saphenous vein","volume":"13","author":"Jeremy","year":"1997","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB30","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/S0003-4975(96)01144-7","article-title":"Nitric oxide synthase and adenylyl and guanylyl cyclase activity in porcine interposition vein grafts","volume":"63","author":"Jeremy","year":"1997","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB31","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1016\/S0022-5223(02)73241-8","article-title":"Radial artery patency and clinical outcomes","volume":"125","author":"Buxton","year":"2003","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB32","doi-asserted-by":"crossref","first-page":"2028","DOI":"10.1074\/jbc.271.34.20828","article-title":"Elevated cyclic AMP inhibits NF-kappaB-mediated transcription in human monocytic cells and endothelial cells","volume":"271","author":"Ollivier","year":"1996","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB33","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1016\/S0021-9258(17)32442-0","article-title":"Signal transduction and gene regulation","volume":"269","author":"Lalli","year":"1994","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB34","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1097\/00004647-200004000-00006","article-title":"Cyclic adenosine monophosphate regulates the expression of the intercellular adhesion molecule and the inducible nitric oxide synthase in brain endothelial cells","volume":"20","author":"Balyasnikova","year":"2000","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB35","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1161\/01.ATV.17.8.1614","article-title":"Monocyte chemotactic protein-1 expression is associated with the development of vein graft intimal hyperplasia","volume":"17","author":"Stark","year":"1997","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB36","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0021-9150(99)00357-3","article-title":"Expression of intercellular adhesion molecules in human saphenous veins","volume":"150","author":"Crook","year":"2000","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB37","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/S1010-7940(99)00128-1","article-title":"Membrane stabilization in harvested vein graft storage","volume":"16","author":"Vural","year":"1999","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB38","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/S0002-9440(10)64576-2","article-title":"Rapid development of vein graft atheroma in ApoE-deficient mice","volume":"157","author":"Dietrich","year":"2000","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jtcvs.2004.04.014_BIB39","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1016\/S0002-9440(10)65675-1","article-title":"Mouse model of venous bypass graft arteriosclerosis","volume":"153","author":"Zou","year":"1998","journal-title":"Am J Pathol"}],"container-title":["The Journal of Thoracic and Cardiovascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022522304006397?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022522304006397?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T02:12:45Z","timestamp":1778638365000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022522304006397"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,1]]}},"alternative-id":["S0022522304006397"],"URL":"https:\/\/doi.org\/10.1016\/j.jtcvs.2004.04.014","relation":{},"ISSN":["0022-5223"],"issn-type":[{"value":"0022-5223","type":"print"}],"subject":[],"published":{"date-parts":[[2005,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Influence of ischemic injury on vein graft remodeling: Role of cyclic adenosine monophosphate second messenger pathway in enhanced vein graft preservation","name":"articletitle","label":"Article Title"},{"value":"The Journal of Thoracic and Cardiovascular Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtcvs.2004.04.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}