{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T10:20:43Z","timestamp":1789208443588,"version":"build-2803163510"},"reference-count":22,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,7,6]],"date-time":"2016-07-06T00:00:00Z","timestamp":1467763200000},"content-version":"vor","delay-in-days":2074,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jtcvsonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Thoracic and Cardiovascular Surgery"],"published-print":{"date-parts":[[2010,11]]},"DOI":"10.1016\/j.jtcvs.2010.08.005","type":"journal-article","created":{"date-parts":[[2010,10,15]],"date-time":"2010-10-15T04:26:07Z","timestamp":1287116767000},"page":"977-983","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Should asymptomatic enlarged thymus glands be resected?"],"prefix":"10.1016","volume":"140","author":[{"given":"Smit","family":"Singla","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leslie A.","family":"Litzky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larry R.","family":"Kaiser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph B.","family":"Shrager","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jtcvs.2010.08.005_bib1","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.jtcvs.2006.10.026","article-title":"The distribution of parenchyma, follicles, and lymphocyte subsets in thymus of patients with myasthenia gravis, with special reference to remission after thymectomy","volume":"133","author":"Mori","year":"2007","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2010.08.005_bib2","doi-asserted-by":"crossref","first-page":"447","DOI":"10.2174\/0929867043455972","article-title":"Cytokines in the thymus: production and biological effects","volume":"11","author":"Yarilin","year":"2004","journal-title":"Curr Med Chem"},{"key":"10.1016\/j.jtcvs.2010.08.005_bib3","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1111\/j.1749-6632.1998.tb09574.x","article-title":"Thymic endocrinology","volume":"840","author":"Hadden","year":"1998","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.jtcvs.2010.08.005_bib4","first-page":"718","article-title":"The thymus in autoimmune disease","volume":"63","author":"Irvine","year":"1970","journal-title":"Proc R Soc Med"},{"key":"10.1016\/j.jtcvs.2010.08.005_bib5","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/S0022-5223(19)35684-3","article-title":"\u201cMaximal\u201d thymectomy for myasthenia gravis","volume":"95","author":"Jaretzki","year":"1988","journal-title":"Results. J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2010.08.005_bib6","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1016\/j.athoracsur.2006.05.110","article-title":"Outcomes after 151 extended transcervical thymectomies for myasthenia gravis","volume":"82","author":"Shrager","year":"2006","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jtcvs.2010.08.005_bib7","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1016\/S0022-5223(96)70151-4","article-title":"Results of video-assisted thymectomy in patients with myasthenia gravis","volume":"112","author":"Mack","year":"1996","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jtcvs.2010.08.005_bib8","doi-asserted-by":"crossref","first-page":"1743","DOI":"10.1001\/jama.1983.03330370053031","article-title":"If nothing goes wrong, is everything all right? Interpreting zero numerators","volume":"249","author":"Hanley","year":"1983","journal-title":"JAMA"},{"key":"10.1016\/j.jtcvs.2010.08.005_bib9","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1148\/radiology.201.2.8888243","article-title":"Thymus in myasthenia gravis: comparison of CT and pathologic findings and clinical outcome after thymectomy","volume":"201","author":"Nicolaou","year":"1996","journal-title":"Radiology"},{"key":"10.1016\/j.jtcvs.2010.08.005_bib10","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1034\/j.1600-0455.2002.430407.x","article-title":"Thymic lesions and myasthenia gravis. Diagnosis based on mediastinal imaging and pathological findings","volume":"43","author":"Pirronti","year":"2002","journal-title":"Acta Radiol"},{"key":"10.1016\/j.jtcvs.2010.08.005_bib11","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.jocn.2003.10.023","article-title":"Comparative study of preoperative thymic imaging and pathology in patients with myasthenia gravis","volume":"11","author":"Yasukawa","year":"2004","journal-title":"J Clin Neurosci"},{"key":"10.1016\/j.jtcvs.2010.08.005_bib12","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1148\/radiology.142.1.7053521","article-title":"Computed tomography of the normal thymus","volume":"142","author":"Baron","year":"1982","journal-title":"Radiology"},{"key":"10.1016\/j.jtcvs.2010.08.005_bib13","doi-asserted-by":"crossref","first-page":"249","DOI":"10.2214\/ajr.145.2.249","article-title":"The thymus: reexamination of age-related changes in size and shape","volume":"145","author":"Francis","year":"1985","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.jtcvs.2010.08.005_bib14","doi-asserted-by":"crossref","first-page":"241","DOI":"10.2214\/ajr.141.2.241","article-title":"Age-related changes in the thymus gland: CT-pathologic correlation","volume":"141","author":"Moore","year":"1983","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.jtcvs.2010.08.005_bib15","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1102\/1470-7330.2005.0107","article-title":"Imaging of thymic disorders","volume":"5","author":"Bogot","year":"2005","journal-title":"Cancer Imaging"},{"key":"10.1016\/j.jtcvs.2010.08.005_bib16","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1148\/rg.262045213","article-title":"The thymus: a comprehensive review","volume":"26","author":"Nishino","year":"2006","journal-title":"Radiographics"},{"key":"10.1016\/j.jtcvs.2010.08.005_bib17","doi-asserted-by":"crossref","first-page":"383","DOI":"10.2302\/kjm.38.383","article-title":"Thymic abnormalities and autoimmune diseases","volume":"38","author":"Tsuchiya","year":"1989","journal-title":"Keio J Med"},{"key":"10.1016\/j.jtcvs.2010.08.005_bib18","doi-asserted-by":"crossref","first-page":"275","DOI":"10.2302\/kjm.24.275","article-title":"Thymus in Hashimoto's disease and focal chronic lymphoid thyroiditis","volume":"24","author":"Shimabukuro","year":"1975","journal-title":"Keio J Med"},{"key":"10.1016\/j.jtcvs.2010.08.005_bib19","first-page":"67","article-title":"Thymectomy in ulcerative colitis: a report of cases over a 13 year period","volume":"17","author":"Tsuchiya","year":"1991","journal-title":"Thymus"},{"key":"10.1016\/j.jtcvs.2010.08.005_bib20","first-page":"267","article-title":"Clinical examinations of thymic abnormalities and significance of thymectomy in the patients with autoimmune disease","volume":"9","author":"Yoshimatsu","year":"1989","journal-title":"Rinsho Kyobu Geka"},{"key":"10.1016\/j.jtcvs.2010.08.005_bib21","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.ejcts.2009.03.055","article-title":"Role of fluorine\u2013flurodeoxyglucose positron emission tomography\/computed tomography in preoperative assessment of anterior mediastinal masses","volume":"36","author":"Luzzi","year":"2009","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.jtcvs.2010.08.005_bib22","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1259\/bjr.74.885.740821","article-title":"FDG uptake in the morphologically normal thymus: comparison of FDG positron emission tomography and CT","volume":"74","author":"Nakahara","year":"2001","journal-title":"Br J Radiol"}],"container-title":["The Journal of Thoracic and Cardiovascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022522310008810?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022522310008810?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T16:48:16Z","timestamp":1758386896000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022522310008810"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11]]},"references-count":22,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["S0022522310008810"],"URL":"https:\/\/doi.org\/10.1016\/j.jtcvs.2010.08.005","relation":{},"ISSN":["0022-5223"],"issn-type":[{"value":"0022-5223","type":"print"}],"subject":[],"published":{"date-parts":[[2010,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Should asymptomatic enlarged thymus glands be resected?","name":"articletitle","label":"Article Title"},{"value":"The Journal of Thoracic and Cardiovascular Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jtcvs.2010.08.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}