{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T16:30:15Z","timestamp":1790008215636,"version":"4.0.1"},"reference-count":36,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2005,10,1]],"date-time":"2005-10-01T00:00:00Z","timestamp":1128124800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,7,6]],"date-time":"2016-07-06T00:00:00Z","timestamp":1467763200000},"content-version":"vor","delay-in-days":3931,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Thoracic and Cardiovascular Surgery"],"published-print":{"date-parts":[[2005,10]]},"DOI":"10.1016\/j.jtcvs.2005.06.029","type":"journal-article","created":{"date-parts":[[2005,10,14]],"date-time":"2005-10-14T07:14:48Z","timestamp":1129274088000},"page":"1094-1100","source":"Crossref","is-referenced-by-count":122,"title":["Systemic venous oxygen saturation after the Norwood procedure and childhood neurodevelopmental outcome"],"prefix":"10.25013","volume":"130","author":[{"given":"George M.","family":"Hoffman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen A.","family":"Mussatto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheryl L.","family":"Brosig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy S.","family":"Ghanayem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ndidiamaka","family":"Musa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond T.","family":"Fedderly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert D.B.","family":"Jaquiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James S.","family":"Tweddell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtcvs.2005.06.029_bib1","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1053\/j.pcsu.2004.02.019","article-title":"Neurodevelopmental outcomes in hypoplastic left heart syndrome","volume":"7","author":"Mahle","year":"2004","journal-title":"Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib2","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1016\/S0022-5223(03)01188-7","article-title":"Apolipoprotein E genotype and neurodevelopmental sequelae of infant cardiac surgery","volume":"126","author":"Gaynor","year":"2003","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib3","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1067\/mpd.2002.125227","article-title":"Predictors of developmental disabilities after open heart surgery in young children with congenital heart defects","volume":"141","author":"Limperopoulos","year":"2002","journal-title":"J Pediatr"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib4","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1136\/adc.72.5.418","article-title":"Incidence of neurological complications of surgery for congenital heart disease","volume":"72","author":"Fallon","year":"1995","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib5","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1097\/01.hco.0000153451.68212.68","article-title":"Central nervous system outcomes in children with complex congenital heart disease","volume":"20","author":"Wernovsky","year":"2005","journal-title":"Curr Opin Cardiol"},{"issue":"suppl I","key":"10.1016\/j.jtcvs.2005.06.029_bib6","first-page":"I109","article-title":"An MRI study of neurological injury before and after congenital heart surgery","volume":"106","author":"Mahle","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib7","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1177\/088307389701200501","article-title":"Cerebral hemodynamics and metabolism during infant cardiac surgery. Mechanisms of injury and strategies for protection","volume":"12","author":"du Plessis","year":"1997","journal-title":"J Child Neurol"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib8","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/S0003-4975(03)00468-5","article-title":"Early postoperative prediction of cerebral damage after pediatric cardiac surgery","volume":"76","author":"Trittenwein","year":"2003","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib9","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1016\/S0022-5223(03)00940-1","article-title":"The effect of duration of deep hypothermic circulatory arrest in infant heart surgery on late neurodevelopment","volume":"126","author":"Wypij","year":"2003","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib10","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1016\/j.jtcvs.2003.04.003","article-title":"The influence of hemodilution on outcome after hypothermic cardiopulmonary bypass","volume":"126","author":"Jonas","year":"2003","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib11","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1067\/mtc.2001.111206","article-title":"Developmental and neurologic effects of alpha-stat versus pH-stat strategies for deep hypothermic cardiopulmonary bypass in infants","volume":"121","author":"Bellinger","year":"2001","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib12","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1067\/mtc.2001.112338","article-title":"Comparison of neurologic outcome after deep hypothermic circulatory arrest with alpha-stat and pH-stat cardiopulmonary bypass in newborn pigs","volume":"121","author":"Priestley","year":"2001","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib13","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/S0095-5108(18)30151-9","article-title":"Neurologic complications of cardiac disease in the newborn","volume":"24","author":"du Plessis","year":"1997","journal-title":"Clin Perinatol"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib14","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1016\/j.ejcts.2004.08.008","article-title":"The short term effects of cardiopulmonary bypass on neurologic function in children and young adults","volume":"26","author":"Mahle","year":"2004","journal-title":"Eur J Cardiothorac Surg"},{"issue":"suppl 1","key":"10.1016\/j.jtcvs.2005.06.029_bib15","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1017\/S1047951105001198","article-title":"Detection and prevention of neurologic injury inn the intensive care unit","volume":"15","author":"Hoffman","year":"2005","journal-title":"Cardiol Young"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib16","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.1016\/S0003-4975(00)01349-7","article-title":"Patients at risk for low systemic oxygen delivery after the Norwood procedure","volume":"69","author":"Tweddell","year":"2000","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib17","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.jtcvs.2003.08.021","article-title":"Changes in cerebral and somatic oxygenation during stage 1 palliation of hypoplastic left heart syndrome using continuous regional cerebral perfusion","volume":"127","author":"Hoffman","year":"2004","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib18","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1016\/S0003-4975(00)01772-0","article-title":"Venous saturation and the anaerobic threshold in neonates after the Norwood procedure for hypoplastic left heart syndrome","volume":"70","author":"Hoffman","year":"2000","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib19","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1016\/0003-4975(95)00700-U","article-title":"Comparing two strategies of cardiopulmonary bypass cooling on jugular venous oxygen saturation in neonates and infants","volume":"60","author":"Kern","year":"1995","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib20","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1016\/S0022-5223(95)70026-9","article-title":"Blood gas management and degree of cooling","volume":"110","author":"Skaryak","year":"1995","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"suppl I","key":"10.1016\/j.jtcvs.2005.06.029_bib21","first-page":"I82","article-title":"Improved survival of patients undergoing palliation of hypoplastic left heart syndrome","volume":"106","author":"Tweddell","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib22","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1056\/NEJM199503023320901","article-title":"Developmental and neurologic status of children after heart surgery with hypothermic circulatory arrest or low-flow cardiopulmonary bypass","volume":"332","author":"Bellinger","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib23","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0095-5108(05)70077-4","article-title":"Long-term developmental outcome of children with complex congenital heart disease","volume":"28","author":"Mahle","year":"2001","journal-title":"Clin Perinatol"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib24","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/S0022-5223(97)70074-6","article-title":"Benefit of neurophysiologic monitoring for pediatric cardiac surgery","volume":"114","author":"Austin","year":"1997","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib25","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/j.jtcvs.2003.09.053","article-title":"Periventricular leukomalacia is common after neonatal cardiac surgery","volume":"127","author":"Galli","year":"2004","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib26","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/S0003-4975(03)01365-1","article-title":"Routine mechanical ventricular assist following the Norwood procedure\u2014improved neurologic outcome and excellent hospital survival","volume":"77","author":"Ungerleider","year":"2004","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib27","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1016\/0003-4975(93)90731-V","article-title":"Effect of deep hypothermia and circulatory arrest on cerebral blood flow and metabolism","volume":"56","author":"Greeley","year":"1993","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib28","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.jtcvs.2003.08.033","article-title":"The influence of pH strategy on cerebral and collateral circulation during hypothermic cardiopulmonary bypass in cyanotic patients with heart disease","volume":"127","author":"Sakamoto","year":"2004","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib29","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/S1092-9126(03)70017-9","article-title":"Optimizing response of the neonate and infant to cardiopulmonary bypass","volume":"6","author":"Ungerleider","year":"2003","journal-title":"Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib30","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0003-4975(98)01266-1","article-title":"Phenoxybenzamine improves systemic oxygen delivery after the Norwood procedure","volume":"67","author":"Tweddell","year":"1999","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib31","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/S0022-5223(03)01315-1","article-title":"Alteration of the critical arteriovenous oxygen saturation relationship by sustained afterload reduction after the Norwood procedure","volume":"127","author":"Hoffman","year":"2004","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib32","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1053\/j.pcsu.2005.01.005","article-title":"Noninvasive assessment of cardiac output","volume":"8","author":"Hoffman","year":"2005","journal-title":"Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib33","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.jtcvs.2003.08.021","article-title":"Changes in cerebral and somatic oxygenation during stage 1 palliation of hypoplastic left heart syndrome using continuous regional cerebral perfusion","volume":"127","author":"Wernovsky","year":"2004","journal-title":"J Thorac Cardiovasc Surg."},{"key":"10.1016\/j.jtcvs.2005.06.029_bib34","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1111\/j.1460-9592.2005.01404.x","article-title":"Near-infrared spectroscopic cerebral oxygenation reading in neonates and infants is associated with central venous oxygen saturation","volume":"15","author":"Weiss","year":"2005","journal-title":"Paediatr Anaesth"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib35","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1034\/j.1399-6576.2001.045006696.x","article-title":"Dynamic changes in cerebral oxygenation related to deep hypothermia and circulatory arrest evaluated by near-infrared spectroscopy","volume":"45","author":"Abdul-Khaliq","year":"2001","journal-title":"Acta Anaesthesiol Scand"},{"key":"10.1016\/j.jtcvs.2005.06.029_bib36","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1055\/s-2002-26698","article-title":"Cerebral oxygen monitoring during neonatal cardiopulmonary bypass and deep hypothermic circulatory arrest","volume":"50","author":"Abdul-Khaliq","year":"2002","journal-title":"Thorac Cardiovasc Surg"}],"container-title":["The Journal of Thoracic and Cardiovascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022522305010767?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022522305010767?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,3,31]],"date-time":"2019-03-31T06:05:28Z","timestamp":1554012328000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022522305010767"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,10]]},"references-count":36,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,10]]}},"alternative-id":["S0022522305010767"],"URL":"https:\/\/doi.org\/10.1016\/j.jtcvs.2005.06.029","relation":{},"ISSN":["0022-5223"],"issn-type":[{"value":"0022-5223","type":"print"}],"subject":[],"published":{"date-parts":[[2005,10]]}}}