{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T12:52:00Z","timestamp":1778158320394,"version":"3.51.4"},"reference-count":32,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2007,12,1]],"date-time":"2007-12-01T00:00:00Z","timestamp":1196467200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,12,1]],"date-time":"2007-12-01T00:00:00Z","timestamp":1196467200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,7,6]],"date-time":"2016-07-06T00:00:00Z","timestamp":1467763200000},"content-version":"vor","delay-in-days":3140,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jtcvsonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Thoracic and Cardiovascular Surgery"],"published-print":{"date-parts":[[2007,12]]},"DOI":"10.1016\/j.jtcvs.2007.07.049","type":"journal-article","created":{"date-parts":[[2007,11,14]],"date-time":"2007-11-14T17:04:10Z","timestamp":1195059850000},"page":"1477-1484","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":73,"title":["Feasibility of multimodality therapy including extended resections in stage IVA thymoma"],"prefix":"10.25013","volume":"134","author":[{"given":"James","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nabil P.","family":"Rizk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William D.","family":"Travis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Venkatraman E.","family":"Seshan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manjit S.","family":"Bains","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Dycoco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert J.","family":"Downey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raja M.","family":"Flores","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard J.","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valerie W.","family":"Rusch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtcvs.2007.07.049_bib1","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/0003-4975(95)00669-C","article-title":"Thymoma: a multivariate analysis of factors predicting survival","volume":"60","author":"Blumberg","year":"1995","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib2","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/S0003-4975(03)00555-1","article-title":"Therapy for thymic epithelial tumors: a clinical study of 1,320 patients from Japan","volume":"75","author":"Kondo","year":"2003","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib3","doi-asserted-by":"crossref","first-page":"2485","DOI":"10.1002\/1097-0142(19811201)48:11<2485::AID-CNCR2820481123>3.0.CO;2-R","article-title":"Follow-up study of thymomas with special reference to their clinical stages","volume":"48","author":"Masaoka","year":"1981","journal-title":"Cancer"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib4","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1016\/S0022-5223(03)00798-0","article-title":"Thymoma: a clinicopathologic study based on the new World Health Organization classification","volume":"126","author":"Nakagawa","year":"2003","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib5","first-page":"37","article-title":"Thymoma: a review of the clinical and pathological findings in 65 cases","volume":"46","author":"Sperling","year":"2003","journal-title":"Can J Surg"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib6","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1378\/chest.105.6.1884","article-title":"Intrathoracic chemothermotherapy following panpleuropneumonectomy for pleural dissemination of invasive thymoma","volume":"105","author":"Higashiyama","year":"1994","journal-title":"Chest"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib7","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1016\/S0022-5223(19)35673-9","article-title":"Thymoma: results with complete resection and adjuvant postoperative irradiation in 141 consecutive patients","volume":"95","author":"Nakahara","year":"1988","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib8","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1007\/BF00308904","article-title":"Complete excision and panpleuropneumonectomy resulting in long-term survival for a teenager with invasive thymoma: report of a case","volume":"22","author":"Nakahashi","year":"1992","journal-title":"Surg Today"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib9","first-page":"35","article-title":"[Surgical treatment of stage IVa thymoma.]","volume":"46","author":"Okada","year":"1993","journal-title":"Kyobu Geka"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib10","first-page":"949","article-title":"[Pleuropneumonectomy with combined resection of diaphragma, superior vena cava, and pericardium, for invasive thymoma with pleural dissemination]","volume":"44","author":"Shinada","year":"1991","journal-title":"Kyobu Geka"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib11","first-page":"1371","article-title":"[Pleuropneumonectomy with thymectomy for invasive thymoma with pleural disseminations\u2014a case report]","volume":"38","author":"Suzuki","year":"1990","journal-title":"Nippon Kyobu Geka Gakkai Zasshi"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib12","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/0003-4975(95)00983-3","article-title":"Surgical treatment for invasive thymoma, especially when the superior vena cava is invaded","volume":"61","author":"Yagi","year":"1996","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib13","first-page":"1000","article-title":"[Extrapleural pneumonectomy for thoracic malignancies]","volume":"57","author":"Yokoi","year":"2004","journal-title":"Kyobu Geka"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib14","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.lungcan.2003.09.022","article-title":"Multimodal management of stages III-IVa malignant thymoma","volume":"44","author":"Bretti","year":"2004","journal-title":"Lung Cancer"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib15","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.lungcan.2003.12.010","article-title":"Phase II study of multidisciplinary approach with induction chemotherapy, followed by surgical resection, radiation therapy, and consolidation chemotherapy for unresectable malignant thymomas: final report","volume":"44","author":"Kim","year":"2004","journal-title":"Lung Cancer"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib16","doi-asserted-by":"crossref","first-page":"1840","DOI":"10.1016\/j.athoracsur.2004.12.047","article-title":"Advanced stage thymomas and thymic carcinomas: results of multimodality treatments","volume":"79","author":"Lucchi","year":"2005","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib17","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/0003-4975(91)90478-9","article-title":"Thymoma: results of 241 operated cases","volume":"51","author":"Maggi","year":"1991","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib18","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/S0022-5223(19)34092-9","article-title":"Chemotherapy and operation for invasive thymoma","volume":"106","author":"Rea","year":"1993","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib19","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1016\/S0003-4975(03)01020-8","article-title":"Long-term outcome after multimodality treatment for Stage III thymic tumors","volume":"76","author":"Venuta","year":"2003","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib20","series-title":"Pathology and genetics: tumours of the lung, pleura, thymus and heart (WHO classification of tumours)","first-page":"196","article-title":"Combined thymic epithelial tumours","author":"M\u00fcller-Hermelink","year":"2004"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib21","unstructured":"RECIST, the National Cancer Institute. Response Evaluation Criteria In Solid Tumors. 2000. Available from: http:\/\/ctep.cancer.gove\/guidelines\/recist.html."},{"key":"10.1016\/j.jtcvs.2007.07.049_bib22","unstructured":"CTCAE, National Cancer Institute. Common terminology criteria for adverse events v.3.0. 2006. Available from: http:\/\/ctep.cancer.gov\/forms\/CTCAEv3.pdf."},{"key":"10.1016\/j.jtcvs.2007.07.049_bib23","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/0003-4975(94)91067-7","article-title":"The clamshell incision","volume":"58","author":"Bains","year":"1994","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib24","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/S1010-7940(99)00156-6","article-title":"Morbidity and validity of the hemiclamshell approach for thoracic surgery","volume":"16","author":"Lardinois","year":"1999","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib25","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.jtcvs.2004.02.021","article-title":"Prevention, early detection, and management of complications after 328 consecutive extrapleural pneumonectomies","volume":"128","author":"Sugarbaker","year":"2004","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib26","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1016\/j.athoracsur.2006.05.028","article-title":"Pleuropneumonectomy for the treatment of Masaoka Stage IV thymoma","volume":"82","author":"Wright","year":"2006","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib27","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1002\/jso.1146","article-title":"Recurrence of thymoma: clinicopathological features, re-operation, and outcome","volume":"78","author":"Haniuda","year":"2001","journal-title":"J Surg Oncol"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib28","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1067\/mtc.2001.116560","article-title":"A Phase II trial of surgical resection and adjuvant high dose hemithoracic radiation for malignant pleural mesothelioma","volume":"122","author":"Rusch","year":"2001","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib29","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1016\/S0360-3016(03)00287-6","article-title":"Hemithoracic radiation after extrapleural pneumonectomy for malignant pleural mesothelioma","volume":"56","author":"Yajnik","year":"2003","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib30","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/0046-8177(94)90008-6","article-title":"The clinicopathological correlation of epithelial subtyping in thymoma: a study of 112 consecutive cases","volume":"25","author":"Pan","year":"1994","journal-title":"Hum Pathol"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib31","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/S0022-5223(96)70265-9","article-title":"Prognostic factors and long-term results after thymoma resection: a series of 307 patients","volume":"112","author":"Regnard","year":"1996","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2007.07.049_bib32","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1097\/00000658-199910000-00012","article-title":"Clinical and pathologic predictors of survival in patients with thymoma","volume":"230","author":"Wilkins","year":"1999","journal-title":"Ann Surg"}],"container-title":["The Journal of Thoracic and Cardiovascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022522307013499?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022522307013499?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T16:42:33Z","timestamp":1758386553000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022522307013499"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,12]]},"references-count":32,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007,12]]}},"alternative-id":["S0022522307013499"],"URL":"https:\/\/doi.org\/10.1016\/j.jtcvs.2007.07.049","relation":{},"ISSN":["0022-5223"],"issn-type":[{"value":"0022-5223","type":"print"}],"subject":[],"published":{"date-parts":[[2007,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Feasibility of multimodality therapy including extended resections in stage IVA thymoma","name":"articletitle","label":"Article Title"},{"value":"The Journal of Thoracic and Cardiovascular Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtcvs.2007.07.049","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}