{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T20:05:55Z","timestamp":1784664355630,"version":"3.55.0"},"reference-count":21,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2005,10,1]],"date-time":"2005-10-01T00:00:00Z","timestamp":1128124800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,7,6]],"date-time":"2016-07-06T00:00:00Z","timestamp":1467763200000},"content-version":"vor","delay-in-days":3931,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Thoracic and Cardiovascular Surgery"],"published-print":{"date-parts":[[2005,10]]},"DOI":"10.1016\/j.jtcvs.2005.03.048","type":"journal-article","created":{"date-parts":[[2005,10,14]],"date-time":"2005-10-14T11:14:48Z","timestamp":1129288488000},"page":"1054-1061","source":"Crossref","is-referenced-by-count":7,"title":["Protein oxidation injury occurs during pediatric cardiopulmonary bypass"],"prefix":"10.25013","volume":"130","author":[{"given":"Meredith L.","family":"Sheil","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Luxford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Davies","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer K.","family":"Peat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graham","family":"Nunn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David S.","family":"Celermajer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtcvs.2005.03.048_bib1","doi-asserted-by":"crossref","first-page":"4780","DOI":"10.1021\/bi00069a012","article-title":"Protein-bound 3,4-dihydroxyphenylalanine is a major reductant formed during hydroxyl radical damage to proteins","volume":"32","author":"Gieseg","year":"1993","journal-title":"Biochemistry."},{"key":"10.1016\/j.jtcvs.2005.03.048_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1042\/bj3240001","article-title":"Biochemistry and pathology of radical-mediated protein oxidation","volume":"324","author":"Dean","year":"1997","journal-title":"Biochem J."},{"issue":"suppl","key":"10.1016\/j.jtcvs.2005.03.048_bib3","first-page":"S99","article-title":"Human studies related to protein oxidation","volume":"33","author":"Chevion","year":"2000","journal-title":"Free Radic Res."},{"key":"10.1016\/j.jtcvs.2005.03.048_bib4","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1016\/S0008-6363(00)00307-2","article-title":"Peroxynitrite induced nitration and inactivation of myofibrillar creatine kinase in experimental heart failure","volume":"49","author":"Mihm","year":"2001","journal-title":"Cardiovasc Res."},{"key":"10.1016\/j.jtcvs.2005.03.048_bib5","doi-asserted-by":"crossref","first-page":"1780","DOI":"10.1016\/S0891-5849(00)00235-5","article-title":"Cell signalling by reactive nitrogen and oxygen species in atherosclerosis","volume":"28","author":"Patel","year":"2000","journal-title":"Free Radic Biol Med."},{"key":"10.1016\/j.jtcvs.2005.03.048_bib6","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1042\/bj3301059","article-title":"The protein oxidation product 3,4 dihydroxyphenylalanine (DOPA) mediates oxidative DNA damage","volume":"330","author":"Morin","year":"1998","journal-title":"Biochem J."},{"key":"10.1016\/j.jtcvs.2005.03.048_bib7","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0022-5223(19)34848-2","article-title":"Effect of oxygen tension and cardiovascular operations on the myocardial antioxidant enzyme activities in patients with tetralogy of Fallot and aorta-coronary bypass","volume":"104","author":"Teoh","year":"1992","journal-title":"J Thorac Cardiovasc Surg."},{"key":"10.1016\/j.jtcvs.2005.03.048_bib8","first-page":"891","article-title":"Studies of hypoxemic\/reoxygenation injury without aortic clamping: II. Evidence for reoxygenation damage","volume":"110","author":"Ihnken","year":"1995","journal-title":"J Thorac Cardiovasc Surg."},{"key":"10.1016\/j.jtcvs.2005.03.048_bib9","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1016\/S0003-4975(97)00905-3","article-title":"Detrimental effects of cardiopulmonary bypass in cyanotic infants","volume":"64","author":"Allen","year":"1997","journal-title":"Ann Thorac Surg."},{"key":"10.1016\/j.jtcvs.2005.03.048_bib10","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/S0891-5849(99)00206-3","article-title":"Stable markers of oxidant damage to proteins and their application in the study of human disease","volume":"27","author":"Davies","year":"1999","journal-title":"Free Radic Biol Med."},{"key":"10.1016\/j.jtcvs.2005.03.048_bib11","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1161\/01.CIR.0000079867.56212.17","article-title":"Proteomics in cardiovascular biology and medicine","volume":"108","author":"Loscalzo","year":"2003","journal-title":"Circulation."},{"key":"10.1016\/j.jtcvs.2005.03.048_bib12","doi-asserted-by":"crossref","first-page":"6365","DOI":"10.1073\/pnas.96.11.6365","article-title":"Microtubule dysfunction by posttranslational nitrotyrosination of alpha-tubulin","volume":"96","author":"Eiserich","year":"1999","journal-title":"Proc Natl Acad Sci U S A."},{"key":"10.1016\/j.jtcvs.2005.03.048_bib13","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/sj.bjp.0704495","article-title":"Intracellular distribution of peroxynitrite during doxorubicin cardiomyopathy","volume":"135","author":"Mihm","year":"2002","journal-title":"Br J Pharmacol."},{"key":"10.1016\/j.jtcvs.2005.03.048_bib14","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1161\/01.CIR.104.2.174","article-title":"Impaired myofibrillar energetics and oxidative injury during human atrial fibrillation","volume":"104","author":"Mihm","year":"2001","journal-title":"Circulation."},{"key":"10.1016\/j.jtcvs.2005.03.048_bib15","first-page":"759","article-title":"Increased production of peroxidation products associated with cardiac operations","volume":"91","author":"Royston","year":"1986","journal-title":"J Cardiovasc Surg."},{"key":"10.1016\/j.jtcvs.2005.03.048_bib16","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1016\/S0003-4975(98)00727-9","article-title":"Effects of cardiopulmonary bypass on leukocytes and endothelial adhesion molecules","volume":"66","author":"Asimakopoulos","year":"1998","journal-title":"Ann Thorac Surg."},{"key":"10.1016\/j.jtcvs.2005.03.048_bib17","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/S0022-5223(19)34915-3","article-title":"Evidence for the role of neutrophils in reperfusion injury after cold cardioplegic ischaemia in neonatal lambs","volume":"103","author":"Kawata","year":"1992","journal-title":"J Thorac Cardiovasc Surg."},{"key":"10.1016\/j.jtcvs.2005.03.048_bib18","doi-asserted-by":"crossref","first-page":"S24","DOI":"10.1016\/S0003-4975(97)00958-2","article-title":"Ischemia-reperfusion injury","volume":"64","author":"Boyle","year":"1997","journal-title":"Ann Thorac Surg."},{"key":"10.1016\/j.jtcvs.2005.03.048_bib19","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1016\/S0022-5223(95)70013-7","article-title":"Studies of hypoxemic\/reoxygenation injury: with aortic clamping. XII. Delay of cardiac reoxygenation damage in the presence of cyanosis: a new concept of controlled cardiac reoxygenation","volume":"110","author":"Morita","year":"1995","journal-title":"J Thorac Cardiovasc Surg."},{"key":"10.1016\/j.jtcvs.2005.03.048_bib20","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/S0022-5223(97)70295-2","article-title":"Prevention of the hypoxic reoxygenation injury with the use of a leukocyte depleting filter","volume":"113","author":"Bolling","year":"1997","journal-title":"J Thorac Cardiovasc Surg."},{"key":"10.1016\/j.jtcvs.2005.03.048_bib21","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1021\/j150654a030","article-title":"Reactivity of OH with tyrosine in aqueous solution studied by pulse radiolysis","volume":"88","author":"Solar","year":"1984","journal-title":"J Phys Chem."}],"container-title":["The Journal of Thoracic and Cardiovascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022522305008780?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022522305008780?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,10]],"date-time":"2020-04-10T08:46:37Z","timestamp":1586508397000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022522305008780"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,10]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,10]]}},"alternative-id":["S0022522305008780"],"URL":"https:\/\/doi.org\/10.1016\/j.jtcvs.2005.03.048","relation":{},"ISSN":["0022-5223"],"issn-type":[{"value":"0022-5223","type":"print"}],"subject":[],"published":{"date-parts":[[2005,10]]}}}